Motif ID: SPIC

Z-value: 0.851


Transcription factors associated with SPIC:

Gene SymbolEntrez IDGene Name
SPIC ENSG00000166211.6 SPIC



Activity profile for motif SPIC.

activity profile for motif SPIC


Sorted Z-values histogram for motif SPIC

Sorted Z-values for motif SPIC



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIC

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46756351 1.637 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_121379739 1.471 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr9_-_130617029 0.953 ENST00000373203.4
ENG
endoglin
chr7_+_106505696 0.844 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr9_-_130616915 0.738 ENST00000344849.3
ENG
endoglin
chr15_-_88247083 0.685 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chrX_+_30233668 0.641 ENST00000378988.4
MAGEB2
melanoma antigen family B, 2
chr4_-_70653673 0.579 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr11_-_7698453 0.571 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr7_+_106505912 0.562 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr13_+_31309645 0.527 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr7_+_150382781 0.512 ENST00000223293.5
ENST00000474605.1
GIMAP2

GTPase, IMAP family member 2

chr5_+_174151536 0.491 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr14_+_63671105 0.445 ENST00000316754.3
RHOJ
ras homolog family member J
chr21_+_45773139 0.441 ENST00000397928.1
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr19_-_6481776 0.432 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C


DENN/MADD domain containing 1C


chr2_-_113594279 0.400 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr19_+_36346734 0.391 ENST00000586102.3
KIRREL2
kin of IRRE like 2 (Drosophila)
chr14_+_88471468 0.390 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr1_-_150738261 0.382 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr6_-_133079022 0.379 ENST00000525289.1
ENST00000326499.6
VNN2

vanin 2

chr19_+_51728316 0.377 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr7_-_143929936 0.370 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr6_-_169654139 0.358 ENST00000366787.3
THBS2
thrombospondin 2
chr16_+_71560154 0.352 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr12_+_54892550 0.351 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr16_+_71560023 0.337 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr19_-_6481759 0.332 ENST00000588421.1
DENND1C
DENN/MADD domain containing 1C
chr19_-_39826639 0.322 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr17_+_1959369 0.311 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr12_+_76653682 0.305 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr12_-_8693539 0.297 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr3_+_148583043 0.296 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr13_+_77522632 0.285 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr11_-_102668879 0.281 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr2_-_25451065 0.279 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr6_-_170151603 0.277 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr21_-_43786634 0.275 ENST00000291527.2
TFF1
trefoil factor 1
chr12_-_81331460 0.272 ENST00000549417.1
LIN7A
lin-7 homolog A (C. elegans)
chr5_-_137475071 0.272 ENST00000265191.2
NME5
NME/NM23 family member 5
chr15_-_80263506 0.272 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr6_-_11779174 0.270 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr6_-_11779403 0.270 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr22_-_37880543 0.270 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr15_-_90358048 0.266 ENST00000300060.6
ENST00000560137.1
ANPEP

alanyl (membrane) aminopeptidase

chr10_-_98480243 0.264 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr17_-_56406117 0.261 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr8_-_16050288 0.257 ENST00000350896.3
MSR1
macrophage scavenger receptor 1
chr12_-_18243119 0.255 ENST00000538724.1
ENST00000229002.2
RERGL

RERG/RAS-like

chr12_+_54891495 0.252 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr2_-_205099700 0.249 ENST00000419860.1
AC009498.1
AC009498.1
chr6_-_11779840 0.248 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr6_-_11779014 0.248 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr12_+_6933660 0.248 ENST00000545321.1
GPR162
G protein-coupled receptor 162
chr18_-_53253112 0.246 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr6_+_139349903 0.245 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr6_+_159084188 0.240 ENST00000367081.3
SYTL3
synaptotagmin-like 3
chr8_+_85097110 0.240 ENST00000517638.1
ENST00000522647.1
RALYL

RALY RNA binding protein-like

chr21_-_15918618 0.235 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr11_-_75236867 0.234 ENST00000376282.3
ENST00000336898.3
GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

chr7_-_75443118 0.230 ENST00000222902.2
CCL24
chemokine (C-C motif) ligand 24
chr11_+_7618413 0.226 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_-_16050214 0.221 ENST00000262101.5
MSR1
macrophage scavenger receptor 1
chr21_+_47063590 0.219 ENST00000400314.1
PCBP3
poly(rC) binding protein 3
chr12_+_76653611 0.216 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr21_+_17566643 0.214 ENST00000419952.1
ENST00000445461.2
LINC00478

long intergenic non-protein coding RNA 478

chr1_-_31230650 0.214 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr10_-_121302195 0.212 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr10_+_102106829 0.204 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr3_+_52321827 0.203 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK




glycerate kinase




chr6_-_32191834 0.202 ENST00000375023.3
NOTCH4
notch 4
chr1_+_111415757 0.200 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chr18_-_53253323 0.193 ENST00000540999.1
ENST00000563888.2
TCF4

transcription factor 4

chr12_-_120907374 0.192 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr16_-_88717482 0.188 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr2_+_233925064 0.188 ENST00000359570.5
ENST00000538935.1
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr16_+_30194916 0.188 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A


coronin, actin binding protein, 1A


chr20_+_1875110 0.185 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr11_+_7626950 0.180 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_+_48866448 0.177 ENST00000266594.1
ANP32D
acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
chr4_-_54518619 0.177 ENST00000507168.1
ENST00000510143.1
LNX1

ligand of numb-protein X 1, E3 ubiquitin protein ligase

chr6_+_159071015 0.176 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr1_-_204183071 0.173 ENST00000308302.3
GOLT1A
golgi transport 1A
chr1_+_161677034 0.170 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA




Fc receptor-like A




chr3_+_124303539 0.169 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr1_+_149230680 0.168 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr12_+_120105558 0.166 ENST00000229328.5
ENST00000541640.1
PRKAB1

protein kinase, AMP-activated, beta 1 non-catalytic subunit

chr16_+_29465822 0.166 ENST00000330181.5
ENST00000351581.4
SLX1B

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr8_-_59412717 0.163 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr12_-_371994 0.162 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13



solute carrier family 6 (neurotransmitter transporter), member 13



chr19_+_56813305 0.162 ENST00000593151.1
AC006116.20
Uncharacterized protein
chr3_+_124303512 0.161 ENST00000454902.1
KALRN
kalirin, RhoGEF kinase
chr1_-_32210275 0.158 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr15_-_75918500 0.156 ENST00000569817.1
SNUPN
snurportin 1
chr8_-_133637624 0.154 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr3_-_111314230 0.154 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr12_+_54447637 0.153 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr2_+_120187465 0.153 ENST00000409826.1
ENST00000417645.1
TMEM37

transmembrane protein 37

chr5_-_43313269 0.152 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_-_238323007 0.151 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr16_+_30205225 0.151 ENST00000345535.4
ENST00000251303.6
SLX1A

SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

chr1_-_231005310 0.150 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr16_+_78133293 0.150 ENST00000566780.1
WWOX
WW domain containing oxidoreductase
chrX_+_133941218 0.148 ENST00000370784.4
ENST00000370785.3
FAM122C

family with sequence similarity 122C

chr2_-_64751227 0.148 ENST00000561559.1
RP11-568N6.1
RP11-568N6.1
chr16_+_80574854 0.146 ENST00000305904.6
ENST00000568035.1
DYNLRB2

dynein, light chain, roadblock-type 2

chr21_-_46340807 0.144 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
ITGB2


integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)


chr1_+_116519112 0.143 ENST00000369503.4
SLC22A15
solute carrier family 22, member 15
chr12_+_105724613 0.142 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr6_+_116691001 0.141 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr14_-_69446034 0.140 ENST00000193403.6
ACTN1
actinin, alpha 1
chr19_-_50400212 0.140 ENST00000391826.2
IL4I1
interleukin 4 induced 1
chr12_+_120884222 0.140 ENST00000551765.1
ENST00000229384.5
GATC

glutamyl-tRNA(Gln) amidotransferase, subunit C

chr11_-_7961141 0.140 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr12_-_120907459 0.138 ENST00000229390.3
SRSF9
serine/arginine-rich splicing factor 9
chr12_-_8218997 0.138 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr6_+_170863421 0.137 ENST00000392092.2
ENST00000540980.1
ENST00000230354.6
TBP


TATA box binding protein


chr16_+_82068585 0.137 ENST00000563491.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr12_+_105724414 0.137 ENST00000443585.1
ENST00000552457.1
ENST00000549893.1
C12orf75


chromosome 12 open reading frame 75


chr14_-_69445968 0.137 ENST00000438964.2
ACTN1
actinin, alpha 1
chr22_+_31523734 0.136 ENST00000402238.1
ENST00000404453.1
ENST00000401755.1
INPP5J


inositol polyphosphate-5-phosphatase J


chr17_+_7487146 0.136 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1





mannose-P-dolichol utilization defect 1





chr3_-_156272872 0.135 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr3_+_124303472 0.134 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr12_-_110888103 0.133 ENST00000426440.1
ENST00000228825.7
ARPC3

actin related protein 2/3 complex, subunit 3, 21kDa

chr5_-_53115506 0.133 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1

CTD-2081C10.1

chr3_+_32433363 0.131 ENST00000465248.1
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr6_+_170615819 0.131 ENST00000476287.1
ENST00000252510.9
FAM120B

family with sequence similarity 120B

chr3_-_156272924 0.129 ENST00000467789.1
ENST00000265044.2
SSR3

signal sequence receptor, gamma (translocon-associated protein gamma)

chr3_-_17783990 0.127 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5







TBC1 domain family, member 5







chr3_+_101659682 0.127 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr14_-_69445793 0.126 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr3_-_52322019 0.126 ENST00000463624.1
WDR82
WD repeat domain 82
chr12_-_120663792 0.125 ENST00000546532.1
ENST00000548912.1
PXN

paxillin

chr12_-_18243075 0.125 ENST00000536890.1
RERGL
RERG/RAS-like
chr16_-_88717423 0.125 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA


cytochrome b-245, alpha polypeptide


chr3_-_123512688 0.125 ENST00000475616.1
MYLK
myosin light chain kinase
chr11_+_133938820 0.123 ENST00000299106.4
ENST00000529443.2
JAM3

junctional adhesion molecule 3

chr16_+_82068873 0.123 ENST00000566213.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr15_-_89089860 0.123 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1


de-etiolated homolog 1 (Arabidopsis)


chr5_-_107052398 0.122 ENST00000509458.1
RP11-252I13.2
RP11-252I13.2
chr3_+_149530836 0.120 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
RNF13


ring finger protein 13


chr6_+_170863353 0.119 ENST00000421512.1
TBP
TATA box binding protein
chr5_+_145718587 0.119 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr17_-_34417479 0.115 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr3_+_16926441 0.115 ENST00000418129.2
ENST00000396755.2
PLCL2

phospholipase C-like 2

chr1_+_210612925 0.115 ENST00000367009.1
HHAT
hedgehog acyltransferase
chr12_-_121019165 0.114 ENST00000341039.2
ENST00000357500.4
POP5

processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)

chr3_+_150264458 0.114 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr22_+_37257015 0.113 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
NCF4


neutrophil cytosolic factor 4, 40kDa


chr21_-_46340770 0.113 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_-_74489215 0.113 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2


rhomboid 5 homolog 2 (Drosophila)


chr4_+_74606223 0.112 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr16_+_78133536 0.112 ENST00000402655.2
ENST00000406884.2
ENST00000539474.2
ENST00000569818.1
ENST00000355860.3
ENST00000408984.3
WWOX





WW domain containing oxidoreductase





chr3_+_132136331 0.111 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr3_+_130613001 0.110 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr15_-_64455404 0.108 ENST00000300026.3
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr21_-_46340884 0.108 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr6_+_116601265 0.107 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr3_+_142720366 0.107 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP



U2 snRNP-associated SURP domain containing



chr10_-_75401500 0.107 ENST00000359322.4
MYOZ1
myozenin 1
chr2_+_63277927 0.106 ENST00000282549.2
OTX1
orthodenticle homeobox 1
chr4_-_110723134 0.106 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr17_+_72211755 0.106 ENST00000529107.1
TTYH2
tweety family member 2
chr19_-_50400125 0.105 ENST00000593956.1
IL4I1
interleukin 4 induced 1
chr6_-_170862322 0.105 ENST00000262193.6
PSMB1
proteasome (prosome, macropain) subunit, beta type, 1
chr3_+_150264555 0.105 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr6_+_12290586 0.104 ENST00000379375.5
EDN1
endothelin 1
chr12_-_8218926 0.104 ENST00000546241.1
C3AR1
complement component 3a receptor 1
chr9_+_5510492 0.104 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chrX_+_70503433 0.104 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO



non-POU domain containing, octamer-binding



chr15_-_90233907 0.104 ENST00000561224.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr2_+_64751433 0.104 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH


aftiphilin


chr8_+_11351494 0.103 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr3_+_130612803 0.103 ENST00000510168.1
ENST00000508532.1
ATP2C1

ATPase, Ca++ transporting, type 2C, member 1

chr1_+_161676739 0.101 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA






Fc receptor-like A






chr2_-_99485825 0.100 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr15_-_67546963 0.100 ENST00000561452.1
ENST00000261880.5
AAGAB

alpha- and gamma-adaptin binding protein

chr15_-_75918109 0.099 ENST00000567134.1
ENST00000308588.5
SNUPN

snurportin 1

chr1_-_246729544 0.099 ENST00000544618.1
ENST00000366514.4
TFB2M

transcription factor B2, mitochondrial

chr16_+_3313791 0.098 ENST00000538765.1
ZNF263
zinc finger protein 263
chr3_+_130613226 0.097 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1




ATPase, Ca++ transporting, type 2C, member 1




chr8_-_80942467 0.097 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28


mitochondrial ribosomal protein S28


chr17_+_68047418 0.097 ENST00000586373.1
ENST00000588782.1
LINC01028

long intergenic non-protein coding RNA 1028

chr11_+_94706804 0.097 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr1_-_154946792 0.096 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr3_-_16554881 0.096 ENST00000451036.1
RFTN1
raftlin, lipid raft linker 1
chr16_-_88851618 0.095 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr12_-_15114658 0.095 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_91296602 0.094 ENST00000369325.3
ENST00000369327.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr12_-_7596735 0.094 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1


CD163 molecule-like 1


chr6_-_91296737 0.094 ENST00000369332.3
ENST00000369329.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr12_-_120884175 0.094 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chrX_+_24072833 0.094 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr21_+_40181520 0.094 ENST00000456966.1
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr12_-_15114603 0.094 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr15_-_75918023 0.093 ENST00000564644.1
ENST00000371091.5
ENST00000564675.1
SNUPN


snurportin 1


chr3_+_48481658 0.093 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr17_+_7835419 0.093 ENST00000576538.1
ENST00000380262.3
ENST00000563694.1
ENST00000380255.3
ENST00000570782.1
CNTROB




centrobin, centrosomal BRCA2 interacting protein




chr3_-_154042235 0.092 ENST00000308361.6
ENST00000496811.1
ENST00000544526.1
DHX36


DEAH (Asp-Glu-Ala-His) box polypeptide 36



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 0.5 GO:0090427 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.4 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 1.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.7 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 2.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.5 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) catagen(GO:0042637) regulation of catagen(GO:0051794) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.4 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404)
0.0 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.8 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886) negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:1903722 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:1901076 regulation of engulfment of apoptotic cell(GO:1901074) positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0010266 response to vitamin B1(GO:0010266)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.0 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.0 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.3 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:2000416 regulation of eosinophil migration(GO:2000416)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0072563 endothelial microparticle(GO:0072563)
0.4 1.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.4 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0097550 male pronucleus(GO:0001940) transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.4 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0001042 RNA polymerase I core binding(GO:0001042) RNA polymerase core enzyme binding(GO:0043175)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID_IL27_PATHWAY IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols