Motif ID: SMAD3

Z-value: 0.306


Transcription factors associated with SMAD3:

Gene SymbolEntrez IDGene Name
SMAD3 ENSG00000166949.11 SMAD3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMAD3hg19_v2_chr15_+_67358163_67358192-0.817.5e-03Click!


Activity profile for motif SMAD3.

activity profile for motif SMAD3


Sorted Z-values histogram for motif SMAD3

Sorted Z-values for motif SMAD3



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_46922659 0.380 ENST00000265417.7
 GPR116
G protein-coupled receptor 116
chr6_+_47666275 0.327 ENST00000327753.3
ENST00000283303.2
 GPR115

G protein-coupled receptor 115

chr7_+_139528952 0.311 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
 TBXAS1



thromboxane A synthase 1 (platelet)



chr7_+_139529040 0.291 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
 TBXAS1


thromboxane A synthase 1 (platelet)


chr22_-_36013368 0.291 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
 MB



myoglobin



chr6_-_27782548 0.262 ENST00000333151.3
 HIST1H2AJ
histone cluster 1, H2aj
chrX_-_27999566 0.239 ENST00000441525.1
 DCAF8L1
DDB1 and CUL4 associated factor 8-like 1
chr6_-_27100529 0.233 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
 HIST1H2BJ


histone cluster 1, H2bj


chr6_+_27775899 0.217 ENST00000358739.3
 HIST1H2AI
histone cluster 1, H2ai
chr6_+_27114861 0.178 ENST00000377459.1
 HIST1H2AH
histone cluster 1, H2ah
chr6_+_123038689 0.178 ENST00000354275.2
ENST00000368446.1
 PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr6_-_26285737 0.163 ENST00000377727.1
ENST00000289352.1
 HIST1H4H

histone cluster 1, H4h

chr20_-_23030296 0.156 ENST00000377103.2
 THBD
thrombomodulin
chr13_+_96743093 0.156 ENST00000376705.2
 HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr5_+_140566 0.151 ENST00000502646.1
 PLEKHG4B
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr6_-_27114577 0.151 ENST00000356950.1
ENST00000396891.4
 HIST1H2BK

histone cluster 1, H2bk

chr17_-_39942322 0.143 ENST00000449889.1
ENST00000465293.1
 JUP

junction plakoglobin

chr6_-_27860956 0.141 ENST00000359611.2
 HIST1H2AM
histone cluster 1, H2am
chr1_-_44482979 0.134 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr8_+_22250334 0.134 ENST00000520832.1
 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr6_-_27806117 0.126 ENST00000330180.2
 HIST1H2AK
histone cluster 1, H2ak
chr6_-_26124138 0.109 ENST00000314332.5
ENST00000396984.1
 HIST1H2BC

histone cluster 1, H2bc

chr6_+_26124373 0.108 ENST00000377791.2
ENST00000602637.1
 HIST1H2AC

histone cluster 1, H2ac

chr3_+_69811858 0.101 ENST00000433517.1
 MITF
microphthalmia-associated transcription factor
chr6_+_27806319 0.100 ENST00000606613.1
ENST00000396980.3
 HIST1H2BN

histone cluster 1, H2bn

chr16_+_56703703 0.094 ENST00000332374.4
 MT1H
metallothionein 1H
chr16_+_56703737 0.088 ENST00000569155.1
 MT1H
metallothionein 1H
chr1_-_8877692 0.084 ENST00000400908.2
 RERE
arginine-glutamic acid dipeptide (RE) repeats
chr6_-_26033796 0.082 ENST00000259791.2
 HIST1H2AB
histone cluster 1, H2ab
chr20_-_30311703 0.081 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
 BCL2L1



BCL2-like 1



chr4_+_69917078 0.081 ENST00000502942.1
 UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chrX_-_48931648 0.080 ENST00000376386.3
ENST00000376390.4
 PRAF2

PRA1 domain family, member 2

chr10_-_90712520 0.075 ENST00000224784.6
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_+_204732487 0.075 ENST00000302823.3
 CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr6_+_27861190 0.073 ENST00000303806.4
 HIST1H2BO
histone cluster 1, H2bo
chr14_+_93389425 0.070 ENST00000216492.5
ENST00000334654.4
 CHGA

chromogranin A (parathyroid secretory protein 1)

chr6_+_116937636 0.070 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
 RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr2_-_220110111 0.070 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
 GLB1L



galactosidase, beta 1-like



chrX_+_49832231 0.067 ENST00000376108.3
 CLCN5
chloride channel, voltage-sensitive 5
chr1_-_9189144 0.064 ENST00000414642.2
 GPR157
G protein-coupled receptor 157
chr9_+_136399929 0.063 ENST00000393060.1
 ADAMTSL2
ADAMTS-like 2
chr7_+_141490017 0.062 ENST00000247883.4
 TAS2R5
taste receptor, type 2, member 5
chr8_+_38586068 0.060 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
 TACC1


transforming, acidic coiled-coil containing protein 1


chr6_+_27782788 0.058 ENST00000359465.4
 HIST1H2BM
histone cluster 1, H2bm
chr5_+_52776228 0.058 ENST00000256759.3
 FST
follistatin
chr18_+_77623668 0.057 ENST00000316249.3
 KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr1_-_9189229 0.057 ENST00000377411.4
 GPR157
G protein-coupled receptor 157
chr2_+_28615669 0.057 ENST00000379619.1
ENST00000264716.4
 FOSL2

FOS-like antigen 2

chr5_+_140625147 0.056 ENST00000231173.3
 PCDHB15
protocadherin beta 15
chr6_-_27775694 0.055 ENST00000377401.2
 HIST1H2BL
histone cluster 1, H2bl
chr17_-_34195862 0.055 ENST00000592980.1
ENST00000587626.1
 C17orf66

chromosome 17 open reading frame 66

chr8_+_38585704 0.052 ENST00000519416.1
ENST00000520615.1
 TACC1

transforming, acidic coiled-coil containing protein 1

chr17_-_34195889 0.052 ENST00000311880.2
 C17orf66
chromosome 17 open reading frame 66
chr2_-_220110187 0.051 ENST00000295759.7
ENST00000392089.2
 GLB1L

galactosidase, beta 1-like

chr22_-_36635598 0.051 ENST00000454728.1
 APOL2
apolipoprotein L, 2
chr22_-_36635225 0.051 ENST00000529194.1
 APOL2
apolipoprotein L, 2
chr1_+_149804218 0.050 ENST00000610125.1
 HIST2H4A
histone cluster 2, H4a
chr17_+_78193443 0.050 ENST00000577155.1
 SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr6_-_66417107 0.050 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
 EYS



eyes shut homolog (Drosophila)



chr5_+_140529630 0.050 ENST00000543635.1
 PCDHB6
protocadherin beta 6
chr11_+_35211511 0.049 ENST00000524922.1
 CD44
CD44 molecule (Indian blood group)
chr3_+_190105909 0.048 ENST00000456423.1
 CLDN16
claudin 16
chr2_+_220110177 0.047 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
 STK16


serine/threonine kinase 16


chr1_+_201159914 0.047 ENST00000335211.4
ENST00000451870.2
ENST00000295591.8
 IGFN1


immunoglobulin-like and fibronectin type III domain containing 1


chr17_-_43487741 0.046 ENST00000455881.1
 ARHGAP27
Rho GTPase activating protein 27
chr3_+_126243126 0.045 ENST00000319340.2
 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr19_-_37958086 0.045 ENST00000592490.1
ENST00000392149.2
 ZNF569

zinc finger protein 569

chr22_-_36635563 0.044 ENST00000451256.2
 APOL2
apolipoprotein L, 2
chr5_+_55147205 0.044 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
 IL31RA



interleukin 31 receptor A



chr4_-_39033963 0.044 ENST00000381938.3
 TMEM156
transmembrane protein 156
chr7_-_142247606 0.042 ENST00000390361.3
 TRBV7-3
T cell receptor beta variable 7-3
chr16_+_19098178 0.039 ENST00000568032.1
 RP11-626G11.4
RP11-626G11.4
chr6_+_27100811 0.039 ENST00000359193.2
 HIST1H2AG
histone cluster 1, H2ag
chr17_+_30813576 0.039 ENST00000313401.3
 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_-_52441713 0.038 ENST00000182527.3
 TRAM2
translocation associated membrane protein 2
chr6_+_27791862 0.038 ENST00000355057.1
 HIST1H4J
histone cluster 1, H4j
chr5_-_180242576 0.038 ENST00000514438.1
 MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr18_+_29598335 0.037 ENST00000217740.3
 RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr19_-_42006539 0.037 ENST00000597702.1
ENST00000588495.1
ENST00000595837.1
ENST00000594315.1
 AC011526.1



AC011526.1



chr14_+_91580357 0.036 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
 C14orf159









chromosome 14 open reading frame 159









chr6_-_41888843 0.035 ENST00000434077.1
ENST00000409312.1
 MED20

mediator complex subunit 20

chrX_-_101410762 0.035 ENST00000543160.1
ENST00000333643.3
 BEX5

brain expressed, X-linked 5

chr17_-_73874654 0.034 ENST00000254816.2
 TRIM47
tripartite motif containing 47
chr17_+_36452989 0.034 ENST00000312513.5
ENST00000582535.1
 MRPL45

mitochondrial ribosomal protein L45

chr17_-_26733604 0.034 ENST00000584426.1
ENST00000584995.1
 SLC46A1

solute carrier family 46 (folate transporter), member 1

chr11_+_35222629 0.034 ENST00000526553.1
 CD44
CD44 molecule (Indian blood group)
chr5_-_180242534 0.034 ENST00000333055.3
ENST00000513431.1
 MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chr2_-_128784846 0.033 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
 SAP130


Sin3A-associated protein, 130kDa


chr6_-_41888814 0.032 ENST00000409060.1
ENST00000265350.4
 MED20

mediator complex subunit 20

chr17_-_43487780 0.032 ENST00000532038.1
ENST00000528677.1
 ARHGAP27

Rho GTPase activating protein 27

chr7_-_120497178 0.032 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
 TSPAN12


tetraspanin 12


chr3_+_51741072 0.031 ENST00000395052.3
 GRM2
glutamate receptor, metabotropic 2
chr6_+_26204825 0.030 ENST00000360441.4
 HIST1H4E
histone cluster 1, H4e
chr16_+_30483962 0.030 ENST00000356798.6
 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chrX_-_62571187 0.029 ENST00000335144.3
 SPIN4
spindlin family, member 4
chr22_+_41956767 0.029 ENST00000306149.7
 CSDC2
cold shock domain containing C2, RNA binding
chr16_-_31076273 0.029 ENST00000426488.2
 ZNF668
zinc finger protein 668
chr4_+_55524085 0.029 ENST00000412167.2
ENST00000288135.5
 KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr4_-_177116772 0.029 ENST00000280191.2
 SPATA4
spermatogenesis associated 4
chr5_-_132362226 0.028 ENST00000509437.1
ENST00000355372.2
ENST00000513541.1
ENST00000509008.1
ENST00000513848.1
ENST00000504170.1
ENST00000324170.3
 ZCCHC10






zinc finger, CCHC domain containing 10






chr4_-_157563459 0.026 ENST00000504237.1
ENST00000511399.1
 RP11-171N4.2

Uncharacterized protein

chr1_-_21113765 0.026 ENST00000438032.1
ENST00000424732.1
ENST00000437575.1
 HP1BP3


heterochromatin protein 1, binding protein 3


chrX_-_62571220 0.024 ENST00000374884.2
 SPIN4
spindlin family, member 4
chr4_+_40337340 0.023 ENST00000310169.2
 CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr6_+_30850862 0.023 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
 DDR1


discoidin domain receptor tyrosine kinase 1


chr8_+_10530133 0.022 ENST00000304519.5
 C8orf74
chromosome 8 open reading frame 74
chr12_+_67663056 0.022 ENST00000545606.1
 CAND1
cullin-associated and neddylation-dissociated 1
chr9_-_14322319 0.022 ENST00000606230.1
 NFIB
nuclear factor I/B
chr1_-_160832670 0.021 ENST00000368032.2
 CD244
CD244 molecule, natural killer cell receptor 2B4
chrX_+_47444613 0.020 ENST00000445623.1
 TIMP1
TIMP metallopeptidase inhibitor 1
chr6_+_41888926 0.019 ENST00000230340.4
 BYSL
bystin-like
chr5_+_167913450 0.019 ENST00000231572.3
ENST00000538719.1
 RARS

arginyl-tRNA synthetase

chr17_-_39093672 0.019 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23


keratin 23 (histone deacetylase inducible)


chr14_+_91580777 0.019 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
 C14orf159


chromosome 14 open reading frame 159


chr16_-_3350614 0.018 ENST00000268674.2
 TIGD7
tigger transposable element derived 7
chr6_+_30851205 0.018 ENST00000515881.1
 DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_9129598 0.018 ENST00000535586.1
 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr16_+_30484021 0.018 ENST00000358164.5
 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr2_+_204732666 0.017 ENST00000295854.6
ENST00000472206.1
 CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr19_-_41196458 0.017 ENST00000598779.1
 NUMBL
numb homolog (Drosophila)-like
chr1_-_36906474 0.017 ENST00000433045.2
 OSCP1
organic solute carrier partner 1
chr14_+_91581011 0.017 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
 C14orf159


chromosome 14 open reading frame 159


chr16_+_57847684 0.016 ENST00000335616.2
 CTD-2600O9.1
uncharacterized protein LOC388282
chr6_+_30850697 0.016 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
 DDR1






discoidin domain receptor tyrosine kinase 1






chr12_+_119616447 0.016 ENST00000281938.2
 HSPB8
heat shock 22kDa protein 8
chr16_-_31076332 0.015 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668


zinc finger protein 668


chr6_+_139349903 0.015 ENST00000461027.1
 ABRACL
ABRA C-terminal like
chrX_-_46618490 0.015 ENST00000328306.4
 SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr5_+_122181279 0.015 ENST00000395451.4
ENST00000506996.1
 SNX24

sorting nexin 24

chr14_+_91580732 0.015 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
 C14orf159


chromosome 14 open reading frame 159


chr1_-_9129735 0.014 ENST00000377424.4
 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr16_-_11723066 0.014 ENST00000576036.1
 LITAF
lipopolysaccharide-induced TNF factor
chr4_-_38666430 0.014 ENST00000436901.1
 AC021860.1
Uncharacterized protein
chr19_-_35166604 0.011 ENST00000601241.1
 SCGB2B2
secretoglobin, family 2B, member 2
chr11_-_46142615 0.011 ENST00000529734.1
ENST00000323180.6
 PHF21A

PHD finger protein 21A

chr19_-_13947099 0.010 ENST00000587762.1
 MIR24-2
microRNA 24-2
chr10_-_24911746 0.010 ENST00000320481.6
 ARHGAP21
Rho GTPase activating protein 21
chr12_+_14927270 0.009 ENST00000544848.1
 H2AFJ
H2A histone family, member J
chr5_-_41870621 0.009 ENST00000196371.5
 OXCT1
3-oxoacid CoA transferase 1
chr19_-_50143452 0.008 ENST00000246792.3
 RRAS
related RAS viral (r-ras) oncogene homolog
chr6_-_26027480 0.008 ENST00000377364.3
 HIST1H4B
histone cluster 1, H4b
chr7_+_50348268 0.008 ENST00000438033.1
ENST00000439701.1
 IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr11_+_60869867 0.008 ENST00000347785.3
 CD5
CD5 molecule
chr11_+_57531292 0.007 ENST00000524579.1
 CTNND1
catenin (cadherin-associated protein), delta 1
chr1_+_25757376 0.007 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
 TMEM57


transmembrane protein 57


chr1_-_9129631 0.007 ENST00000377414.3
 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr8_+_145065705 0.007 ENST00000533044.1
 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr15_+_51633826 0.006 ENST00000335449.6
 GLDN
gliomedin
chr14_+_91580708 0.006 ENST00000518868.1
 C14orf159
chromosome 14 open reading frame 159
chr7_+_39125365 0.006 ENST00000559001.1
ENST00000464276.2
 POU6F2

POU class 6 homeobox 2

chr16_-_3306587 0.006 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
 MEFV



Mediterranean fever



chr19_-_42724261 0.006 ENST00000595337.1
 DEDD2
death effector domain containing 2
chr11_-_107729887 0.005 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr18_+_44526786 0.005 ENST00000245121.5
ENST00000356157.7
 KATNAL2

katanin p60 subunit A-like 2

chr9_+_100069933 0.005 ENST00000529487.1
 CCDC180
coiled-coil domain containing 180
chr16_+_30773636 0.004 ENST00000402121.3
ENST00000565995.1
ENST00000563683.1
ENST00000357890.5
ENST00000565931.1
 RNF40




ring finger protein 40, E3 ubiquitin protein ligase




chr18_+_43753500 0.004 ENST00000587591.1
ENST00000588730.1
 C18orf25

chromosome 18 open reading frame 25

chr14_+_102786063 0.004 ENST00000442396.2
ENST00000262236.5
 ZNF839

zinc finger protein 839

chr4_-_103940791 0.004 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
 SLC9B1


solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1


chr19_+_34850385 0.004 ENST00000587521.2
ENST00000587384.1
ENST00000592277.1
 GPI


glucose-6-phosphate isomerase


chr1_+_153190053 0.003 ENST00000368744.3
 PRR9
proline rich 9
chr16_-_58328884 0.003 ENST00000569079.1
 PRSS54
protease, serine, 54
chr14_+_96858433 0.003 ENST00000267584.4
 AK7
adenylate kinase 7
chr16_-_30773372 0.003 ENST00000545825.1
ENST00000541260.1
 C16orf93

chromosome 16 open reading frame 93

chr19_+_36132631 0.002 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
 ETV2



ets variant 2



chr9_-_43133544 0.002 ENST00000254835.2
 ANKRD20A3
ankyrin repeat domain 20 family, member A3
chr11_+_66406149 0.002 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
 RBM4






RNA binding motif protein 4






chr1_-_11042094 0.002 ENST00000377004.4
ENST00000377008.4
 C1orf127

chromosome 1 open reading frame 127

chr8_-_101117847 0.001 ENST00000523287.1
ENST00000519092.1
 RGS22

regulator of G-protein signaling 22

chrX_-_153523462 0.001 ENST00000361930.3
ENST00000369926.1
 TEX28

testis expressed 28

chr1_-_226129083 0.001 ENST00000420304.2
 LEFTY2
left-right determination factor 2
chr11_+_72983246 0.001 ENST00000393590.2
 P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr12_-_110939870 0.001 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
 VPS29




vacuolar protein sorting 29 homolog (S. cerevisiae)




chr11_+_66406088 0.001 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
 RBM4


RNA binding motif protein 4


chr14_+_53196872 0.001 ENST00000442123.2
ENST00000354586.4
 STYX

serine/threonine/tyrosine interacting protein

chr17_-_982198 0.001 ENST00000571945.1
ENST00000536794.2
 ABR

active BCR-related


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1901079 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.0 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends