Motif ID: SOX3_SOX2

Z-value: 0.672

Transcription factors associated with SOX3_SOX2:

Gene SymbolEntrez IDGene Name
SOX2 ENSG00000181449.2 SOX2
SOX3 ENSG00000134595.6 SOX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX2hg19_v2_chr3_+_181429704_1814297220.373.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of SOX3_SOX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_45270077 0.375 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr12_-_58145889 0.353 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr14_-_60097297 0.294 ENST00000395090.1
RTN1
reticulon 1
chr12_-_45270151 0.294 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr8_+_61822605 0.290 ENST00000526936.1
AC022182.1
AC022182.1
chr5_+_173930676 0.259 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr5_+_15500280 0.253 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr5_-_146833803 0.242 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr2_-_158182322 0.240 ENST00000420719.2
ENST00000409216.1
ERMN

ermin, ERM-like protein

chr8_-_20161466 0.228 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr4_+_26322987 0.226 ENST00000505958.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_146833485 0.221 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr12_-_45307711 0.208 ENST00000333837.4
ENST00000551949.1
NELL2

NEL-like 2 (chicken)

chr1_+_59522284 0.207 ENST00000449812.2
RP11-145M4.3
RP11-145M4.3
chr12_-_45269769 0.198 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr2_-_158182105 0.197 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr15_-_67439270 0.182 ENST00000558463.1
RP11-342M21.2
Uncharacterized protein
chrX_-_139866723 0.182 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr5_+_173930710 0.179 ENST00000511707.1
RP11-267A15.1
RP11-267A15.1
chr5_-_149792295 0.177 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr9_-_117160738 0.173 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chr19_+_1452188 0.173 ENST00000587149.1
APC2
adenomatosis polyposis coli 2
chr14_-_60097524 0.171 ENST00000342503.4
RTN1
reticulon 1
chr16_-_80926457 0.166 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1

RP11-314O13.1

chr12_-_24103841 0.161 ENST00000541847.1
SOX5
SRY (sex determining region Y)-box 5
chr9_-_117420052 0.161 ENST00000423632.1
RP11-402G3.5
RP11-402G3.5
chr17_+_72428218 0.159 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr12_-_24103954 0.159 ENST00000441133.2
ENST00000545921.1
SOX5

SRY (sex determining region Y)-box 5

chr17_+_72427477 0.151 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr8_-_17579726 0.150 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr2_-_165424973 0.149 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr20_-_39317868 0.147 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr10_-_21806759 0.147 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr14_-_80678512 0.146 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr5_-_157079428 0.143 ENST00000265007.6
SOX30
SRY (sex determining region Y)-box 30
chr11_+_34654011 0.143 ENST00000531794.1
EHF
ets homologous factor
chr7_+_73703728 0.141 ENST00000361545.5
ENST00000223398.6
CLIP2

CAP-GLY domain containing linker protein 2

chr5_+_140593509 0.135 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr11_-_94965667 0.135 ENST00000542176.1
ENST00000278499.2
SESN3

sestrin 3

chrX_-_43832711 0.134 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr2_+_17721230 0.133 ENST00000457525.1
VSNL1
visinin-like 1
chr10_-_24770632 0.132 ENST00000596413.1
AL353583.1
AL353583.1
chr8_+_19759228 0.131 ENST00000520959.1
LPL
lipoprotein lipase
chr3_+_3841108 0.128 ENST00000319331.3
LRRN1
leucine rich repeat neuronal 1
chr14_-_91884150 0.128 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr12_-_8803128 0.128 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr2_+_176964458 0.126 ENST00000406506.2
ENST00000404162.2
HOXD12

homeobox D12

chr13_+_36920569 0.126 ENST00000379848.2
SPG20OS
SPG20 opposite strand
chr5_-_141338377 0.126 ENST00000510041.1
PCDH12
protocadherin 12
chr3_-_167813672 0.124 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr7_-_127671674 0.123 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr11_+_34643600 0.122 ENST00000530286.1
ENST00000533754.1
EHF

