Motif ID: PPARA

Z-value: 0.611


Transcription factors associated with PPARA:

Gene SymbolEntrez IDGene Name
PPARA ENSG00000186951.12 PPARA

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PPARAhg19_v2_chr22_+_46546494_46546525-0.853.9e-03Click!


Activity profile for motif PPARA.

activity profile for motif PPARA


Sorted Z-values histogram for motif PPARA

Sorted Z-values for motif PPARA



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_151619746 1.138 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr12_+_93963590 0.773 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr18_-_56296182 0.755 ENST00000361673.3
ALPK2
alpha-kinase 2
chr19_-_39826639 0.716 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr12_+_54378923 0.658 ENST00000303460.4
HOXC10
homeobox C10
chr13_-_46756351 0.655 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_+_103046954 0.620 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr17_+_74536115 0.618 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr19_-_51192661 0.605 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr15_+_59730348 0.564 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chr6_+_13272904 0.528 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chrX_-_31285042 0.518 ENST00000378680.2
ENST00000378723.3
DMD

dystrophin

chr9_-_33402506 0.499 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr20_+_1875378 0.485 ENST00000356025.3
SIRPA
signal-regulatory protein alpha
chr17_+_48046671 0.472 ENST00000505318.2
DLX4
distal-less homeobox 4
chr20_+_1875110 0.463 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr20_+_1875942 0.450 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr12_+_93964158 0.449 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr5_+_149569520 0.443 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr1_-_156786634 0.442 ENST00000392306.2
ENST00000368199.3
SH2D2A

SH2 domain containing 2A

chr19_-_55669093 0.439 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chrX_+_16668278 0.436 ENST00000380200.3
S100G
S100 calcium binding protein G
chr1_-_156786530 0.433 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr17_+_74536164 0.431 ENST00000586148.1
PRCD
progressive rod-cone degeneration
chr12_+_54378849 0.429 ENST00000515593.1
HOXC10
homeobox C10
chr17_+_48046538 0.426 ENST00000240306.3
DLX4
distal-less homeobox 4
chr2_+_220491973 0.412 ENST00000358055.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr22_+_31518938 0.411 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chrX_-_31285018 0.408 ENST00000361471.4
DMD
dystrophin
chr22_+_21321531 0.404 ENST00000405089.1
ENST00000335375.5
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr12_+_72667203 0.402 ENST00000547300.1
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr12_+_54384370 0.395 ENST00000504315.1
HOXC6
homeobox C6
chr10_+_77056181 0.370 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1

ZNF503 antisense RNA 1

chrX_-_31284974 0.364 ENST00000378702.4
DMD
dystrophin
chr7_+_100187196 0.360 ENST00000468962.1
ENST00000427939.2
FBXO24

F-box protein 24

chr5_+_135383008 0.357 ENST00000508767.1
ENST00000604555.1
TGFBI

transforming growth factor, beta-induced, 68kDa

chr17_-_56405407 0.349 ENST00000343736.4
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chrX_+_70521584 0.338 ENST00000373829.3
ENST00000538820.1
ITGB1BP2

integrin beta 1 binding protein (melusin) 2

chr7_-_27196267 0.326 ENST00000242159.3
HOXA7
homeobox A7
chr5_-_19988288 0.321 ENST00000502796.1
ENST00000511273.1
CDH18

cadherin 18, type 2

chrX_+_135230712 0.319 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr22_-_33968239 0.318 ENST00000452586.2
ENST00000421768.1
LARGE

like-glycosyltransferase

chr17_-_46671323 0.313 ENST00000239151.5
HOXB5
homeobox B5
chr4_-_186732048 0.306 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr13_-_33859819 0.305 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_-_186696425 0.303 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr8_+_104831554 0.303 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_77056134 0.302 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr22_+_21321447 0.298 ENST00000434714.1
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr4_-_186696561 0.297 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chrX_-_133792480 0.295 ENST00000359237.4
PLAC1
placenta-specific 1
chr17_-_7123021 0.290 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr5_-_19988339 0.286 ENST00000382275.1
CDH18
cadherin 18, type 2
chr14_+_76776957 0.286 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr3_-_113465065 0.280 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr17_+_9548845 0.276 ENST00000570475.1
ENST00000285199.7
USP43

ubiquitin specific peptidase 43

chr2_-_99871570 0.271 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2


lysozyme G-like 2


chr6_+_90272488 0.271 ENST00000485637.1
ENST00000522705.1
ANKRD6

ankyrin repeat domain 6

chr8_-_144651024 0.269 ENST00000524906.1
ENST00000532862.1
ENST00000534459.1
MROH6


maestro heat-like repeat family member 6


chr20_+_31499459 0.266 ENST00000439060.1
EFCAB8
EF-hand calcium binding domain 8
chr16_+_58535372 0.265 ENST00000566656.1
ENST00000566618.1
NDRG4

NDRG family member 4

chr12_+_6930703 0.263 ENST00000311268.3
GPR162
G protein-coupled receptor 162
chr13_+_32605437 0.257 ENST00000380250.3
FRY
furry homolog (Drosophila)
chr4_-_186696515 0.257 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr13_-_33760216 0.253 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_58159361 0.251 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr14_-_80677970 0.248 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr11_+_7618413 0.246 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_+_6930964 0.246 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr14_-_80677815 0.245 ENST00000557125.1
ENST00000555750.1
DIO2

deiodinase, iodothyronine, type II

chr12_+_6930813 0.245 ENST00000428545.2
GPR162
G protein-coupled receptor 162
chr2_-_74667612 0.244 ENST00000305557.5
ENST00000233330.6
RTKN

rhotekin

chr21_-_32931290 0.237 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr15_+_23810903 0.231 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr16_-_88717423 0.228 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA


cytochrome b-245, alpha polypeptide


chr10_-_17171785 0.226 ENST00000377823.1
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr17_-_2169425 0.223 ENST00000570606.1
ENST00000354901.4
SMG6

SMG6 nonsense mediated mRNA decay factor

chr3_-_113464906 0.223 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_-_186696636 0.221 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr13_-_31191642 0.217 ENST00000405805.1
HMGB1
high mobility group box 1
chr15_-_78423567 0.216 ENST00000561190.1
ENST00000559645.1
ENST00000560618.1
ENST00000559054.1
CIB2



calcium and integrin binding family member 2



chr2_+_220492287 0.213 ENST00000273063.6
ENST00000373762.3
SLC4A3

solute carrier family 4 (anion exchanger), member 3

chr22_+_31523734 0.210 ENST00000402238.1
ENST00000404453.1
ENST00000401755.1
INPP5J


inositol polyphosphate-5-phosphatase J


chr17_-_7082861 0.207 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr14_-_80677613 0.204 ENST00000556811.1
DIO2
deiodinase, iodothyronine, type II
chr5_+_162887556 0.201 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR


hyaluronan-mediated motility receptor (RHAMM)


chr10_-_17171817 0.201 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr16_+_28303804 0.200 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr3_-_50340996 0.199 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1





hyaluronoglucosaminidase 1





chr11_-_63684316 0.197 ENST00000301459.4
RCOR2
REST corepressor 2
chr15_-_72767490 0.193 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr11_+_10472223 0.193 ENST00000396554.3
ENST00000524866.1
AMPD3

adenosine monophosphate deaminase 3

chr2_+_73441350 0.193 ENST00000389501.4
SMYD5
SMYD family member 5
chr21_+_17566643 0.191 ENST00000419952.1
ENST00000445461.2
LINC00478

long intergenic non-protein coding RNA 478

chr12_+_54426637 0.190 ENST00000312492.2
HOXC5
homeobox C5
chr17_-_39258461 0.188 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr3_-_52486841 0.188 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr19_-_11308190 0.186 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr6_+_151358048 0.185 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr9_-_35685452 0.184 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr19_-_49552006 0.182 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr14_+_42076765 0.182 ENST00000298119.4
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr8_+_77318769 0.181 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr1_-_235116495 0.181 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr2_+_220492116 0.180 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr14_+_37126765 0.179 ENST00000402703.2
PAX9
paired box 9
chr1_+_176432298 0.178 ENST00000367661.3
ENST00000367662.3
PAPPA2

pappalysin 2

chr13_+_51913819 0.177 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr15_+_65337708 0.176 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr11_+_66624527 0.176 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr8_+_101349823 0.176 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr22_+_47158578 0.176 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr19_-_49552363 0.174 ENST00000448456.3
ENST00000355414.2
CGB8

chorionic gonadotropin, beta polypeptide 8

chr13_-_95131923 0.174 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr19_-_6433765 0.173 ENST00000321510.6
SLC25A41
solute carrier family 25, member 41
chr12_-_110011288 0.169 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr1_-_205719295 0.168 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr19_+_49547099 0.167 ENST00000301408.6
CGB5
chorionic gonadotropin, beta polypeptide 5
chr4_-_186732241 0.167 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_131299929 0.166 ENST00000531356.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_-_55881741 0.166 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11


interleukin 11


chr16_+_777739 0.164 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr11_+_46740730 0.163 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2


coagulation factor II (thrombin)


chr22_+_37959647 0.162 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr2_+_220492373 0.161 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr16_+_680932 0.160 ENST00000319070.2
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr1_-_103574024 0.159 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1



collagen, type XI, alpha 1



chr19_+_54466179 0.158 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr20_-_30458354 0.158 ENST00000428829.1
DUSP15
dual specificity phosphatase 15
chr2_-_208031943 0.156 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr18_-_22804637 0.156 ENST00000577775.1
ZNF521
zinc finger protein 521
chr3_+_189349162 0.156 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63





chr18_-_44336754 0.155 ENST00000538168.1
ENST00000536490.1
ST8SIA5

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5

chr14_+_21566980 0.154 ENST00000418511.2
ENST00000554329.2
TMEM253

transmembrane protein 253

chr3_-_45957088 0.154 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr11_+_278365 0.154 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr15_+_82555125 0.154 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr11_+_73498973 0.154 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr11_+_86749035 0.152 ENST00000305494.5
ENST00000535167.1
TMEM135

transmembrane protein 135

chr3_-_45957534 0.152 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr12_+_58013693 0.150 ENST00000320442.4
ENST00000379218.2
SLC26A10

solute carrier family 26, member 10

chr12_+_120875910 0.149 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr9_-_127358087 0.149 ENST00000475178.1
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr2_-_208031542 0.148 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_-_101351184 0.148 ENST00000534062.1
RTL1
retrotransposon-like 1
chrX_-_40036520 0.148 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
BCOR


BCL6 corepressor


chr11_+_73498898 0.147 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48





mitochondrial ribosomal protein L48





chr1_-_9563433 0.147 ENST00000441033.1
RP13-392I16.1
RP13-392I16.1
chr16_-_72206034 0.146 ENST00000537465.1
ENST00000237353.10
PMFBP1

polyamine modulated factor 1 binding protein 1

chr3_+_138340067 0.146 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr11_+_86748863 0.144 ENST00000340353.7
TMEM135
transmembrane protein 135
chr15_+_35838446 0.143 ENST00000559210.1
DPH6-AS1
DPH6 antisense RNA 1 (head to head)
chr5_+_156712372 0.143 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_241520525 0.143 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr11_+_86748957 0.141 ENST00000526733.1
ENST00000532959.1
TMEM135

transmembrane protein 135

chr3_+_159557637 0.140 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr12_-_121973974 0.138 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B


lysine (K)-specific demethylase 2B


chr22_-_29711645 0.137 ENST00000401450.3
RASL10A
RAS-like, family 10, member A
chr17_+_7348374 0.136 ENST00000306071.2
ENST00000572857.1
CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

chr3_-_42845951 0.134 ENST00000418900.2
ENST00000430190.1
HIGD1A

HIG1 hypoxia inducible domain family, member 1A

chr20_+_37590942 0.134 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr1_+_45274154 0.133 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr15_+_35838396 0.133 ENST00000501169.2
DPH6-AS1
DPH6 antisense RNA 1 (head to head)
chr22_-_29711704 0.131 ENST00000216101.6
RASL10A
RAS-like, family 10, member A
chr15_+_58724184 0.130 ENST00000433326.2
LIPC
lipase, hepatic
chr12_-_6665200 0.130 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1


intermediate filament family orphan 1


chr1_-_150693318 0.130 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1




HORMA domain containing 1




chr12_+_122064398 0.129 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr3_+_138340049 0.129 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr22_+_47158518 0.128 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1D22A


TBC1 domain family, member 22A


chr15_+_75335604 0.127 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr13_+_47127322 0.127 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr11_+_10471836 0.126 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr6_-_131211534 0.126 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr13_+_47127293 0.126 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr17_+_7123125 0.125 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL


acyl-CoA dehydrogenase, very long chain


chr7_-_111424462 0.125 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr6_+_72922505 0.125 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_123339418 0.124 ENST00000583087.1
MYLK
myosin light chain kinase
chr3_-_46000064 0.124 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr16_-_58328923 0.124 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54


protease, serine, 54


chr1_-_241520385 0.124 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr13_+_76123883 0.123 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr17_-_38821373 0.123 ENST00000394052.3
KRT222
keratin 222
chr1_-_238108575 0.123 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr12_-_120554534 0.122 ENST00000538903.1
ENST00000534951.1
RAB35

RAB35, member RAS oncogene family

chr3_-_42845922 0.122 ENST00000452906.2
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr7_-_111424506 0.122 ENST00000450156.1
ENST00000494651.2
DOCK4

dedicator of cytokinesis 4

chrX_-_21776281 0.122 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr17_+_7123207 0.122 ENST00000584103.1
ENST00000579886.2
ACADVL

acyl-CoA dehydrogenase, very long chain

chr12_-_124873357 0.121 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr2_+_74757050 0.121 ENST00000352222.3
ENST00000437202.1
HTRA2

HtrA serine peptidase 2

chr22_+_23237555 0.121 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr3_-_27498235 0.121 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chr1_+_218683438 0.121 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr19_+_1041212 0.121 ENST00000433129.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr13_+_47127395 0.120 ENST00000389797.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr19_+_1407517 0.120 ENST00000336761.6
ENST00000233078.4
DAZAP1

DAZ associated protein 1

chr13_-_51417812 0.120 ENST00000504404.1
DLEU7
deleted in lymphocytic leukemia, 7
chr6_+_72922590 0.120 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0050894 determination of affect(GO:0050894)
0.1 0.3 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 1.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.2 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 1.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.7 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.0 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0060414 tonic smooth muscle contraction(GO:0014820) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:1900085 angiotensin-activated signaling pathway involved in heart process(GO:0086098) negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.0 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.3 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.0 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.3 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 1.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031877 somatostatin receptor binding(GO:0031877)
0.2 1.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.6 GO:0031014 troponin T binding(GO:0031014)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0004040 amidase activity(GO:0004040)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.6 ST_GA12_PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 1.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling