Motif ID: SHOX2_HOXC5

Z-value: 0.627

Transcription factors associated with SHOX2_HOXC5:

Gene SymbolEntrez IDGene Name
HOXC5 ENSG00000172789.3 HOXC5
SHOX2 ENSG00000168779.15 SHOX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXC5hg19_v2_chr12_+_54426637_544266370.646.1e-02Click!
SHOX2hg19_v2_chr3_-_157823839_157824078-0.127.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of SHOX2_HOXC5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46742630 1.607 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_56270380 1.238 ENST00000434937.2
RFPL4A
ret finger protein-like 4A
chr4_-_70653673 0.880 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr11_-_5323226 0.834 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr5_-_147286065 0.754 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chrX_-_92928557 0.747 ENST00000373079.3
ENST00000475430.2
NAP1L3

nucleosome assembly protein 1-like 3

chr22_-_32766972 0.652 ENST00000382084.4
ENST00000382086.2
RFPL3S

RFPL3 antisense

chr11_-_33913708 0.605 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr14_-_80697396 0.558 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr11_-_7698453 0.524 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr22_-_32651326 0.524 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr21_-_15918618 0.512 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr6_+_127898312 0.508 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr2_+_90248739 0.508 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr14_+_100532771 0.478 ENST00000557153.1
EVL
Enah/Vasp-like
chr8_+_105235572 0.451 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr3_-_165555200 0.439 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr19_+_56280507 0.430 ENST00000341750.4
RFPL4AL1
ret finger protein-like 4A-like 1
chr3_-_157217328 0.423 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr6_+_13272904 0.417 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr6_-_138866823 0.413 ENST00000342260.5
NHSL1
NHS-like 1
chr6_+_78400375 0.400 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr12_-_43833515 0.387 ENST00000549670.1
ENST00000395541.2
ADAMTS20

ADAM metallopeptidase with thrombospondin type 1 motif, 20

chr2_+_128293323 0.384 ENST00000389524.4
ENST00000428314.1
MYO7B

myosin VIIB

chr1_-_114414316 0.375 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22





protein tyrosine phosphatase, non-receptor type 22 (lymphoid)





chr16_+_77756399 0.367 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7




nudix (nucleoside diphosphate linked moiety X)-type motif 7




chr7_-_44122063 0.363 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr5_-_22853429 0.362 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr6_-_170151603 0.361 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr21_-_19858196 0.360 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr13_+_77522632 0.360 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr15_+_48483736 0.356 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr3_+_138340049 0.352 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr6_-_130182410 0.349 ENST00000368143.1
TMEM244
transmembrane protein 244
chrX_+_37639302 0.348 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr6_-_133035185 0.344 ENST00000367928.4
VNN1
vanin 1
chr4_+_183164574 0.344 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr2_-_70352421 0.342 ENST00000414141.1
AC016700.5
AC016700.5
chr17_-_38821373 0.342 ENST00000394052.3
KRT222
keratin 222
chr8_+_39972170 0.340 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr3_+_82035289 0.331 ENST00000470263.1
ENST00000494340.1
RP11-260O18.1

RP11-260O18.1

chr19_-_36001113 0.329 ENST00000434389.1
DMKN
dermokine
chr1_-_150738261 0.324 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr7_-_99277610 0.320 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chrX_+_51486481 0.316 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr22_-_32767017 0.314 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr8_-_7287870 0.309 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr4_+_183370146 0.304 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr8_-_83589388 0.302 ENST00000522776.1
RP11-653B10.1
RP11-653B10.1
chr12_-_15038779 0.298 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr13_-_86373536 0.296 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_155011483 0.284 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr2_+_29001711 0.282 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr19_-_39826639 0.282 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr1_+_16083154 0.279 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr4_-_136809245 0.274 ENST00000504365.1
LINC00613
long intergenic non-protein coding RNA 613
chr5_-_10761206 0.268 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr6_-_138833630 0.267 ENST00000533765.1
NHSL1
NHS-like 1
chr4_-_186570679 0.265 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr12_-_10978957 0.265 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr18_+_47087055 0.263 ENST00000577628.1
LIPG
lipase, endothelial
chr2_+_89952792 0.260 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr11_-_26744908 0.257 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr3_-_151034734 0.255 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr11_+_92085262 0.251 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3


FAT atypical cadherin 3


chr1_+_76540386 0.251 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr1_+_47533160 0.249 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chrX_+_16668278 0.246 ENST00000380200.3
S100G
S100 calcium binding protein G
chr2_+_74648848 0.236 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr4_+_9446156 0.234 ENST00000334879.1
DEFB131
defensin, beta 131
chr6_-_87804815 0.233 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr7_+_134528635 0.230 ENST00000445569.2
CALD1
caldesmon 1
chr19_-_55677999 0.230 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr14_-_25479811 0.229 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr3_+_111717600 0.229 ENST00000273368.4
TAGLN3
transgelin 3
chr1_-_152196669 0.228 ENST00000368801.2
HRNR
hornerin
chr1_-_92952433 0.227 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr15_-_78913628 0.225 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chrX_+_55246771 0.224 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chr19_-_55677920 0.224 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr19_+_41281416 0.222 ENST00000597140.1
MIA
melanoma inhibitory activity
chr2_-_74618907 0.222 ENST00000421392.1
ENST00000437375.1
DCTN1

dynactin 1

chr7_+_120628731 0.220 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr6_+_116601265 0.219 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr11_-_26593779 0.219 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr19_+_54466179 0.219 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr11_-_18956556 0.217 ENST00000302797.3
MRGPRX1
MAS-related GPR, member X1
chr3_-_20053741 0.216 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr19_+_51728316 0.215 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr12_-_22063787 0.213 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr3_-_149095652 0.211 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr14_-_94942577 0.210 ENST00000424550.2
ENST00000337425.5
ENST00000546329.1
SERPINA9


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9


chr7_+_150020329 0.209 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr6_+_160542870 0.207 ENST00000324965.4
ENST00000457470.2
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr12_-_48164812 0.204 ENST00000549151.1
ENST00000548919.1
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chrX_-_9734004 0.203 ENST00000467482.1
ENST00000380929.2
GPR143

G protein-coupled receptor 143

chr11_-_26593677 0.202 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr17_+_67759813 0.201 ENST00000587241.1
AC003051.1
AC003051.1
chr3_+_111630451 0.201 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_+_20963632 0.198 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr3_+_111717511 0.193 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chrX_-_138790348 0.192 ENST00000414978.1
ENST00000519895.1
MCF2

MCF.2 cell line derived transforming sequence

chr2_-_227050079 0.191 ENST00000423838.1
AC068138.1
AC068138.1
chr9_-_75488984 0.191 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1


RP11-151D14.1


chr6_+_161123270 0.191 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr19_-_51327034 0.189 ENST00000301420.2
ENST00000448701.2
KLK1

kallikrein 1

chr11_-_26588634 0.185 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr6_+_151662815 0.184 ENST00000359755.5
AKAP12
A kinase (PRKA) anchor protein 12
chr1_+_146714291 0.184 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L



chromodomain helicase DNA binding protein 1-like



chr3_+_138340067 0.184 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr12_+_20963647 0.183 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr18_+_47087390 0.182 ENST00000583083.1
LIPG
lipase, endothelial
chr12_-_95510743 0.182 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr5_+_140514782 0.179 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr5_-_9630463 0.179 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr1_-_197115818 0.178 ENST00000367409.4
ENST00000294732.7
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr2_-_74618964 0.178 ENST00000417090.1
ENST00000409868.1
DCTN1

dynactin 1

chr14_-_20801427 0.177 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1


cyclin B1 interacting protein 1, E3 ubiquitin protein ligase


chr18_+_61445205 0.176 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr16_-_1538765 0.175 ENST00000447419.2
ENST00000440447.2
PTX4

pentraxin 4, long

chr20_+_15177480 0.174 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr12_+_51984657 0.173 ENST00000550891.1
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr11_-_26593649 0.173 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr6_+_160542821 0.171 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr12_+_8849773 0.171 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr15_+_75303993 0.168 ENST00000564779.1
SCAMP5
secretory carrier membrane protein 5
chrX_+_135230712 0.166 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr3_-_48659193 0.165 ENST00000330862.3
TMEM89
transmembrane protein 89
chr6_-_152793728 0.164 ENST00000495090.2
SYNE1
spectrin repeat containing, nuclear envelope 1
chr13_+_111837279 0.162 ENST00000467053.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr12_-_25348007 0.162 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr15_+_58724184 0.162 ENST00000433326.2
LIPC
lipase, hepatic
chr12_+_26348429 0.161 ENST00000242729.2
SSPN
sarcospan
chrX_-_71458802 0.160 ENST00000373657.1
ENST00000334463.3
ERCC6L

excision repair cross-complementing rodent repair deficiency, complementation group 6-like

chr3_+_135969148 0.156 ENST00000251654.4
ENST00000490504.1
ENST00000483687.1
ENST00000468777.1
ENST00000462637.1
ENST00000466072.1
ENST00000482086.1
ENST00000471595.1
ENST00000469217.1
ENST00000465423.1
ENST00000478469.1
PCCB










propionyl CoA carboxylase, beta polypeptide










chr4_-_138453606 0.155 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr19_+_45417921 0.154 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1


apolipoprotein C-I


chr3_-_156272872 0.153 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr15_+_62853562 0.153 ENST00000561311.1
TLN2
talin 2
chr6_+_155334780 0.152 ENST00000538270.1
ENST00000535231.1
TIAM2

T-cell lymphoma invasion and metastasis 2

chr11_-_102668879 0.151 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr5_+_53686658 0.148 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr19_+_23945768 0.147 ENST00000486528.1
ENST00000496398.1
RPSAP58

ribosomal protein SA pseudogene 58

chr3_+_156799587 0.146 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr13_+_111748183 0.145 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr5_+_151338426 0.144 ENST00000524034.1
CTB-12O2.1
CTB-12O2.1
chr9_-_4666421 0.144 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr12_+_26348246 0.143 ENST00000422622.2
SSPN
sarcospan
chr18_-_61311485 0.142 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4


serpin peptidase inhibitor, clade B (ovalbumin), member 4


chr2_-_89568263 0.142 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr5_-_136649218 0.140 ENST00000510405.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr22_+_23487513 0.139 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr3_-_99594948 0.139 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr15_-_36544450 0.137 ENST00000561394.1
RP11-184D12.1
RP11-184D12.1
chr9_-_107754034 0.137 ENST00000457720.1
RP11-217B7.3
RP11-217B7.3
chr14_+_95027772 0.137 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4

SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr3_-_156272924 0.135 ENST00000467789.1
ENST00000265044.2
SSR3

signal sequence receptor, gamma (translocon-associated protein gamma)

chr9_+_117904097 0.135 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr15_-_72668185 0.134 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr1_-_242612726 0.133 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr3_+_151531859 0.133 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr2_-_134326009 0.132 ENST00000409261.1
ENST00000409213.1
NCKAP5

NCK-associated protein 5

chr4_+_76481258 0.132 ENST00000311623.4
ENST00000435974.2
C4orf26

chromosome 4 open reading frame 26

chrX_-_138724677 0.132 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2


MCF.2 cell line derived transforming sequence


chr1_-_39339777 0.132 ENST00000397572.2
MYCBP
MYC binding protein
chr16_-_66864806 0.132 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1






NEDD8 activating enzyme E1 subunit 1






chr2_-_17981462 0.131 ENST00000402989.1
ENST00000428868.1
SMC6

structural maintenance of chromosomes 6

chr17_+_6918354 0.131 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr21_-_23058648 0.129 ENST00000416182.1
AF241725.6
AF241725.6
chr17_+_34058639 0.129 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr15_+_64680003 0.129 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr14_+_94577074 0.128 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27








interferon, alpha-inducible protein 27








chr2_+_216410921 0.128 ENST00000417485.2
AC012668.2
AC012668.2
chr7_+_107224364 0.127 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr3_-_99595037 0.127 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr13_-_30160925 0.127 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr10_-_50396407 0.127 ENST00000374153.2
ENST00000374151.3
C10orf128

chromosome 10 open reading frame 128

chr10_-_99030395 0.126 ENST00000355366.5
ENST00000371027.1
ARHGAP19

Rho GTPase activating protein 19

chrX_-_154689596 0.126 ENST00000369444.2
H2AFB3
H2A histone family, member B3
chr10_-_99052382 0.126 ENST00000466484.1
ENST00000358531.4
ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ARHGAP19

ARHGAP19-SLIT1


Rho GTPase activating protein 19

ARHGAP19-SLIT1 readthrough (NMD candidate)


chr11_+_7618413 0.125 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_70080449 0.125 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr11_+_60739249 0.125 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6



CD6 molecule



chr15_-_72523924 0.124 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM



pyruvate kinase, muscle



chr1_+_12851545 0.124 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr8_+_7738726 0.124 ENST00000314357.3
DEFB103A
defensin, beta 103A
chr3_-_12587055 0.124 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr11_-_321050 0.124 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr11_+_6942205 0.123 ENST00000317834.3
OR2D3
olfactory receptor, family 2, subfamily D, member 3
chr1_-_205391178 0.123 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr4_-_88450372 0.123 ENST00000543631.1
SPARCL1
SPARC-like 1 (hevin)
chr14_-_52436247 0.122 ENST00000597846.1
AL358333.1
HCG2013195; Uncharacterized protein
chr12_+_94071341 0.122 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr2_+_86333340 0.121 ENST00000409783.2
ENST00000409277.3
PTCD3

pentatricopeptide repeat domain 3

chr5_+_42756903 0.121 ENST00000361970.5
ENST00000388827.4
CCDC152

coiled-coil domain containing 152

chr14_-_67878917 0.119 ENST00000216446.4
PLEK2
pleckstrin 2
chr10_-_134756030 0.119 ENST00000368586.5
ENST00000368582.2
TTC40

tetratricopeptide repeat domain 40

chr21_-_42219065 0.119 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr2_+_228736321 0.115 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr15_+_54901540 0.115 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.4 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.4 GO:1902523 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.4 GO:1904970 brush border assembly(GO:1904970)
0.1 1.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.7 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.0 GO:0045861 negative regulation of proteolysis(GO:0045861)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0031346 positive regulation of cell projection organization(GO:0031346)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0015822 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784) positive regulation of dopamine secretion(GO:0033603)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.0 0.0 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.0 GO:0046066 dGDP metabolic process(GO:0046066)
0.0 0.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.0 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.0 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.0 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0007368 determination of left/right symmetry(GO:0007368)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.1 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0042585 female germ cell nucleus(GO:0001674) germinal vesicle(GO:0042585)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.0 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.0 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.6 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.4 GO:0033265 choline binding(GO:0033265)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.2 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.0 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 1.0 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)