ets homologous factor

chr6_+_97372645 0.120 ENST00000536676.1
ENST00000544166.1
KLHL32

kelch-like family member 32

chr2_-_239149300 0.119 ENST00000436051.1
HES6
hes family bHLH transcription factor 6
chr16_-_4987065 0.118 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chr18_-_74728998 0.118 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP










myelin basic protein










chr2_+_210444298 0.116 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr2_+_27719697 0.115 ENST00000264717.2
ENST00000424318.2
GCKR

glucokinase (hexokinase 4) regulator

chr1_-_32801825 0.114 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chrX_+_37545012 0.112 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr10_+_60759378 0.112 ENST00000432535.1
LINC00844
long intergenic non-protein coding RNA 844
chr5_-_146833222 0.112 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr6_-_46889694 0.111 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116


G protein-coupled receptor 116


chr1_+_164529004 0.110 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1



pre-B-cell leukemia homeobox 1



chr4_-_138453559 0.110 ENST00000511115.1
PCDH18
protocadherin 18
chr2_+_177015950 0.108 ENST00000306324.3
HOXD4
homeobox D4
chr7_-_22233442 0.108 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr11_+_5711010 0.108 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr6_+_30848771 0.107 ENST00000503180.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr22_-_38480100 0.106 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr17_+_72428266 0.106 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr22_+_25595817 0.106 ENST00000215855.2
ENST00000404334.1
CRYBB3

crystallin, beta B3

chr4_-_52883786 0.105 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr4_-_138453606 0.105 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr7_-_103629963 0.105 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr13_+_98795664 0.104 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_152178320 0.103 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr3_+_44626446 0.102 ENST00000441021.1
ENST00000322734.2
ZNF660

zinc finger protein 660

chr4_-_10459009 0.102 ENST00000507515.1
ZNF518B
zinc finger protein 518B
chr3_-_171489085 0.102 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chrX_+_9880412 0.101 ENST00000418909.2
SHROOM2
shroom family member 2
chrX_-_72434628 0.100 ENST00000536638.1
ENST00000373517.3
NAP1L2

nucleosome assembly protein 1-like 2

chr20_-_19738569 0.099 ENST00000598007.1
AL121761.2
Uncharacterized protein
chr9_+_116638630 0.099 ENST00000452710.1
ENST00000374124.4
ZNF618

zinc finger protein 618

chr7_-_121944491 0.099 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr15_+_92937144 0.098 ENST00000539113.1
ENST00000555434.1
ST8SIA2

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

chr17_+_9066252 0.097 ENST00000436734.1
NTN1
netrin 1
chr7_+_139528952 0.097 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1



thromboxane A synthase 1 (platelet)



chr8_-_70745575 0.097 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr7_+_94537542 0.096 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr2_+_210443993 0.096 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr20_+_19738300 0.096 ENST00000432334.1
RP1-122P22.2
RP1-122P22.2
chr4_-_10458982 0.094 ENST00000326756.3
ZNF518B
zinc finger protein 518B
chr4_+_69917078 0.094 ENST00000502942.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr7_+_114055052 0.094 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr11_+_34645791 0.094 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
EHF


ets homologous factor


chr3_-_120400960 0.093 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr19_-_22379753 0.093 ENST00000397121.2
ZNF676
zinc finger protein 676
chr8_+_77316233 0.093 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
RP11-706J10.3
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr3_-_167813132 0.093 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr6_+_97372596 0.092 ENST00000369261.4
KLHL32
kelch-like family member 32
chr6_+_97372734 0.092 ENST00000539200.1
KLHL32
kelch-like family member 32
chr1_-_234667504 0.091 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1

RP5-855F14.1

chrX_+_103028638 0.091 ENST00000434483.1
PLP1
proteolipid protein 1
chr10_+_11207088 0.090 ENST00000608830.1
CELF2
CUGBP, Elav-like family member 2
chr1_+_164528866 0.090 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chrX_+_103029314 0.090 ENST00000429977.1
PLP1
proteolipid protein 1
chr5_-_157079372 0.089 ENST00000311371.5
SOX30
SRY (sex determining region Y)-box 30
chr19_-_19739321 0.088 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr7_+_30960915 0.088 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1


aquaporin 1 (Colton blood group)


chr5_-_1112141 0.088 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr5_+_76012009 0.088 ENST00000505600.1
F2R
coagulation factor II (thrombin) receptor
chr16_-_28550348 0.088 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr17_-_39681578 0.087 ENST00000593096.1
KRT19
keratin 19
chr2_+_65215604 0.086 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr15_-_81202118 0.086 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr10_-_61122220 0.086 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C






family with sequence similarity 13, member C






chr3_-_139258521 0.086 ENST00000483943.2
ENST00000232219.2
ENST00000492918.1
RBP1


retinol binding protein 1, cellular


chr14_-_25519095 0.086 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6



syntaxin binding protein 6 (amisyn)



chr19_-_35323762 0.085 ENST00000590963.1
CTC-523E23.4
CTC-523E23.4
chr19_-_56904799 0.085 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
ZNF582



zinc finger protein 582



chr2_-_25451065 0.085 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr16_-_29275800 0.085 ENST00000567984.1
RP11-426C22.6
RP11-426C22.6
chr1_-_177133818 0.083 ENST00000424564.2
ENST00000361833.2
ASTN1

astrotactin 1

chr5_+_36606700 0.082 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_-_65106110 0.082 ENST00000562882.1
ENST00000567934.1
CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

chr19_-_51891209 0.082 ENST00000221973.3
ENST00000596399.1
LIM2

lens intrinsic membrane protein 2, 19kDa

chr6_+_31865552 0.081 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr20_-_62493217 0.081 ENST00000601296.1
C20ORF135
C20ORF135
chr7_+_73245193 0.080 ENST00000340958.2
CLDN4
claudin 4
chr7_-_105926058 0.079 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr6_-_137366096 0.078 ENST00000316649.5
ENST00000367746.3
IL20RA

interleukin 20 receptor, alpha

chr10_-_105845536 0.077 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr20_-_1165117 0.077 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr3_+_134514093 0.077 ENST00000398015.3
EPHB1
EPH receptor B1
chr6_-_46048116 0.077 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr19_-_57967854 0.077 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr14_+_105941118 0.077 ENST00000550577.1
ENST00000538259.2
CRIP2

cysteine-rich protein 2

chr11_+_196738 0.077 ENST00000325113.4
ENST00000342593.5
ODF3

outer dense fiber of sperm tails 3

chr6_-_133055896 0.076 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3





vanin 3





chr3_+_132757215 0.075 ENST00000321871.6
ENST00000393130.3
ENST00000514894.1
ENST00000512662.1
TMEM108



transmembrane protein 108



chr6_-_75912508 0.075 ENST00000416123.2
COL12A1
collagen, type XII, alpha 1
chr14_+_74815116 0.074 ENST00000256362.4
VRTN
vertebrae development associated
chr14_-_73493825 0.074 ENST00000318876.5
ENST00000556143.1
ZFYVE1

zinc finger, FYVE domain containing 1

chr5_+_36606992 0.074 ENST00000505202.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_9880590 0.074 ENST00000452575.1
SHROOM2
shroom family member 2
chr12_-_2966193 0.073 ENST00000382678.3
AC005841.1
Uncharacterized protein ENSP00000372125
chr10_+_11206925 0.073 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr7_+_29234101 0.072 ENST00000435288.2
CHN2
chimerin 2
chr5_-_150284351 0.072 ENST00000427179.1
ZNF300
zinc finger protein 300
chr7_+_106505696 0.072 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr9_-_73483926 0.072 ENST00000396283.1
ENST00000361823.5
TRPM3

transient receptor potential cation channel, subfamily M, member 3

chr3_+_183353356 0.071 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr2_+_33172221 0.071 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr3_+_181429704 0.071 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr6_-_30654977 0.071 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr7_-_127672146 0.071 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr19_+_58095501 0.071 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1





zinc finger protein interacting with K protein 1





chr12_-_62653903 0.070 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr17_-_39123144 0.070 ENST00000355612.2
KRT39
keratin 39
chr9_-_130616915 0.070 ENST00000344849.3
ENG
endoglin
chrX_+_100333709 0.069 ENST00000372930.4
TMEM35
transmembrane protein 35
chr6_-_28304152 0.069 ENST00000435857.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr5_-_67730240 0.069 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr7_+_29234028 0.069 ENST00000222792.6
CHN2
chimerin 2
chr2_-_160568529 0.068 ENST00000418770.1
AC009961.3
AC009961.3
chr12_+_94071341 0.068 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr10_+_11047259 0.068 ENST00000379261.4
ENST00000416382.2
CELF2

CUGBP, Elav-like family member 2

chr19_-_5340730 0.067 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr2_+_17721937 0.067 ENST00000451533.1
VSNL1
visinin-like 1
chr2_-_165697717 0.067 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr2_-_99485825 0.067 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr3_+_127348005 0.067 ENST00000342480.6
PODXL2
podocalyxin-like 2
chrX_+_69642881 0.066 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr6_-_116447283 0.066 ENST00000452729.1
ENST00000243222.4
COL10A1

collagen, type X, alpha 1

chr12_-_57634475 0.066 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr2_-_100721801 0.066 ENST00000424600.1
ENST00000441400.1
AFF3

AF4/FMR2 family, member 3

chr9_+_116638562 0.066 ENST00000374126.5
ENST00000288466.7
ZNF618

zinc finger protein 618

chr5_-_115910091 0.066 ENST00000257414.8
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr16_-_31085033 0.065 ENST00000414399.1
ZNF668
zinc finger protein 668
chr3_+_151986709 0.065 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1



muscleblind-like splicing regulator 1



chr18_+_3450161 0.065 ENST00000551402.1
ENST00000577543.1
TGIF1

TGFB-induced factor homeobox 1

chr9_+_103235365 0.065 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_169075554 0.065 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_57276661 0.064 ENST00000598320.1
AC068620.1
Uncharacterized protein
chr12_-_18243119 0.064 ENST00000538724.1
ENST00000229002.2
RERGL

RERG/RAS-like

chr2_-_109605663 0.064 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr7_+_94537247 0.064 ENST00000422324.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr15_-_54267147 0.063 ENST00000558866.1
ENST00000558920.1
RP11-643A5.2

RP11-643A5.2

chr8_-_33424636 0.063 ENST00000256257.1
RNF122
ring finger protein 122
chr14_-_73493784 0.063 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr6_-_30815936 0.063 ENST00000442852.1
XXbac-BPG27H4.8
XXbac-BPG27H4.8
chr5_-_115872124 0.063 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_-_31902614 0.063 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr4_-_184243561 0.063 ENST00000514470.1
ENST00000541814.1
CLDN24

claudin 24

chrX_-_51812268 0.061 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B





melanoma antigen family D, 4B





chr17_+_36584662 0.061 ENST00000431231.2
ENST00000437668.3
ARHGAP23

Rho GTPase activating protein 23

chr2_-_170219037 0.061 ENST00000443831.1
LRP2
low density lipoprotein receptor-related protein 2
chr11_+_114168085 0.060 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr3_+_69985792 0.060 ENST00000531774.1
MITF
microphthalmia-associated transcription factor

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.0 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0048675 axon extension(GO:0048675)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.0 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.0 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0035377 transepithelial water transport(GO:0035377)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.0 GO:0048369 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370)
0.0 0.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.0 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.0 0.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.0 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.0 GO:0098942 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.0 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:1990357 terminal web(GO:1990357)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.0 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway