Motif ID: SOX7

Z-value: 0.241


Transcription factors associated with SOX7:

Gene SymbolEntrez IDGene Name
SOX7 ENSG00000171056.6 SOX7
SOX7 ENSG00000258724.1 SOX7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10697281_106973650.908.3e-04Click!


Activity profile for motif SOX7.

activity profile for motif SOX7


Sorted Z-values histogram for motif SOX7

Sorted Z-values for motif SOX7



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_5005445 0.429 ENST00000380872.4
 AKR1C1
aldo-keto reductase family 1, member C1
chr10_-_5046042 0.295 ENST00000421196.3
ENST00000455190.1
 AKR1C2

aldo-keto reductase family 1, member C2

chr10_-_5652705 0.208 ENST00000425246.1
 RP11-336A10.5
RP11-336A10.5
chr10_-_61495760 0.178 ENST00000395347.1
 SLC16A9
solute carrier family 16, member 9
chr5_-_95158644 0.141 ENST00000237858.6
 GLRX
glutaredoxin (thioltransferase)
chr2_-_190445499 0.140 ENST00000261024.2
 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr8_-_19459993 0.126 ENST00000454498.2
ENST00000520003.1
 CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr5_-_95158375 0.125 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX



glutaredoxin (thioltransferase)



chr10_+_24738355 0.114 ENST00000307544.6
 KIAA1217
KIAA1217
chr4_+_75174180 0.113 ENST00000413830.1
 EPGN
epithelial mitogen
chr1_+_10509971 0.108 ENST00000320498.4
 CORT
cortistatin
chr1_+_11724167 0.084 ENST00000376753.4
 FBXO6
F-box protein 6
chr6_+_168434678 0.077 ENST00000496008.1
 KIF25
kinesin family member 25
chr4_-_39034542 0.076 ENST00000344606.6
 TMEM156
transmembrane protein 156
chr18_+_32820990 0.065 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
 ZNF397





zinc finger protein 397





chr12_-_90049878 0.058 ENST00000359142.3
 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_-_152118276 0.056 ENST00000409092.1
 RBM43
RNA binding motif protein 43
chr12_-_90049828 0.055 ENST00000261173.2
ENST00000348959.3
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr12_-_39734783 0.052 ENST00000552961.1
 KIF21A
kinesin family member 21A
chr3_-_161089289 0.043 ENST00000497137.1
 SPTSSB
serine palmitoyltransferase, small subunit B
chr14_-_102771462 0.036 ENST00000522874.1
 MOK
MOK protein kinase
chr4_+_69313145 0.032 ENST00000305363.4
 TMPRSS11E
transmembrane protease, serine 11E
chr6_+_42531798 0.032 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
 UBR2


ubiquitin protein ligase E3 component n-recognin 2


chr11_+_3011093 0.032 ENST00000332881.2
 AC131971.1
HCG1782999; PRO0943; Uncharacterized protein
chr6_+_29555683 0.030 ENST00000383640.2
 OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr2_-_166930131 0.030 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr5_-_176778803 0.030 ENST00000303127.7
 LMAN2
lectin, mannose-binding 2
chr1_-_26394114 0.029 ENST00000374272.3
 TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr4_-_4544061 0.029 ENST00000507908.1
 STX18
syntaxin 18
chr1_-_186430222 0.029 ENST00000391997.2
 PDC
phosducin
chr19_-_38916839 0.029 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
 RASGRP4




RAS guanyl releasing protein 4




chr3_+_107318157 0.028 ENST00000406780.1
 BBX
bobby sox homolog (Drosophila)
chr15_+_63414760 0.027 ENST00000557972.1
 LACTB
lactamase, beta
chr14_-_31856397 0.026 ENST00000538864.2
ENST00000550366.1
 HEATR5A

HEAT repeat containing 5A

chr16_+_22518495 0.024 ENST00000541154.1
 NPIPB5
nuclear pore complex interacting protein family, member B5
chr7_-_33148975 0.023 ENST00000297157.3
 RP9
retinitis pigmentosa 9 (autosomal dominant)
chr19_-_22379753 0.022 ENST00000397121.2
 ZNF676
zinc finger protein 676
chr19_-_38916822 0.022 ENST00000586305.1
 RASGRP4
RAS guanyl releasing protein 4
chr4_-_47983519 0.022 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr12_-_56693758 0.021 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
 CS



citrate synthase



chr10_-_96829246 0.021 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
 CYP2C8


cytochrome P450, family 2, subfamily C, polypeptide 8


chr16_-_21442874 0.021 ENST00000534903.1
 NPIPB3
nuclear pore complex interacting protein family, member B3
chr2_+_179317994 0.020 ENST00000375129.4
 DFNB59
deafness, autosomal recessive 59
chr8_+_12803176 0.017 ENST00000524591.2
 KIAA1456
KIAA1456
chr14_+_50291993 0.014 ENST00000595378.1
 AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr4_-_177190364 0.013 ENST00000296525.3
 ASB5
ankyrin repeat and SOCS box containing 5
chr14_+_60712463 0.013 ENST00000325642.3
ENST00000529574.1
 PPM1A

protein phosphatase, Mg2+/Mn2+ dependent, 1A

chr11_-_62474803 0.012 ENST00000533982.1
ENST00000360796.5
 BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr17_-_65235916 0.012 ENST00000579861.1
 HELZ
helicase with zinc finger
chr17_-_56082455 0.010 ENST00000578794.1
 RP11-159D12.5
Uncharacterized protein
chr10_+_96162242 0.010 ENST00000225235.4
 TBC1D12
TBC1 domain family, member 12
chr10_-_12084770 0.009 ENST00000357604.5
 UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr5_+_175511859 0.007 ENST00000503724.2
ENST00000253490.4
 FAM153B

family with sequence similarity 153, member B

chr1_+_199996733 0.004 ENST00000236914.3
 NR5A2
nuclear receptor subfamily 5, group A, member 2
chr1_+_156698708 0.004 ENST00000519086.1
 RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr6_+_150690028 0.004 ENST00000229447.5
ENST00000344419.3
 IYD

iodotyrosine deiodinase

chr12_-_123728548 0.003 ENST00000545406.1
 MPHOSPH9
M-phase phosphoprotein 9
chr12_-_57443886 0.002 ENST00000300119.3
 MYO1A
myosin IA
chr19_+_37837185 0.002 ENST00000541583.2
 HKR1
HKR1, GLI-Kruppel zinc finger family member

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)