Motif ID: POU2F2_POU3F1

Z-value: 1.393

Transcription factors associated with POU2F2_POU3F1:

Gene SymbolEntrez IDGene Name
POU2F2 ENSG00000028277.16 POU2F2
POU3F1 ENSG00000185668.5 POU3F1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636543_42636607-0.186.5e-01Click!
POU3F1hg19_v2_chr1_-_38512450_38512474-0.117.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_17516449 4.072 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr8_+_19796381 3.452 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr17_-_19651668 3.340 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr3_+_98250743 3.321 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr6_+_26124373 2.737 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr6_-_26124138 2.514 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr2_-_207082624 2.399 ENST00000458440.1
ENST00000437420.1
GPR1

G protein-coupled receptor 1

chr2_-_207082748 2.059 ENST00000407325.2
ENST00000411719.1
GPR1

G protein-coupled receptor 1

chr17_-_19651654 2.032 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr11_+_34642656 1.982 ENST00000257831.3
ENST00000450654.2
EHF

ets homologous factor

chr5_-_88120151 1.816 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr6_-_27100529 1.719 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr6_-_27782548 1.627 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr6_-_26043885 1.626 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr14_-_34420259 1.548 ENST00000250457.3
ENST00000547327.2
EGLN3

egl-9 family hypoxia-inducible factor 3

chr6_-_26033796 1.534 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr17_-_19651598 1.532 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr8_+_26435359 1.457 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr6_+_26183958 1.453 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr5_+_159895275 1.449 ENST00000517927.1
MIR146A
microRNA 146a
chr2_-_145278475 1.360 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_36608422 1.331 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_27861190 1.331 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr6_+_27114861 1.305 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr7_-_142511084 1.254 ENST00000417977.2
TRBV30
T cell receptor beta variable 30 (gene/pseudogene)
chr17_+_72426891 1.252 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr7_-_50860565 1.222 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr1_-_149814478 1.161 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr4_-_25865159 1.143 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr1_+_149822620 1.140 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr5_-_88120083 1.137 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr6_-_27114577 1.134 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr6_-_27860956 1.132 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr7_+_129932974 1.123 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr10_+_24528108 1.096 ENST00000438429.1
KIAA1217
KIAA1217
chr1_-_23886285 1.067 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_-_149858227 1.049 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr19_+_17516624 1.028 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9


CTD-2521M24.9


chr1_+_201979645 1.020 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr1_+_149858461 1.003 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr12_-_10978957 0.991 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_+_201979743 0.966 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_+_33292507 0.907 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr1_+_81771806 0.888 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr1_+_170632250 0.856 ENST00000367760.3
PRRX1
paired related homeobox 1
chr6_+_31588478 0.847 ENST00000376007.4
ENST00000376033.2
PRRC2A

proline-rich coiled-coil 2A

chrX_-_43832711 0.842 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chrX_-_48776292 0.769 ENST00000376509.4
PIM2
pim-2 oncogene
chr11_-_94964210 0.730 ENST00000416495.2
ENST00000393234.1
SESN3

sestrin 3

chr6_+_26158343 0.718 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr1_-_196577489 0.690 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
KCNT2



potassium channel, subfamily T, member 2



chr7_+_97840739 0.686 ENST00000609256.1
BHLHA15
basic helix-loop-helix family, member a15
chr4_-_40517984 0.674 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr6_-_10415470 0.662 ENST00000379604.2
ENST00000379613.3
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr6_+_27775899 0.661 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr1_-_173020056 0.643 ENST00000239468.2
ENST00000404377.3
TNFSF18

tumor necrosis factor (ligand) superfamily, member 18

chr6_+_10585979 0.606 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_+_51317788 0.605 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr8_-_25315905 0.601 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr11_-_94964354 0.593 ENST00000536441.1
SESN3
sestrin 3
chr5_+_140593509 0.592 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr17_+_63133587 0.584 ENST00000449996.3
ENST00000262406.9
RGS9

regulator of G-protein signaling 9

chr17_+_63133526 0.584 ENST00000443584.3
RGS9
regulator of G-protein signaling 9
chr6_-_82462425 0.570 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr14_-_23446021 0.549 ENST00000553592.1
AJUBA
ajuba LIM protein
chr21_-_28215332 0.548 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_+_12695702 0.546 ENST00000381136.2
TYRP1
tyrosinase-related protein 1
chr5_-_141030943 0.531 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1


FCH and double SH3 domains 1


chr2_-_211036051 0.530 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chr8_-_72274467 0.530 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr3_-_178969403 0.529 ENST00000314235.5
ENST00000392685.2
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr3_+_187957646 0.519 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_+_124320665 0.514 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr7_+_16793160 0.511 ENST00000262067.4
TSPAN13
tetraspanin 13
chr16_-_19897455 0.504 ENST00000568214.1
ENST00000569479.1
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr14_-_23446003 0.500 ENST00000553911.1
AJUBA
ajuba LIM protein
chr6_-_10415218 0.467 ENST00000466073.1
ENST00000498450.1
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr1_+_225600404 0.460 ENST00000366845.2
AC092811.1
AC092811.1
chr18_-_74839891 0.454 ENST00000581878.1
MBP
myelin basic protein
chr5_+_145317356 0.449 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr12_-_11287243 0.443 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr12_+_113344582 0.440 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr6_+_27782788 0.436 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr8_-_16859690 0.436 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr12_-_7245125 0.435 ENST00000542285.1
ENST00000540610.1
C1R

complement component 1, r subcomponent

chr1_-_149783914 0.428 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF


histone cluster 2, H2bf


chr3_-_24207039 0.428 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chrX_-_55020511 0.426 ENST00000375006.3
ENST00000374992.2
PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

chr12_-_11139511 0.420 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr19_-_50143452 0.418 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr8_+_25316489 0.415 ENST00000330560.3
CDCA2
cell division cycle associated 2
chr12_-_11175219 0.414 ENST00000390673.2
TAS2R19
taste receptor, type 2, member 19
chr12_-_7245018 0.412 ENST00000543835.1
ENST00000535233.2
C1R

complement component 1, r subcomponent

chr8_-_33370607 0.411 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr12_-_7245152 0.407 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr3_+_50192833 0.393 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr12_-_66275350 0.392 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chr16_+_23847355 0.384 ENST00000498058.1
PRKCB
protein kinase C, beta
chr9_+_92219919 0.384 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr5_+_101569696 0.382 ENST00000597120.1
AC008948.1
AC008948.1
chr8_+_25316707 0.378 ENST00000380665.3
CDCA2
cell division cycle associated 2
chr17_-_48072574 0.377 ENST00000434704.2
DLX3
distal-less homeobox 3
chr1_+_182584314 0.376 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr12_-_7245080 0.370 ENST00000541042.1
ENST00000540242.1
C1R

complement component 1, r subcomponent

chr7_-_14029283 0.366 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr19_+_17858509 0.359 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1


FCH domain only 1


chr6_+_37137939 0.357 ENST00000373509.5
PIM1
pim-1 oncogene
chr7_-_14028488 0.356 ENST00000405358.4
ETV1
ets variant 1
chr8_-_72274355 0.354 ENST00000388741.2
EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_113344811 0.354 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr17_+_63096903 0.349 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr2_+_166430619 0.349 ENST00000409420.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr11_-_34379546 0.348 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr17_+_62461569 0.344 ENST00000603557.1
ENST00000605096.1
MILR1

mast cell immunoglobulin-like receptor 1

chr3_+_69928256 0.344 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr8_-_72274095 0.340 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr16_+_23847339 0.332 ENST00000303531.7
PRKCB
protein kinase C, beta
chr3_+_50192457 0.329 ENST00000414301.1
ENST00000450338.1
SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

chr4_+_87857538 0.324 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr16_+_19429018 0.322 ENST00000542583.2
TMC5
transmembrane channel-like 5
chr2_+_220143989 0.318 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr19_-_40931891 0.318 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr8_+_92261516 0.318 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr3_-_46068969 0.316 ENST00000542109.1
ENST00000395946.2
XCR1

chemokine (C motif) receptor 1

chr12_+_49297899 0.315 ENST00000552942.1
ENST00000320516.4
CCDC65

coiled-coil domain containing 65

chr18_+_32290218 0.314 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr19_+_29493456 0.312 ENST00000591143.1
ENST00000592653.1
CTD-2081K17.2

CTD-2081K17.2

chr12_-_95941987 0.305 ENST00000537435.2
USP44
ubiquitin specific peptidase 44
chr5_-_66492562 0.302 ENST00000256447.4
CD180
CD180 molecule
chrX_+_12993336 0.292 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr16_+_53164956 0.291 ENST00000563410.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_-_6614565 0.291 ENST00000377705.5
NOL9
nucleolar protein 9
chr6_+_26251835 0.290 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chrX_-_19504642 0.285 ENST00000469203.2
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr7_-_73038822 0.284 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL


MLX interacting protein-like


chrX_+_12993202 0.273 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chr3_+_50192499 0.272 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr12_-_11214893 0.268 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr1_+_206730484 0.265 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr6_+_27100811 0.264 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr1_-_10532531 0.263 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr2_+_202047596 0.263 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr8_+_30496078 0.262 ENST00000517349.1
SMIM18
small integral membrane protein 18
chr12_+_41221794 0.257 ENST00000547849.1
CNTN1
contactin 1
chr7_-_73038867 0.256 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL



MLX interacting protein-like



chr4_-_156297919 0.250 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr17_+_46133307 0.246 ENST00000580037.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr4_-_18023350 0.245 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
LCORL


ligand dependent nuclear receptor corepressor-like


chr2_-_214013353 0.244 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2



IKAROS family zinc finger 2 (Helios)



chr6_-_27775694 0.240 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr9_-_98189055 0.239 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr10_-_14574705 0.239 ENST00000489100.1
FAM107B
family with sequence similarity 107, member B
chr19_+_56111680 0.238 ENST00000301073.3
ZNF524
zinc finger protein 524
chr16_+_56691606 0.234 ENST00000334350.6
MT1F
metallothionein 1F
chr2_+_220144052 0.234 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2


DnaJ (Hsp40) homolog, subfamily B, member 2


chr3_+_50192537 0.231 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr10_+_105314881 0.229 ENST00000437579.1
NEURL
neuralized E3 ubiquitin protein ligase 1
chr8_-_42396185 0.227 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr5_+_158527485 0.225 ENST00000517335.1
RP11-175K6.1
RP11-175K6.1
chr2_-_61108449 0.223 ENST00000439412.1
ENST00000452343.1
AC010733.4

AC010733.4

chr6_+_34204642 0.221 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr17_+_73521763 0.218 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)




chr19_+_35820064 0.217 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22











CD22 molecule











chr10_+_71211212 0.211 ENST00000373290.2
TSPAN15
tetraspanin 15
chr17_+_38497640 0.209 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr11_-_27494309 0.208 ENST00000389858.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr8_-_42358742 0.208 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_11150474 0.206 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr12_-_11091862 0.200 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr1_-_6052463 0.198 ENST00000378156.4
NPHP4
nephronophthisis 4
chr7_-_100183742 0.196 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr11_-_27494279 0.193 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr9_+_35658377 0.193 ENST00000378409.3
CCDC107
coiled-coil domain containing 107
chr2_+_183582774 0.191 ENST00000537515.1
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr4_-_44728530 0.190 ENST00000507534.1
GNPDA2
glucosamine-6-phosphate deaminase 2
chr12_+_7053228 0.176 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr16_-_75285762 0.176 ENST00000564028.1
BCAR1
breast cancer anti-estrogen resistance 1
chr1_-_94586651 0.175 ENST00000535735.1
ENST00000370225.3
ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr1_+_156052354 0.175 ENST00000368301.2
LMNA
lamin A/C
chr5_-_87564620 0.175 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B




transmembrane protein 161B




chr4_-_83931862 0.170 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54



lin-54 homolog (C. elegans)



chr10_-_129691195 0.167 ENST00000368671.3
CLRN3
clarin 3
chr7_-_102789629 0.165 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
NAPEPLD


N-acyl phosphatidylethanolamine phospholipase D


chr12_-_16760021 0.165 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_+_125758865 0.164 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr22_-_24096630 0.163 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr4_-_40516560 0.161 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr1_-_117021430 0.160 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4


RP4-655J12.4


chr12_+_7053172 0.158 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr2_+_54785485 0.158 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_+_125758813 0.157 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr15_+_45406519 0.156 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr22_-_24096562 0.155 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr16_-_20566616 0.155 ENST00000569163.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr1_+_104198377 0.155 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr4_-_99578776 0.153 ENST00000515287.1
TSPAN5
tetraspanin 5
chr15_-_41166414 0.152 ENST00000220507.4
RHOV
ras homolog family member V
chr2_+_145780662 0.151 ENST00000423031.1
TEX41
testis expressed 41 (non-protein coding)
chr4_-_44728559 0.150 ENST00000509756.1
ENST00000507917.1
ENST00000295448.3
GNPDA2


glucosamine-6-phosphate deaminase 2


chr4_+_40194609 0.149 ENST00000508513.1
RHOH
ras homolog family member H

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.5 3.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890) chylomicron remodeling(GO:0034371)
0.4 6.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 3.0 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.1 GO:0003409 optic cup structural organization(GO:0003409)
0.2 0.8 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.2 0.5 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 1.4 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.5 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.5 GO:0060940 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 2.0 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.3 GO:0006043 glucosamine catabolic process(GO:0006043)
0.1 0.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.6 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.5 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.4 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.5 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.3 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 1.2 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 2.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.1 1.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 9.8 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.1 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.5 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.4 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 3.3 GO:0072678 T cell migration(GO:0072678)
0.1 6.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 4.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.4 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.9 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.3 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.1 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 4.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:1900211 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.4 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 1.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.0 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.0 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.0 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.1 GO:0000786 nucleosome(GO:0000786)
0.2 3.5 GO:0042627 chylomicron(GO:0042627)
0.1 1.3 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 4.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0017129 triglyceride binding(GO:0017129)
0.8 7.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.8 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 4.5 GO:0042923 neuropeptide binding(GO:0042923)
0.2 0.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 2.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 3.2 GO:0003680 AT DNA binding(GO:0003680)
0.2 4.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 12.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.0 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 2.6 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.7 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 20.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 3.5 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.2 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 2.9 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.7 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.5 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate