Motif ID: PROX1

Z-value: 0.316


Transcription factors associated with PROX1:

Gene SymbolEntrez IDGene Name
PROX1 ENSG00000117707.11 PROX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PROX1hg19_v2_chr1_+_214161272_2141613220.442.3e-01Click!


Activity profile for motif PROX1.

activity profile for motif PROX1


Sorted Z-values histogram for motif PROX1

Sorted Z-values for motif PROX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PROX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_52668394 0.331 ENST00000423955.2
 KRT86
keratin 86
chr1_+_82266053 0.220 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
 LPHN2






latrophilin 2






chr10_-_92681033 0.179 ENST00000371697.3
 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr8_-_19615382 0.172 ENST00000544602.1
 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr9_+_125133315 0.157 ENST00000223423.4
ENST00000362012.2
 PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr7_-_156433195 0.157 ENST00000333319.6
 C7orf13
chromosome 7 open reading frame 13
chr14_-_54425475 0.153 ENST00000559642.1
 BMP4
bone morphogenetic protein 4
chr1_-_159046617 0.142 ENST00000368130.4
 AIM2
absent in melanoma 2
chr8_-_19615538 0.139 ENST00000517494.1
 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_19615435 0.135 ENST00000523262.1
 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_33457453 0.130 ENST00000523956.1
ENST00000256261.4
 DUSP26

dual specificity phosphatase 26 (putative)

chr2_-_233877912 0.130 ENST00000264051.3
 NGEF
neuronal guanine nucleotide exchange factor
chr1_-_109203685 0.122 ENST00000402983.1
ENST00000420055.1
 HENMT1

HEN1 methyltransferase homolog 1 (Arabidopsis)

chr2_-_152830479 0.121 ENST00000360283.6
 CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_-_156569850 0.120 ENST00000524219.1
 HAVCR2
hepatitis A virus cellular receptor 2
chr20_-_749121 0.116 ENST00000217254.7
ENST00000381944.3
 SLC52A3

solute carrier family 52 (riboflavin transporter), member 3

chr2_+_128403720 0.116 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr1_+_154966058 0.115 ENST00000392487.1
 LENEP
lens epithelial protein
chr1_-_22222764 0.110 ENST00000439717.2
ENST00000412328.1
 HSPG2

heparan sulfate proteoglycan 2

chr2_+_128403439 0.106 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr1_-_44497024 0.102 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
 SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr19_-_5293243 0.099 ENST00000591760.1
 PTPRS
protein tyrosine phosphatase, receptor type, S
chr9_+_125132803 0.098 ENST00000540753.1
 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_44497118 0.092 ENST00000537678.1
ENST00000466926.1
 SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr18_-_21562500 0.084 ENST00000582300.2
 RP11-403A21.1
RP11-403A21.1
chr3_+_49941420 0.082 ENST00000419183.1
 CTD-2330K9.3
Uncharacterized protein
chr1_+_179335101 0.080 ENST00000508285.1
ENST00000511889.1
 AXDND1

axonemal dynein light chain domain containing 1

chr2_-_163175133 0.077 ENST00000421365.2
ENST00000263642.2
 IFIH1

interferon induced with helicase C domain 1

chr18_+_32073253 0.075 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA


dystrobrevin, alpha


chr12_-_122658746 0.073 ENST00000377035.1
 IL31
interleukin 31
chr1_+_10459111 0.073 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
 PGD



phosphogluconate dehydrogenase



chr2_+_28718921 0.073 ENST00000327757.5
ENST00000422425.2
ENST00000404858.1
 PLB1


phospholipase B1


chr1_-_109203648 0.073 ENST00000370031.1
 HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_+_70876891 0.073 ENST00000411986.2
 CTH
cystathionase (cystathionine gamma-lyase)
chr9_+_125133467 0.073 ENST00000426608.1
 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_32634425 0.072 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
 HLA-DQB1



major histocompatibility complex, class II, DQ beta 1



chr1_+_70876926 0.071 ENST00000370938.3
ENST00000346806.2
 CTH

cystathionase (cystathionine gamma-lyase)

chr5_+_6766004 0.067 ENST00000506093.1
 RP11-332J15.3
RP11-332J15.3
chr2_+_28618532 0.064 ENST00000545753.1
 FOSL2
FOS-like antigen 2
chr12_-_52946923 0.063 ENST00000267119.5
 KRT71
keratin 71
chr22_-_29075853 0.062 ENST00000397906.2
 TTC28
tetratricopeptide repeat domain 28
chr10_-_14920599 0.062 ENST00000609399.1
 RP11-398C13.6
RP11-398C13.6
chr6_-_31628512 0.061 ENST00000375911.1
 C6orf47
chromosome 6 open reading frame 47
chr7_-_102158157 0.061 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
 RASA4B


RAS p21 protein activator 4B


chr7_+_156433363 0.058 ENST00000439609.1
 RNF32
ring finger protein 32
chr18_+_32073839 0.058 ENST00000590412.1
 DTNA
dystrobrevin, alpha
chr5_+_156569944 0.057 ENST00000521769.1
 ITK
IL2-inducible T-cell kinase
chr16_+_31724618 0.057 ENST00000530881.1
ENST00000529515.1
 ZNF720

zinc finger protein 720

chr1_+_154909803 0.057 ENST00000604546.1
 RP11-307C12.13
RP11-307C12.13
chr17_+_41994576 0.057 ENST00000588043.2
 FAM215A
family with sequence similarity 215, member A (non-protein coding)
chr10_+_54074033 0.056 ENST00000373970.3
 DKK1
dickkopf WNT signaling pathway inhibitor 1
chr7_-_102257139 0.055 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
 RASA4




RAS p21 protein activator 4




chr1_+_6640108 0.054 ENST00000377674.4
ENST00000488936.1
 ZBTB48

zinc finger and BTB domain containing 48

chr10_-_50970382 0.053 ENST00000419399.1
ENST00000432695.1
 OGDHL

oxoglutarate dehydrogenase-like

chr1_+_6640046 0.052 ENST00000319084.5
ENST00000435905.1
 ZBTB48

zinc finger and BTB domain containing 48

chr3_-_25915189 0.052 ENST00000451284.1
 LINC00692
long intergenic non-protein coding RNA 692
chr19_+_35773242 0.051 ENST00000222304.3
 HAMP
hepcidin antimicrobial peptide
chr14_-_50559361 0.050 ENST00000305273.1
 C14orf183
chromosome 14 open reading frame 183
chr7_+_1609765 0.049 ENST00000437964.1
ENST00000533935.1
ENST00000532358.1
ENST00000524978.1
 PSMG3-AS1



PSMG3 antisense RNA 1 (head to head)



chr18_-_21166841 0.049 ENST00000269228.5
 NPC1
Niemann-Pick disease, type C1
chr21_-_34863693 0.048 ENST00000314399.3
 DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr21_-_16125773 0.048 ENST00000454128.2
 AF127936.3
AF127936.3
chr16_+_28858004 0.048 ENST00000322610.8
 SH2B1
SH2B adaptor protein 1
chr5_-_156569754 0.047 ENST00000420343.1
 MED7
mediator complex subunit 7
chr1_-_15850676 0.046 ENST00000440484.1
ENST00000333868.5
 CASP9

caspase 9, apoptosis-related cysteine peptidase

chr9_+_95858485 0.044 ENST00000375464.2
 C9orf89
chromosome 9 open reading frame 89
chr8_-_41166953 0.044 ENST00000220772.3
 SFRP1
secreted frizzled-related protein 1
chr21_-_16126181 0.044 ENST00000455253.2
 AF127936.3
AF127936.3
chr16_+_28985542 0.043 ENST00000567771.1
ENST00000568388.1
 SPNS1

spinster homolog 1 (Drosophila)

chr6_+_126102292 0.043 ENST00000368357.3
 NCOA7
nuclear receptor coactivator 7
chr1_+_171454639 0.042 ENST00000392078.3
ENST00000426496.2
 PRRC2C

proline-rich coiled-coil 2C

chr3_-_19975665 0.042 ENST00000295824.9
ENST00000389256.4
 EFHB

EF-hand domain family, member B

chr3_+_190105909 0.041 ENST00000456423.1
 CLDN16
claudin 16
chr3_+_179040767 0.040 ENST00000496856.1
ENST00000491818.1
 ZNF639

zinc finger protein 639

chr5_-_127418573 0.040 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
 CTC-228N24.3



CTC-228N24.3



chr12_+_10331605 0.040 ENST00000298530.3
 TMEM52B
transmembrane protein 52B
chr10_-_50970322 0.040 ENST00000374103.4
 OGDHL
oxoglutarate dehydrogenase-like
chr16_+_31724552 0.039 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
 ZNF720




zinc finger protein 720




chr4_+_26862313 0.038 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
 STIM2


stromal interaction molecule 2


chr5_-_127418755 0.038 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
 CTC-228N24.3




CTC-228N24.3




chr2_+_131862900 0.037 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
 PLEKHB2


pleckstrin homology domain containing, family B (evectins) member 2


chr11_+_73359936 0.037 ENST00000542389.1
 PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_49019061 0.036 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
 MAGIX



MAGI family member, X-linked



chr1_-_182369751 0.036 ENST00000367565.1
 TEDDM1
transmembrane epididymal protein 1
chr6_+_168196210 0.036 ENST00000597278.1
 AL009178.1
Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793
chr7_+_48128316 0.035 ENST00000341253.4
 UPP1
uridine phosphorylase 1
chr10_+_30722866 0.035 ENST00000263056.1
 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr7_+_48128194 0.034 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
 UPP1


uridine phosphorylase 1


chr12_-_46766577 0.034 ENST00000256689.5
 SLC38A2
solute carrier family 38, member 2
chr4_+_26862431 0.034 ENST00000465503.1
 STIM2
stromal interaction molecule 2
chr11_-_73882249 0.033 ENST00000535954.1
 C2CD3
C2 calcium-dependent domain containing 3
chr1_+_171454659 0.033 ENST00000367742.3
ENST00000338920.4
 PRRC2C

proline-rich coiled-coil 2C

chr14_-_105420241 0.033 ENST00000557457.1
 AHNAK2
AHNAK nucleoprotein 2
chr1_+_95975672 0.033 ENST00000440116.2
ENST00000456933.1
 RP11-286B14.1

RP11-286B14.1

chr4_+_26862400 0.032 ENST00000467011.1
ENST00000412829.2
 STIM2

stromal interaction molecule 2

chr6_+_111580508 0.032 ENST00000368847.4
 KIAA1919
KIAA1919
chr11_+_73360024 0.031 ENST00000540431.1
 PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr16_+_58059470 0.031 ENST00000219271.3
 MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr2_+_131862872 0.030 ENST00000439822.2
 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr14_-_35183755 0.030 ENST00000555765.1
 CFL2
cofilin 2 (muscle)
chr7_+_150759634 0.030 ENST00000392826.2
ENST00000461735.1
 SLC4A2

solute carrier family 4 (anion exchanger), member 2

chr19_-_44809121 0.030 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
 ZNF235



zinc finger protein 235



chr2_-_122262593 0.029 ENST00000418989.1
 CLASP1
cytoplasmic linker associated protein 1
chrX_+_57618269 0.028 ENST00000374888.1
 ZXDB
zinc finger, X-linked, duplicated B
chr18_+_60190226 0.028 ENST00000269499.5
 ZCCHC2
zinc finger, CCHC domain containing 2
chr8_-_13134045 0.028 ENST00000512044.2
 DLC1
deleted in liver cancer 1
chr10_-_52008313 0.028 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
 ASAH2


N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2


chr17_-_36904437 0.027 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
 PCGF2



polycomb group ring finger 2



chr1_-_15850839 0.027 ENST00000348549.5
ENST00000546424.1
 CASP9

caspase 9, apoptosis-related cysteine peptidase

chr11_+_57308979 0.026 ENST00000457912.1
 SMTNL1
smoothelin-like 1
chr7_+_47834880 0.026 ENST00000258776.4
 C7orf69
chromosome 7 open reading frame 69
chr8_-_37824442 0.025 ENST00000345060.3
 ADRB3
adrenoceptor beta 3
chr11_-_111749767 0.025 ENST00000542429.1
 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr10_+_32735030 0.025 ENST00000277657.6
ENST00000362006.5
 CCDC7

coiled-coil domain containing 7

chr7_+_64254793 0.025 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
 ZNF138



zinc finger protein 138



chr1_-_154909329 0.025 ENST00000368467.3
 PMVK
phosphomevalonate kinase
chr6_+_28227063 0.025 ENST00000343684.3
 NKAPL
NFKB activating protein-like
chrY_+_20708557 0.025 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
 HSFY1


heat shock transcription factor, Y-linked 1


chr11_+_86106208 0.023 ENST00000528728.1
 CCDC81
coiled-coil domain containing 81
chr7_-_91509972 0.023 ENST00000425936.1
 MTERF
mitochondrial transcription termination factor
chr18_-_2571437 0.023 ENST00000574676.1
ENST00000574538.1
ENST00000319888.6
 METTL4


methyltransferase like 4


chr19_-_12267524 0.023 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
 ZNF625



zinc finger protein 625



chr4_-_48683188 0.023 ENST00000505759.1
 FRYL
FRY-like
chr11_-_111749878 0.023 ENST00000260257.4
 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr12_-_51418549 0.022 ENST00000548150.1
 SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr19_+_52255261 0.022 ENST00000600258.1
 FPR2
formyl peptide receptor 2
chr1_-_76398077 0.022 ENST00000284142.6
 ASB17
ankyrin repeat and SOCS box containing 17
chr16_+_57279248 0.022 ENST00000562023.1
ENST00000563234.1
 ARL2BP

ADP-ribosylation factor-like 2 binding protein

chr19_-_53324884 0.021 ENST00000457749.2
ENST00000414252.2
ENST00000391783.2
 ZNF28


zinc finger protein 28


chr8_-_135652051 0.021 ENST00000522257.1
 ZFAT
zinc finger and AT hook domain containing
chr10_+_30723105 0.021 ENST00000375322.2
 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr18_-_2571210 0.021 ENST00000577166.1
 METTL4
methyltransferase like 4
chr19_-_9546177 0.020 ENST00000592292.1
ENST00000588221.1
 ZNF266

zinc finger protein 266

chr3_-_18487057 0.020 ENST00000415069.1
 SATB1
SATB homeobox 1
chr19_-_40732594 0.020 ENST00000430325.2
ENST00000433940.1
 CNTD2

cyclin N-terminal domain containing 2

chr5_+_154320623 0.019 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
 MRPL22



mitochondrial ribosomal protein L22



chr6_-_28226984 0.019 ENST00000423974.2
 ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr9_+_75136717 0.019 ENST00000297784.5
 TMC1
transmembrane channel-like 1
chr4_+_48807155 0.019 ENST00000504654.1
 OCIAD1
OCIA domain containing 1
chr5_-_180688105 0.019 ENST00000327767.4
 TRIM52
tripartite motif containing 52
chr5_-_131892501 0.019 ENST00000450655.1
 IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chrX_+_27608517 0.019 ENST00000431122.2
 DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr16_+_57279004 0.019 ENST00000219204.3
 ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr3_-_46875585 0.019 ENST00000429665.1
 PRSS42
protease, serine, 42
chr19_-_9546227 0.018 ENST00000361451.2
ENST00000361151.1
 ZNF266

zinc finger protein 266

chr1_+_179263308 0.018 ENST00000426956.1
 SOAT1
sterol O-acyltransferase 1
chr18_+_29769978 0.018 ENST00000269202.6
ENST00000581447.1
 MEP1B

meprin A, beta

chr4_-_170947565 0.018 ENST00000506764.1
 MFAP3L
microfibrillar-associated protein 3-like
chr17_+_36908984 0.018 ENST00000225426.4
ENST00000579088.1
 PSMB3

proteasome (prosome, macropain) subunit, beta type, 3

chr1_+_104068312 0.018 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
 RNPC3



RNA-binding region (RNP1, RRM) containing 3



chr8_+_110552046 0.018 ENST00000529931.1
 EBAG9
estrogen receptor binding site associated, antigen, 9
chrX_-_53461305 0.018 ENST00000168216.6
 HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr12_+_20522179 0.017 ENST00000359062.3
 PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr11_-_73882029 0.017 ENST00000539061.1
 C2CD3
C2 calcium-dependent domain containing 3
chr10_+_32735177 0.016 ENST00000545067.1
 CCDC7
coiled-coil domain containing 7
chr19_+_53073526 0.016 ENST00000596514.1
ENST00000391785.3
ENST00000301093.2
 ZNF701


zinc finger protein 701


chr1_-_211307404 0.016 ENST00000367007.4
 KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr1_+_35544968 0.016 ENST00000359858.4
ENST00000373330.1
 ZMYM1

zinc finger, MYM-type 1

chr3_-_196014520 0.016 ENST00000441879.1
ENST00000292823.2
ENST00000411591.1
ENST00000431016.1
ENST00000443555.1
 PCYT1A




phosphate cytidylyltransferase 1, choline, alpha




chr6_+_37321748 0.016 ENST00000373479.4
ENST00000394443.4
 RNF8

ring finger protein 8, E3 ubiquitin protein ligase

chr11_+_28131821 0.016 ENST00000379199.2
ENST00000303459.6
 METTL15

methyltransferase like 15

chr16_-_21442874 0.016 ENST00000534903.1
 NPIPB3
nuclear pore complex interacting protein family, member B3
chr16_-_28857677 0.015 ENST00000313511.3
 TUFM
Tu translation elongation factor, mitochondrial
chr2_+_139259324 0.015 ENST00000280098.4
 SPOPL
speckle-type POZ protein-like
chr14_+_73603126 0.015 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
 PSEN1
















presenilin 1
















chr4_-_103747011 0.015 ENST00000350435.7
 UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_-_138348969 0.015 ENST00000436657.1
 SVOPL
SVOP-like
chr1_+_241695670 0.015 ENST00000366557.4
 KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr14_+_45605127 0.015 ENST00000556036.1
ENST00000267430.5
 FANCM

Fanconi anemia, complementation group M

chr1_+_241695424 0.014 ENST00000366558.3
ENST00000366559.4
 KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

chr1_-_109399682 0.014 ENST00000369995.3
ENST00000370001.3
 AKNAD1

AKNA domain containing 1

chr14_+_45605157 0.014 ENST00000542564.2
 FANCM
Fanconi anemia, complementation group M
chr11_-_61062762 0.014 ENST00000335613.5
 VWCE
von Willebrand factor C and EGF domains
chr6_-_8102279 0.014 ENST00000488226.2
 EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr6_+_37321823 0.014 ENST00000487950.1
ENST00000469731.1
 RNF8

ring finger protein 8, E3 ubiquitin protein ligase

chr1_+_104068562 0.014 ENST00000423855.2
 RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr1_+_179262905 0.014 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
 SOAT1



sterol O-acyltransferase 1



chr6_+_34725263 0.014 ENST00000374018.1
ENST00000374017.3
 SNRPC

small nuclear ribonucleoprotein polypeptide C

chr20_+_17949724 0.013 ENST00000377704.4
 MGME1
mitochondrial genome maintenance exonuclease 1
chr5_+_173473662 0.013 ENST00000519717.1
 NSG2
Neuron-specific protein family member 2
chr1_-_154178803 0.013 ENST00000368525.3
 C1orf189
chromosome 1 open reading frame 189
chr1_+_26759295 0.013 ENST00000430232.1
 DHDDS
dehydrodolichyl diphosphate synthase
chrX_+_27608490 0.013 ENST00000451261.2
 DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chrY_-_20935572 0.013 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
 HSFY2


heat shock transcription factor, Y linked 2


chr17_-_38074859 0.013 ENST00000520542.1
ENST00000418519.1
ENST00000394179.1
 GSDMB


gasdermin B


chr1_+_150980989 0.013 ENST00000368935.1
 PRUNE
prune exopolyphosphatase
chr14_-_31676964 0.013 ENST00000553700.1
 HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr8_+_117963190 0.013 ENST00000427715.2
 SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr11_-_59383617 0.012 ENST00000263847.1
 OSBP
oxysterol binding protein
chr8_+_110552831 0.012 ENST00000530629.1
 EBAG9
estrogen receptor binding site associated, antigen, 9
chr5_+_162930114 0.012 ENST00000280969.5
 MAT2B
methionine adenosyltransferase II, beta
chr9_-_130890662 0.012 ENST00000277462.5
ENST00000338961.6
 PTGES2

prostaglandin E synthase 2

chr11_-_82997013 0.012 ENST00000529073.1
ENST00000529611.1
 CCDC90B

coiled-coil domain containing 90B

chr22_-_45559540 0.012 ENST00000432502.1
 CTA-217C2.1
CTA-217C2.1
chr4_+_128886584 0.012 ENST00000513371.1
 C4orf29
chromosome 4 open reading frame 29
chr5_+_145826867 0.012 ENST00000296702.5
ENST00000394421.2
 TCERG1

transcription elongation regulator 1

chr16_+_28857957 0.012 ENST00000567536.1
 SH2B1
SH2B adaptor protein 1
chr4_-_159592996 0.012 ENST00000508457.1
 C4orf46
chromosome 4 open reading frame 46
chr3_-_112218378 0.012 ENST00000334529.5
 BTLA
B and T lymphocyte associated
chr4_+_4861385 0.011 ENST00000382723.4
 MSX1
msh homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0002856 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006218 uridine catabolic process(GO:0006218)
0.0 0.1 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.0 0.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors