Motif ID: PITX3

Z-value: 0.917


Transcription factors associated with PITX3:

Gene SymbolEntrez IDGene Name
PITX3 ENSG00000107859.5 PITX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PITX3hg19_v2_chr10_-_104001231_1040012740.909.8e-04Click!


Activity profile for motif PITX3.

activity profile for motif PITX3


Sorted Z-values histogram for motif PITX3

Sorted Z-values for motif PITX3



Network of associatons between targets according to the STRING database.



First level regulatory network of PITX3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_207262578 2.334 ENST00000243611.5
ENST00000367076.3
C4BPB

complement component 4 binding protein, beta

chr12_-_10022735 1.853 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr12_+_52668394 1.604 ENST00000423955.2
KRT86
keratin 86
chr17_-_19648916 1.464 ENST00000444455.1
ENST00000439102.2
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr1_+_207262627 1.405 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr1_+_207262170 1.386 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr5_-_149792295 1.267 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr11_+_34654011 1.250 ENST00000531794.1
EHF
ets homologous factor
chr6_+_33043703 1.194 ENST00000418931.2
ENST00000535465.1
HLA-DPB1

major histocompatibility complex, class II, DP beta 1

chr7_+_117864708 1.179 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ANKRD7



ankyrin repeat domain 7



chr19_-_17516449 1.176 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr9_-_90589586 1.176 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr6_+_116782527 1.163 ENST00000368606.3
ENST00000368605.1
FAM26F

family with sequence similarity 26, member F

chr1_+_120254510 1.160 ENST00000369409.4
PHGDH
phosphoglycerate dehydrogenase
chr3_+_98250743 1.144 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr8_-_125577940 1.126 ENST00000519168.1
ENST00000395508.2
MTSS1

metastasis suppressor 1

chrX_-_102565858 1.066 ENST00000449185.1
ENST00000536889.1
BEX2

brain expressed X-linked 2

chr4_+_154622652 1.048 ENST00000260010.6
TLR2
toll-like receptor 2
chr4_+_169013666 1.040 ENST00000359299.3
ANXA10
annexin A10
chr1_+_207262540 1.035 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr18_+_61564389 1.021 ENST00000397996.2
ENST00000418725.1
SERPINB10

serpin peptidase inhibitor, clade B (ovalbumin), member 10

chr9_-_90589402 1.015 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chr9_+_470288 0.975 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr17_-_19648683 0.943 ENST00000573368.1
ENST00000457500.2
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr6_-_32908792 0.940 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chrX_-_102565932 0.917 ENST00000372674.1
ENST00000372677.3
BEX2

brain expressed X-linked 2

chr1_+_207070775 0.898 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24


interleukin 24


chr1_+_169079823 0.885 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_81771806 0.881 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr2_+_33661382 0.866 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_+_155250824 0.783 ENST00000297375.4
EN2
engrailed homeobox 2
chr10_-_61122220 0.780 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C






family with sequence similarity 13, member C






chr11_+_62104897 0.769 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1


asparaginase like 1


chr19_+_50979753 0.768 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
EMC10



ER membrane protein complex subunit 10



chr11_+_63304273 0.760 ENST00000439013.2
ENST00000255688.3
RARRES3

retinoic acid receptor responder (tazarotene induced) 3

chr3_+_173116225 0.759 ENST00000457714.1
NLGN1
neuroligin 1
chr7_-_150038704 0.754 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2



retinoic acid receptor responder (tazarotene induced) 2



chr2_-_136873735 0.751 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr3_-_169487617 0.742 ENST00000330368.2
ACTRT3
actin-related protein T3
chr2_+_33683109 0.695 ENST00000437184.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_169530574 0.683 ENST00000316515.7
ENST00000522830.1
ENST00000522526.2
LRRC34


leucine rich repeat containing 34


chr1_-_11107280 0.678 ENST00000400897.3
ENST00000400898.3
MASP2

mannan-binding lectin serine peptidase 2

chr7_+_117864815 0.670 ENST00000433239.1
ANKRD7
ankyrin repeat domain 7
chr7_+_142498725 0.666 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr5_+_140593509 0.635 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr2_+_37571717 0.633 ENST00000338415.3
ENST00000404976.1
QPCT

glutaminyl-peptide cyclotransferase

chr3_-_182881595 0.621 ENST00000476015.1
LAMP3
lysosomal-associated membrane protein 3
chr3_-_178969403 0.620 ENST00000314235.5
ENST00000392685.2
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr1_-_39407467 0.615 ENST00000540558.1
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr1_+_28261533 0.608 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr10_+_5005598 0.608 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr10_-_5046042 0.602 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr10_-_61495760 0.593 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr8_-_110656995 0.592 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr9_+_12693336 0.591 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr2_-_222437049 0.583 ENST00000541600.1
EPHA4
EPH receptor A4
chr5_+_76114758 0.580 ENST00000514165.1
ENST00000296677.4
F2RL1

coagulation factor II (thrombin) receptor-like 1

chr13_-_62001982 0.568 ENST00000409186.1
PCDH20
protocadherin 20
chr10_+_103986085 0.559 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr1_-_159046617 0.558 ENST00000368130.4
AIM2
absent in melanoma 2
chr16_+_58010339 0.558 ENST00000290871.5
ENST00000441824.2
TEPP

testis, prostate and placenta expressed

chr14_-_54418598 0.557 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr10_+_124320156 0.555 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1





deleted in malignant brain tumors 1





chrX_+_38420623 0.552 ENST00000378482.2
TSPAN7
tetraspanin 7
chr6_+_147830362 0.551 ENST00000566741.1
SAMD5
sterile alpha motif domain containing 5
chr4_-_74847800 0.551 ENST00000296029.3
PF4
platelet factor 4
chr20_+_12989822 0.546 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr12_-_66317967 0.546 ENST00000601398.1
AC090673.2
Uncharacterized protein
chr18_+_52385068 0.544 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr8_-_72268721 0.544 ENST00000419131.1
ENST00000388743.2
EYA1

eyes absent homolog 1 (Drosophila)

chr6_+_121756809 0.543 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr5_-_146781153 0.542 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr1_-_1297157 0.540 ENST00000477278.2
MXRA8
matrix-remodelling associated 8
chr8_-_27462822 0.538 ENST00000522098.1
CLU
clusterin
chr1_+_82266053 0.537 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr1_+_207262881 0.536 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr3_-_172241250 0.534 ENST00000420541.2
ENST00000241261.2
TNFSF10

tumor necrosis factor (ligand) superfamily, member 10

chr5_+_133451254 0.534 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7







transcription factor 7 (T-cell specific, HMG-box)







chr8_+_19536083 0.529 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr12_-_13248562 0.527 ENST00000457134.2
ENST00000537302.1
GSG1

germ cell associated 1

chr9_-_39288092 0.525 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3



contactin associated protein-like 3



chr4_+_126237554 0.517 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr22_-_36018569 0.509 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr12_+_16500037 0.507 ENST00000536371.1
ENST00000010404.2
MGST1

microsomal glutathione S-transferase 1

chr2_+_65215604 0.504 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr10_+_5135981 0.500 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr5_+_133562095 0.499 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr1_-_47655686 0.499 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr7_+_94536898 0.497 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr1_+_31883048 0.496 ENST00000536859.1
SERINC2
serine incorporator 2
chr5_+_140579162 0.484 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr6_+_147981838 0.482 ENST00000427015.1
ENST00000432506.1
RP11-307P5.1

RP11-307P5.1

chrX_+_38420783 0.482 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7


tetraspanin 7


chr12_-_13248732 0.481 ENST00000396302.3
GSG1
germ cell associated 1
chrX_-_27999566 0.480 ENST00000441525.1
DCAF8L1
DDB1 and CUL4 associated factor 8-like 1
chr11_-_36619771 0.477 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr18_+_61557781 0.474 ENST00000443281.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr1_+_28261492 0.469 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_+_5710919 0.466 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr5_+_95066823 0.465 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr6_-_33048503 0.460 ENST00000453337.1
ENST00000417724.1
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

chr2_+_158114051 0.454 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr20_+_12989895 0.446 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr9_+_113431059 0.437 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr11_-_110561721 0.436 ENST00000357139.3
ARHGAP20
Rho GTPase activating protein 20
chr3_-_171489085 0.434 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr12_-_13248705 0.431 ENST00000396310.2
GSG1
germ cell associated 1
chr1_+_28261621 0.427 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr3_+_182511266 0.426 ENST00000323116.5
ENST00000493826.1
ATP11B

ATPase, class VI, type 11B

chr6_-_26032288 0.425 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr4_-_109541610 0.425 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr4_-_75719896 0.424 ENST00000395743.3
BTC
betacellulin
chr12_+_104682496 0.421 ENST00000378070.4
TXNRD1
thioredoxin reductase 1
chr20_+_12989596 0.420 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr7_+_73242069 0.420 ENST00000435050.1
CLDN4
claudin 4
chr8_+_19796381 0.418 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr19_+_58180303 0.418 ENST00000318203.5
ZSCAN4
zinc finger and SCAN domain containing 4
chr18_+_32290218 0.417 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr1_-_21606013 0.415 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr4_-_52883786 0.408 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr12_+_104682667 0.405 ENST00000527335.1
TXNRD1
thioredoxin reductase 1
chr5_-_38595498 0.405 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr4_-_89080003 0.404 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr15_+_59903975 0.403 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr17_+_18625336 0.401 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L




tripartite motif containing 16-like




chr10_-_61122934 0.398 ENST00000512919.1
FAM13C
family with sequence similarity 13, member C
chr1_+_60280458 0.397 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr8_-_42360015 0.394 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr8_+_8559406 0.394 ENST00000519106.1
CLDN23
claudin 23
chr6_-_33037019 0.393 ENST00000437811.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr6_+_122793058 0.392 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr10_+_91092241 0.392 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr1_-_31902614 0.387 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr10_+_88780049 0.386 ENST00000343959.4
FAM25A
family with sequence similarity 25, member A
chr1_-_36789755 0.385 ENST00000270824.1
EVA1B
eva-1 homolog B (C. elegans)
chr3_+_173302222 0.385 ENST00000361589.4
NLGN1
neuroligin 1
chr8_-_72268968 0.384 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_113416340 0.384 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr17_-_65992544 0.383 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr15_+_59908633 0.381 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_-_170626418 0.380 ENST00000474096.1
ENST00000295822.2
EIF5A2

eukaryotic translation initiation factor 5A2

chr8_-_72268889 0.378 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr19_-_44388116 0.378 ENST00000587539.1
ZNF404
zinc finger protein 404
chr1_-_232651312 0.378 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_-_89079817 0.377 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr10_+_6821545 0.376 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr8_-_28347737 0.376 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16



F-box protein 16



chr8_-_150563 0.371 ENST00000523795.2
RP11-585F1.10
Protein LOC100286914
chr4_+_39640787 0.369 ENST00000532680.1
RP11-539G18.2
RP11-539G18.2
chr8_+_61822605 0.366 ENST00000526936.1
AC022182.1
AC022182.1
chr11_-_1771797 0.366 ENST00000340134.4
IFITM10
interferon induced transmembrane protein 10
chr1_-_204436344 0.366 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr16_+_19429018 0.365 ENST00000542583.2
TMC5
transmembrane channel-like 5
chr10_-_61122625 0.359 ENST00000468840.2
FAM13C
family with sequence similarity 13, member C
chr15_-_52587945 0.359 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chrX_+_96138907 0.357 ENST00000373040.3
RPA4
replication protein A4, 30kDa
chr12_+_113416191 0.356 ENST00000342315.4
ENST00000392583.2
OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

chr11_+_62623544 0.356 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2


solute carrier family 3 (amino acid transporter heavy chain), member 2


chr1_-_39395165 0.354 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr3_+_173113898 0.353 ENST00000423427.1
NLGN1
neuroligin 1
chr11_+_62623621 0.353 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr6_-_27114577 0.352 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr11_+_71903169 0.352 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr16_-_68269971 0.351 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr3_-_170626376 0.350 ENST00000487522.1
ENST00000474417.1
EIF5A2

eukaryotic translation initiation factor 5A2

chr4_+_86525299 0.348 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr2_-_222436988 0.346 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4



EPH receptor A4



chrX_-_15683147 0.342 ENST00000380342.3
TMEM27
transmembrane protein 27
chr12_-_45269251 0.341 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr2_+_120770581 0.339 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr6_+_111580508 0.338 ENST00000368847.4
KIAA1919
KIAA1919
chr16_+_4421841 0.337 ENST00000304735.3
VASN
vasorin
chr4_+_75480629 0.337 ENST00000380846.3
AREGB
amphiregulin B
chr1_+_104159999 0.336 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr8_-_110660975 0.335 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr8_-_27457494 0.335 ENST00000521770.1
CLU
clusterin
chr8_+_26435915 0.333 ENST00000523027.1
DPYSL2
dihydropyrimidinase-like 2
chr9_+_116343192 0.331 ENST00000471324.2
RGS3
regulator of G-protein signaling 3
chr10_+_91087651 0.330 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr7_+_141490017 0.330 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr7_-_107643567 0.329 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1


laminin, beta 1


chr9_+_130911723 0.329 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr6_+_69345166 0.327 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr4_+_126315091 0.326 ENST00000335110.5
FAT4
FAT atypical cadherin 4
chr3_-_180397256 0.324 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr2_-_100925967 0.322 ENST00000409647.1
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr19_-_58446721 0.322 ENST00000396147.1
ENST00000595569.1
ENST00000599852.1
ENST00000425570.3
ENST00000601593.1
ZNF418




zinc finger protein 418




chr3_+_179065474 0.321 ENST00000471841.1
ENST00000280653.7
MFN1

mitofusin 1

chr17_-_4643161 0.321 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr3_+_184032283 0.318 ENST00000346169.2
ENST00000414031.1
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr5_+_140753444 0.317 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr11_+_5711010 0.317 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr17_+_41476327 0.316 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr3_-_186262166 0.313 ENST00000307944.5
CRYGS
crystallin, gamma S
chr19_+_37742773 0.312 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5


AC012309.5


chr8_-_81787006 0.311 ENST00000327835.3
ZNF704
zinc finger protein 704
chr6_+_26124373 0.311 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr3_-_172312460 0.311 ENST00000418839.2
RP11-408H1.3
RP11-408H1.3
chr12_-_13248598 0.310 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr4_-_89080362 0.310 ENST00000503830.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.6 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.4 1.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.4 1.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.4 1.5 GO:0098942 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.3 1.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 0.9 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.3 0.8 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.3 1.1 GO:0006566 threonine metabolic process(GO:0006566)
0.3 1.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.3 1.3 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3 0.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.2 0.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 1.7 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 0.6 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 0.6 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.7 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 0.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 1.1 GO:0030035 microspike assembly(GO:0030035)
0.1 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.5 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.8 GO:0048389 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 0.7 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.9 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.9 GO:0060356 leucine import(GO:0060356)
0.1 1.5 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 1.0 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.9 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 1.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.4 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.4 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.4 GO:0018277 protein deamination(GO:0018277)
0.1 0.3 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.3 GO:0071812 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 1.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.9 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0002586 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.4 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.3 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.8 GO:0015825 L-serine transport(GO:0015825)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.7 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.9 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.9 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.2 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.2 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.5 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 1.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.4 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.0 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0045862 positive regulation of proteolysis(GO:0045862)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.5 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 1.9 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.2 GO:2000809 positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:1904796 regulation of core promoter binding(GO:1904796)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 4.5 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.1 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.4 GO:0072678 T cell migration(GO:0072678)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.5 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.4 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0042268 regulation of cytolysis(GO:0042268) positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.5 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.2 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.6 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.0 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0003266 regulation of secondary heart field cardioblast proliferation(GO:0003266)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.0 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.6 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 1.7 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.0 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:1901297 regulation of Wnt signaling pathway involved in heart development(GO:0003307) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0046851 negative regulation of bone remodeling(GO:0046851)
0.0 0.0 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.4 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.0 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.0 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.0 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.0 GO:1903527 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.0 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0001738 establishment of planar polarity(GO:0001736) morphogenesis of a polarized epithelium(GO:0001738) establishment of tissue polarity(GO:0007164)
0.0 0.0 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.0 0.0 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.0 GO:0010889 regulation of sequestering of triglyceride(GO:0010889)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0015819 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:0006882 cellular zinc ion homeostasis(GO:0006882)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 4.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.6 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0043257 laminin-8 complex(GO:0043257)
0.1 0.9 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.3 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.3 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.6 GO:0032433 filopodium tip(GO:0032433)
0.1 1.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 5.6 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0005921 gap junction(GO:0005921)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.9 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.0 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 2.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 0.8 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 1.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2 1.7 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 0.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 0.6 GO:0001855 complement component C4b binding(GO:0001855)
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 1.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 1.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 0.4 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 1.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 1.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:1990175 EH domain binding(GO:1990175)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.4 GO:0042835 BRE binding(GO:0042835)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.8 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.0 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.3 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.0 GO:0005168 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.5 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 1.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.1 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.5 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.3 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 3.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.0 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.1 2.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.9 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 0.8 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.1 0.8 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 1.1 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME_S_PHASE Genes involved in S Phase
0.0 1.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters