Motif ID: SOX10_SOX15

Z-value: 0.413

Transcription factors associated with SOX10_SOX15:

Gene SymbolEntrez IDGene Name
SOX10 ENSG00000100146.12 SOX10
SOX15 ENSG00000129194.3 SOX15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX15hg19_v2_chr17_-_7493390_7493488-0.637.0e-02Click!
SOX10hg19_v2_chr22_-_38380543_383805690.206.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of SOX10_SOX15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_138287168 0.842 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr1_-_200992827 0.565 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr5_-_54281491 0.538 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr6_-_127840048 0.509 ENST00000467753.1
SOGA3
SOGA family member 3
chr3_+_111260980 0.495 ENST00000438817.2
CD96
CD96 molecule
chr6_-_127840336 0.388 ENST00000525778.1
SOGA3
SOGA family member 3
chr6_-_127840021 0.296 ENST00000465909.2
SOGA3
SOGA family member 3
chrX_-_142722897 0.273 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr4_-_186877502 0.268 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr3_+_111260856 0.259 ENST00000352690.4
CD96
CD96 molecule
chr3_+_111260954 0.259 ENST00000283285.5
CD96
CD96 molecule
chr12_+_54378923 0.258 ENST00000303460.4
HOXC10
homeobox C10
chr6_-_134861089 0.244 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr6_+_114178512 0.240 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chrX_-_32173579 0.228 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chr6_+_43968306 0.224 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr6_-_127840453 0.223 ENST00000556132.1
SOGA3
SOGA family member 3
chr6_-_139613269 0.216 ENST00000358430.3
TXLNB
taxilin beta
chr4_-_176733377 0.205 ENST00000505375.1
GPM6A
glycoprotein M6A
chr18_+_6729725 0.205 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chr11_-_6677018 0.201 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr7_+_106505696 0.200 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr12_+_54378849 0.199 ENST00000515593.1
HOXC10
homeobox C10
chr4_-_186732048 0.190 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr18_+_6729698 0.189 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr4_-_186877481 0.187 ENST00000444781.1
ENST00000432655.1
SORBS2

sorbin and SH3 domain containing 2

chr15_+_63335899 0.187 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr8_-_124553437 0.175 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr12_-_95611149 0.174 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6


FYVE, RhoGEF and PH domain containing 6


chr10_-_99030395 0.169 ENST00000355366.5
ENST00000371027.1
ARHGAP19

Rho GTPase activating protein 19

chr17_-_56406117 0.166 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr12_+_8849773 0.164 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr7_-_32111009 0.159 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C


phosphodiesterase 1C, calmodulin-dependent 70kDa


chr3_-_4927447 0.156 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr3_-_46904946 0.150 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr6_+_72596604 0.146 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr22_+_37959647 0.144 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr3_-_48470838 0.143 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr10_-_61900762 0.143 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_67442409 0.140 ENST00000414404.1
ENST00000433133.1
AC078941.1

AC078941.1

chr13_-_41593425 0.139 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_-_46623441 0.138 ENST00000330070.4
HOXB2
homeobox B2
chr13_-_110959478 0.138 ENST00000543140.1
ENST00000375820.4
COL4A1

collagen, type IV, alpha 1

chr15_+_57210961 0.137 ENST00000557843.1
TCF12
transcription factor 12
chr1_+_203096831 0.137 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr11_-_5364809 0.133 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr3_-_46904918 0.133 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr11_+_7273181 0.130 ENST00000318881.6
SYT9
synaptotagmin IX
chr20_-_52645231 0.128 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr4_-_109090106 0.126 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr4_-_186578674 0.125 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr3_-_157221128 0.122 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr2_-_72374948 0.122 ENST00000546307.1
ENST00000474509.1
CYP26B1

cytochrome P450, family 26, subfamily B, polypeptide 1

chr13_+_30002846 0.122 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr1_+_240255166 0.120 ENST00000319653.9
FMN2
formin 2
chr2_-_37501692 0.119 ENST00000443977.1
PRKD3
protein kinase D3
chr12_-_31477072 0.118 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chrX_+_70503433 0.117 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO



non-POU domain containing, octamer-binding



chr3_+_189349162 0.114 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63





chr12_-_71003568 0.109 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB




protein tyrosine phosphatase, receptor type, B




chr21_-_16437126 0.108 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr2_-_72375167 0.108 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr21_-_16437255 0.108 ENST00000400199.1
ENST00000400202.1
NRIP1

nuclear receptor interacting protein 1

chr22_-_39052300 0.107 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr4_-_109089573 0.107 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr20_+_6748311 0.104 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr4_-_186732241 0.097 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr3_-_151102529 0.096 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr20_-_23066953 0.095 ENST00000246006.4
CD93
CD93 molecule
chr13_-_33780133 0.094 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr13_+_30002741 0.094 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr11_+_61595572 0.093 ENST00000517312.1
FADS2
fatty acid desaturase 2
chr18_-_22932080 0.092 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521


zinc finger protein 521


chr17_-_42906965 0.092 ENST00000586267.1
GJC1
gap junction protein, gamma 1, 45kDa
chr2_+_69240302 0.092 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr7_+_23146271 0.091 ENST00000545771.1
KLHL7
kelch-like family member 7
chr7_+_134551583 0.091 ENST00000435928.1
CALD1
caldesmon 1
chr2_-_171571077 0.088 ENST00000409786.1
AC007405.2
long intergenic non-protein coding RNA 1124
chr22_+_19710468 0.088 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr13_+_111767650 0.088 ENST00000449979.1
ENST00000370623.3
ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

chr17_-_7297833 0.086 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr18_-_74207146 0.086 ENST00000443185.2
ZNF516
zinc finger protein 516
chr14_-_80678512 0.085 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr20_-_45985172 0.084 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr7_-_111846435 0.084 ENST00000437633.1
ENST00000428084.1
DOCK4

dedicator of cytokinesis 4

chr12_-_105478339 0.084 ENST00000424857.2
ENST00000258494.9
ALDH1L2

aldehyde dehydrogenase 1 family, member L2

chr2_-_70475730 0.083 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1


TIA1 cytotoxic granule-associated RNA binding protein


chr12_-_42631529 0.083 ENST00000548917.1
YAF2
YY1 associated factor 2
chr3_-_71353892 0.081 ENST00000484350.1
FOXP1
forkhead box P1
chr2_-_70475701 0.081 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr10_+_114710211 0.080 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr2_+_70056762 0.078 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr6_+_87865262 0.078 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chrX_-_21776281 0.078 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr9_-_127358087 0.078 ENST00000475178.1
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr3_-_192635943 0.078 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr19_+_13906250 0.078 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chrX_+_70503037 0.077 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr2_-_70475586 0.077 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr14_+_100070869 0.077 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr12_+_9066472 0.077 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr6_+_83777374 0.076 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1


dopey family member 1


chr15_+_85144217 0.074 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2









zinc finger and SCAN domain containing 2









chr21_+_30672433 0.074 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_-_45984401 0.073 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr17_-_7297519 0.073 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chr18_-_53019208 0.072 ENST00000562607.1
TCF4
transcription factor 4
chr4_+_146403912 0.072 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1


SMAD family member 1


chr13_+_98795434 0.072 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr13_+_98795505 0.072 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_-_65398647 0.072 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr6_-_130536774 0.071 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr11_-_8892464 0.071 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5




suppression of tumorigenicity 5




chr3_+_189507523 0.070 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr10_-_75351088 0.070 ENST00000451492.1
ENST00000413442.1
USP54

ubiquitin specific peptidase 54

chr5_-_157002775 0.069 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr15_+_81293254 0.069 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chrX_+_80457442 0.069 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr3_+_113616317 0.068 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr15_+_57210818 0.068 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12




transcription factor 12




chr1_+_2066252 0.067 ENST00000466352.1
PRKCZ
protein kinase C, zeta
chrX_-_45629661 0.067 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2

RP6-99M1.2

chr3_-_123123407 0.066 ENST00000466617.1
ADCY5
adenylate cyclase 5
chr10_+_99079008 0.066 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr18_+_72201664 0.065 ENST00000358821.3
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr2_+_66662690 0.065 ENST00000488550.1
MEIS1
Meis homeobox 1
chrX_-_50557302 0.065 ENST00000289292.7
SHROOM4
shroom family member 4
chr5_-_176037105 0.065 ENST00000303991.4
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr2_+_74685527 0.064 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WBP1


WW domain binding protein 1


chr15_-_82338460 0.064 ENST00000558133.1
ENST00000329713.4
MEX3B

mex-3 RNA binding family member B

chr14_+_77228532 0.063 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr1_-_226926864 0.062 ENST00000429204.1
ENST00000366784.1
ITPKB

inositol-trisphosphate 3-kinase B

chr3_+_189507432 0.061 ENST00000354600.5
TP63
tumor protein p63
chr1_-_95391315 0.061 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr17_-_18950310 0.060 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chrX_+_70503526 0.060 ENST00000413858.1
ENST00000450092.1
NONO

non-POU domain containing, octamer-binding

chr3_+_52719936 0.060 ENST00000418458.1
ENST00000394799.2
GNL3

guanine nucleotide binding protein-like 3 (nucleolar)

chr16_-_30798492 0.060 ENST00000262525.4
ZNF629
zinc finger protein 629
chr2_+_66662510 0.059 ENST00000272369.9
ENST00000407092.2
MEIS1

Meis homeobox 1

chr12_-_49504449 0.059 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr7_-_15601595 0.059 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr6_-_119031228 0.059 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L


centrosomal protein 85kDa-like


chr5_-_39424961 0.058 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr11_+_111808119 0.058 ENST00000531396.1
DIXDC1
DIX domain containing 1
chr1_-_234614849 0.058 ENST00000040877.1
TARBP1
TAR (HIV-1) RNA binding protein 1
chr6_+_90192974 0.057 ENST00000520458.1
ANKRD6
ankyrin repeat domain 6
chr1_+_47799542 0.057 ENST00000471289.2
ENST00000450808.2
CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

chr14_+_97263641 0.057 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr2_+_66662249 0.057 ENST00000560281.2
MEIS1
Meis homeobox 1
chr3_-_157221380 0.057 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr4_+_154387480 0.056 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922


KIAA0922


chr20_-_62284766 0.056 ENST00000370053.1
STMN3
stathmin-like 3
chr3_-_157221357 0.056 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr5_-_157002749 0.055 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19


ADAM metallopeptidase domain 19


chr16_+_84801852 0.055 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr7_-_137039191 0.055 ENST00000438969.2
AC078842.3
AC078842.3
chr6_+_108881012 0.055 ENST00000343882.6
FOXO3
forkhead box O3
chr22_+_39052632 0.054 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr17_-_7590745 0.054 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr12_+_79371565 0.053 ENST00000551304.1
SYT1
synaptotagmin I
chr15_+_57211318 0.053 ENST00000557947.1
TCF12
transcription factor 12
chr13_+_98795664 0.053 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr20_-_56284816 0.052 ENST00000395819.3
ENST00000341744.3
PMEPA1

prostate transmembrane protein, androgen induced 1

chr6_+_122720681 0.052 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr4_-_140477928 0.051 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_-_128415844 0.051 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr2_+_74685413 0.051 ENST00000233615.2
WBP1
WW domain binding protein 1
chr6_-_165989936 0.051 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr19_+_1452188 0.051 ENST00000587149.1
APC2
adenomatosis polyposis coli 2
chr6_-_128222103 0.050 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS


thymocyte selection associated


chr14_+_96343100 0.050 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr12_-_96793142 0.050 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17


cyclin-dependent kinase 17


chr17_+_75447326 0.050 ENST00000591088.1
SEPT9
septin 9
chr17_-_77924627 0.050 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chr1_+_68150744 0.049 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr15_-_56035177 0.049 ENST00000389286.4
ENST00000561292.1
PRTG

protogenin

chr11_+_111807863 0.049 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr8_-_116681686 0.048 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr14_+_20923350 0.048 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1











APEX nuclease (multifunctional DNA repair enzyme) 1











chr3_+_10857885 0.048 ENST00000254488.2
ENST00000454147.1
SLC6A11

solute carrier family 6 (neurotransmitter transporter), member 11

chr8_+_77316233 0.048 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
RP11-706J10.3
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr3_-_129513259 0.047 ENST00000329333.5
TMCC1
transmembrane and coiled-coil domain family 1
chrX_+_69674943 0.047 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr13_+_49684445 0.047 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr13_-_24007815 0.047 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr15_-_70388943 0.047 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3






transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)






chrX_-_11284095 0.047 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr3_+_141105235 0.046 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_122018346 0.046 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr3_-_123339343 0.046 ENST00000578202.1
MYLK
myosin light chain kinase
chr12_+_95611536 0.046 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_154155675 0.046 ENST00000330188.9
ENST00000341485.5
TPM3

tropomyosin 3

chr6_-_161695074 0.046 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4


1-acylglycerol-3-phosphate O-acyltransferase 4


chr12_-_11339543 0.045 ENST00000334266.1
TAS2R42
taste receptor, type 2, member 42
chr17_-_46690839 0.045 ENST00000498634.2
HOXB8
homeobox B8
chr22_-_38480100 0.045 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr17_+_15603447 0.045 ENST00000395893.2
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr1_+_33722080 0.044 ENST00000483388.1
ENST00000539719.1
ZNF362

zinc finger protein 362

chr15_+_52043813 0.043 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr15_+_93426514 0.043 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.2 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.0 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042585 female germ cell nucleus(GO:0001674) germinal vesicle(GO:0042585)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.0 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction