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• Mean activities
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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: SIX4

Z-value: 0.232

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_5364809	0.149	ENST00000300773.2	OR51B5	olfactory receptor, family 51, subfamily B, member 5
chr3_-_52488048	0.106	ENST00000232975.3	TNNC1	troponin C type 1 (slow)
chr1_+_156611704	0.088	ENST00000329117.5	BCAN	brevican
chr19_-_47128294	0.076	ENST00000596260.1 ENST00000597185.1 ENST00000598865.1 ENST00000594275.1 ENST00000291294.2	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)
chr3_-_69249863	0.061	ENST00000478263.1 ENST00000462512.1	FRMD4B	FERM domain containing 4B
chr11_+_7273181	0.057	ENST00000318881.6	SYT9	synaptotagmin IX
chr12_+_43086018	0.055	ENST00000550177.1	RP11-25I15.3	RP11-25I15.3
chr5_-_78365437	0.055	ENST00000380311.4 ENST00000540686.1 ENST00000255189.3	DMGDH	dimethylglycine dehydrogenase
chr1_-_114414316	0.053	ENST00000528414.1 ENST00000538253.1 ENST00000460620.1 ENST00000420377.2 ENST00000525799.1 ENST00000359785.5	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr22_-_30960876	0.053	ENST00000401975.1 ENST00000428682.1 ENST00000423299.1	GAL3ST1	galactose-3-O-sulfotransferase 1
chr1_+_156611900	0.047	ENST00000457777.2 ENST00000424639.1	BCAN	brevican
chr10_+_88414338	0.046	ENST00000241891.5 ENST00000443292.1	OPN4	opsin 4
chr14_-_67981870	0.045	ENST00000555994.1	TMEM229B	transmembrane protein 229B
chr4_-_176828307	0.045	ENST00000513365.1 ENST00000513667.1 ENST00000503563.1	GPM6A	glycoprotein M6A
chr17_-_18547731	0.040	ENST00000575220.1 ENST00000405044.1 ENST00000572213.1 ENST00000573652.1	TBC1D28	TBC1 domain family, member 28
chr1_-_152196669	0.040	ENST00000368801.2	HRNR	hornerin
chr8_-_123139423	0.039	ENST00000523792.1	RP11-398G24.2	RP11-398G24.2
chr7_-_111428957	0.038	ENST00000417165.1	DOCK4	dedicator of cytokinesis 4
chr19_-_474880	0.038	ENST00000382696.3 ENST00000315489.4	ODF3L2	outer dense fiber of sperm tails 3-like 2
chr2_+_74710194	0.038	ENST00000410003.1 ENST00000442235.2 ENST00000233623.5	TTC31	tetratricopeptide repeat domain 31
chrX_+_56100757	0.037	ENST00000433279.1	AL353698.1	Uncharacterized protein
chr10_+_88414298	0.037	ENST00000372071.2	OPN4	opsin 4
chr1_-_32264356	0.036	ENST00000452755.2	SPOCD1	SPOC domain containing 1
chr3_+_11267691	0.036	ENST00000413416.1	HRH1	histamine receptor H1
chr16_+_640201	0.034	ENST00000563109.1	RAB40C	RAB40C, member RAS oncogene family
chr13_+_33160553	0.030	ENST00000315596.10	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr1_+_156611960	0.029	ENST00000361588.5	BCAN	brevican
chr1_-_32264250	0.027	ENST00000528579.1	SPOCD1	SPOC domain containing 1
chr9_-_95298254	0.027	ENST00000444490.2	ECM2	extracellular matrix protein 2, female organ and adipocyte specific
chr5_+_149569520	0.026	ENST00000230671.2 ENST00000524041.1	SLC6A7	solute carrier family 6 (neurotransmitter transporter), member 7
chr2_-_61244308	0.026	ENST00000407787.1 ENST00000398658.2	PUS10	pseudouridylate synthase 10
chr14_-_67981916	0.024	ENST00000357461.2	TMEM229B	transmembrane protein 229B
chr12_-_4488872	0.023	ENST00000237837.1	FGF23	fibroblast growth factor 23
chr12_+_4714145	0.023	ENST00000545342.1	DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr19_+_13134772	0.022	ENST00000587760.1 ENST00000585575.1	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_11466167	0.021	ENST00000591608.1	DKFZP761J1410	Lipid phosphate phosphatase-related protein type 2
chr3_-_46777911	0.021	ENST00000463091.2	PRSS46	protease, serine, 46
chrX_+_70503037	0.020	ENST00000535149.1	NONO	non-POU domain containing, octamer-binding
chr17_+_15635561	0.019	ENST00000584301.1 ENST00000580596.1 ENST00000464963.1 ENST00000437605.2 ENST00000579428.1	TBC1D26	TBC1 domain family, member 26
chr12_-_10282742	0.019	ENST00000298523.5 ENST00000396484.2 ENST00000310002.4	CLEC7A	C-type lectin domain family 7, member A
chr12_-_58135903	0.018	ENST00000257897.3	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr9_+_132427883	0.017	ENST00000372469.4	PRRX2	paired related homeobox 2
chr1_-_207119738	0.017	ENST00000356495.4	PIGR	polymeric immunoglobulin receptor
chr9_-_95298314	0.017	ENST00000344604.5 ENST00000375540.1	ECM2	extracellular matrix protein 2, female organ and adipocyte specific
chr3_+_32726620	0.016	ENST00000331889.6 ENST00000328834.5	CNOT10	CCR4-NOT transcription complex, subunit 10
chr12_+_8975061	0.016	ENST00000299698.7	A2ML1	alpha-2-macroglobulin-like 1
chr1_+_226250379	0.015	ENST00000366815.3 ENST00000366814.3	H3F3A	H3 histone, family 3A
chr15_+_59279851	0.015	ENST00000348370.4 ENST00000434298.1 ENST00000559160.1	RNF111	ring finger protein 111
chr6_+_1080164	0.014	ENST00000314040.1	AL033381.1	Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chrY_+_22737678	0.014	ENST00000382772.3	EIF1AY	eukaryotic translation initiation factor 1A, Y-linked
chr7_-_14880892	0.013	ENST00000406247.3 ENST00000399322.3 ENST00000258767.5	DGKB	diacylglycerol kinase, beta 90kDa
chr1_+_38022572	0.013	ENST00000541606.1	DNALI1	dynein, axonemal, light intermediate chain 1
chr1_+_8378140	0.012	ENST00000377479.2	SLC45A1	solute carrier family 45, member 1
chr19_+_11466062	0.012	ENST00000251473.5 ENST00000591329.1 ENST00000586380.1	DKFZP761J1410	Lipid phosphate phosphatase-related protein type 2
chr11_+_46958248	0.012	ENST00000536126.1 ENST00000278460.7 ENST00000378618.2 ENST00000395460.2 ENST00000378615.3 ENST00000543718.1	C11orf49	chromosome 11 open reading frame 49
chr10_+_50507232	0.012	ENST00000374144.3	C10orf71	chromosome 10 open reading frame 71
chr19_+_30414551	0.011	ENST00000360605.4 ENST00000570564.1 ENST00000574233.1 ENST00000585655.1	URI1	URI1, prefoldin-like chaperone
chr1_+_149239529	0.011	ENST00000457216.2	RP11-403I13.4	RP11-403I13.4
chr14_-_92413353	0.011	ENST00000556154.1	FBLN5	fibulin 5
chr2_-_74710078	0.011	ENST00000290418.4	CCDC142	coiled-coil domain containing 142
chr19_+_13135386	0.011	ENST00000360105.4 ENST00000588228.1 ENST00000591028.1	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_2906979	0.010	ENST00000380725.1 ENST00000313407.6 ENST00000430149.2 ENST00000440480.2 ENST00000414822.3	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr1_-_173176452	0.010	ENST00000281834.3	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr4_-_170897045	0.010	ENST00000508313.1	RP11-205M3.3	RP11-205M3.3
chr14_-_94984181	0.010	ENST00000341228.2	SERPINA12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr10_+_102759045	0.010	ENST00000370220.1	LZTS2	leucine zipper, putative tumor suppressor 2
chr6_-_76072719	0.009	ENST00000370020.1	FILIP1	filamin A interacting protein 1
chr1_-_42800614	0.009	ENST00000372572.1	FOXJ3	forkhead box J3
chr1_+_231473743	0.009	ENST00000295050.7	SPRTN	SprT-like N-terminal domain
chrX_-_152160740	0.009	ENST00000361887.5 ENST00000439251.1 ENST00000452693.1	PNMA5	paraneoplastic Ma antigen family member 5
chr8_+_144295067	0.009	ENST00000330824.2	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr12_+_133758115	0.008	ENST00000541009.2 ENST00000592241.1	ZNF268	zinc finger protein 268
chr19_+_50887585	0.008	ENST00000440232.2 ENST00000601098.1 ENST00000599857.1 ENST00000593887.1	POLD1	polymerase (DNA directed), delta 1, catalytic subunit
chr1_-_42800860	0.008	ENST00000445886.1 ENST00000361346.1 ENST00000361776.1	FOXJ3	forkhead box J3
chr7_+_69064300	0.008	ENST00000342771.4	AUTS2	autism susceptibility candidate 2
chr11_-_113644491	0.008	ENST00000200135.3	ZW10	zw10 kinetochore protein
chr11_-_46615498	0.008	ENST00000533727.1 ENST00000534300.1 ENST00000528950.1 ENST00000526606.1	AMBRA1	autophagy/beclin-1 regulator 1
chr1_-_42801540	0.007	ENST00000372573.1	FOXJ3	forkhead box J3
chr3_+_32147997	0.007	ENST00000282541.5	GPD1L	glycerol-3-phosphate dehydrogenase 1-like
chr6_+_53794780	0.007	ENST00000505762.1 ENST00000511369.1 ENST00000431554.2	MLIP RP11-411K7.1	muscular LMNA-interacting protein RP11-411K7.1
chr16_-_15180257	0.006	ENST00000540462.1	RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr11_+_34073195	0.006	ENST00000341394.4	CAPRIN1	cell cycle associated protein 1
chr22_+_37318082	0.006	ENST00000406230.1	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr11_-_130184555	0.006	ENST00000525842.1	ZBTB44	zinc finger and BTB domain containing 44
chr1_+_231473990	0.006	ENST00000008440.9	SPRTN	SprT-like N-terminal domain
chr17_+_7465216	0.006	ENST00000321337.7	SENP3	SUMO1/sentrin/SMT3 specific peptidase 3
chr1_-_247335269	0.005	ENST00000543802.2 ENST00000491356.1 ENST00000472531.1 ENST00000340684.6	ZNF124	zinc finger protein 124
chr12_+_133757995	0.005	ENST00000536435.2 ENST00000228289.5 ENST00000541211.2 ENST00000500625.3 ENST00000539248.2 ENST00000542711.2 ENST00000536899.2 ENST00000542986.2 ENST00000537565.1 ENST00000541975.2	ZNF268	zinc finger protein 268
chr22_-_39268308	0.005	ENST00000407418.3	CBX6	chromobox homolog 6
chr1_+_35734616	0.005	ENST00000441447.1	ZMYM4	zinc finger, MYM-type 4
chr5_+_179135246	0.005	ENST00000508787.1	CANX	calnexin
chr11_+_34073269	0.005	ENST00000389645.3	CAPRIN1	cell cycle associated protein 1
chrY_+_22737604	0.005	ENST00000361365.2	EIF1AY	eukaryotic translation initiation factor 1A, Y-linked
chr11_+_117947724	0.005	ENST00000534111.1	TMPRSS4	transmembrane protease, serine 4
chr3_-_49158218	0.005	ENST00000417901.1 ENST00000306026.5 ENST00000434032.2	USP19	ubiquitin specific peptidase 19
chr11_+_125462690	0.005	ENST00000392708.4 ENST00000529196.1 ENST00000531491.1	STT3A	STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr20_-_52687030	0.005	ENST00000411563.1	BCAS1	breast carcinoma amplified sequence 1
chr8_+_95907993	0.004	ENST00000523378.1	NDUFAF6	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr11_-_35547572	0.004	ENST00000378880.2	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr11_-_130184470	0.004	ENST00000357899.4 ENST00000397753.1	ZBTB44	zinc finger and BTB domain containing 44
chr11_+_2415061	0.004	ENST00000481687.1	CD81	CD81 molecule
chr19_-_58892389	0.003	ENST00000427624.2 ENST00000597582.1	ZNF837	zinc finger protein 837
chrX_-_110655391	0.003	ENST00000356915.2 ENST00000356220.3	DCX	doublecortin
chr10_+_7860460	0.003	ENST00000344293.5	TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr10_+_89622870	0.003	ENST00000371953.3	PTEN	phosphatase and tensin homolog
chr22_-_39268192	0.003	ENST00000216083.6	CBX6	chromobox homolog 6
chr12_+_4829507	0.003	ENST00000252318.2	GALNT8	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr14_+_21510385	0.003	ENST00000298690.4	RNASE7	ribonuclease, RNase A family, 7
chr1_+_26737292	0.003	ENST00000254231.4	LIN28A	lin-28 homolog A (C. elegans)
chr11_+_117049910	0.003	ENST00000431081.2 ENST00000524842.1	SIDT2	SID1 transmembrane family, member 2
chr12_-_10282836	0.002	ENST00000304084.8 ENST00000353231.5 ENST00000525605.1	CLEC7A	C-type lectin domain family 7, member A
chr19_+_50270219	0.002	ENST00000354293.5 ENST00000359032.5	AP2A1	adaptor-related protein complex 2, alpha 1 subunit
chr2_+_101223490	0.002	ENST00000414647.1 ENST00000424342.1	AC068538.4	AC068538.4
chr11_+_117049854	0.002	ENST00000278951.7	SIDT2	SID1 transmembrane family, member 2
chr1_-_231473578	0.002	ENST00000360394.2 ENST00000366645.1	EXOC8	exocyst complex component 8
chr1_+_26737253	0.002	ENST00000326279.6	LIN28A	lin-28 homolog A (C. elegans)
chr2_-_169104651	0.001	ENST00000355999.4	STK39	serine threonine kinase 39
chrX_+_108780347	0.001	ENST00000372103.1	NXT2	nuclear transport factor 2-like export factor 2
chr10_+_26505594	0.001	ENST00000259271.3	GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr7_-_99063769	0.001	ENST00000430982.1 ENST00000555673.1 ENST00000394186.3 ENST00000359832.4 ENST00000449683.1 ENST00000488775.1 ENST00000523680.1 ENST00000292475.3 ENST00000413834.1	PTCD1 ATP5J2 ATP5J2-PTCD1	pentatricopeptide repeat domain 1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 ATP5J2-PTCD1 readthrough
chr17_+_56232494	0.001	ENST00000268912.5	OR4D1	olfactory receptor, family 4, subfamily D, member 1
chr7_+_2687173	0.001	ENST00000403167.1	TTYH3	tweety family member 3
chr11_+_117049445	0.001	ENST00000324225.4 ENST00000532960.1	SIDT2	SID1 transmembrane family, member 2
chrX_+_48687283	0.000	ENST00000338270.1	ERAS	ES cell expressed Ras
chr1_-_78148324	0.000	ENST00000370801.3 ENST00000433749.1	ZZZ3	zinc finger, ZZ-type containing 3

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
0.0	0.1	GO:1902523	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:1990584	cardiac Troponin complex(GO:1990584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0046997	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)

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