Motif ID: RFX3_RFX2
Z-value: 1.736
Transcription factors associated with RFX3_RFX2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| RFX2 | ENSG00000087903.8 | RFX2 |
| RFX3 | ENSG00000080298.11 | RFX3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RFX3 | hg19_v2_chr9_-_3525968_3526016 | -0.87 | 2.4e-03 | Click! |
| RFX2 | hg19_v2_chr19_-_6110474_6110551 | 0.72 | 2.8e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.7 | GO:1904448 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 0.4 | 3.8 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.4 | 1.3 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 0.3 | 1.0 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 0.3 | 3.2 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.3 | 0.9 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.3 | 1.2 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.3 | 0.8 | GO:0070512 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 0.3 | 0.8 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 0.2 | 1.5 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.2 | 1.8 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 0.2 | 1.1 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.2 | 0.7 | GO:0050758 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.2 | 0.9 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.2 | 1.7 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.2 | 1.0 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.2 | 0.9 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.2 | 6.1 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.2 | 0.6 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.2 | 2.1 | GO:0097688 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.2 | 0.8 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
| 0.1 | 0.4 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.1 | 1.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 0.4 | GO:0046495 | nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
| 0.1 | 0.4 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.1 | 0.2 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.1 | 0.8 | GO:1903751 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.1 | 0.8 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.1 | 0.5 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.1 | 2.5 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 1.5 | GO:0018210 | peptidyl-threonine modification(GO:0018210) |
| 0.1 | 0.4 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.1 | 0.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.1 | 0.9 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.1 | 0.4 | GO:0031392 | regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) |
| 0.1 | 0.4 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 0.6 | GO:1904637 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 0.1 | 0.6 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.7 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.1 | 0.2 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.1 | 1.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.6 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.1 | 0.4 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.1 | 0.2 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 0.1 | 0.9 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 0.1 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.1 | 0.9 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.2 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.1 | 0.2 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 0.1 | 0.2 | GO:0006174 | dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.4 | GO:0010752 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.1 | 0.4 | GO:0070164 | ectopic germ cell programmed cell death(GO:0035234) negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.3 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.1 | 0.5 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.0 | 0.3 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.0 | 0.6 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
| 0.0 | 0.2 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 0.0 | 0.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.0 | 0.1 | GO:0044782 | cilium organization(GO:0044782) |
| 0.0 | 0.1 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 0.0 | 3.2 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.0 | 0.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.0 | 1.7 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.4 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 0.6 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.0 | 1.1 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 1.9 | GO:0042417 | dopamine metabolic process(GO:0042417) |
| 0.0 | 0.1 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.0 | 0.2 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.0 | 0.4 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.2 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 0.0 | 0.1 | GO:0070376 | regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377) |
| 0.0 | 0.3 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.0 | 0.6 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.0 | 1.3 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 1.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.1 | GO:0042245 | RNA repair(GO:0042245) |
| 0.0 | 0.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.0 | 0.2 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.0 | 0.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.0 | 0.2 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 0.0 | 3.7 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.4 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.0 | 0.4 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.0 | 0.3 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.0 | 0.2 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 0.1 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
| 0.0 | 0.1 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.0 | 0.5 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.0 | 0.1 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.0 | 0.1 | GO:0051086 | chaperone mediated protein folding independent of cofactor(GO:0051086) |
| 0.0 | 0.6 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.0 | 0.5 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.0 | 0.1 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.0 | 0.2 | GO:0003356 | regulation of cilium beat frequency(GO:0003356) |
| 0.0 | 0.1 | GO:0035549 | positive regulation of interferon-beta secretion(GO:0035549) |
| 0.0 | 0.2 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.0 | 1.8 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 0.1 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.0 | 0.2 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.0 | 0.1 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 0.2 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.0 | 0.5 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.2 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.0 | 0.2 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.0 | 0.0 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.1 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.0 | 1.0 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.0 | 1.6 | GO:0016574 | histone ubiquitination(GO:0016574) |
| 0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 1.0 | GO:0006363 | transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.2 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 0.2 | GO:2000483 | negative regulation of defense response to bacterium(GO:1900425) negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.0 | 0.4 | GO:0046321 | positive regulation of fatty acid oxidation(GO:0046321) |
| 0.0 | 0.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.2 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.0 | 0.2 | GO:2000544 | cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544) |
| 0.0 | 0.2 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.0 | 0.6 | GO:0035357 | peroxisome proliferator activated receptor signaling pathway(GO:0035357) |
| 0.0 | 0.1 | GO:0039007 | regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862) pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121) |
| 0.0 | 0.1 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 0.2 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 0.2 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.0 | 0.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 0.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 0.8 | GO:0007405 | neuroblast proliferation(GO:0007405) |
| 0.0 | 0.5 | GO:0008356 | asymmetric cell division(GO:0008356) |
| 0.0 | 0.1 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.0 | 0.3 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 0.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.1 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.0 | 0.2 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.2 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 0.1 | GO:0045007 | depurination(GO:0045007) |
| 0.0 | 0.3 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.0 | 0.1 | GO:0005980 | glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.0 | 0.1 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.0 | 2.3 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.0 | 0.1 | GO:1903912 | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912) |
| 0.0 | 0.2 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.0 | 0.1 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.0 | 1.6 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.2 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 0.1 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.1 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.0 | 1.1 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.3 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.5 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.0 | 0.3 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.0 | 0.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 1.0 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.3 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.0 | 0.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.1 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.6 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 1.1 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.5 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.4 | GO:0001975 | response to amphetamine(GO:0001975) |
| 0.0 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.0 | 1.2 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) |
| 0.0 | 0.5 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.7 | GO:0030148 | sphingolipid biosynthetic process(GO:0030148) |
| 0.0 | 0.3 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.3 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 0.5 | GO:0045687 | positive regulation of glial cell differentiation(GO:0045687) |
| 0.0 | 0.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.1 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.0 | 0.2 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
| 0.0 | 0.7 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.3 | GO:0097224 | sperm connecting piece(GO:0097224) |
| 0.5 | 2.7 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.2 | 2.7 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.2 | 0.8 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 0.2 | 1.2 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.2 | 2.1 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.2 | 1.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.1 | 3.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 0.7 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.1 | 0.4 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.1 | 1.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 0.8 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 1.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 1.3 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.1 | 1.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 1.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 0.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 0.7 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.1 | 0.9 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 0.4 | GO:0034448 | EGO complex(GO:0034448) |
| 0.1 | 0.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 1.0 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 1.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.0 | 1.0 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 1.7 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 3.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.2 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.5 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 0.2 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.0 | 0.9 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.2 | GO:0036156 | inner dynein arm(GO:0036156) |
| 0.0 | 0.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.0 | 0.6 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.6 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.3 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 0.4 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.5 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.5 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.2 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.0 | 0.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 1.1 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 1.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.8 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 0.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.1 | GO:1990031 | pinceau fiber(GO:1990031) |
| 0.0 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.9 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 0.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.0 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 0.2 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.0 | 1.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.4 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.4 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.2 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.2 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.0 | 0.4 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 1.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.2 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.5 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.3 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.1 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 0.3 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
| 0.0 | 0.1 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 1.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.1 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.0 | GO:0097451 | astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451) |
| 0.0 | 0.3 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 1.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.1 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 1.4 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.9 | GO:0043195 | terminal bouton(GO:0043195) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.7 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.5 | 2.1 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.3 | 0.9 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.3 | 0.8 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 0.2 | 3.3 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.2 | 2.5 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 0.5 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.2 | 0.5 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.1 | 3.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.4 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.1 | 0.7 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.1 | 0.6 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 0.2 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.1 | 1.0 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.1 | 0.4 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.1 | 2.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 1.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.1 | 0.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 0.1 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 0.3 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.1 | 0.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 0.9 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.1 | 0.5 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.1 | 2.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.4 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 0.3 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.1 | 1.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.3 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 0.0 | 1.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.7 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.1 | GO:0033677 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142) |
| 0.0 | 1.2 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 1.3 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.4 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.0 | 1.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.5 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.6 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.6 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 0.2 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.0 | 0.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 1.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.1 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.0 | 0.7 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.1 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.0 | 0.2 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.2 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.0 | 2.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.2 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.0 | 0.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.6 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.0 | 0.6 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.6 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 1.2 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 0.2 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.8 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 0.2 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.0 | 0.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.1 | GO:0033823 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211) |
| 0.0 | 0.3 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.0 | 0.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.4 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.0 | 0.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.1 | GO:0052836 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.0 | 0.8 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.1 | GO:0035473 | lipase binding(GO:0035473) |
| 0.0 | 0.4 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.9 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.2 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 1.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 1.0 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.0 | 0.2 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.0 | 0.2 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.0 | 0.1 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.0 | 0.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.0 | 0.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 0.1 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.0 | 0.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.4 | GO:0099604 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
| 0.0 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.1 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.0 | 0.8 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.1 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.0 | 3.0 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 1.3 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.1 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.0 | 0.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 1.1 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 1.1 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.1 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.2 | GO:0004532 | exoribonuclease activity(GO:0004532) |
| 0.0 | 0.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 1.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.6 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.1 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.5 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 2.3 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 3.3 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.0 | 2.7 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 2.3 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.7 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.5 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.0 | 0.4 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 1.2 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 1.0 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.4 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.4 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 2.6 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 0.9 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.1 | 2.7 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 1.0 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.5 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.7 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 1.2 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 1.2 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 1.4 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 0.6 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 1.5 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.3 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.0 | 1.3 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.8 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.5 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.2 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.0 | 0.5 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.0 | 1.1 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.6 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.6 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 2.6 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.3 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.3 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.5 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.4 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 1.6 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.9 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.4 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 0.3 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.2 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 1.9 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.5 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.2 | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.0 | 0.3 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.2 | REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |


