Motif ID: PRDM4

Z-value: 0.305


Transcription factors associated with PRDM4:

Gene SymbolEntrez IDGene Name
PRDM4 ENSG00000110851.7 PRDM4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_1081549450.882.0e-03Click!


Activity profile for motif PRDM4.

activity profile for motif PRDM4


Sorted Z-values histogram for motif PRDM4

Sorted Z-values for motif PRDM4



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_88728189 0.264 ENST00000416348.1
 ADIRF
adipogenesis regulatory factor
chr7_+_90893783 0.180 ENST00000287934.2
 FZD1
frizzled family receptor 1
chr14_-_24732738 0.171 ENST00000558074.1
ENST00000560226.1
 TGM1

transglutaminase 1

chr10_-_105212141 0.155 ENST00000369788.3
 CALHM2
calcium homeostasis modulator 2
chr12_+_104682667 0.153 ENST00000527335.1
 TXNRD1
thioredoxin reductase 1
chr7_-_45906045 0.146 ENST00000596600.1
 AC096582.1
Uncharacterized protein
chr12_+_104682496 0.136 ENST00000378070.4
 TXNRD1
thioredoxin reductase 1
chr6_+_26045603 0.117 ENST00000540144.1
 HIST1H3C
histone cluster 1, H3c
chrX_-_73072534 0.116 ENST00000429829.1
 XIST
X inactive specific transcript (non-protein coding)
chr5_-_78281623 0.114 ENST00000521117.1
 ARSB
arylsulfatase B
chr5_+_145317356 0.110 ENST00000511217.1
 SH3RF2
SH3 domain containing ring finger 2
chr19_-_35264089 0.098 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
 ZNF599


zinc finger protein 599


chr2_+_233734994 0.094 ENST00000331342.2
 C2orf82
chromosome 2 open reading frame 82
chr1_-_68516393 0.091 ENST00000395201.1
 DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr1_-_43232649 0.083 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
 LEPRE1



leucine proline-enriched proteoglycan (leprecan) 1



chr3_-_169381166 0.074 ENST00000486748.1
 MECOM
MDS1 and EVI1 complex locus
chr14_+_105953204 0.074 ENST00000409393.2
 CRIP1
cysteine-rich protein 1 (intestinal)
chr8_+_91952750 0.073 ENST00000521366.1
 NECAB1
N-terminal EF-hand calcium binding protein 1
chr5_-_102455801 0.070 ENST00000508629.1
ENST00000399004.2
 GIN1

gypsy retrotransposon integrase 1

chr14_+_105953246 0.069 ENST00000392531.3
 CRIP1
cysteine-rich protein 1 (intestinal)
chr6_-_24721054 0.066 ENST00000378119.4
 C6orf62
chromosome 6 open reading frame 62
chr8_-_135652051 0.059 ENST00000522257.1
 ZFAT
zinc finger and AT hook domain containing
chr2_-_179343226 0.059 ENST00000434643.2
 FKBP7
FK506 binding protein 7
chr2_-_179343268 0.057 ENST00000424785.2
 FKBP7
FK506 binding protein 7
chr5_-_78281775 0.056 ENST00000396151.3
ENST00000565165.1
 ARSB

arylsulfatase B

chr1_+_54359854 0.054 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
 DIO1





deiodinase, iodothyronine, type I





chrX_+_15808569 0.051 ENST00000380308.3
ENST00000307771.7
 ZRSR2

zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

chr2_+_234296792 0.049 ENST00000409813.3
 DGKD
diacylglycerol kinase, delta 130kDa
chr5_+_159343688 0.049 ENST00000306675.3
 ADRA1B
adrenoceptor alpha 1B
chr5_-_78281603 0.049 ENST00000264914.4
 ARSB
arylsulfatase B
chr2_-_8723918 0.048 ENST00000454224.1
 AC011747.4
AC011747.4
chr14_+_24025345 0.047 ENST00000557630.1
 THTPA
thiamine triphosphatase
chr2_+_219264762 0.047 ENST00000452977.1
 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_-_53636125 0.043 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
 ZNF415














zinc finger protein 415














chr14_+_24025194 0.042 ENST00000404535.3
ENST00000288014.6
 THTPA

thiamine triphosphatase

chr1_-_35497283 0.041 ENST00000373333.1
 ZMYM6
zinc finger, MYM-type 6
chr4_+_667686 0.040 ENST00000505477.1
 MYL5
myosin, light chain 5, regulatory
chr17_-_9929581 0.040 ENST00000437099.2
ENST00000396115.2
 GAS7

growth arrest-specific 7

chr10_+_123923105 0.039 ENST00000368999.1
 TACC2
transforming, acidic coiled-coil containing protein 2
chr16_+_29674540 0.036 ENST00000449759.1
ENST00000436527.1
ENST00000360121.3
 QPRT
SPN

quinolinate phosphoribosyltransferase
sialophorin

chr12_+_80838126 0.036 ENST00000266688.5
 PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr2_+_219264466 0.035 ENST00000273062.2
 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr5_-_180688105 0.034 ENST00000327767.4
 TRIM52
tripartite motif containing 52
chr16_+_15068916 0.033 ENST00000455313.2
 PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr16_+_15068831 0.032 ENST00000535621.2
ENST00000566426.1
 PDXDC1

pyridoxal-dependent decarboxylase domain containing 1

chr1_+_172502336 0.026 ENST00000263688.3
 SUCO
SUN domain containing ossification factor
chr1_+_172502244 0.025 ENST00000610051.1
 SUCO
SUN domain containing ossification factor
chr5_+_140261703 0.024 ENST00000409494.1
ENST00000289272.2
 PCDHA13

protocadherin alpha 13

chr1_+_27113963 0.021 ENST00000430292.1
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr7_+_143078652 0.018 ENST00000354434.4
ENST00000449423.2
 ZYX

zyxin

chr4_+_667307 0.017 ENST00000506838.1
 MYL5
myosin, light chain 5, regulatory
chr20_-_61569296 0.016 ENST00000370371.4
 DIDO1
death inducer-obliterator 1
chr16_+_29823552 0.016 ENST00000300797.6
 PRRT2
proline-rich transmembrane protein 2
chr14_+_32030582 0.015 ENST00000550649.1
ENST00000281081.7
 NUBPL

nucleotide binding protein-like

chr5_+_102455853 0.014 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
 PPIP5K2


diphosphoinositol pentakisphosphate kinase 2


chr16_+_29823427 0.011 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
 PRRT2


proline-rich transmembrane protein 2


chr1_+_43232913 0.011 ENST00000372525.5
ENST00000536543.1
 C1orf50

chromosome 1 open reading frame 50

chr5_+_102455968 0.011 ENST00000358359.3
 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr9_+_17135016 0.011 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
 CNTLN


centlein, centrosomal protein


chr7_+_143079000 0.010 ENST00000392910.2
 ZYX
zyxin
chr16_+_15068955 0.008 ENST00000396410.4
ENST00000569715.1
ENST00000450288.2
 PDXDC1


pyridoxal-dependent decarboxylase domain containing 1


chr12_+_50794947 0.008 ENST00000552445.1
 LARP4
La ribonucleoprotein domain family, member 4
chr14_+_64565442 0.006 ENST00000553308.1
 SYNE2
spectrin repeat containing, nuclear envelope 2
chr1_+_171750776 0.006 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
 METTL13



methyltransferase like 13



chr1_-_161168834 0.006 ENST00000367995.3
ENST00000367996.5
 ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

chr14_-_74462922 0.004 ENST00000553284.1
 ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr20_-_61569227 0.003 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
 DIDO1


death inducer-obliterator 1


chr12_-_58240470 0.002 ENST00000548823.1
ENST00000398073.2
 CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr11_+_47279504 0.001 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
 NR1H3




nuclear receptor subfamily 1, group H, member 3




chr4_-_83295103 0.001 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
 HNRNPD




heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)




chr6_-_8064567 0.001 ENST00000543936.1
ENST00000397457.2
 BLOC1S5

biogenesis of lysosomal organelles complex-1, subunit 5, muted

chr4_-_83295296 0.001 ENST00000507010.1
ENST00000503822.1
 HNRNPD

heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.3 GO:2001023 cellular response to cisplatin(GO:0072719) regulation of response to drug(GO:2001023)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases