Motif ID: SRF

Z-value: 0.674


Transcription factors associated with SRF:

Gene SymbolEntrez IDGene Name
SRF ENSG00000112658.6 SRF

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SRFhg19_v2_chr6_+_43139037_431390940.684.6e-02Click!


Activity profile for motif SRF.

activity profile for motif SRF


Sorted Z-values histogram for motif SRF

Sorted Z-values for motif SRF



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_74120094 1.987 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2




actin, gamma 2, smooth muscle, enteric




chr13_-_46742630 1.776 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_121379739 1.081 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr19_+_11650709 0.862 ENST00000586059.1
CNN1
calponin 1, basic, smooth muscle
chr17_-_46671323 0.777 ENST00000239151.5
HOXB5
homeobox B5
chr3_-_46904946 0.664 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_-_46904918 0.580 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_+_16085263 0.551 ENST00000483633.2
ENST00000502739.1
ENST00000431771.2
FBLIM1


filamin binding LIM protein 1


chr6_+_151561506 0.538 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561085 0.529 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr12_+_54426637 0.468 ENST00000312492.2
HOXC5
homeobox C5
chr3_-_52486841 0.466 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr9_-_79520989 0.458 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2


prune homolog 2 (Drosophila)


chr17_-_42875115 0.452 ENST00000591137.1
CTC-296K1.4
CTC-296K1.4
chr15_+_83776324 0.421 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1



transmembrane 6 superfamily member 1



chr12_+_52445191 0.386 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr19_-_36247910 0.384 ENST00000587965.1
ENST00000004982.3
HSPB6

heat shock protein, alpha-crystallin-related, B6

chr11_+_117070037 0.355 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr7_-_559853 0.341 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr3_-_99595037 0.339 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr3_-_99594948 0.328 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr19_-_45826125 0.321 ENST00000221476.3
CKM
creatine kinase, muscle
chr17_+_50939459 0.303 ENST00000412360.1
AC102948.2
Uncharacterized protein
chr1_+_16085244 0.275 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr2_-_73520667 0.260 ENST00000545030.1
ENST00000436467.2
EGR4

early growth response 4

chr3_-_157221357 0.255 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr3_-_157221380 0.227 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr1_+_47881744 0.226 ENST00000335071.2
FOXE3
forkhead box E3
chr2_-_231989808 0.224 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr19_-_17356697 0.220 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr9_+_36136700 0.191 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLIPR2


GLI pathogenesis-related 2


chr13_+_42614176 0.189 ENST00000540693.1
DGKH
diacylglycerol kinase, eta
chr3_-_71294304 0.178 ENST00000498215.1
FOXP1
forkhead box P1
chr6_-_99797522 0.176 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr13_+_27825446 0.176 ENST00000311549.6
RPL21
ribosomal protein L21
chr13_+_27825706 0.176 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21


ribosomal protein L21


chr16_+_30383613 0.164 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr12_+_4382917 0.163 ENST00000261254.3
CCND2
cyclin D2
chr7_+_149416439 0.157 ENST00000497895.1
KRBA1
KRAB-A domain containing 1
chr6_-_111804905 0.153 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr11_-_65626797 0.147 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr10_+_75757863 0.145 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL


vinculin


chr2_-_96811170 0.144 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr11_+_86667117 0.144 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr12_-_62653903 0.142 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr1_+_6105974 0.133 ENST00000378083.3
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr10_-_29923893 0.132 ENST00000355867.4
SVIL
supervillin
chr2_-_208031943 0.132 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr3_-_123339343 0.131 ENST00000578202.1
MYLK
myosin light chain kinase
chr15_-_55581954 0.130 ENST00000336787.1
RAB27A
RAB27A, member RAS oncogene family
chr1_-_152332480 0.130 ENST00000388718.5
FLG2
filaggrin family member 2
chr9_-_35691017 0.129 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr17_-_55911970 0.128 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3

RP11-60A24.3

chr3_-_123339418 0.124 ENST00000583087.1
MYLK
myosin light chain kinase
chr11_-_65626753 0.123 ENST00000526975.1
ENST00000531413.1
CFL1

cofilin 1 (non-muscle)

chr17_-_27949911 0.114 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6


coronin 6


chr14_-_55369525 0.113 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1



GTP cyclohydrolase 1



chr19_+_16178317 0.112 ENST00000344824.6
ENST00000538887.1
TPM4

tropomyosin 4

chr5_+_137774706 0.110 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2


receptor accessory protein 2


chr8_-_143696833 0.109 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr5_+_66254698 0.108 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr19_+_45971246 0.108 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB





FBJ murine osteosarcoma viral oncogene homolog B





chr12_+_27932803 0.107 ENST00000381271.2
KLHL42
kelch-like family member 42
chr22_+_36784632 0.104 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr22_-_36784035 0.102 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chrX_-_11284095 0.100 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr11_-_71823266 0.100 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr3_+_99904531 0.099 ENST00000429523.2
ENST00000476804.1
TMEM30C

transmembrane protein 30C

chr1_-_91487770 0.098 ENST00000337393.5
ZNF644
zinc finger protein 644
chr4_-_109087872 0.097 ENST00000510624.1
LEF1
lymphoid enhancer-binding factor 1
chr6_-_105585022 0.097 ENST00000314641.5
BVES
blood vessel epicardial substance
chr1_+_113263199 0.096 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr17_-_10560619 0.095 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr10_+_31610064 0.093 ENST00000446923.2
ENST00000559476.1
ZEB1

zinc finger E-box binding homeobox 1

chr4_-_109087445 0.093 ENST00000512172.1
LEF1
lymphoid enhancer-binding factor 1
chr19_+_2476116 0.090 ENST00000215631.4
ENST00000587345.1
GADD45B

growth arrest and DNA-damage-inducible, beta

chr11_-_71823796 0.089 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15





anaphase promoting complex subunit 15





chr3_+_9834227 0.089 ENST00000287613.7
ENST00000397261.3
ARPC4

actin related protein 2/3 complex, subunit 4, 20kDa

chr3_+_9834179 0.088 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr1_-_91487806 0.087 ENST00000361321.5
ZNF644
zinc finger protein 644
chr10_+_88428370 0.087 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr1_-_229569834 0.086 ENST00000366684.3
ENST00000366683.2
ACTA1

actin, alpha 1, skeletal muscle

chr1_+_113263041 0.085 ENST00000369630.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr15_+_74218787 0.082 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr9_+_140772226 0.082 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
CACNA1B





calcium channel, voltage-dependent, N type, alpha 1B subunit





chr14_-_102553371 0.080 ENST00000553585.1
ENST00000216281.8
HSP90AA1

heat shock protein 90kDa alpha (cytosolic), class A member 1

chr17_-_41132088 0.079 ENST00000454303.1
ENST00000591916.1
ENST00000451885.2
PTGES3L-AARSD1
PTGES3L

PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 (cytosolic)-like

chr4_+_189321881 0.079 ENST00000512839.1
ENST00000513313.1
LINC01060

long intergenic non-protein coding RNA 1060

chr22_+_45714672 0.079 ENST00000424557.1
FAM118A
family with sequence similarity 118, member A
chr2_-_31030277 0.078 ENST00000534090.2
ENST00000295055.8
CAPN13

calpain 13

chr17_+_7487146 0.078 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1





mannose-P-dolichol utilization defect 1





chr5_-_53606396 0.075 ENST00000504924.1
ENST00000507646.2
ENST00000502271.1
ARL15


ADP-ribosylation factor-like 15


chr8_-_101965146 0.074 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta


chr4_-_109087906 0.073 ENST00000515500.1
LEF1
lymphoid enhancer-binding factor 1
chr2_+_87769459 0.073 ENST00000414030.1
ENST00000437561.1
LINC00152

long intergenic non-protein coding RNA 152

chr6_+_43139037 0.070 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr19_+_13135386 0.068 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX


nuclear factor I/X (CCAAT-binding transcription factor)


chr1_-_86043921 0.067 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_-_58295712 0.066 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_15104040 0.066 ENST00000541644.1
ENST00000545895.1
ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

chr14_+_74034310 0.066 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr17_+_30089454 0.065 ENST00000577970.1
RP11-805L22.3
RP11-805L22.3
chr8_-_37189432 0.064 ENST00000518765.1
RP11-527N22.1
RP11-527N22.1
chr19_+_13134772 0.064 ENST00000587760.1
ENST00000585575.1
NFIX

nuclear factor I/X (CCAAT-binding transcription factor)

chr16_+_4666475 0.063 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr18_+_54318566 0.062 ENST00000589935.1
ENST00000357574.3
WDR7

WD repeat domain 7

chr7_+_107531580 0.062 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD


dihydrolipoamide dehydrogenase


chr11_-_102323489 0.062 ENST00000361236.3
TMEM123
transmembrane protein 123
chr11_-_57282349 0.061 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr17_-_41132010 0.061 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1

PTGES3L-AARSD1 readthrough

chr7_-_5570229 0.060 ENST00000331789.5
ACTB
actin, beta
chr14_+_74706150 0.058 ENST00000261980.2
VSX2
visual system homeobox 2
chr20_+_4702548 0.057 ENST00000305817.2
PRND
prion protein 2 (dublet)
chr1_+_223889285 0.057 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr11_-_65667884 0.056 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr18_+_54318616 0.056 ENST00000254442.3
WDR7
WD repeat domain 7
chr3_+_9834758 0.055 ENST00000485273.1
ENST00000433034.1
ENST00000397256.1
ARPC4

ARPC4-TTLL3
actin related protein 2/3 complex, subunit 4, 20kDa

ARPC4-TTLL3 readthrough
chr3_-_9834375 0.052 ENST00000343450.2
ENST00000301964.2
TADA3

transcriptional adaptor 3

chr16_+_66413128 0.052 ENST00000563425.2
CDH5
cadherin 5, type 2 (vascular endothelium)
chr11_-_65667997 0.050 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr8_-_101965559 0.049 ENST00000353245.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_-_179050660 0.048 ENST00000519056.1
ENST00000506721.1
ENST00000503105.1
ENST00000504348.1
ENST00000508103.1
ENST00000510431.1
ENST00000515158.1
ENST00000393432.4
ENST00000442819.2
HNRNPH1








heterogeneous nuclear ribonucleoprotein H1 (H)








chr17_+_33474826 0.047 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B


unc-45 homolog B (C. elegans)


chr16_+_30077055 0.047 ENST00000564595.2
ENST00000569798.1
ALDOA

aldolase A, fructose-bisphosphate

chr16_+_30077098 0.047 ENST00000395240.3
ENST00000566846.1
ALDOA

aldolase A, fructose-bisphosphate

chr8_-_101965104 0.047 ENST00000437293.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr10_+_88428206 0.047 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr17_+_42634844 0.046 ENST00000315323.3
FZD2
frizzled family receptor 2
chr7_-_94285472 0.046 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE


sarcoglycan, epsilon


chr2_+_101179152 0.044 ENST00000264254.6
PDCL3
phosducin-like 3
chr3_-_9834463 0.044 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr3_+_63953415 0.043 ENST00000484332.1
ATXN7
ataxin 7
chr17_+_3379284 0.043 ENST00000263080.2
ASPA
aspartoacylase
chr8_-_101964832 0.042 ENST00000523131.1
ENST00000418997.1
YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

chr7_-_94285402 0.042 ENST00000428696.2
ENST00000445866.2
SGCE

sarcoglycan, epsilon

chr22_-_50216853 0.042 ENST00000342989.5
ENST00000542442.1
BRD1

bromodomain containing 1

chr11_+_34073195 0.041 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr11_-_71823715 0.041 ENST00000545944.1
ENST00000502597.2
ANAPC15

anaphase promoting complex subunit 15

chr7_-_94285511 0.041 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr10_-_16859361 0.040 ENST00000377921.3
RSU1
Ras suppressor protein 1
chr6_-_123957942 0.040 ENST00000398178.3
TRDN
triadin
chr8_-_101964738 0.039 ENST00000523938.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr14_+_75745477 0.038 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chr9_-_98269481 0.038 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1


patched 1


chr18_-_3220106 0.038 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr17_-_41132410 0.037 ENST00000409399.1
ENST00000421990.2
ENST00000409446.3
ENST00000453594.1
PTGES3L-AARSD1

PTGES3L

PTGES3L-AARSD1 readthrough

prostaglandin E synthase 3 (cytosolic)-like

chr5_-_169816638 0.037 ENST00000521859.1
ENST00000274629.4
KCNMB1

potassium large conductance calcium-activated channel, subfamily M, beta member 1

chr17_+_33474860 0.036 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr2_+_88367299 0.036 ENST00000419482.2
ENST00000444564.2
SMYD1

SET and MYND domain containing 1

chr6_-_88411911 0.035 ENST00000257787.5
AKIRIN2
akirin 2
chr6_-_123958141 0.035 ENST00000334268.4
TRDN
triadin
chr22_+_45714301 0.035 ENST00000427777.1
FAM118A
family with sequence similarity 118, member A
chr11_-_102323740 0.034 ENST00000398136.2
TMEM123
transmembrane protein 123
chr9_-_98269699 0.034 ENST00000429896.2
PTCH1
patched 1
chr10_-_16859442 0.030 ENST00000602389.1
ENST00000345264.5
RSU1

Ras suppressor protein 1

chr5_+_40679584 0.029 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr17_-_4890649 0.028 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr2_+_56179262 0.025 ENST00000606639.1
RP11-481J13.1
RP11-481J13.1
chr1_+_223889310 0.020 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr19_-_47975106 0.019 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2


solute carrier family 8 (sodium/calcium exchanger), member 2


chr7_+_112120908 0.017 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1


leucine-rich single-pass membrane protein 1


chr14_-_23877474 0.013 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr2_-_161056802 0.012 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr11_+_12108410 0.012 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr4_-_87028478 0.010 ENST00000515400.1
ENST00000395157.3
MAPK10

mitogen-activated protein kinase 10

chrX_-_103499602 0.010 ENST00000372588.4
ESX1
ESX homeobox 1
chr18_-_54318353 0.009 ENST00000590954.1
ENST00000540155.1
TXNL1

thioredoxin-like 1

chr17_+_41132564 0.009 ENST00000361677.1
ENST00000589705.1
RUNDC1

RUN domain containing 1

chr2_+_26915584 0.008 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr7_+_143078379 0.006 ENST00000449630.1
ENST00000457235.1
ZYX

zyxin

chr14_-_74226961 0.006 ENST00000286523.5
ENST00000435371.1
ELMSAN1

ELM2 and Myb/SANT-like domain containing 1

chr5_-_176923846 0.006 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chrX_-_153602991 0.005 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr20_-_62258394 0.004 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr15_+_96873921 0.002 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_+_53850991 0.001 ENST00000331251.3
NPBWR1
neuropeptides B/W receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.5 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 1.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.0 0.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 1.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.0 GO:0060022 membranous septum morphogenesis(GO:0003149) hard palate development(GO:0060022)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.9 GO:0032982 myosin filament(GO:0032982)
0.1 1.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.1 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation