Motif ID: SMAD1

Z-value: 0.596


Transcription factors associated with SMAD1:

Gene SymbolEntrez IDGene Name
SMAD1 ENSG00000170365.5 SMAD1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMAD1hg19_v2_chr4_+_146402843_146402864-0.353.5e-01Click!


Activity profile for motif SMAD1.

activity profile for motif SMAD1


Sorted Z-values histogram for motif SMAD1

Sorted Z-values for motif SMAD1



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_34117447 0.374 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173



chromosome 20 open reading frame 173



chr19_-_51875894 0.230 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7


natural killer cell group 7 sequence


chr19_-_51587502 0.218 ENST00000156499.2
ENST00000391802.1
KLK14

kallikrein-related peptidase 14

chr2_-_152118276 0.190 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr2_-_67442409 0.174 ENST00000414404.1
ENST00000433133.1
AC078941.1

AC078941.1

chr6_-_28321827 0.172 ENST00000444081.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr8_+_55467072 0.168 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr5_-_147211226 0.168 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr4_-_38807199 0.153 ENST00000508364.1
TLR1
toll-like receptor 1
chr1_+_44401479 0.146 ENST00000438616.3
ARTN
artemin
chr14_-_81916501 0.144 ENST00000555001.1
RP11-299L17.3
RP11-299L17.3
chr22_+_22676808 0.142 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr2_+_128177253 0.139 ENST00000427769.1
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr15_-_44969022 0.139 ENST00000560110.1
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr13_+_111972980 0.132 ENST00000283547.1
TEX29
testis expressed 29
chr19_+_50003781 0.132 ENST00000602157.1
hsa-mir-150
hsa-mir-150
chr16_-_55866997 0.130 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr7_-_3198204 0.127 ENST00000402115.1
ENST00000403226.1
AC091801.1

LOC392621; Uncharacterized protein

chr16_+_58010339 0.123 ENST00000290871.5
ENST00000441824.2
TEPP

testis, prostate and placenta expressed

chrX_+_56644819 0.121 ENST00000446028.1
RP11-431N15.2
RP11-431N15.2
chr6_+_35744367 0.121 ENST00000360454.2
ENST00000403376.3
CLPSL2

colipase-like 2

chr4_-_122872029 0.118 ENST00000502968.1
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr19_+_42381337 0.117 ENST00000597454.1
ENST00000444740.2
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr16_-_1275257 0.117 ENST00000234798.4
TPSG1
tryptase gamma 1
chr7_-_142149390 0.116 ENST00000390372.3
TRBV5-5
T cell receptor beta variable 5-5
chr20_-_30458019 0.112 ENST00000486996.1
ENST00000398084.2
DUSP15

dual specificity phosphatase 15

chr9_-_33402506 0.111 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr1_-_228353112 0.111 ENST00000366713.1
IBA57-AS1
IBA57 antisense RNA 1 (head to head)
chr17_+_76311791 0.110 ENST00000586321.1
AC061992.2
AC061992.2
chr19_-_35981358 0.107 ENST00000484218.2
ENST00000338897.3
KRTDAP

keratinocyte differentiation-associated protein

chr2_+_101223490 0.105 ENST00000414647.1
ENST00000424342.1
AC068538.4

AC068538.4

chr16_-_20587599 0.104 ENST00000566384.1
ENST00000565232.1
ENST00000567001.1
ENST00000565322.1
ENST00000569344.1
ENST00000329697.6
ENST00000414188.2
ENST00000568882.1
ACSM2B







acyl-CoA synthetase medium-chain family member 2B







chr22_-_24641027 0.104 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5




gamma-glutamyltransferase 5




chr19_-_17571722 0.103 ENST00000301944.2
NXNL1
nucleoredoxin-like 1
chr22_+_21133469 0.101 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr19_-_35417716 0.099 ENST00000604333.1
CTC-523E23.8
CTC-523E23.8
chr6_+_41010293 0.097 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2


translocator protein 2


chr8_+_39972170 0.096 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr12_-_13529594 0.096 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr17_+_6658878 0.096 ENST00000574394.1
XAF1
XIAP associated factor 1
chr7_-_229557 0.095 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr21_-_43771226 0.095 ENST00000291526.4
TFF2
trefoil factor 2
chr19_+_42381173 0.095 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr2_+_121493717 0.095 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr12_+_113012831 0.094 ENST00000547686.1
ENST00000543106.2
ENST00000551593.1
ENST00000546426.1
ENST00000551748.1
RPH3A




rabphilin 3A homolog (mouse)




chr6_+_77484663 0.093 ENST00000607287.1
RP11-354K4.2
RP11-354K4.2
chr6_-_33048483 0.093 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr5_+_173763250 0.093 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1


RP11-267A15.1


chr17_-_47925379 0.090 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4




tachykinin 4 (hemokinin)




chr12_-_55042140 0.087 ENST00000293371.6
ENST00000456047.2
DCD

dermcidin

chr1_+_152178320 0.086 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr1_-_153513170 0.083 ENST00000368717.2
S100A5
S100 calcium binding protein A5
chr14_-_46185155 0.083 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr12_+_57388230 0.083 ENST00000300098.1
GPR182
G protein-coupled receptor 182
chr16_+_1306093 0.083 ENST00000211076.3
TPSD1
tryptase delta 1
chr9_+_139846708 0.082 ENST00000371633.3
LCN12
lipocalin 12
chr17_+_38083977 0.081 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4


RP11-387H17.4


chr11_-_7904464 0.081 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5

RP11-35J10.5

chr3_+_45071622 0.081 ENST00000428034.1
CLEC3B
C-type lectin domain family 3, member B
chr17_+_67957878 0.080 ENST00000420427.1
AC004562.1
AC004562.1
chr17_+_2264983 0.080 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr3_-_161090660 0.080 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr12_-_11062161 0.080 ENST00000390677.2
TAS2R13
taste receptor, type 2, member 13
chr4_-_10023095 0.079 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_+_31582961 0.079 ENST00000376059.3
ENST00000337917.7
AIF1

allograft inflammatory factor 1

chr1_-_154167124 0.079 ENST00000515609.1
TPM3
tropomyosin 3
chr19_+_41620335 0.079 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr6_+_33043703 0.079 ENST00000418931.2
ENST00000535465.1
HLA-DPB1

major histocompatibility complex, class II, DP beta 1

chr5_+_127039075 0.078 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr19_-_54824344 0.078 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr17_+_34639793 0.077 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2


chemokine (C-C motif) ligand 4-like 2


chr6_+_168434678 0.076 ENST00000496008.1
KIF25
kinesin family member 25
chr19_+_17638059 0.076 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C



family with sequence similarity 129, member C



chr3_-_53878644 0.076 ENST00000481668.1
ENST00000467802.1
CHDH

choline dehydrogenase

chr20_+_1184098 0.075 ENST00000400633.1
C20orf202
chromosome 20 open reading frame 202
chr11_+_64004888 0.075 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr5_-_99870932 0.075 ENST00000504833.1
CTD-2001C12.1
CTD-2001C12.1
chr5_+_137419581 0.075 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
WNT8A


wingless-type MMTV integration site family, member 8A


chr1_+_32712815 0.075 ENST00000373582.3
FAM167B
family with sequence similarity 167, member B
chr11_-_299519 0.075 ENST00000382614.2
IFITM5
interferon induced transmembrane protein 5
chr5_-_149516966 0.074 ENST00000517957.1
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr4_+_46995726 0.074 ENST00000513567.1
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr19_-_43690642 0.073 ENST00000407356.1
ENST00000407568.1
ENST00000404580.1
ENST00000599812.1
PSG5



pregnancy specific beta-1-glycoprotein 5



chr5_+_118965244 0.073 ENST00000515256.1
ENST00000509264.1
FAM170A

family with sequence similarity 170, member A

chr3_+_38307293 0.073 ENST00000311856.4
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr17_-_39258461 0.072 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr15_+_47631257 0.072 ENST00000560636.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr12_+_6419877 0.072 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr19_-_9226439 0.072 ENST00000293614.1
ENST00000541538.1
OR7G1

olfactory receptor, family 7, subfamily G, member 1

chr16_+_20462783 0.072 ENST00000574251.1
ENST00000576361.1
ENST00000417235.2
ENST00000573854.1
ENST00000424070.1
ENST00000536134.1
ENST00000219054.6
ENST00000575690.1
ENST00000571894.1
ACSM2A








acyl-CoA synthetase medium-chain family member 2A








chr6_+_33551515 0.071 ENST00000374458.1
GGNBP1
gametogenetin binding protein 1 (pseudogene)
chr2_+_232575168 0.071 ENST00000440384.1
PTMA
prothymosin, alpha
chr10_-_105218645 0.071 ENST00000329905.5
CALHM1
calcium homeostasis modulator 1
chr18_+_70536215 0.071 ENST00000578967.1
RP11-676J15.1
RP11-676J15.1
chr3_+_193965426 0.071 ENST00000455821.1
RP11-513G11.3
RP11-513G11.3
chr16_+_69985644 0.071 ENST00000561889.1
CLEC18A
C-type lectin domain family 18, member A
chr9_-_139637355 0.071 ENST00000474369.1
ENST00000497771.1
ENST00000527229.1
LCN10


lipocalin 10


chr12_-_57443886 0.071 ENST00000300119.3
MYO1A
myosin IA
chr16_+_2521500 0.070 ENST00000293973.1
NTN3
netrin 3
chr17_-_46799872 0.070 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr5_+_20616500 0.070 ENST00000512688.1
RP11-774D14.1
RP11-774D14.1
chr10_+_81370689 0.070 ENST00000372308.3
ENST00000398636.3
ENST00000428376.2
ENST00000372313.5
ENST00000419470.2
ENST00000429958.1
ENST00000439264.1
SFTPA1






surfactant protein A1






chrX_+_152760397 0.070 ENST00000331595.4
ENST00000431891.1
BGN

biglycan

chr11_-_17410629 0.070 ENST00000526912.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr17_+_7323634 0.069 ENST00000323675.3
SPEM1
spermatid maturation 1
chr14_-_98444438 0.069 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chrX_-_139866723 0.068 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr9_+_117085336 0.068 ENST00000259396.8
ENST00000538816.1
ORM1

orosomucoid 1

chr10_-_25304889 0.068 ENST00000483339.2
ENKUR
enkurin, TRPC channel interacting protein
chr10_+_82116529 0.068 ENST00000411538.1
ENST00000256039.2
DYDC2

DPY30 domain containing 2

chr5_+_78407602 0.068 ENST00000274353.5
ENST00000524080.1
BHMT

betaine--homocysteine S-methyltransferase

chr16_+_81272287 0.067 ENST00000425577.2
ENST00000564552.1
BCMO1

beta-carotene 15,15'-monooxygenase 1

chr15_+_76016293 0.066 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr16_+_1306060 0.066 ENST00000397534.2
TPSD1
tryptase delta 1
chr13_+_108921977 0.066 ENST00000430559.1
ENST00000375887.4
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr19_-_17622269 0.066 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chrX_-_5644225 0.066 ENST00000422914.1
RP11-733O18.1
RP11-733O18.1
chr11_-_8739383 0.066 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr9_+_19408919 0.065 ENST00000380376.1
ACER2
alkaline ceramidase 2
chr10_+_115511434 0.065 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr15_+_84908573 0.065 ENST00000424966.1
ENST00000422563.2
GOLGA6L4

golgin A6 family-like 4

chr12_-_122658746 0.065 ENST00000377035.1
IL31
interleukin 31
chr10_-_44880491 0.065 ENST00000374426.2
ENST00000395795.4
ENST00000395794.2
ENST00000374429.2
ENST00000395793.3
ENST00000343575.6
CXCL12





chemokine (C-X-C motif) ligand 12





chrX_-_63450480 0.064 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr6_-_35992270 0.064 ENST00000394602.2
ENST00000355574.2
SLC26A8

solute carrier family 26 (anion exchanger), member 8

chr8_+_49984894 0.064 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
C8orf22


chromosome 8 open reading frame 22


chr19_+_51273721 0.064 ENST00000270590.4
GPR32
G protein-coupled receptor 32
chr10_-_122740205 0.064 ENST00000414774.1
RP11-95I16.2
RP11-95I16.2
chr19_-_3479086 0.064 ENST00000587847.1
C19orf77
chromosome 19 open reading frame 77
chr17_+_33474826 0.064 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B


unc-45 homolog B (C. elegans)


chr19_-_19373601 0.064 ENST00000291481.7
HAPLN4
hyaluronan and proteoglycan link protein 4
chr2_+_30455016 0.063 ENST00000401506.1
ENST00000407930.2
LBH

limb bud and heart development

chr10_-_69597810 0.063 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr14_-_47120956 0.063 ENST00000298283.3
RPL10L
ribosomal protein L10-like
chr19_+_37096194 0.063 ENST00000460670.1
ENST00000292928.2
ENST00000439428.1
ZNF382


zinc finger protein 382


chr9_+_74729511 0.063 ENST00000545168.1
GDA
guanine deaminase
chr10_+_37414785 0.063 ENST00000374660.1
ENST00000602533.1
ENST00000361713.1
ANKRD30A


ankyrin repeat domain 30A


chr3_+_99904531 0.063 ENST00000429523.2
ENST00000476804.1
TMEM30C

transmembrane protein 30C

chr11_-_111649015 0.062 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr17_-_19281203 0.062 ENST00000487415.2
B9D1
B9 protein domain 1
chr7_+_100187196 0.061 ENST00000468962.1
ENST00000427939.2
FBXO24

F-box protein 24

chr13_+_25338290 0.061 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
RNF17


ring finger protein 17


chr22_-_41636892 0.061 ENST00000455425.1
CHADL
chondroadherin-like
chr22_+_18593097 0.061 ENST00000426208.1
TUBA8
tubulin, alpha 8
chr20_+_34679725 0.060 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_+_7559485 0.060 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_87017948 0.060 ENST00000409781.1
CD8A
CD8a molecule
chr1_-_159880159 0.060 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr1_-_226129083 0.059 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr19_-_51289436 0.059 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr19_+_19639704 0.059 ENST00000514277.4
YJEFN3
YjeF N-terminal domain containing 3
chr21_+_36041688 0.059 ENST00000360731.3
ENST00000349499.2
CLIC6

chloride intracellular channel 6

chr10_-_81270678 0.059 ENST00000538322.1
AL133481.1
Uncharacterized protein
chr2_-_165812028 0.058 ENST00000303735.4
SLC38A11
solute carrier family 38, member 11
chr20_-_30458432 0.058 ENST00000375966.4
ENST00000278979.3
DUSP15

dual specificity phosphatase 15

chr3_-_58643483 0.058 ENST00000483787.1
FAM3D
family with sequence similarity 3, member D
chr8_-_33455268 0.058 ENST00000522982.1
DUSP26
dual specificity phosphatase 26 (putative)
chr4_+_106816592 0.058 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT




nephronectin




chr8_+_19536083 0.058 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr2_-_158345341 0.058 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr19_-_54804173 0.057 ENST00000391744.3
ENST00000251390.3
LILRA3

leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

chr9_-_116840728 0.057 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr7_-_99277610 0.056 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr17_+_35732955 0.056 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr19_-_51523275 0.056 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr17_-_19648916 0.056 ENST00000444455.1
ENST00000439102.2
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr8_-_30002179 0.056 ENST00000320542.3
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr11_+_47608198 0.056 ENST00000356737.2
ENST00000538490.1
FAM180B

family with sequence similarity 180, member B

chr21_+_34804479 0.056 ENST00000421802.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr13_+_108922228 0.056 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr12_-_24715376 0.056 ENST00000446891.2
ENST00000429944.2
RP11-444D3.1

RP11-444D3.1

chr1_+_236557569 0.055 ENST00000334232.4
EDARADD
EDAR-associated death domain
chr5_+_34839260 0.055 ENST00000505624.1
TTC23L
tetratricopeptide repeat domain 23-like
chr7_-_94953878 0.055 ENST00000222381.3
PON1
paraoxonase 1
chr15_-_44969086 0.055 ENST00000434130.1
ENST00000560780.1
PATL2

protein associated with topoisomerase II homolog 2 (yeast)

chr6_-_32784687 0.055 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr1_-_156828810 0.055 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr21_-_35884573 0.055 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr6_-_88875628 0.055 ENST00000551417.1
CNR1
cannabinoid receptor 1 (brain)
chr11_+_71276609 0.054 ENST00000398531.1
ENST00000376536.4
KRTAP5-10

keratin associated protein 5-10

chr4_+_147145709 0.054 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr2_+_29001711 0.054 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_-_52488048 0.053 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr17_+_34058639 0.053 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr17_-_75878647 0.053 ENST00000374983.2
FLJ45079
FLJ45079
chr16_-_55867146 0.053 ENST00000422046.2
CES1
carboxylesterase 1
chr1_+_47137445 0.053 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38


testis expressed 38


chr6_-_26108355 0.052 ENST00000338379.4
HIST1H1T
histone cluster 1, H1t
chr11_+_1151573 0.052 ENST00000534821.1
ENST00000356191.2
MUC5AC

mucin 5AC, oligomeric mucus/gel-forming

chr1_-_152539248 0.052 ENST00000368789.1
LCE3E
late cornified envelope 3E
chr1_+_160160346 0.052 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr4_-_1202611 0.052 ENST00000511679.1
SPON2
spondin 2, extracellular matrix protein
chr10_+_88780049 0.051 ENST00000343959.4
FAM25A
family with sequence similarity 25, member A
chr4_-_15939963 0.051 ENST00000259988.2
FGFBP1
fibroblast growth factor binding protein 1
chr4_-_16077741 0.051 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1


prominin 1


chr11_+_18194384 0.051 ENST00000314254.3
MRGPRX4
MAS-related GPR, member X4
chr19_+_19639670 0.050 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr10_+_63422695 0.050 ENST00000330194.2
ENST00000389639.3
C10orf107

chromosome 10 open reading frame 107

chr22_-_37880543 0.050 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_-_33048503 0.050 ENST00000453337.1
ENST00000417724.1
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.2 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0044010 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.0 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.0 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.0 0.2 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.0 0.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.0 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.0 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.0 0.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.0 GO:0048754 branching morphogenesis of an epithelial tube(GO:0048754)
0.0 0.0 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.0 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0090025 regulation of monocyte chemotaxis(GO:0090025)
0.0 0.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.0 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.0 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.0 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.0 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.0 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins