Motif ID: SOX5

Z-value: 0.614


Transcription factors associated with SOX5:

Gene SymbolEntrez IDGene Name
SOX5 ENSG00000134532.11 SOX5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX5hg19_v2_chr12_-_24102576_24102637-0.933.5e-04Click!


Activity profile for motif SOX5.

activity profile for motif SOX5


Sorted Z-values histogram for motif SOX5

Sorted Z-values for motif SOX5



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46716969 1.017 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_25469802 0.864 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr3_+_25469724 0.840 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr8_+_85095497 0.821 ENST00000522455.1
ENST00000521695.1
RALYL

RALY RNA binding protein-like

chr11_+_131781290 0.621 ENST00000425719.2
ENST00000374784.1
NTM

neurotrimin

chr8_+_85095769 0.614 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chrX_-_142722897 0.540 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr10_-_62149433 0.494 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_-_111358372 0.488 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr9_-_72287191 0.479 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr17_-_46671323 0.467 ENST00000239151.5
HOXB5
homeobox B5
chr6_+_13182751 0.460 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr4_-_186732048 0.451 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr3_-_46904946 0.434 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr6_-_138893661 0.434 ENST00000427025.2
NHSL1
NHS-like 1
chr10_-_62332357 0.431 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_-_134861089 0.425 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chrX_+_135251783 0.380 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr3_-_46904918 0.378 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr4_-_186732892 0.373 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chrX_-_112084043 0.371 ENST00000304758.1
AMOT
angiomotin
chr11_-_115375107 0.366 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chrX_+_24483338 0.364 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr1_+_209757051 0.362 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
CAMK1G


calcium/calmodulin-dependent protein kinase IG


chrX_+_135252050 0.359 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr9_+_82188077 0.359 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_-_111846435 0.356 ENST00000437633.1
ENST00000428084.1
DOCK4

dedicator of cytokinesis 4

chrX_+_135251835 0.343 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr12_-_71003568 0.342 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB




protein tyrosine phosphatase, receptor type, B




chr6_-_13290684 0.342 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr3_-_8686479 0.329 ENST00000544814.1
ENST00000427408.1
SSUH2

ssu-2 homolog (C. elegans)

chr3_-_55521323 0.322 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr12_-_71031185 0.292 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr13_+_110958124 0.288 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr8_+_85095553 0.287 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr15_+_90319557 0.274 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr3_-_99595037 0.269 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr7_-_111424462 0.269 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr7_-_111424506 0.268 ENST00000450156.1
ENST00000494651.2
DOCK4

dedicator of cytokinesis 4

chr1_-_40367668 0.263 ENST00000397332.2
ENST00000429311.1
MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chr9_+_129097520 0.263 ENST00000436593.3
MVB12B
multivesicular body subunit 12B
chr3_-_99594948 0.260 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr17_+_1666108 0.259 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_52445191 0.257 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr15_+_49715449 0.251 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr3_-_52486841 0.249 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr1_-_156217829 0.245 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
PAQR6



progestin and adipoQ receptor family member VI



chr12_-_71031220 0.244 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr7_+_134551583 0.244 ENST00000435928.1
CALD1
caldesmon 1
chr18_-_53177984 0.237 ENST00000543082.1
TCF4
transcription factor 4
chr7_+_28452130 0.231 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr4_-_186732241 0.224 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_156217822 0.224 ENST00000368270.1
PAQR6
progestin and adipoQ receptor family member VI
chr1_-_156217875 0.223 ENST00000292291.5
PAQR6
progestin and adipoQ receptor family member VI
chr3_-_192635943 0.223 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr19_-_7698599 0.219 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr10_+_99079008 0.215 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr18_-_52989217 0.214 ENST00000570287.2
TCF4
transcription factor 4
chr12_-_121973974 0.209 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B


lysine (K)-specific demethylase 2B


chr2_-_208030295 0.209 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_+_129097479 0.208 ENST00000402437.2
MVB12B
multivesicular body subunit 12B
chr2_-_70475730 0.207 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1


TIA1 cytotoxic granule-associated RNA binding protein


chr2_+_220495800 0.206 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr3_-_57233966 0.205 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr3_+_189507523 0.203 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr15_+_57211318 0.201 ENST00000557947.1
TCF12
transcription factor 12
chr15_-_86338100 0.200 ENST00000536947.1
KLHL25
kelch-like family member 25
chr2_-_70475701 0.200 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr12_+_9066472 0.198 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr2_-_70475586 0.197 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr15_-_86338134 0.196 ENST00000337975.5
KLHL25
kelch-like family member 25
chr1_-_40367530 0.191 ENST00000372816.2
ENST00000372815.1
MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chr6_-_139613269 0.188 ENST00000358430.3
TXLNB
taxilin beta
chr14_+_37126765 0.188 ENST00000402703.2
PAX9
paired box 9
chr3_+_189507432 0.185 ENST00000354600.5
TP63
tumor protein p63
chr2_-_208030647 0.183 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr15_+_71228826 0.183 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr3_+_189349162 0.182 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63





chr5_-_146461027 0.177 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chrX_-_50557302 0.176 ENST00000289292.7
SHROOM4
shroom family member 4
chrX_-_50557014 0.176 ENST00000376020.2
SHROOM4
shroom family member 4
chr10_-_118897567 0.164 ENST00000369206.5
VAX1
ventral anterior homeobox 1
chr5_-_176836577 0.161 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr6_+_12290586 0.159 ENST00000379375.5
EDN1
endothelin 1
chr20_-_45985172 0.156 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr13_+_28813645 0.150 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr15_+_91416092 0.148 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_+_41236325 0.145 ENST00000426215.1
ENST00000405570.1
CTNNB1

catenin (cadherin-associated protein), beta 1, 88kDa

chr11_+_111808119 0.145 ENST00000531396.1
DIXDC1
DIX domain containing 1
chr6_-_152957988 0.142 ENST00000367248.3
SYNE1
spectrin repeat containing, nuclear envelope 1
chr7_+_134576151 0.142 ENST00000393118.2
CALD1
caldesmon 1
chr1_-_226926864 0.141 ENST00000429204.1
ENST00000366784.1
ITPKB

inositol-trisphosphate 3-kinase B

chr2_-_208030886 0.139 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_-_73360796 0.138 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3


D4, zinc and double PHD fingers, family 3


chr2_-_25451065 0.137 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr2_+_86668464 0.136 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr18_-_52989525 0.136 ENST00000457482.3
TCF4
transcription factor 4
chr10_-_99094458 0.135 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr7_+_134576317 0.134 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr7_-_83824169 0.132 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_+_42260861 0.131 ENST00000282030.5
SETBP1
SET binding protein 1
chr19_+_55888186 0.131 ENST00000291934.3
TMEM190
transmembrane protein 190
chr1_+_147013182 0.129 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr9_-_126030817 0.129 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP


spermatid perinuclear RNA binding protein


chr17_-_46703826 0.128 ENST00000550387.1
ENST00000311177.5
HOXB9

homeobox B9

chr9_-_128246769 0.127 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr12_-_102591604 0.124 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr7_-_83824449 0.124 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_116673894 0.123 ENST00000395713.2
TRPS1
trichorhinophalangeal syndrome I
chr3_+_112930306 0.123 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr5_+_91378410 0.122 ENST00000507217.1
RP11-348J24.2
RP11-348J24.2
chr13_+_103459704 0.122 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr3_-_123339343 0.122 ENST00000578202.1
MYLK
myosin light chain kinase
chr9_+_132099158 0.120 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chrX_+_70503037 0.119 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr15_+_75074385 0.118 ENST00000220003.9
CSK
c-src tyrosine kinase
chr1_-_8000872 0.117 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_-_133427767 0.117 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr1_-_48227290 0.117 ENST00000594280.1
FLJ00388
FLJ00388
chr3_-_123339418 0.116 ENST00000583087.1
MYLK
myosin light chain kinase
chrX_+_70503433 0.113 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO



non-POU domain containing, octamer-binding



chr12_-_96793142 0.113 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17


cyclin-dependent kinase 17


chr15_+_75074410 0.112 ENST00000439220.2
CSK
c-src tyrosine kinase
chr3_-_71632894 0.112 ENST00000493089.1
FOXP1
forkhead box P1
chr2_-_86422523 0.110 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT


inner membrane protein, mitochondrial


chr10_-_32667660 0.110 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_50889155 0.109 ENST00000404795.3
DMRTA2
DMRT-like family A2
chr11_+_111807863 0.109 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr6_+_155538093 0.105 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr20_-_45985414 0.103 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
ZMYND8








zinc finger, MYND-type containing 8








chr11_-_72852958 0.102 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr3_-_71353892 0.101 ENST00000484350.1
FOXP1
forkhead box P1
chr6_+_88054530 0.100 ENST00000388923.4
C6orf163
chromosome 6 open reading frame 163
chr9_-_98268883 0.099 ENST00000551630.1
ENST00000548420.1
PTCH1

patched 1

chr20_-_45985464 0.099 ENST00000458360.2
ENST00000262975.4
ZMYND8

zinc finger, MYND-type containing 8

chr6_+_155537771 0.098 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr16_+_53469525 0.098 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr9_-_15510989 0.098 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1



PC4 and SFRS1 interacting protein 1



chr6_+_21666633 0.098 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr11_-_79151695 0.097 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr12_+_78224667 0.097 ENST00000549464.1
NAV3
neuron navigator 3
chr10_+_35415719 0.096 ENST00000474362.1
ENST00000374721.3
CREM

cAMP responsive element modulator

chr12_-_6233828 0.096 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr3_-_114790179 0.095 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_122985067 0.094 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr12_-_12674032 0.093 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr3_-_114343039 0.091 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_122985494 0.090 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr11_-_115127611 0.089 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr1_-_243349684 0.089 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr14_+_77228532 0.088 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr1_+_156589051 0.087 ENST00000255039.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr5_-_131879205 0.087 ENST00000231454.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr17_+_33448593 0.086 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr14_-_92414055 0.085 ENST00000342058.4
FBLN5
fibulin 5
chr3_-_11685345 0.084 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr20_-_45981138 0.084 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr9_-_134145880 0.083 ENST00000372269.3
ENST00000464831.1
FAM78A

family with sequence similarity 78, member A

chr3_+_141106643 0.083 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_-_16505440 0.082 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr11_+_112832202 0.082 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr12_+_78359999 0.081 ENST00000550503.1
NAV3
neuron navigator 3
chr18_-_48723690 0.081 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr1_+_109265033 0.080 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr6_-_99873145 0.079 ENST00000369239.5
ENST00000438806.1
PNISR

PNN-interacting serine/arginine-rich protein

chr12_+_50479109 0.079 ENST00000550477.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr12_+_50478977 0.077 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr10_+_97803151 0.077 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ



cyclin J



chr3_-_114173654 0.075 ENST00000482689.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_30960915 0.075 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1


aquaporin 1 (Colton blood group)


chr3_+_120315160 0.074 ENST00000485064.1
ENST00000492739.1
NDUFB4

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa

chr4_-_101439148 0.074 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN


endomucin


chr5_-_39462390 0.072 ENST00000511792.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_+_50479101 0.072 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr13_+_73629107 0.072 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr6_+_89790490 0.071 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr11_+_36397915 0.070 ENST00000526682.1
ENST00000530252.1
PRR5L

proline rich 5 like

chr20_-_45984401 0.069 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr3_+_141106458 0.069 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr3_+_120315149 0.069 ENST00000184266.2
NDUFB4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr6_+_89790459 0.068 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr10_+_35415978 0.068 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM


cAMP responsive element modulator


chr12_-_498415 0.068 ENST00000535014.1
ENST00000543507.1
ENST00000544760.1
KDM5A


lysine (K)-specific demethylase 5A


chrX_+_15525426 0.068 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr2_-_97536490 0.067 ENST00000449330.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr18_+_21594384 0.066 ENST00000584250.1
TTC39C
tetratricopeptide repeat domain 39C
chr3_-_19988462 0.065 ENST00000344838.4
EFHB
EF-hand domain family, member B
chrX_+_123094369 0.065 ENST00000455404.1
ENST00000218089.9
STAG2

stromal antigen 2

chr1_+_33722080 0.065 ENST00000483388.1
ENST00000539719.1
ZNF362

zinc finger protein 362

chr6_+_122720681 0.065 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr3_+_112930387 0.064 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr6_-_128222103 0.064 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS


thymocyte selection associated


chr13_-_84456527 0.064 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr9_+_27109133 0.064 ENST00000519097.1
ENST00000380036.4
TEK

TEK tyrosine kinase, endothelial

chrX_+_78003204 0.064 ENST00000435339.3
ENST00000514744.1
LPAR4

lysophosphatidic acid receptor 4

chrX_+_123094672 0.063 ENST00000354548.5
ENST00000458700.1
STAG2

stromal antigen 2

chr1_-_243418621 0.062 ENST00000366544.1
ENST00000366543.1
CEP170

centrosomal protein 170kDa

chr17_-_41910505 0.062 ENST00000398389.4
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr11_+_19799327 0.062 ENST00000540292.1
NAV2
neuron navigator 2
chr1_-_243418344 0.062 ENST00000366542.1
CEP170
centrosomal protein 170kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.2 0.9 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.5 GO:0019075 virus maturation(GO:0019075)
0.1 0.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 1.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.9 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 1.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.3 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection