Motif ID: SMAD4

Z-value: 0.976


Transcription factors associated with SMAD4:

Gene SymbolEntrez IDGene Name
SMAD4 ENSG00000141646.9 SMAD4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48494361_484944260.333.9e-01Click!


Activity profile for motif SMAD4.

activity profile for motif SMAD4


Sorted Z-values histogram for motif SMAD4

Sorted Z-values for motif SMAD4



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_31360887 0.809 ENST00000420311.2
ENST00000356174.3
ENST00000324589.5
GALNT14


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)


chr22_+_31518938 0.597 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr2_-_71062938 0.506 ENST00000410009.3
CD207
CD207 molecule, langerin
chr19_+_48898132 0.488 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr19_-_51220176 0.454 ENST00000359082.3
ENST00000293441.1
SHANK1

SH3 and multiple ankyrin repeat domains 1

chr8_+_104384616 0.451 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr16_+_2880296 0.449 ENST00000571723.1
ZG16B
zymogen granule protein 16B
chr14_+_69726656 0.430 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chrX_+_16141667 0.426 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr11_+_1430629 0.425 ENST00000528596.1
BRSK2
BR serine/threonine kinase 2
chr19_-_51017127 0.405 ENST00000389208.4
ASPDH
aspartate dehydrogenase domain containing
chr3_-_55515400 0.387 ENST00000497027.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr16_+_29150963 0.375 ENST00000563477.1
RP11-426C22.5
RP11-426C22.5
chr17_+_74536115 0.370 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr8_+_104383728 0.368 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr19_+_11649532 0.365 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1


calponin 1, basic, smooth muscle


chr8_+_104383759 0.363 ENST00000415886.2
CTHRC1
collagen triple helix repeat containing 1
chr22_-_37880543 0.356 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_+_100743031 0.352 ENST00000423738.3
ARMCX4
armadillo repeat containing, X-linked 4
chr17_+_61562201 0.333 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
ACE


angiotensin I converting enzyme


chr3_-_55515202 0.331 ENST00000482079.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr2_+_181988620 0.329 ENST00000428474.1
ENST00000424655.1
AC104820.2

AC104820.2

chr19_+_41281060 0.325 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr1_+_209859510 0.324 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr1_-_159832438 0.291 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr22_+_38382163 0.290 ENST00000333418.4
ENST00000427034.1
POLR2F

polymerase (RNA) II (DNA directed) polypeptide F

chr13_-_36429763 0.288 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr10_-_46313036 0.275 ENST00000411791.3
FAM25E
family with sequence similarity 25, member E
chr6_-_113953705 0.275 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr1_+_27668505 0.274 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr12_+_116985896 0.271 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chr16_+_2880369 0.271 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr19_+_41281282 0.266 ENST00000263369.3
MIA
melanoma inhibitory activity
chrX_-_48328631 0.259 ENST00000429543.1
ENST00000317669.5
SLC38A5

solute carrier family 38, member 5

chr19_+_4229495 0.257 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr2_-_70944855 0.255 ENST00000415348.1
ADD2
adducin 2 (beta)
chr14_+_69726968 0.254 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr19_-_55672037 0.251 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr4_+_71384300 0.250 ENST00000504451.1
AMTN
amelotin
chr11_+_45943169 0.249 ENST00000529052.1
ENST00000531526.1
GYLTL1B

glycosyltransferase-like 1B

chr19_+_41281416 0.243 ENST00000597140.1
MIA
melanoma inhibitory activity
chr16_+_2880157 0.243 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr15_-_45694380 0.242 ENST00000561148.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr19_+_11650709 0.238 ENST00000586059.1
CNN1
calponin 1, basic, smooth muscle
chr4_+_71384257 0.237 ENST00000339336.4
AMTN
amelotin
chr16_-_67260901 0.236 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29


AC040160.1
leucine rich repeat containing 29


Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chrX_-_50557014 0.232 ENST00000376020.2
SHROOM4
shroom family member 4
chr12_-_6740802 0.229 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr22_-_33968239 0.227 ENST00000452586.2
ENST00000421768.1
LARGE

like-glycosyltransferase

chr5_+_176784837 0.227 ENST00000408923.3
RGS14
regulator of G-protein signaling 14
chr3_+_122296443 0.224 ENST00000464300.2
PARP15
poly (ADP-ribose) polymerase family, member 15
chr20_-_23967432 0.223 ENST00000286890.4
ENST00000278765.4
GGTLC1

gamma-glutamyltransferase light chain 1

chr6_-_4347271 0.217 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr9_+_35673853 0.217 ENST00000378357.4
CA9
carbonic anhydrase IX
chr19_+_35773242 0.215 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chrX_-_74145273 0.215 ENST00000055682.6
KIAA2022
KIAA2022
chr12_-_2027639 0.215 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4


calcium channel, voltage-dependent, alpha 2/delta subunit 4


chr14_+_69726864 0.214 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr20_-_30433396 0.212 ENST00000375978.3
FOXS1
forkhead box S1
chr20_+_1875378 0.211 ENST00000356025.3
SIRPA
signal-regulatory protein alpha
chr11_+_1411129 0.211 ENST00000308219.9
ENST00000528841.1
ENST00000531197.1
ENST00000308230.5
BRSK2



BR serine/threonine kinase 2



chr3_-_48632593 0.210 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr20_+_55108302 0.210 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr16_+_25228242 0.209 ENST00000219660.5
AQP8
aquaporin 8
chr17_-_1549011 0.207 ENST00000571272.1
ENST00000263071.4
ENST00000348987.3
SCARF1


scavenger receptor class F, member 1


chr20_+_24449821 0.207 ENST00000376862.3
SYNDIG1
synapse differentiation inducing 1
chr20_+_30598231 0.206 ENST00000300415.8
ENST00000262659.8
CCM2L

cerebral cavernous malformation 2-like

chr4_+_48485341 0.205 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr19_-_10628098 0.205 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr11_-_26593779 0.200 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr10_-_22498950 0.200 ENST00000422359.2
EBLN1
endogenous Bornavirus-like nucleoprotein 1
chr17_-_70053866 0.199 ENST00000540802.1
RP11-84E24.2
RP11-84E24.2
chr20_+_1875110 0.198 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr6_-_127780510 0.198 ENST00000487331.2
ENST00000483725.3
KIAA0408

KIAA0408

chr3_+_111718036 0.197 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_46919235 0.193 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr3_+_111718173 0.190 ENST00000494932.1
TAGLN3
transgelin 3
chr15_+_49715449 0.187 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr6_-_93433538 0.184 ENST00000404689.2
RP11-127B16.1
RP11-127B16.1
chrX_-_48328551 0.183 ENST00000376876.3
SLC38A5
solute carrier family 38, member 5
chr1_-_100643765 0.183 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39


leucine rich repeat containing 39


chr22_-_21579843 0.183 ENST00000405188.4
GGT2
gamma-glutamyltransferase 2
chr19_-_47975143 0.181 ENST00000597014.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr11_+_1411503 0.179 ENST00000526678.1
BRSK2
BR serine/threonine kinase 2
chrX_-_138304939 0.178 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr15_+_89584447 0.177 ENST00000565938.1
RP11-326A19.4
RP11-326A19.4
chr12_-_42631529 0.176 ENST00000548917.1
YAF2
YY1 associated factor 2
chr18_+_11857439 0.175 ENST00000602628.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr10_-_73848764 0.170 ENST00000317376.4
ENST00000412663.1
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr2_+_71127699 0.168 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr16_-_77468945 0.167 ENST00000282849.5
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr22_+_27043175 0.166 ENST00000440347.1
ENST00000450203.1
ENST00000430483.1
MIAT


myocardial infarction associated transcript (non-protein coding)


chr19_+_51628165 0.163 ENST00000250360.3
ENST00000440804.3
SIGLEC9

sialic acid binding Ig-like lectin 9

chr10_+_88414338 0.162 ENST00000241891.5
ENST00000443292.1
OPN4

opsin 4

chr22_+_25003606 0.160 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr18_+_44526786 0.159 ENST00000245121.5
ENST00000356157.7
KATNAL2

katanin p60 subunit A-like 2

chr9_+_72658490 0.159 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr4_-_186696636 0.158 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_242801031 0.157 ENST00000334409.5
PDCD1
programmed cell death 1
chr15_-_102285007 0.157 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr1_+_203096831 0.156 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr11_-_118135160 0.155 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr19_+_41949054 0.154 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chr1_-_112106578 0.153 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr22_+_22676808 0.151 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr11_+_1430983 0.149 ENST00000524702.1
BRSK2
BR serine/threonine kinase 2
chr6_-_39399087 0.149 ENST00000229913.5
ENST00000541946.1
ENST00000394362.1
KIF6


kinesin family member 6


chr5_+_82767583 0.149 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr11_-_65150103 0.148 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45




solute carrier family 25, member 45




chr16_+_66638616 0.147 ENST00000564060.1
ENST00000565922.1
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr5_-_169626104 0.147 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1

CTB-27N1.1

chr17_-_18585131 0.147 ENST00000443457.1
ENST00000583002.1
ZNF286B

zinc finger protein 286B

chr10_-_73848531 0.145 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_+_7580944 0.145 ENST00000597229.1
ZNF358
zinc finger protein 358
chr9_-_140142181 0.145 ENST00000484720.1
FAM166A
family with sequence similarity 166, member A
chr11_-_74204692 0.145 ENST00000528085.1
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr9_-_37034028 0.143 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr14_+_97925151 0.143 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1


CTD-2506J14.1


chr11_-_72385437 0.143 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A


phosphodiesterase 2A, cGMP-stimulated


chr1_+_26348259 0.143 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chrX_-_102757802 0.141 ENST00000372633.1
RAB40A
RAB40A, member RAS oncogene family
chr22_+_22988816 0.141 ENST00000480559.1
ENST00000448514.1
GGTLC2

gamma-glutamyltransferase light chain 2

chr6_+_168434678 0.141 ENST00000496008.1
KIF25
kinesin family member 25
chr22_+_25003568 0.141 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr22_+_23063100 0.139 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr19_+_39759154 0.139 ENST00000331982.5
IFNL2
interferon, lambda 2
chr17_-_7080801 0.138 ENST00000572879.1
ASGR1
asialoglycoprotein receptor 1
chr11_+_115498761 0.137 ENST00000424313.2
AP000997.1
AP000997.1
chrX_-_110513703 0.137 ENST00000324068.1
CAPN6
calpain 6
chr20_-_56265680 0.137 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr12_-_53594227 0.136 ENST00000550743.2
ITGB7
integrin, beta 7
chr11_+_60739115 0.135 ENST00000344028.5
ENST00000346437.4
CD6

CD6 molecule

chr22_-_29711645 0.135 ENST00000401450.3
RASL10A
RAS-like, family 10, member A
chr2_+_232575168 0.135 ENST00000440384.1
PTMA
prothymosin, alpha
chr10_+_88414298 0.134 ENST00000372071.2
OPN4
opsin 4
chr10_+_94451574 0.133 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr17_-_8027402 0.133 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7


hes family bHLH transcription factor 7


chr19_-_11688447 0.132 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr17_-_42019836 0.131 ENST00000225992.3
PPY
pancreatic polypeptide
chr19_-_54984354 0.130 ENST00000301200.2
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr15_-_42186248 0.128 ENST00000320955.6
SPTBN5
spectrin, beta, non-erythrocytic 5
chr10_-_81708854 0.128 ENST00000372292.3
SFTPD
surfactant protein D
chrX_+_100663243 0.128 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr11_-_60623437 0.128 ENST00000332539.4
PTGDR2
prostaglandin D2 receptor 2
chr1_+_207038699 0.128 ENST00000367098.1
IL20
interleukin 20
chr16_+_2880254 0.128 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr2_+_181988560 0.128 ENST00000424170.1
ENST00000435411.1
AC104820.2

AC104820.2

chr11_+_1463728 0.128 ENST00000544817.1
BRSK2
BR serine/threonine kinase 2
chr15_+_75182346 0.127 ENST00000569931.1
ENST00000352410.4
ENST00000566377.1
ENST00000569233.1
ENST00000567132.1
ENST00000564633.1
ENST00000568907.1
ENST00000563422.1
ENST00000564003.1
ENST00000562800.1
ENST00000563786.1
ENST00000535694.1
ENST00000323744.6
ENST00000568828.1
ENST00000562606.1
ENST00000565576.1
ENST00000567570.1
MPI
















mannose phosphate isomerase
















chr9_-_100707116 0.127 ENST00000259456.3
HEMGN
hemogen
chr12_+_52203789 0.127 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr2_-_208030295 0.127 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr22_+_25003626 0.127 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1


gamma-glutamyltransferase 1


chr2_-_74667612 0.126 ENST00000305557.5
ENST00000233330.6
RTKN

rhotekin

chr3_-_8686479 0.126 ENST00000544814.1
ENST00000427408.1
SSUH2

ssu-2 homolog (C. elegans)

chr17_+_7344057 0.125 ENST00000575398.1
ENST00000575082.1
FGF11

fibroblast growth factor 11

chr4_+_55524085 0.123 ENST00000412167.2
ENST00000288135.5
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr12_+_121088291 0.123 ENST00000351200.2
CABP1
calcium binding protein 1
chr2_-_73520667 0.122 ENST00000545030.1
ENST00000436467.2
EGR4

early growth response 4

chr19_-_3801789 0.122 ENST00000590849.1
ENST00000395045.2
MATK

megakaryocyte-associated tyrosine kinase

chr17_-_56406117 0.121 ENST00000268893.6
ENST00000355701.3
BZRAP1

benzodiazepine receptor (peripheral) associated protein 1

chr12_-_12491608 0.121 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr6_+_39760129 0.120 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chrX_-_48326683 0.120 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chr7_+_149416439 0.120 ENST00000497895.1
KRBA1
KRAB-A domain containing 1
chr5_-_36301984 0.119 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr20_+_42984330 0.119 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr22_-_21581926 0.119 ENST00000401924.1
GGT2
gamma-glutamyltransferase 2
chr17_-_56405407 0.117 ENST00000343736.4
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chr19_-_55881741 0.116 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11


interleukin 11


chr10_+_88718397 0.116 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chrX_+_102631248 0.116 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr1_-_156647189 0.116 ENST00000368223.3
NES
nestin
chr11_-_3186494 0.116 ENST00000389989.3
ENST00000542243.1
OSBPL5

oxysterol binding protein-like 5

chr11_-_58190786 0.115 ENST00000302581.2
OR5B2
olfactory receptor, family 5, subfamily B, member 2
chr12_+_121078355 0.114 ENST00000316803.3
CABP1
calcium binding protein 1
chr22_-_20368028 0.114 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr1_-_113257905 0.113 ENST00000464951.1
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr3_-_12200851 0.113 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr12_-_11422739 0.113 ENST00000279573.7
PRB3
proline-rich protein BstNI subfamily 3
chr1_+_156830678 0.113 ENST00000524377.1
ENST00000358660.3
NTRK1

neurotrophic tyrosine kinase, receptor, type 1

chr11_-_61596753 0.112 ENST00000448607.1
ENST00000421879.1
FADS1

fatty acid desaturase 1

chr1_+_110036674 0.112 ENST00000393709.3
CYB561D1
cytochrome b561 family, member D1
chrX_+_102841064 0.112 ENST00000469586.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr10_+_106937525 0.111 ENST00000369699.4
SORCS3
sortilin-related VPS10 domain containing receptor 3
chrX_+_102631844 0.111 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chrX_-_33146477 0.110 ENST00000378677.2
DMD
dystrophin
chr19_-_47922373 0.110 ENST00000559524.1
ENST00000557833.1
ENST00000558555.1
ENST00000561293.1
ENST00000441740.2
MEIS3




Meis homeobox 3




chr9_-_139948468 0.109 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr1_+_110082487 0.108 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr9_-_92051354 0.107 ENST00000418828.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr15_+_68117872 0.107 ENST00000380035.2
ENST00000389002.1
SKOR1

SKI family transcriptional corepressor 1

chr12_-_57871853 0.107 ENST00000549602.1
ENST00000430041.2
ARHGAP9

Rho GTPase activating protein 9

chr9_-_140196703 0.106 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr19_+_10527449 0.106 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr16_-_68406161 0.106 ENST00000568373.1
ENST00000563226.1
SMPD3

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

chr18_+_72922710 0.105 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr11_+_66742742 0.105 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr4_-_186697044 0.104 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr18_+_39739223 0.104 ENST00000601948.1
LINC00907
long intergenic non-protein coding RNA 907

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.2 0.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 0.5 GO:0050894 determination of affect(GO:0050894)
0.2 1.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.5 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.1 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.2 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.1 GO:0060428 lung epithelium development(GO:0060428)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 1.1 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.6 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0002385 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.0 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.0 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.1 GO:0015822 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.1 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.1 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0033007 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.0 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.0 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.1 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) negative regulation of dopamine receptor signaling pathway(GO:0060160) regulation of locomotion involved in locomotory behavior(GO:0090325) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.0 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.0 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.0 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.0 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.5 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.5 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.2 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 1.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.0 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins