Motif ID: STAT5A

Z-value: 0.731


Transcription factors associated with STAT5A:

Gene SymbolEntrez IDGene Name
STAT5A ENSG00000126561.12 STAT5A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_40440561-0.541.4e-01Click!


Activity profile for motif STAT5A.

activity profile for motif STAT5A


Sorted Z-values histogram for motif STAT5A

Sorted Z-values for motif STAT5A



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_207262578 1.273 ENST00000243611.5
ENST00000367076.3
C4BPB

complement component 4 binding protein, beta

chr1_+_207262627 1.141 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr2_-_38303218 1.139 ENST00000407341.1
ENST00000260630.3
CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

chr1_+_207262170 1.128 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr1_+_207262540 1.115 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr5_+_150400124 1.082 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
GPX3


glutathione peroxidase 3 (plasma)


chr1_-_159046617 0.895 ENST00000368130.4
AIM2
absent in melanoma 2
chr19_-_17516449 0.868 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr5_-_67730240 0.828 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr8_+_19759228 0.739 ENST00000520959.1
LPL
lipoprotein lipase
chr6_-_34524049 0.737 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr5_+_140579162 0.709 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr6_+_32407619 0.687 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr7_-_95225768 0.679 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr3_+_187086120 0.669 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr10_-_5652705 0.665 ENST00000425246.1
RP11-336A10.5
RP11-336A10.5
chr2_-_197675000 0.603 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr7_+_117864708 0.589 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ANKRD7



ankyrin repeat domain 7



chr2_+_149895207 0.551 ENST00000409876.1
LYPD6B
LY6/PLAUR domain containing 6B
chr6_+_147830362 0.551 ENST00000566741.1
SAMD5
sterile alpha motif domain containing 5
chr11_+_65779283 0.544 ENST00000312134.2
CST6
cystatin E/M
chr1_+_46640750 0.523 ENST00000372003.1
TSPAN1
tetraspanin 1
chr8_+_39770803 0.522 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr1_-_11107280 0.516 ENST00000400897.3
ENST00000400898.3
MASP2

mannan-binding lectin serine peptidase 2

chr2_+_33683109 0.509 ENST00000437184.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_149894968 0.507 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr10_-_5046042 0.498 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr19_-_56904799 0.492 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
ZNF582



zinc finger protein 582



chr16_+_19421803 0.490 ENST00000541464.1
TMC5
transmembrane channel-like 5
chr15_-_26108355 0.486 ENST00000356865.6
ATP10A
ATPase, class V, type 10A
chr5_+_32788945 0.484 ENST00000326958.1
AC026703.1
AC026703.1
chr4_+_86396321 0.483 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr2_+_33701707 0.477 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3


RAS guanyl releasing protein 3 (calcium and DAG-regulated)


chr7_+_139529040 0.455 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1


thromboxane A synthase 1 (platelet)


chr22_+_21128167 0.450 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_-_49737184 0.449 ENST00000508934.1
ENST00000303221.5
EMB

embigin

chr19_-_43709703 0.443 ENST00000599391.1
ENST00000244295.9
PSG4

pregnancy specific beta-1-glycoprotein 4

chr6_+_122793058 0.443 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr4_-_89080003 0.441 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr7_+_139528952 0.439 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1



thromboxane A synthase 1 (platelet)



chr19_-_43709772 0.434 ENST00000596907.1
ENST00000451895.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr18_-_14970301 0.427 ENST00000580867.1
RP11-527H14.3
RP11-527H14.3
chr4_-_89079817 0.421 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr4_-_89080362 0.412 ENST00000503830.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr6_+_84222220 0.411 ENST00000369700.3
PRSS35
protease, serine, 35
chr2_+_65216462 0.410 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr9_-_19149276 0.403 ENST00000434144.1
PLIN2
perilipin 2
chr16_+_14396121 0.402 ENST00000570945.1
RP11-65J21.3
RP11-65J21.3
chr6_+_123038689 0.400 ENST00000354275.2
ENST00000368446.1
PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr6_-_56716686 0.399 ENST00000520645.1
DST
dystonin
chr5_+_173763250 0.398 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1


RP11-267A15.1


chr2_-_179672142 0.392 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr3_-_185270342 0.391 ENST00000424591.2
LIPH
lipase, member H
chr4_-_76957214 0.390 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chrX_-_55515635 0.389 ENST00000500968.3
USP51
ubiquitin specific peptidase 51
chr16_+_30996502 0.388 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7




hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7




chr4_+_75858290 0.388 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr6_+_168434678 0.383 ENST00000496008.1
KIF25
kinesin family member 25
chr8_-_120651020 0.382 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr3_-_182881595 0.380 ENST00000476015.1
LAMP3
lysosomal-associated membrane protein 3
chr2_-_145188137 0.377 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr4_+_155484103 0.368 ENST00000302068.4
FGB
fibrinogen beta chain
chr19_+_36203830 0.366 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr2_+_186603545 0.358 ENST00000424728.1
FSIP2
fibrous sheath interacting protein 2
chr6_+_44126545 0.353 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11


calpain 11


chr15_+_50474385 0.350 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr12_-_45270077 0.349 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr2_-_204398141 0.348 ENST00000428637.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr12_+_113416191 0.347 ENST00000342315.4
ENST00000392583.2
OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

chr17_-_15501932 0.346 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr12_-_111126910 0.343 ENST00000242607.8
HVCN1
hydrogen voltage-gated channel 1
chr3_+_69811858 0.339 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr11_-_104916034 0.336 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16


caspase recruitment domain family, member 16


chr4_-_40517984 0.332 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr4_+_126237554 0.332 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr3_-_171489085 0.331 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr4_+_47487285 0.328 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr13_+_24144509 0.327 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_-_166651152 0.327 ENST00000431484.1
ENST00000412248.1
GALNT3

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)

chr7_+_117120017 0.325 ENST00000003084.6
ENST00000454343.1
CFTR

cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

chr3_+_171844762 0.325 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr16_+_19422035 0.321 ENST00000381414.4
ENST00000396229.2
TMC5

transmembrane channel-like 5

chr9_-_119162885 0.318 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr17_-_39928106 0.317 ENST00000540235.1
JUP
junction plakoglobin
chr6_+_26158343 0.315 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr8_+_32405728 0.314 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1




neuregulin 1




chr17_-_33864772 0.314 ENST00000361112.4
SLFN12L
schlafen family member 12-like
chr1_+_26503894 0.313 ENST00000361530.6
ENST00000374253.5
CNKSR1

connector enhancer of kinase suppressor of Ras 1

chr4_+_86396265 0.312 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr8_-_110660975 0.310 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr2_-_152955537 0.308 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr8_-_27469196 0.306 ENST00000546343.1
ENST00000560566.1
CLU

clusterin

chr8_-_17555164 0.305 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr15_+_50474412 0.305 ENST00000380902.4
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr1_+_149754227 0.303 ENST00000444948.1
ENST00000369168.4
FCGR1A

Fc fragment of IgG, high affinity Ia, receptor (CD64)

chr12_+_113416340 0.302 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr8_-_27468842 0.299 ENST00000523500.1
CLU
clusterin
chr3_+_185046676 0.299 ENST00000428617.1
ENST00000443863.1
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr8_+_8559406 0.296 ENST00000519106.1
CLDN23
claudin 23
chr3_-_185538849 0.293 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_152955213 0.292 ENST00000427385.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr10_-_105238997 0.291 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chr12_-_95942563 0.291 ENST00000549639.1
ENST00000551837.1
USP44

ubiquitin specific peptidase 44

chr2_+_128405655 0.290 ENST00000423019.1
GPR17
G protein-coupled receptor 17
chr8_-_27468945 0.288 ENST00000405140.3
CLU
clusterin
chr1_+_9242221 0.283 ENST00000412639.2
RP3-510D11.2
RP3-510D11.2
chr4_+_108815402 0.283 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr1_+_201979645 0.282 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr8_-_27468717 0.281 ENST00000520796.1
ENST00000520491.1
CLU

clusterin

chr6_+_33048222 0.281 ENST00000428835.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr8_-_27469383 0.279 ENST00000519742.1
CLU
clusterin
chr1_+_207262881 0.277 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr11_-_94965667 0.275 ENST00000542176.1
ENST00000278499.2
SESN3

sestrin 3

chr4_+_155484155 0.275 ENST00000509493.1
FGB
fibrinogen beta chain
chr1_-_173020056 0.274 ENST00000239468.2
ENST00000404377.3
TNFSF18

tumor necrosis factor (ligand) superfamily, member 18

chr2_-_166651191 0.273 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr18_-_74839891 0.272 ENST00000581878.1
MBP
myelin basic protein
chr16_-_19897455 0.271 ENST00000568214.1
ENST00000569479.1
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr17_-_72619869 0.270 ENST00000392619.1
ENST00000426295.2
CD300E

CD300e molecule

chr17_-_29641104 0.270 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr17_-_29641084 0.267 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr19_-_6767516 0.265 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr17_-_39780634 0.265 ENST00000577817.2
KRT17
keratin 17
chr21_-_35883613 0.265 ENST00000337385.3
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr5_+_59783540 0.265 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr2_-_208634287 0.263 ENST00000295417.3
FZD5
frizzled family receptor 5
chr19_-_44388116 0.260 ENST00000587539.1
ZNF404
zinc finger protein 404
chr12_-_45269430 0.259 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr16_-_29479154 0.258 ENST00000549950.1
RP11-345J4.3
Uncharacterized protein
chr12_-_95942613 0.256 ENST00000393091.2
USP44
ubiquitin specific peptidase 44
chr9_-_114557207 0.256 ENST00000374287.3
ENST00000374283.5
C9orf84

chromosome 9 open reading frame 84

chr3_+_183894566 0.252 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr3_+_184053703 0.250 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
FAM131A



family with sequence similarity 131, member A



chr17_-_15502111 0.250 ENST00000354433.3
CDRT1
CMT1A duplicated region transcript 1
chr12_+_21207503 0.249 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr10_-_33625154 0.248 ENST00000265371.4
NRP1
neuropilin 1
chr5_+_140753444 0.247 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr4_-_40631859 0.247 ENST00000295971.7
ENST00000319592.4
RBM47

RNA binding motif protein 47

chr4_-_52883786 0.245 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr8_-_110615669 0.245 ENST00000533394.1
SYBU
syntabulin (syntaxin-interacting)
chr12_+_113416265 0.243 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr4_-_168155169 0.242 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr12_-_45269251 0.241 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr17_-_72968837 0.240 ENST00000581676.1
HID1
HID1 domain containing
chr3_+_185000729 0.240 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
MAP3K13




mitogen-activated protein kinase kinase kinase 13




chr11_+_76493294 0.240 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr11_-_58378759 0.240 ENST00000601906.1
AP001350.1
Uncharacterized protein
chr5_-_147211226 0.239 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr6_-_31689456 0.239 ENST00000495859.1
ENST00000375819.2
LY6G6C

lymphocyte antigen 6 complex, locus G6C

chr2_+_102803433 0.239 ENST00000264257.2
ENST00000441515.2
IL1RL2

interleukin 1 receptor-like 2

chr11_+_121461097 0.237 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_35168633 0.236 ENST00000505365.2
ZNF302
zinc finger protein 302
chr19_+_44764031 0.234 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
ZNF233



zinc finger protein 233



chr19_+_35225060 0.231 ENST00000599244.1
ENST00000392232.3
ZNF181

zinc finger protein 181

chr7_+_129984630 0.231 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chr19_+_35168567 0.230 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302





zinc finger protein 302





chr2_-_128399706 0.230 ENST00000426981.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr11_+_74811578 0.230 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr22_-_36018569 0.228 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr5_+_178450753 0.228 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
ZNF879


zinc finger protein 879


chr8_+_38586068 0.228 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1


transforming, acidic coiled-coil containing protein 1


chr21_-_35883541 0.228 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr1_+_167599330 0.227 ENST00000367854.3
ENST00000361496.3
RCSD1

RCSD domain containing 1

chr3_-_13461807 0.225 ENST00000254508.5
NUP210
nucleoporin 210kDa
chr1_-_41328018 0.223 ENST00000372638.2
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr14_+_88471468 0.222 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr3_+_183853052 0.222 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
EIF2B5


eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa


chr17_-_26697304 0.222 ENST00000536498.1
VTN
vitronectin
chr12_-_11139511 0.221 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr12_+_10366223 0.220 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_-_28973037 0.219 ENST00000377179.3
ZNF311
zinc finger protein 311
chr5_-_140013275 0.219 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14


CD14 molecule


chr7_+_139529085 0.218 ENST00000539806.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr20_-_5591626 0.215 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chrX_-_106146547 0.215 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr19_+_35168547 0.214 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302


zinc finger protein 302


chr4_-_40632605 0.214 ENST00000514014.1
RBM47
RNA binding motif protein 47
chrX_-_153775426 0.214 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr21_-_45660723 0.213 ENST00000344330.4
ENST00000407780.3
ENST00000400379.3
ICOSLG


inducible T-cell co-stimulator ligand


chr3_-_93747425 0.213 ENST00000315099.2
STX19
syntaxin 19
chr19_+_12203100 0.211 ENST00000596883.1
ZNF788
zinc finger family member 788
chr18_-_7117813 0.210 ENST00000389658.3
LAMA1
laminin, alpha 1
chr15_+_45021183 0.208 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr3_-_145940126 0.208 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr12_-_111127201 0.207 ENST00000548312.1
HVCN1
hydrogen voltage-gated channel 1
chr12_-_11150474 0.207 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr6_+_27107053 0.206 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr19_+_17516624 0.206 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9


CTD-2521M24.9


chr4_-_168155417 0.205 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr19_-_35323762 0.205 ENST00000590963.1
CTC-523E23.4
CTC-523E23.4
chr19_-_44809121 0.204 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235



zinc finger protein 235



chr10_+_104629199 0.203 ENST00000369880.3
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr20_-_23030296 0.203 ENST00000377103.2
THBD
thrombomodulin
chr5_-_53115506 0.202 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1

CTD-2081C10.1

chr19_-_51017127 0.200 ENST00000389208.4
ASPDH
aspartate dehydrogenase domain containing
chr3_+_98216448 0.199 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr8_+_124194752 0.198 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr7_-_142198049 0.198 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr4_-_168155300 0.198 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_+_10365404 0.196 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1





GABA(A) receptor-associated protein like 1






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 0.9 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.3 1.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.5 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.5 GO:0036269 swimming behavior(GO:0036269)
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.7 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.7 GO:0034371 chylomicron remodeling(GO:0034371)
0.1 0.8 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.3 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.4 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.7 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.1 1.1 GO:0070269 pyroptosis(GO:0070269)
0.1 1.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.3 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.9 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.2 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.1 0.4 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.1 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.2 GO:1904604 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.1 0.2 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0090427 regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427)
0.0 0.2 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.3 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.4 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.1 GO:2001113 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.6 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.6 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.5 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.0 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.0 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.5 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0015886 heme transport(GO:0015886)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.3 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 4.7 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.7 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.5 GO:0001855 complement component C4b binding(GO:0001855)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 1.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 1.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.9 GO:0031433 telethonin binding(GO:0031433)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0070330 aromatase activity(GO:0070330)
0.1 0.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.4 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0005261 cation channel activity(GO:0005261)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004912 interleukin-3 receptor activity(GO:0004912)
0.0 0.0 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0016746 transferase activity, transferring acyl groups(GO:0016746)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.1 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.9 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.5 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.5 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation