Motif ID: STAT4

Z-value: 0.457


Transcription factors associated with STAT4:

Gene SymbolEntrez IDGene Name
STAT4 ENSG00000138378.13 STAT4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
STAT4hg19_v2_chr2_-_192016316_192016325-0.872.2e-03Click!


Activity profile for motif STAT4.

activity profile for motif STAT4


Sorted Z-values histogram for motif STAT4

Sorted Z-values for motif STAT4



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_137793826 1.091 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr12_-_55367361 0.551 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1


thymocyte expressed, positive selection associated 1


chr17_-_46682321 0.509 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr10_-_62060232 0.438 ENST00000503925.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_41740181 0.429 ENST00000442711.1
INHBA
inhibin, beta A
chr12_-_55367331 0.426 ENST00000526532.1
ENST00000532757.1
TESPA1

thymocyte expressed, positive selection associated 1

chr3_+_111260980 0.407 ENST00000438817.2
CD96
CD96 molecule
chr5_+_53686658 0.361 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr2_-_202563414 0.341 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4


membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)


chr14_-_80678512 0.338 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr5_-_64777733 0.337 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr2_-_202563351 0.325 ENST00000602867.1
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_16085263 0.323 ENST00000483633.2
ENST00000502739.1
ENST00000431771.2
FBLIM1


filamin binding LIM protein 1


chr3_-_50649192 0.307 ENST00000443053.2
ENST00000348721.3
CISH

cytokine inducible SH2-containing protein

chr2_-_202562774 0.290 ENST00000396886.3
ENST00000409143.1
MPP4

membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)

chr11_+_117070904 0.258 ENST00000529792.1
TAGLN
transgelin
chr15_+_63340858 0.224 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr15_-_75660919 0.221 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1






mannosidase, alpha, class 2C, member 1






chr2_-_84686552 0.221 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr15_+_63340647 0.221 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr15_+_63340775 0.216 ENST00000559281.1
ENST00000317516.7
TPM1

tropomyosin 1 (alpha)

chr2_-_75796837 0.213 ENST00000233712.1
EVA1A
eva-1 homolog A (C. elegans)
chr15_+_63340734 0.213 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr18_+_6729725 0.212 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chr18_+_6729698 0.207 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr17_+_1666108 0.195 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_80782219 0.186 ENST00000553594.1
DIO2
deiodinase, iodothyronine, type II
chr16_-_67260691 0.181 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29


leucine rich repeat containing 29


chr4_+_169575875 0.180 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr3_+_111260954 0.178 ENST00000283285.5
CD96
CD96 molecule
chr6_+_32821924 0.172 ENST00000374859.2
ENST00000453265.2
PSMB9

proteasome (prosome, macropain) subunit, beta type, 9

chr3_+_111260856 0.167 ENST00000352690.4
CD96
CD96 molecule
chr1_-_8000872 0.166 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr3_-_71114066 0.161 ENST00000485326.2
FOXP1
forkhead box P1
chr21_+_38593701 0.160 ENST00000440629.1
AP001432.14
AP001432.14
chr1_+_155146318 0.160 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46





tripartite motif containing 46





chr11_+_33563821 0.153 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L


KIAA1549-like


chr10_-_6622201 0.152 ENST00000539722.1
ENST00000397176.2
PRKCQ

protein kinase C, theta

chr3_-_156534754 0.148 ENST00000472943.1
ENST00000473352.1
LINC00886

long intergenic non-protein coding RNA 886

chr16_-_67517716 0.147 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr5_+_32585605 0.146 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1



SUB1 homolog (S. cerevisiae)



chr2_-_190044480 0.146 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr1_-_205391178 0.144 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr16_-_67260901 0.141 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29


AC040160.1
leucine rich repeat containing 29


Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr5_-_64777685 0.141 ENST00000536360.1
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr9_+_72658490 0.141 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr13_-_45915221 0.136 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1




tumor protein, translationally-controlled 1




chr1_-_231005310 0.136 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr14_+_100240019 0.134 ENST00000556199.1
EML1
echinoderm microtubule associated protein like 1
chr9_-_134151915 0.133 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr17_+_7358889 0.128 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr1_-_161279749 0.125 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ


myelin protein zero


chr10_+_106028923 0.121 ENST00000338595.2
GSTO2
glutathione S-transferase omega 2
chr1_+_66796401 0.118 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_34685805 0.113 ENST00000508315.1
RAI14
retinoic acid induced 14
chr3_+_5020801 0.113 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr11_+_5509915 0.113 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr7_+_31569365 0.111 ENST00000454513.1
ENST00000451887.2
CCDC129

coiled-coil domain containing 129

chr3_+_155838337 0.108 ENST00000490337.1
ENST00000389636.5
KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr12_+_80750652 0.101 ENST00000550182.1
OTOGL
otogelin-like
chr1_-_68299130 0.098 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr10_+_6625733 0.097 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1

PRKCQ antisense RNA 1

chr22_-_38349552 0.094 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23




chromosome 22 open reading frame 23




chr13_-_30160925 0.093 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_+_6625605 0.092 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1

PRKCQ antisense RNA 1

chr5_-_16509101 0.091 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr15_-_66084621 0.089 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr13_+_100153665 0.089 ENST00000376387.4
TM9SF2
transmembrane 9 superfamily member 2
chr15_-_60690163 0.089 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2



















annexin A2



















chr15_+_57998821 0.088 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr15_+_57998923 0.087 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr6_-_110011718 0.086 ENST00000532976.1
AK9
adenylate kinase 9
chr14_+_56127960 0.085 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr22_-_50699701 0.082 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr12_-_122658746 0.082 ENST00000377035.1
IL31
interleukin 31
chr18_-_67629015 0.081 ENST00000579496.1
CD226
CD226 molecule
chr6_-_136610911 0.080 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1





BCL2-associated transcription factor 1





chr11_+_33563618 0.079 ENST00000526400.1
KIAA1549L
KIAA1549-like
chr21_-_35773370 0.079 ENST00000410005.1
AP000322.54
chromosome 21 open reading frame 140
chr14_+_56127989 0.077 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr1_+_64014588 0.077 ENST00000371086.2
ENST00000340052.3
DLEU2L

deleted in lymphocytic leukemia 2-like

chr3_+_159570722 0.077 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr15_-_60690932 0.077 ENST00000559818.1
ANXA2
annexin A2
chr6_-_110011704 0.076 ENST00000448084.2
AK9
adenylate kinase 9
chr11_+_6942205 0.076 ENST00000317834.3
OR2D3
olfactory receptor, family 2, subfamily D, member 3
chrX_-_70474910 0.076 ENST00000373988.1
ENST00000373998.1
ZMYM3

zinc finger, MYM-type 3

chrX_+_149861836 0.076 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1





myotubularin related protein 1





chr4_-_187476721 0.075 ENST00000307161.5
MTNR1A
melatonin receptor 1A
chr11_-_118436707 0.075 ENST00000264020.2
ENST00000264021.3
IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chr3_+_15468862 0.073 ENST00000396842.2
EAF1
ELL associated factor 1
chr22_-_31536480 0.073 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr3_-_196242233 0.072 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chrX_+_114874727 0.072 ENST00000543070.1
PLS3
plastin 3
chr14_+_20811722 0.071 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr14_+_20811766 0.070 ENST00000250416.5
ENST00000527915.1
PARP2

poly (ADP-ribose) polymerase 2

chr17_-_42994283 0.070 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr15_+_67458357 0.070 ENST00000537194.2
SMAD3
SMAD family member 3
chr10_+_17794251 0.070 ENST00000377495.1
ENST00000338221.5
TMEM236

transmembrane protein 236

chr13_-_26795840 0.070 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6


ring finger protein (C3H2C3 type) 6


chr14_-_81408031 0.069 ENST00000216517.6
CEP128
centrosomal protein 128kDa
chr15_+_65843130 0.068 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_45430105 0.068 ENST00000430399.1
LARS2
leucyl-tRNA synthetase 2, mitochondrial
chr20_-_18774614 0.068 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr3_-_137851220 0.066 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr6_-_32811771 0.066 ENST00000395339.3
ENST00000374882.3
PSMB8

proteasome (prosome, macropain) subunit, beta type, 8

chr2_-_238333919 0.066 ENST00000409162.1
AC112721.1
Uncharacterized protein
chr17_-_38928414 0.066 ENST00000335552.4
KRT26
keratin 26
chr16_+_66600294 0.065 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CMTM1










CKLF-like MARVEL transmembrane domain containing 1










chrX_+_24711997 0.065 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr6_+_108977520 0.064 ENST00000540898.1
FOXO3
forkhead box O3
chrX_+_107288197 0.063 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr16_+_58283814 0.063 ENST00000443128.2
ENST00000219299.4
CCDC113

coiled-coil domain containing 113

chr14_-_81408063 0.063 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr3_+_45429998 0.063 ENST00000265537.3
ENST00000415258.1
ENST00000431023.1
ENST00000414984.1
LARS2



leucyl-tRNA synthetase 2, mitochondrial



chr15_+_64680003 0.062 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr1_+_109265033 0.061 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr3_-_15469045 0.061 ENST00000450816.2
METTL6
methyltransferase like 6
chr3_-_57678772 0.061 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr6_+_134210243 0.060 ENST00000367882.4
TCF21
transcription factor 21
chr1_-_144364246 0.060 ENST00000540273.1
PPIAL4B
peptidylprolyl isomerase A (cyclophilin A)-like 4B
chr16_+_24549014 0.059 ENST00000564314.1
ENST00000567686.1
RBBP6

retinoblastoma binding protein 6

chr3_+_122399444 0.058 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr14_-_20881579 0.058 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
TEP1


telomerase-associated protein 1


chr1_+_149553003 0.057 ENST00000369222.3
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr10_-_50396357 0.056 ENST00000453436.1
ENST00000474718.1
C10orf128

chromosome 10 open reading frame 128

chr12_+_14518598 0.055 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP




activating transcription factor 7 interacting protein




chr3_+_122399697 0.054 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr17_-_77924627 0.054 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chr6_+_31082603 0.054 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr11_-_64490634 0.052 ENST00000377559.3
ENST00000265459.6
NRXN2

neurexin 2

chr3_-_15469006 0.051 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6


methyltransferase like 6


chr3_-_148939598 0.051 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chrX_+_107288239 0.051 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr12_+_26164645 0.050 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr16_+_4674814 0.050 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1




mahogunin ring finger 1, E3 ubiquitin protein ligase




chr14_-_36645674 0.050 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr3_-_114866084 0.049 ENST00000357258.3
ZBTB20
zinc finger and BTB domain containing 20
chr3_+_130064359 0.049 ENST00000432398.2
ENST00000265379.6
COL6A5

collagen, type VI, alpha 5

chr11_+_20044375 0.048 ENST00000525322.1
ENST00000530408.1
NAV2

neuron navigator 2

chr17_-_5323480 0.048 ENST00000573584.1
NUP88
nucleoporin 88kDa
chr1_+_68150744 0.048 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr16_-_1660662 0.045 ENST00000569646.1
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr11_+_12302492 0.044 ENST00000533534.1
MICALCL
MICAL C-terminal like
chr20_-_62738524 0.043 ENST00000369768.1
NPBWR2
neuropeptides B/W receptor 2
chr3_+_15469058 0.043 ENST00000432764.2
EAF1
ELL associated factor 1
chr16_-_46782221 0.043 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr6_-_32821599 0.042 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_104404644 0.042 ENST00000462202.2
TRIM8
tripartite motif containing 8
chr3_+_38179969 0.041 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
MYD88





myeloid differentiation primary response 88





chr16_+_4674787 0.039 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr15_-_100882191 0.039 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr12_+_20848377 0.038 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1


solute carrier organic anion transporter family, member 1C1


chr16_-_20338748 0.038 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
GP2





glycoprotein 2 (zymogen granule membrane)





chr20_+_5731083 0.037 ENST00000445603.1
ENST00000442185.1
C20orf196

chromosome 20 open reading frame 196

chr12_+_113587558 0.037 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chrX_+_144908928 0.037 ENST00000408967.2
TMEM257
transmembrane protein 257
chr12_+_70636765 0.037 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2



CCR4-NOT transcription complex, subunit 2



chr1_-_143767881 0.036 ENST00000419275.1
PPIAL4G
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr20_+_39657454 0.036 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chrX_-_46187069 0.035 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr11_+_64059464 0.034 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr4_-_140477928 0.033 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr11_+_20044096 0.033 ENST00000533917.1
NAV2
neuron navigator 2
chr11_-_111636772 0.033 ENST00000531373.1
PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
chr5_-_39274617 0.033 ENST00000510188.1
FYB
FYN binding protein
chr5_+_140227048 0.032 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr4_+_130017268 0.031 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33


chromosome 4 open reading frame 33


chr6_-_49712091 0.031 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr1_-_162346657 0.031 ENST00000367935.5
C1orf111
chromosome 1 open reading frame 111
chr14_-_21270561 0.030 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr7_-_42971759 0.030 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
PSMA2


proteasome (prosome, macropain) subunit, alpha type, 2


chr10_-_104179682 0.029 ENST00000406432.1
PSD
pleckstrin and Sec7 domain containing
chr12_+_53443963 0.028 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr3_-_164875850 0.028 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr18_+_18822216 0.027 ENST00000269218.6
GREB1L
growth regulation by estrogen in breast cancer-like
chr5_+_40909354 0.027 ENST00000313164.9
C7
complement component 7
chr10_+_115312766 0.026 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr1_+_202431859 0.026 ENST00000391959.3
ENST00000367270.4
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr3_-_155461515 0.026 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr1_-_33502441 0.025 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2




adenylate kinase 2




chr20_-_49308048 0.024 ENST00000327979.2
FAM65C
family with sequence similarity 65, member C
chr4_-_155533787 0.024 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr12_+_20848282 0.024 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr20_+_5731027 0.023 ENST00000378979.4
ENST00000303142.6
C20orf196

chromosome 20 open reading frame 196

chr1_+_59250815 0.023 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2

long intergenic non-protein coding RNA 1135

chr11_+_64216546 0.022 ENST00000316124.2
AP003774.4
HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
chr4_-_140005443 0.022 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2


E74-like factor 2 (ets domain transcription factor)


chr1_-_144994840 0.022 ENST00000369351.3
ENST00000369349.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr12_+_20848486 0.022 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr1_+_153651078 0.020 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr14_-_21924209 0.019 ENST00000557364.1
CHD8
chromodomain helicase DNA binding protein 8
chrX_+_100646190 0.019 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr14_+_55034599 0.019 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr5_+_73109339 0.018 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr14_-_21490590 0.018 ENST00000557633.1
NDRG2
NDRG family member 2
chr12_+_56435637 0.017 ENST00000356464.5
ENST00000552361.1
RPS26

ribosomal protein S26

chr6_+_46761118 0.017 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr1_-_144994909 0.017 ENST00000369347.4
ENST00000369354.3
PDE4DIP

phosphodiesterase 4D interacting protein

chr22_+_24551765 0.016 ENST00000337989.7
CABIN1
calcineurin binding protein 1
chr3_-_126327398 0.016 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.2 1.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 1.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.2 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.0 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.9 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction