Motif ID: POU4F2

Z-value: 0.430


Transcription factors associated with POU4F2:

Gene SymbolEntrez IDGene Name
POU4F2 ENSG00000151615.3 POU4F2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU4F2hg19_v2_chr4_+_147560042_1475600460.029.6e-01Click!


Activity profile for motif POU4F2.

activity profile for motif POU4F2


Sorted Z-values histogram for motif POU4F2

Sorted Z-values for motif POU4F2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU4F2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169013666 0.471 ENST00000359299.3
 ANXA10
annexin A10
chr9_+_125133315 0.431 ENST00000223423.4
ENST00000362012.2
 PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr2_-_70780572 0.357 ENST00000450929.1
 TGFA
transforming growth factor, alpha
chr1_-_47655686 0.337 ENST00000294338.2
 PDZK1IP1
PDZK1 interacting protein 1
chr1_-_44482979 0.247 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr9_+_125132803 0.245 ENST00000540753.1
 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_77230499 0.241 ENST00000396204.2
 RORB
RAR-related orphan receptor B
chr16_+_19421803 0.234 ENST00000541464.1
 TMC5
transmembrane channel-like 5
chr4_-_36245561 0.219 ENST00000506189.1
 ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_-_106146547 0.216 ENST00000276173.4
ENST00000411805.1
 RIPPLY1

ripply transcriptional repressor 1

chr4_+_147145709 0.216 ENST00000504313.1
 RP11-6L6.2
Uncharacterized protein
chr1_-_204183071 0.190 ENST00000308302.3
 GOLT1A
golgi transport 1A
chr8_-_18541603 0.181 ENST00000428502.2
 PSD3
pleckstrin and Sec7 domain containing 3
chr7_+_142982023 0.178 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
 TMEM139



transmembrane protein 139



chr15_-_88247083 0.171 ENST00000560439.1
 RP11-648K4.2
RP11-648K4.2
chr16_+_19422035 0.158 ENST00000381414.4
ENST00000396229.2
 TMC5

transmembrane channel-like 5

chrX_+_139791917 0.152 ENST00000607004.1
ENST00000370535.3
 LINC00632

long intergenic non-protein coding RNA 632

chr18_+_32455201 0.144 ENST00000590831.2
 DTNA
dystrobrevin, alpha
chr12_+_93130311 0.137 ENST00000344636.3
 PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr1_-_31666767 0.134 ENST00000530145.1
 NKAIN1
Na+/K+ transporting ATPase interacting 1
chrX_+_3189861 0.121 ENST00000457435.1
ENST00000420429.2
 CXorf28

chromosome X open reading frame 28

chr6_+_10521574 0.113 ENST00000495262.1
 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr9_+_125133467 0.112 ENST00000426608.1
 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_-_21186144 0.111 ENST00000377119.1
 NEBL
nebulette
chr12_-_52779433 0.090 ENST00000257951.3
 KRT84
keratin 84
chr12_-_130529501 0.087 ENST00000567788.1
ENST00000561864.1
 RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
chr19_-_38344165 0.085 ENST00000592714.1
ENST00000587395.1
 AC016582.2

AC016582.2

chr12_-_89746264 0.085 ENST00000548755.1
 DUSP6
dual specificity phosphatase 6
chr15_-_74421477 0.075 ENST00000514871.1
 RP11-247C2.2
HCG2004779; Uncharacterized protein
chr17_+_61151306 0.074 ENST00000580068.1
ENST00000580466.1
 TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr8_+_7738726 0.073 ENST00000314357.3
 DEFB103A
defensin, beta 103A
chr20_+_56136136 0.073 ENST00000319441.4
ENST00000543666.1
 PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr5_-_87516448 0.067 ENST00000511218.1
 TMEM161B
transmembrane protein 161B
chr17_-_9929581 0.067 ENST00000437099.2
ENST00000396115.2
 GAS7

growth arrest-specific 7

chr22_-_28490123 0.066 ENST00000442232.1
 TTC28
tetratricopeptide repeat domain 28
chr11_+_118175132 0.066 ENST00000361763.4
 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr8_+_22857048 0.064 ENST00000251822.6
 RHOBTB2
Rho-related BTB domain containing 2
chr12_-_89746173 0.062 ENST00000308385.6
 DUSP6
dual specificity phosphatase 6
chr8_-_7287870 0.062 ENST00000318124.3
 DEFB103B
defensin, beta 103B
chr9_-_14308004 0.061 ENST00000493697.1
 NFIB
nuclear factor I/B
chr10_+_123951957 0.049 ENST00000514539.1
 TACC2
transforming, acidic coiled-coil containing protein 2
chr12_+_64798826 0.048 ENST00000540203.1
 XPOT
exportin, tRNA
chr2_+_54951679 0.048 ENST00000356458.6
 EML6
echinoderm microtubule associated protein like 6
chr2_-_158300556 0.047 ENST00000264192.3
 CYTIP
cytohesin 1 interacting protein
chr5_+_102200948 0.047 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
 PAM


peptidylglycine alpha-amidating monooxygenase


chr10_+_95372289 0.046 ENST00000371447.3
 PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr16_+_28505955 0.046 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
 APOBR


apolipoprotein B receptor


chr4_+_169418195 0.045 ENST00000261509.6
ENST00000335742.7
 PALLD

palladin, cytoskeletal associated protein

chr2_+_44502597 0.044 ENST00000260649.6
ENST00000409387.1
 SLC3A1

solute carrier family 3 (amino acid transporter heavy chain), member 1

chr2_-_122262593 0.042 ENST00000418989.1
 CLASP1
cytoplasmic linker associated protein 1
chr11_-_795286 0.040 ENST00000533385.1
ENST00000527723.1
 SLC25A22

solute carrier family 25 (mitochondrial carrier: glutamate), member 22

chr6_+_118869452 0.034 ENST00000357525.5
 PLN
phospholamban
chr14_-_51027838 0.034 ENST00000555216.1
 MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr15_-_98417780 0.033 ENST00000503874.3
 LINC00923
long intergenic non-protein coding RNA 923
chr14_+_38033252 0.030 ENST00000554829.1
 RP11-356O9.1
RP11-356O9.1
chr18_+_74240610 0.030 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
 LINC00908


long intergenic non-protein coding RNA 908


chr1_+_193028717 0.030 ENST00000415442.2
ENST00000506303.1
 TROVE2

TROVE domain family, member 2

chr17_+_73539339 0.029 ENST00000581713.1
 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr1_+_198608146 0.029 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
 PTPRC









protein tyrosine phosphatase, receptor type, C









chr15_+_101402041 0.028 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
 RP11-66B24.1


RP11-66B24.1


chr5_+_147715119 0.028 ENST00000377906.1
 SPINK9
serine peptidase inhibitor, Kazal type 9
chr4_+_169418255 0.027 ENST00000505667.1
ENST00000511948.1
 PALLD

palladin, cytoskeletal associated protein

chr4_-_10686475 0.027 ENST00000226951.6
 CLNK
cytokine-dependent hematopoietic cell linker
chr11_-_96076334 0.027 ENST00000524717.1
 MAML2
mastermind-like 2 (Drosophila)
chr10_-_116444371 0.026 ENST00000533213.2
ENST00000369252.4
 ABLIM1

actin binding LIM protein 1

chr21_+_17443521 0.026 ENST00000456342.1
 LINC00478
long intergenic non-protein coding RNA 478
chr11_-_795170 0.025 ENST00000481290.1
 SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chrX_-_133931164 0.024 ENST00000370790.1
ENST00000298090.6
 FAM122B

family with sequence similarity 122B

chr2_+_44502630 0.023 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
 SLC3A1


solute carrier family 3 (amino acid transporter heavy chain), member 1


chr12_-_30887948 0.022 ENST00000433722.2
 CAPRIN2
caprin family member 2
chr9_+_12685439 0.021 ENST00000473763.1
 TYRP1
tyrosinase-related protein 1
chr4_-_138453606 0.020 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
 PCDH18



protocadherin 18



chr5_-_140998481 0.020 ENST00000518047.1
 DIAPH1
diaphanous-related formin 1
chr12_+_109577202 0.019 ENST00000377848.3
ENST00000377854.5
 ACACB

acetyl-CoA carboxylase beta

chr2_-_198540719 0.019 ENST00000295049.4
 RFTN2
raftlin family member 2
chr20_-_50418972 0.019 ENST00000395997.3
 SALL4
spalt-like transcription factor 4
chr14_-_90085458 0.018 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
 FOXN3


forkhead box N3


chr3_-_58613323 0.017 ENST00000474531.1
ENST00000465970.1
 FAM107A

family with sequence similarity 107, member A

chr2_+_172309634 0.016 ENST00000339506.3
 DCAF17
DDB1 and CUL4 associated factor 17
chr10_+_18549645 0.015 ENST00000396576.2
 CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr11_-_107729887 0.015 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr4_-_169401628 0.012 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
 DDX60L




DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like




chr2_+_191792376 0.010 ENST00000409428.1
ENST00000409215.1
 GLS

glutaminase

chr11_-_107729287 0.010 ENST00000375682.4
 SLC35F2
solute carrier family 35, member F2
chr1_+_40506255 0.009 ENST00000421589.1
 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_+_49518113 0.008 ENST00000529246.2
 C6orf141
chromosome 6 open reading frame 141
chr13_-_34250861 0.008 ENST00000445227.1
ENST00000454681.2
 RP11-141M1.3

RP11-141M1.3

chr14_+_32030582 0.007 ENST00000550649.1
ENST00000281081.7
 NUBPL

nucleotide binding protein-like

chr17_-_64225508 0.006 ENST00000205948.6
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_-_47983519 0.006 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr1_+_40506392 0.006 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
 CAP1











CAP, adenylate cyclase-associated protein 1 (yeast)











chr5_-_140998616 0.006 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
 DIAPH1





diaphanous-related formin 1





chr17_-_79623597 0.006 ENST00000574024.1
ENST00000331056.5
 PDE6G

phosphodiesterase 6G, cGMP-specific, rod, gamma

chr14_+_97925151 0.006 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
 CTD-2506J14.1


CTD-2506J14.1


chr15_+_45544426 0.004 ENST00000347644.3
ENST00000560438.1
 SLC28A2

solute carrier family 28 (concentrative nucleoside transporter), member 2

chr17_-_33390667 0.004 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
 RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr1_+_193028552 0.002 ENST00000400968.2
ENST00000432079.1
 TROVE2

TROVE domain family, member 2

chr8_+_50824233 0.001 ENST00000522124.1
 SNTG1
syntrophin, gamma 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters