Motif ID: RELA

Z-value: 0.491


Transcription factors associated with RELA:

Gene SymbolEntrez IDGene Name
RELA ENSG00000173039.14 RELA

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430554_654305790.618.2e-02Click!


Activity profile for motif RELA.

activity profile for motif RELA


Sorted Z-values histogram for motif RELA

Sorted Z-values for motif RELA



Network of associatons between targets according to the STRING database.



First level regulatory network of RELA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792295 1.227 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr11_+_34642656 0.857 ENST00000257831.3
ENST00000450654.2
EHF

ets homologous factor

chr1_+_110453514 0.449 ENST00000369802.3
ENST00000420111.2
CSF1

colony stimulating factor 1 (macrophage)

chr1_+_110453462 0.425 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr1_+_110453203 0.419 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr11_+_102188272 0.419 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr5_+_159895275 0.417 ENST00000517927.1
MIR146A
microRNA 146a
chr1_+_110453109 0.410 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_102188224 0.376 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr7_-_16844611 0.363 ENST00000401412.1
ENST00000419304.2
AGR2

anterior gradient 2

chr4_-_76957214 0.340 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr7_+_22766766 0.297 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr1_+_201979645 0.270 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr1_+_201979743 0.252 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_-_76944621 0.248 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chrX_-_73072534 0.247 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr4_-_74964904 0.235 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr1_-_39395165 0.231 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr1_+_6845384 0.230 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr17_+_16318909 0.223 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_-_204436344 0.221 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr1_+_182584314 0.215 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr1_-_41950342 0.208 ENST00000372587.4
EDN2
endothelin 2
chr17_+_16318850 0.206 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr11_-_7961141 0.205 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr1_+_6845578 0.198 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr7_-_126892303 0.195 ENST00000358373.3
GRM8
glutamate receptor, metabotropic 8
chr1_+_6845497 0.189 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr5_-_141257954 0.186 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr1_+_56880606 0.186 ENST00000451914.1
RP4-710M16.2
RP4-710M16.2
chr19_+_496454 0.181 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1


mucosal vascular addressin cell adhesion molecule 1


chr4_-_40631859 0.178 ENST00000295971.7
ENST00000319592.4
RBM47

RNA binding motif protein 47

chr10_+_12391685 0.178 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr15_+_26360970 0.175 ENST00000556159.1
ENST00000557523.1
LINC00929

long intergenic non-protein coding RNA 929

chr12_+_7055631 0.172 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr11_-_58345569 0.170 ENST00000528954.1
ENST00000528489.1
LPXN

leupaxin

chr10_+_12391481 0.163 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr6_-_33160231 0.157 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chr10_+_52833883 0.148 ENST00000373980.4
PRKG1
protein kinase, cGMP-dependent, type I
chr6_+_33378517 0.147 ENST00000428274.1
PHF1
PHD finger protein 1
chr8_+_42128861 0.144 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr1_+_46640750 0.140 ENST00000372003.1
TSPAN1
tetraspanin 1
chr3_+_184032919 0.139 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr10_+_75668916 0.138 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr17_+_63133587 0.138 ENST00000449996.3
ENST00000262406.9
RGS9

regulator of G-protein signaling 9

chr2_-_163175133 0.132 ENST00000421365.2
ENST00000263642.2
IFIH1

interferon induced with helicase C domain 1

chr1_+_169077133 0.128 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_169077172 0.126 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr11_-_790060 0.124 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr3_+_184033135 0.123 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr9_-_140115775 0.123 ENST00000391553.1
ENST00000392827.1
RNF208

ring finger protein 208

chr5_-_35230434 0.121 ENST00000504500.1
PRLR
prolactin receptor
chr11_+_65190245 0.115 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1


nuclear paraspeckle assembly transcript 1 (non-protein coding)


chr3_+_184033551 0.114 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr6_-_30712313 0.112 ENST00000376377.2
ENST00000259874.5
IER3

immediate early response 3

chr6_+_31540056 0.111 ENST00000418386.2
LTA
lymphotoxin alpha
chr19_+_3721719 0.110 ENST00000589378.1
ENST00000382008.3
TJP3

tight junction protein 3

chr22_-_19512893 0.109 ENST00000403084.1
ENST00000413119.2
CLDN5

claudin 5

chr18_+_32290218 0.105 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr17_+_63133526 0.104 ENST00000443584.3
RGS9
regulator of G-protein signaling 9
chr1_+_15853308 0.104 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DNAJC16


DnaJ (Hsp40) homolog, subfamily C, member 16


chr1_-_236030216 0.102 ENST00000389794.3
ENST00000389793.2
LYST

lysosomal trafficking regulator

chr1_-_186649543 0.102 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr14_-_35873856 0.098 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha


chr8_-_10987745 0.097 ENST00000400102.3
AF131215.5
AF131215.5
chr12_-_24103954 0.095 ENST00000441133.2
ENST00000545921.1
SOX5

SRY (sex determining region Y)-box 5

chr9_+_35806082 0.095 ENST00000447210.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr4_+_4861385 0.094 ENST00000382723.4
MSX1
msh homeobox 1
chr6_+_33378738 0.092 ENST00000374512.3
ENST00000374516.3
PHF1

PHD finger protein 1

chr2_+_112895939 0.092 ENST00000331203.2
ENST00000409903.1
ENST00000409667.3
ENST00000409450.3
FBLN7



fibulin 7



chr8_-_70747205 0.091 ENST00000260126.4
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr4_+_41614720 0.090 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr8_+_38758737 0.087 ENST00000521746.1
ENST00000420274.1
PLEKHA2

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2

chr8_+_42128812 0.087 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
IKBKB




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta




chr9_+_19230433 0.086 ENST00000434457.2
ENST00000602925.1
DENND4C

DENN/MADD domain containing 4C

chr4_+_41614909 0.085 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr6_-_32122106 0.084 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr5_-_141338377 0.083 ENST00000510041.1
PCDH12
protocadherin 12
chr5_+_150591678 0.081 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr9_+_127615733 0.080 ENST00000373574.1
WDR38
WD repeat domain 38
chr2_+_228678550 0.080 ENST00000409189.3
ENST00000358813.4
CCL20

chemokine (C-C motif) ligand 20

chr10_+_30722866 0.080 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr6_-_32636145 0.080 ENST00000399084.1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr1_+_54359854 0.079 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1





deiodinase, iodothyronine, type I





chr1_-_23694794 0.077 ENST00000374608.3
ZNF436
zinc finger protein 436
chr8_-_11058847 0.077 ENST00000297303.4
ENST00000416569.2
XKR6

XK, Kell blood group complex subunit-related family, member 6

chr2_+_17721920 0.075 ENST00000295156.4
VSNL1
visinin-like 1
chr2_+_17721937 0.075 ENST00000451533.1
VSNL1
visinin-like 1
chr8_+_38758845 0.073 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr13_-_38443860 0.073 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr5_-_55290773 0.072 ENST00000502326.3
ENST00000381298.2
IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

chr15_+_76352178 0.072 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr19_-_39390212 0.071 ENST00000437828.1
SIRT2
sirtuin 2
chr8_+_9413410 0.071 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS


tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase


chr13_+_108922228 0.069 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr17_+_38474489 0.067 ENST00000394089.2
ENST00000425707.3
RARA

retinoic acid receptor, alpha

chr19_-_39390440 0.067 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2


sirtuin 2


chr1_+_8021954 0.066 ENST00000377491.1
ENST00000377488.1
PARK7

parkinson protein 7

chr17_+_25799008 0.066 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1


kinase suppressor of ras 1


chr1_-_36615051 0.066 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr7_-_93520191 0.066 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr16_+_50775948 0.066 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD


cylindromatosis (turban tumor syndrome)


chr16_+_50775971 0.066 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD


cylindromatosis (turban tumor syndrome)


chr1_-_36615065 0.066 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3


trafficking protein particle complex 3


chr5_-_150460914 0.065 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr18_+_3450161 0.064 ENST00000551402.1
ENST00000577543.1
TGIF1

TGFB-induced factor homeobox 1

chr19_-_9879293 0.064 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846


zinc finger protein 846


chr2_-_231789941 0.064 ENST00000392040.1
ENST00000438398.1
GPR55

G protein-coupled receptor 55

chr1_+_159796589 0.064 ENST00000368104.4
SLAMF8
SLAM family member 8
chr6_+_32121908 0.064 ENST00000375143.2
ENST00000424499.1
PPT2

palmitoyl-protein thioesterase 2

chr17_+_21191341 0.063 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3


mitogen-activated protein kinase kinase 3


chr19_+_42381337 0.063 ENST00000597454.1
ENST00000444740.2
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr19_+_10381769 0.062 ENST00000423829.2
ENST00000588645.1
ICAM1

intercellular adhesion molecule 1

chr16_+_50776021 0.061 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD


cylindromatosis (turban tumor syndrome)


chr9_-_130693048 0.061 ENST00000388747.4
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr12_-_76425368 0.061 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr5_-_127418573 0.060 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3



CTC-228N24.3



chr7_-_93520259 0.059 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chrX_-_48827976 0.059 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_-_39390350 0.059 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2


sirtuin 2


chr17_+_46133307 0.058 ENST00000580037.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr11_+_66059339 0.058 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr2_-_109605663 0.057 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr5_-_127418755 0.057 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3




CTC-228N24.3




chr6_+_32121789 0.056 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr7_+_143078652 0.055 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr2_-_206950781 0.055 ENST00000403263.1
INO80D
INO80 complex subunit D
chr4_-_187644930 0.054 ENST00000441802.2
FAT1
FAT atypical cadherin 1
chr9_-_125667494 0.052 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2


ring finger and CCCH-type domains 2


chr3_-_168864315 0.051 ENST00000475754.1
ENST00000484519.1
MECOM

MDS1 and EVI1 complex locus

chr12_-_57504069 0.051 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6


signal transducer and activator of transcription 6, interleukin-4 induced


chrX_-_48901012 0.051 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr17_-_75878647 0.050 ENST00000374983.2
FLJ45079
FLJ45079
chr14_+_24616588 0.050 ENST00000324103.6
ENST00000559260.1
RNF31

ring finger protein 31

chr11_+_73000449 0.049 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr9_+_127054254 0.048 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr7_+_143078379 0.048 ENST00000449630.1
ENST00000457235.1
ZYX

zyxin

chr16_-_66959429 0.048 ENST00000420652.1
ENST00000299759.6
RRAD

Ras-related associated with diabetes

chr11_-_96076334 0.047 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr10_-_100174900 0.047 ENST00000370575.4
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr2_-_211036051 0.046 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chr4_-_103749205 0.046 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_-_22487588 0.046 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr16_+_28834531 0.045 ENST00000570200.1
ATXN2L
ataxin 2-like
chr17_+_34900737 0.045 ENST00000304718.4
ENST00000485685.2
GGNBP2

gametogenetin binding protein 2

chr14_+_61789382 0.045 ENST00000555082.1
PRKCH
protein kinase C, eta
chr6_-_24720226 0.045 ENST00000378102.3
C6orf62
chromosome 6 open reading frame 62
chr13_+_108921977 0.045 ENST00000430559.1
ENST00000375887.4
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr5_+_177019159 0.044 ENST00000332598.6
TMED9
transmembrane emp24 protein transport domain containing 9
chr7_-_56101826 0.044 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr9_+_127054217 0.043 ENST00000394199.2
ENST00000546191.1
NEK6

NIMA-related kinase 6

chr3_-_194072019 0.043 ENST00000429275.1
ENST00000323830.3
CPN2

carboxypeptidase N, polypeptide 2

chr2_-_61108449 0.043 ENST00000439412.1
ENST00000452343.1
AC010733.4

AC010733.4

chr4_+_146560245 0.043 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr3_-_4793274 0.043 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr12_-_24103841 0.043 ENST00000541847.1
SOX5
SRY (sex determining region Y)-box 5
chr1_-_205744205 0.042 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr19_+_41725140 0.042 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr9_-_125667618 0.042 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr3_+_159706537 0.041 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A


interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)


chr5_+_140535577 0.041 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr5_-_178054014 0.041 ENST00000520957.1
CLK4
CDC-like kinase 4
chrX_-_131352152 0.041 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr2_+_202047596 0.041 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr14_-_24616426 0.040 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr2_+_202047843 0.040 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10




caspase 10, apoptosis-related cysteine peptidase




chr19_+_41725088 0.040 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr11_+_46299199 0.039 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr14_+_75536335 0.038 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C



zinc finger, C2HC-type containing 1C



chr3_+_197518100 0.038 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3




leucine-rich repeats and calponin homology (CH) domain containing 3




chr6_+_144471643 0.037 ENST00000367568.4
STX11
syntaxin 11
chr2_-_43453734 0.037 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr5_+_118604439 0.037 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr10_+_30723105 0.037 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chrX_-_139015153 0.036 ENST00000370557.1
ATP11C
ATPase, class VI, type 11C
chr1_+_8021713 0.036 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
PARK7


parkinson protein 7


chr17_-_34207295 0.036 ENST00000463941.1
ENST00000293272.3
CCL5

chemokine (C-C motif) ligand 5

chr19_+_40873617 0.035 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr4_-_103749179 0.035 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr18_+_3252265 0.035 ENST00000580887.1
ENST00000536605.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr14_+_75536280 0.035 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr2_+_166428839 0.034 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_-_103749105 0.034 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr5_+_133984462 0.033 ENST00000398844.2
ENST00000322887.4
SEC24A

SEC24 family member A

chr6_-_30080876 0.033 ENST00000376734.3
TRIM31
tripartite motif containing 31
chrX_+_48755183 0.033 ENST00000376563.1
ENST00000376566.4
PQBP1

polyglutamine binding protein 1

chr16_+_28835437 0.033 ENST00000568266.1
ATXN2L
ataxin 2-like
chr4_-_103748880 0.033 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr2_-_240230890 0.032 ENST00000446876.1
HDAC4
histone deacetylase 4
chr8_+_55466915 0.032 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr5_-_142077569 0.032 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1


fibroblast growth factor 1 (acidic)


chr2_+_208394616 0.032 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr6_+_30297306 0.032 ENST00000420746.1
ENST00000513556.1
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr15_-_51914810 0.031 ENST00000543779.2
ENST00000449909.3
DMXL2

Dmx-like 2

chr5_-_150467221 0.031 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr4_-_122085469 0.031 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr2_+_208394455 0.030 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr5_+_118604385 0.030 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_-_150460539 0.030 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1



TNFAIP3 interacting protein 1



chr3_-_158390282 0.030 ENST00000264265.3
LXN
latexin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.2 1.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.3 GO:0001878 response to yeast(GO:0001878)
0.1 0.2 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.1 GO:0002925 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.4 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.3 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.8 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.1 GO:0050787 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0034182 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:1990619 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 1.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0008144 drug binding(GO:0008144)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 ST_STAT3_PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)