Motif ID: REL

Z-value: 0.284


Transcription factors associated with REL:

Gene SymbolEntrez IDGene Name
REL ENSG00000162924.9 REL

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108650_611086870.599.3e-02Click!


Activity profile for motif REL.

activity profile for motif REL


Sorted Z-values histogram for motif REL

Sorted Z-values for motif REL



Network of associatons between targets according to the STRING database.



First level regulatory network of REL

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149792295 0.402 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr7_-_16844611 0.244 ENST00000401412.1
ENST00000419304.2
AGR2

anterior gradient 2

chr1_+_207262170 0.235 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr4_-_76957214 0.202 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr1_+_110453514 0.191 ENST00000369802.3
ENST00000420111.2
CSF1

colony stimulating factor 1 (macrophage)

chr1_+_110453203 0.182 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr1_+_110453462 0.180 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_102188272 0.173 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr8_+_55466915 0.171 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr1_+_110453109 0.170 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_102188224 0.153 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr12_-_86230315 0.146 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr20_+_43803517 0.140 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr10_-_46970533 0.133 ENST00000512997.1
SYT15
synaptotagmin XV
chr19_+_496454 0.131 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1


mucosal vascular addressin cell adhesion molecule 1


chr9_+_130911723 0.128 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr2_-_204400113 0.126 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_-_204436344 0.121 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr9_+_130911770 0.119 ENST00000372998.1
LCN2
lipocalin 2
chr18_+_21529811 0.118 ENST00000588004.1
LAMA3
laminin, alpha 3
chr5_-_115890554 0.116 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_-_58345569 0.114 ENST00000528954.1
ENST00000528489.1
LPXN

leupaxin

chr18_+_21452964 0.106 ENST00000587184.1
LAMA3
laminin, alpha 3
chr1_+_6845384 0.103 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr12_+_7055631 0.102 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr1_+_6845578 0.102 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr12_-_49318715 0.099 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr1_+_201979743 0.097 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr15_-_73661605 0.095 ENST00000261917.3
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr1_+_56880606 0.093 ENST00000451914.1
RP4-710M16.2
RP4-710M16.2
chr3_+_183967409 0.093 ENST00000324557.4
ENST00000402825.3
ECE2

endothelin converting enzyme 2

chr18_+_21452804 0.092 ENST00000269217.6
LAMA3
laminin, alpha 3
chr3_-_179322436 0.091 ENST00000392659.2
ENST00000476781.1
MRPL47

mitochondrial ribosomal protein L47

chr7_-_126892303 0.091 ENST00000358373.3
GRM8
glutamate receptor, metabotropic 8
chr5_-_141703713 0.090 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr3_-_179322416 0.090 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr3_+_179322573 0.084 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa


chr11_-_7961141 0.083 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr3_+_179322481 0.082 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr3_-_183967296 0.082 ENST00000455059.1
ENST00000445626.2
ALG3

ALG3, alpha-1,3- mannosyltransferase

chr1_+_6845497 0.079 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr21_+_46875424 0.079 ENST00000359759.4
COL18A1
collagen, type XVIII, alpha 1
chr11_+_65190245 0.078 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1


nuclear paraspeckle assembly transcript 1 (non-protein coding)


chr2_-_163175133 0.077 ENST00000421365.2
ENST00000263642.2
IFIH1

interferon induced with helicase C domain 1

chr22_+_22676808 0.076 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr3_+_89156674 0.073 ENST00000336596.2
EPHA3
EPH receptor A3
chr17_-_4642429 0.072 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr3_-_178790057 0.071 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr1_+_201979645 0.071 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr15_+_26360970 0.069 ENST00000556159.1
ENST00000557523.1
LINC00929

long intergenic non-protein coding RNA 929

chr3_-_178789993 0.069 ENST00000432729.1
ZMAT3
zinc finger, matrin-type 3
chr13_+_95364963 0.067 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr22_-_19512893 0.067 ENST00000403084.1
ENST00000413119.2
CLDN5

claudin 5

chr17_-_4643161 0.065 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr3_-_178789220 0.064 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr19_-_57967854 0.062 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr8_+_42128861 0.061 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr12_-_77272765 0.060 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2



cysteine and glycine-rich protein 2



chr19_-_9879293 0.057 ENST00000397902.2
ENST00000592859.1
ENST00000588267.1
ZNF846


zinc finger protein 846


chr5_-_35230434 0.056 ENST00000504500.1
PRLR
prolactin receptor
chr2_+_204192942 0.055 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr15_+_42131011 0.053 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr8_+_55467072 0.052 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr12_-_53297432 0.052 ENST00000546900.1
KRT8
keratin 8
chr10_+_90750493 0.051 ENST00000357339.2
ENST00000355279.2
FAS

Fas cell surface death receptor

chr13_-_38443860 0.051 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr6_-_46048116 0.051 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr6_-_31774714 0.051 ENST00000375661.5
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_32122106 0.050 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr2_-_128145498 0.050 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr3_+_89156799 0.048 ENST00000452448.2
ENST00000494014.1
EPHA3

EPH receptor A3

chr1_-_8086343 0.048 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1


ERBB receptor feedback inhibitor 1


chr6_+_13925170 0.046 ENST00000471906.1
RNF182
ring finger protein 182
chr8_+_42128812 0.045 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
IKBKB




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta




chr10_+_90750378 0.045 ENST00000355740.2
ENST00000352159.4
FAS

Fas cell surface death receptor

chr1_+_95582881 0.042 ENST00000370203.4
ENST00000456991.1
TMEM56

transmembrane protein 56

chr1_-_9189144 0.042 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr3_+_184081137 0.042 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr8_-_119964434 0.040 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr19_+_3721719 0.040 ENST00000589378.1
ENST00000382008.3
TJP3

tight junction protein 3

chr9_+_101705893 0.040 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr5_+_150591678 0.040 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr19_-_39390212 0.039 ENST00000437828.1
SIRT2
sirtuin 2
chr10_+_30722866 0.039 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_-_91295304 0.038 ENST00000341233.4
ENST00000371790.4
SLC16A12

solute carrier family 16, member 12

chr17_+_25799008 0.038 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1


kinase suppressor of ras 1


chr2_+_204193149 0.038 ENST00000422511.2
ABI2
abl-interactor 2
chr22_+_46546494 0.037 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
PPARA


peroxisome proliferator-activated receptor alpha


chr8_-_105601134 0.036 ENST00000276654.5
ENST00000424843.2
LRP12

low density lipoprotein receptor-related protein 12

chr12_+_53491220 0.036 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr4_+_72897521 0.036 ENST00000308744.6
ENST00000344413.5
NPFFR2

neuropeptide FF receptor 2

chr11_-_61734599 0.036 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr14_-_35183886 0.036 ENST00000298159.6
CFL2
cofilin 2 (muscle)
chr6_+_32121908 0.036 ENST00000375143.2
ENST00000424499.1
PPT2

palmitoyl-protein thioesterase 2

chr2_+_228678550 0.035 ENST00000409189.3
ENST00000358813.4
CCL20

chemokine (C-C motif) ligand 20

chr17_+_38474489 0.035 ENST00000394089.2
ENST00000425707.3
RARA

retinoic acid receptor, alpha

chr2_+_204193129 0.035 ENST00000417864.1
ABI2
abl-interactor 2
chr12_-_76425368 0.035 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chrX_+_48755183 0.035 ENST00000376563.1
ENST00000376566.4
PQBP1

polyglutamine binding protein 1

chr19_-_39390440 0.034 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2


sirtuin 2


chr17_+_2264983 0.033 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr17_-_75878647 0.033 ENST00000374983.2
FLJ45079
FLJ45079
chr12_+_50690489 0.033 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr2_+_202047596 0.033 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr2_+_202047843 0.032 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10




caspase 10, apoptosis-related cysteine peptidase




chr6_+_32121789 0.032 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr2_+_204193101 0.032 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2


abl-interactor 2


chr14_+_24616588 0.032 ENST00000324103.6
ENST00000559260.1
RNF31

ring finger protein 31

chr19_-_39390350 0.031 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2


sirtuin 2


chr2_-_43453734 0.031 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr10_-_100027943 0.031 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr1_-_6453426 0.030 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr15_-_51914996 0.029 ENST00000251076.5
DMXL2
Dmx-like 2
chr6_-_44233361 0.028 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr1_+_16767195 0.028 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2



NECAP endocytosis associated 2



chr1_-_23694794 0.028 ENST00000374608.3
ZNF436
zinc finger protein 436
chr5_-_55290773 0.028 ENST00000502326.3
ENST00000381298.2
IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

chr19_-_14064114 0.028 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr2_-_61108449 0.027 ENST00000439412.1
ENST00000452343.1
AC010733.4

AC010733.4

chr5_+_118604439 0.027 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr11_+_73000449 0.027 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr15_+_47476275 0.027 ENST00000558014.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr14_-_24616426 0.027 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr5_+_133984462 0.026 ENST00000398844.2
ENST00000322887.4
SEC24A

SEC24 family member A

chr18_+_3252265 0.026 ENST00000580887.1
ENST00000536605.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr5_-_150460914 0.026 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr6_-_30080863 0.026 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr5_+_118604385 0.025 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr6_-_30080876 0.024 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr11_-_64856497 0.024 ENST00000524632.1
ENST00000530719.1
AP003068.6

transmembrane protein 262

chr11_+_46316677 0.024 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr20_-_44485835 0.024 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8


acyl-CoA thioesterase 8


chr17_+_34639793 0.024 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2


chemokine (C-C motif) ligand 4-like 2


chr17_-_6338472 0.023 ENST00000570466.1
ENST00000576776.1
ENST00000576307.1
ENST00000381129.3
ENST00000250087.5
AIPL1




aryl hydrocarbon receptor interacting protein-like 1




chr1_-_93426998 0.023 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr4_-_56412713 0.023 ENST00000435527.2
CLOCK
clock circadian regulator
chr5_+_154136702 0.022 ENST00000524248.1
LARP1
La ribonucleoprotein domain family, member 1
chr6_+_15401075 0.022 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr1_-_27216729 0.022 ENST00000431781.2
ENST00000374135.4
GPN2

GPN-loop GTPase 2

chr9_-_132805430 0.022 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1


formin binding protein 1


chr5_-_127418573 0.022 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3



CTC-228N24.3



chr10_-_18948208 0.022 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr5_+_140535577 0.021 ENST00000539533.1
PCDHB17
Protocadherin-psi1; Uncharacterized protein
chr15_-_51914810 0.021 ENST00000543779.2
ENST00000449909.3
DMXL2

Dmx-like 2

chr5_+_112312416 0.021 ENST00000389063.2
DCP2
decapping mRNA 2
chr19_+_41725140 0.021 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr12_-_57504069 0.021 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6


signal transducer and activator of transcription 6, interleukin-4 induced


chr17_-_6338399 0.021 ENST00000570584.1
ENST00000574913.1
ENST00000571740.1
ENST00000575265.1
ENST00000574506.1
AIPL1




aryl hydrocarbon receptor interacting protein-like 1




chr19_+_41725088 0.020 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr8_-_123793048 0.020 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr18_+_33877654 0.020 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3



formin homology 2 domain containing 3



chr5_+_112312454 0.020 ENST00000543319.1
DCP2
decapping mRNA 2
chr5_-_127418755 0.020 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3




CTC-228N24.3




chr15_-_90892669 0.020 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr3_-_168864315 0.019 ENST00000475754.1
ENST00000484519.1
MECOM

MDS1 and EVI1 complex locus

chr2_-_191885686 0.019 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_+_208394616 0.019 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr5_-_150467221 0.018 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chrX_-_134186144 0.018 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chr3_+_169629354 0.018 ENST00000428432.2
ENST00000335556.3
SAMD7

sterile alpha motif domain containing 7

chr2_+_219264466 0.018 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr8_-_23712312 0.017 ENST00000290271.2
STC1
stanniocalcin 1
chr17_-_15469590 0.017 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr3_+_197518100 0.017 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3




leucine-rich repeats and calponin homology (CH) domain containing 3




chr2_-_177502659 0.017 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr16_+_31044812 0.017 ENST00000313843.3
STX4
syntaxin 4
chr4_+_169418195 0.017 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr17_-_4643114 0.017 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr4_-_103749205 0.017 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr15_+_76352178 0.016 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr2_-_220094031 0.016 ENST00000443140.1
ENST00000432520.1
ENST00000409618.1
ATG9A


autophagy related 9A


chr4_-_54930790 0.016 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr2_+_238600933 0.016 ENST00000420665.1
ENST00000392000.4
LRRFIP1

leucine rich repeat (in FLII) interacting protein 1

chr14_+_37667230 0.016 ENST00000556451.1
ENST00000556753.1
ENST00000396294.2
MIPOL1


mirror-image polydactyly 1


chr14_-_24658053 0.016 ENST00000354464.6
IPO4
importin 4
chr10_-_6104253 0.015 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA


interleukin 2 receptor, alpha


chr11_+_46299199 0.015 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr1_-_27816641 0.015 ENST00000430629.2
WASF2
WAS protein family, member 2
chr5_+_43602750 0.014 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr6_+_135502408 0.014 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr19_+_39390587 0.014 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB



nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta



chr4_+_26322185 0.014 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_208394794 0.014 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1


cAMP responsive element binding protein 1


chrX_-_48755030 0.014 ENST00000490755.2
ENST00000465150.2
ENST00000495490.2
TIMM17B


translocase of inner mitochondrial membrane 17 homolog B (yeast)


chr2_+_208394658 0.014 ENST00000421139.1
CREB1
cAMP responsive element binding protein 1
chr4_-_103749179 0.013 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr9_+_107456660 0.013 ENST00000318763.5
OR13D1
olfactory receptor, family 13, subfamily D, member 1
chr4_-_103749105 0.013 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr12_+_110718428 0.013 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr17_+_26662730 0.013 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_27816556 0.013 ENST00000536657.1
WASF2
WAS protein family, member 2
chr2_+_201987200 0.013 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_+_127054254 0.013 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr14_+_37667118 0.012 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
MIPOL1


mirror-image polydactyly 1


chr2_+_208394455 0.012 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr14_-_35873856 0.012 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha


chr9_+_127054217 0.012 ENST00000394199.2
ENST00000546191.1
NEK6

NIMA-related kinase 6

chr1_+_6615241 0.011 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1


taste receptor, type 1, member 1


chr21_+_34638656 0.011 ENST00000290200.2
IL10RB
interleukin 10 receptor, beta
chr3_+_141596371 0.011 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.4 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.0 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.0 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10