Motif ID: PITX1

Z-value: 2.128


Transcription factors associated with PITX1:

Gene SymbolEntrez IDGene Name
PITX1 ENSG00000069011.11 PITX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PITX1hg19_v2_chr5_-_134369973_134369988-0.908.7e-04Click!


Activity profile for motif PITX1.

activity profile for motif PITX1


Sorted Z-values histogram for motif PITX1

Sorted Z-values for motif PITX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PITX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_114252193 6.108 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chr17_+_39975455 5.356 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr22_+_42095497 3.501 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1



meiosis inhibitor 1



chr17_-_76628125 3.235 ENST00000586185.1
ENST00000591384.1
CTD-2357A8.3

CTD-2357A8.3

chr17_+_39975544 2.969 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr4_-_70653673 2.903 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr1_+_43766642 2.802 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr19_-_39826639 2.559 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr1_+_43766668 2.544 ENST00000441333.2
ENST00000538015.1
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr4_+_183164574 2.494 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr15_-_74658493 2.477 ENST00000419019.2
ENST00000569662.1
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr3_+_111717511 2.378 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr22_-_33968239 2.363 ENST00000452586.2
ENST00000421768.1
LARGE

like-glycosyltransferase

chr19_-_54567159 2.219 ENST00000338372.2
ENST00000376626.1
VSTM1

V-set and transmembrane domain containing 1

chr4_+_37003420 2.161 ENST00000562049.1
RP11-103J17.2
RP11-103J17.2
chr15_-_74658519 2.100 ENST00000450547.1
ENST00000358632.4
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr17_+_812872 2.072 ENST00000576252.1
RP11-676J12.7
Uncharacterized protein
chr9_+_82267508 1.962 ENST00000490347.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_-_10687948 1.947 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr2_+_128293323 1.917 ENST00000389524.4
ENST00000428314.1
MYO7B

myosin VIIB

chr3_+_46921732 1.831 ENST00000418619.1
PTH1R
parathyroid hormone 1 receptor
chr1_-_150738261 1.829 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr22_+_18721427 1.820 ENST00000342888.3
AC008132.1
Uncharacterized protein
chr1_-_159869912 1.816 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr17_+_44039704 1.793 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
MAPT




microtubule-associated protein tau




chr19_+_11658655 1.734 ENST00000588935.1
CNN1
calponin 1, basic, smooth muscle
chr11_+_33037401 1.691 ENST00000241051.3
DEPDC7
DEP domain containing 7
chr19_+_41281060 1.653 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr1_+_151030234 1.621 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr6_+_151662815 1.590 ENST00000359755.5
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_114211474 1.584 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1

RP11-438N16.1

chr16_-_30064244 1.548 ENST00000571269.1
ENST00000561666.1
FAM57B

family with sequence similarity 57, member B

chr22_-_21581926 1.546 ENST00000401924.1
GGT2
gamma-glutamyltransferase 2
chr1_-_213020991 1.515 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chr19_-_6433765 1.501 ENST00000321510.6
SLC25A41
solute carrier family 25, member 41
chr20_+_55099542 1.500 ENST00000371328.3
FAM209A
family with sequence similarity 209, member A
chr19_-_10687983 1.487 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr12_+_54892550 1.480 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr1_-_161207875 1.478 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
















nuclear receptor subfamily 1, group I, member 3
















chr13_+_43597269 1.474 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr20_+_50827175 1.467 ENST00000454600.1
RP4-723E3.1
RP4-723E3.1
chr19_+_42817450 1.439 ENST00000301204.3
TMEM145
transmembrane protein 145
chr19_-_10687907 1.438 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr14_-_75079294 1.373 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr13_+_107028897 1.370 ENST00000439790.1
ENST00000435024.1
LINC00460

long intergenic non-protein coding RNA 460

chr1_+_247582097 1.355 ENST00000391827.2
NLRP3
NLR family, pyrin domain containing 3
chr19_-_48613820 1.350 ENST00000596352.1
PLA2G4C
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr2_-_70352421 1.334 ENST00000414141.1
AC016700.5
AC016700.5
chr22_+_20692438 1.325 ENST00000434783.3
FAM230A
family with sequence similarity 230, member A
chr4_-_189030422 1.319 ENST00000536972.1
TRIML2
tripartite motif family-like 2
chr1_-_156786634 1.318 ENST00000392306.2
ENST00000368199.3
SH2D2A

SH2 domain containing 2A

chr17_-_38821373 1.315 ENST00000394052.3
KRT222
keratin 222
chr9_+_72435709 1.308 ENST00000377197.3
ENST00000527647.1
C9orf135

chromosome 9 open reading frame 135

chr19_-_6690723 1.293 ENST00000601008.1
C3
complement component 3
chr1_-_156786530 1.290 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr12_+_121647868 1.287 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
P2RX4



purinergic receptor P2X, ligand-gated ion channel, 4



chr13_+_50070077 1.286 ENST00000378319.3
ENST00000426879.1
PHF11

PHD finger protein 11

chr15_+_65903680 1.255 ENST00000537259.1
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr16_+_66637777 1.231 ENST00000563672.1
ENST00000424011.2
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr15_-_83837983 1.231 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chrX_+_55246771 1.227 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chr11_-_65641044 1.226 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr21_+_47518695 1.209 ENST00000436769.1
COL6A2
collagen, type VI, alpha 2
chr2_-_62115725 1.207 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
CCT4


chaperonin containing TCP1, subunit 4 (delta)


chr10_+_126150369 1.192 ENST00000392757.4
ENST00000368842.5
ENST00000368839.1
LHPP


phospholysine phosphohistidine inorganic pyrophosphate phosphatase


chr15_-_78913628 1.176 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr16_+_30194118 1.174 ENST00000563778.1
CORO1A
coronin, actin binding protein, 1A
chr9_+_131464767 1.157 ENST00000291906.4
PKN3
protein kinase N3
chr16_-_11922665 1.157 ENST00000573319.1
ENST00000577041.1
ENST00000574028.1
ENST00000571259.1
ENST00000573037.1
ENST00000571158.1
BCAR4





breast cancer anti-estrogen resistance 4 (non-protein coding)





chr19_+_36027660 1.121 ENST00000585510.1
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_-_54567035 1.108 ENST00000366170.2
ENST00000425006.2
VSTM1

V-set and transmembrane domain containing 1

chr21_+_35736302 1.099 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr3_-_51937331 1.084 ENST00000310914.5
IQCF1
IQ motif containing F1
chr22_+_42148515 1.082 ENST00000540880.1
MEI1
meiosis inhibitor 1
chr12_-_132690573 1.058 ENST00000397325.2
ENST00000538356.1
GALNT9

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)

chr11_-_65314905 1.057 ENST00000527339.1
LTBP3
latent transforming growth factor beta binding protein 3
chr5_+_166711804 1.048 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr17_-_47045949 1.028 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chrX_+_16668278 1.023 ENST00000380200.3
S100G
S100 calcium binding protein G
chr14_+_100531615 1.016 ENST00000392920.3
EVL
Enah/Vasp-like
chr19_-_7553889 1.010 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr20_+_55108302 0.999 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr17_+_4337199 0.979 ENST00000333476.2
SPNS3
spinster homolog 3 (Drosophila)
chr12_+_57146233 0.977 ENST00000554643.1
ENST00000556650.1
ENST00000554150.1
ENST00000554155.1
HSD17B6



hydroxysteroid (17-beta) dehydrogenase 6



chr6_+_127898312 0.969 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr22_-_37976082 0.959 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chr2_+_132285406 0.957 ENST00000295171.6
ENST00000409856.3
CCDC74A

coiled-coil domain containing 74A

chr3_+_38029462 0.956 ENST00000283713.6
VILL
villin-like
chr12_+_121647962 0.945 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr16_-_30023615 0.945 ENST00000564979.1
ENST00000563378.1
DOC2A

double C2-like domains, alpha

chr5_+_159614374 0.941 ENST00000393980.4
FABP6
fatty acid binding protein 6, ileal
chr10_+_104486253 0.940 ENST00000602868.1
SFXN2
sideroflexin 2
chr17_+_1665306 0.935 ENST00000571360.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_39805976 0.935 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr19_-_7553852 0.934 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr19_-_6604094 0.930 ENST00000597430.2
CD70
CD70 molecule
chr9_-_117160738 0.924 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chr3_+_111717600 0.921 ENST00000273368.4
TAGLN3
transgelin 3
chr5_-_22853429 0.921 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr13_+_77522632 0.911 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr11_+_33037652 0.909 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr17_-_79784533 0.908 ENST00000457257.1
ENST00000576730.1
AC174470.1
FAM195B
AC174470.1
family with sequence similarity 195, member B
chrX_+_55246818 0.902 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr7_-_44122063 0.901 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr17_+_76422409 0.898 ENST00000600087.1
AC061992.1
Uncharacterized protein
chr17_+_42923686 0.896 ENST00000591513.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr19_+_57631411 0.896 ENST00000254181.4
ENST00000600940.1
USP29

ubiquitin specific peptidase 29

chr1_-_55341551 0.887 ENST00000537443.1
DHCR24
24-dehydrocholesterol reductase
chr2_+_127066059 0.880 ENST00000435352.1
AC023347.1
AC023347.1
chr19_-_47128294 0.879 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR




prostaglandin I2 (prostacyclin) receptor (IP)




chr16_-_1922109 0.873 ENST00000496541.2
ENST00000412554.2
ENST00000452149.2
ENST00000397344.3
MEIOB



meiosis specific with OB domains



chr9_+_133986782 0.868 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr1_-_161207986 0.858 ENST00000506209.1
ENST00000367980.2
NR1I3

nuclear receptor subfamily 1, group I, member 3

chr15_-_78913521 0.856 ENST00000326828.5
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr19_-_17366257 0.855 ENST00000594059.1
AC010646.3
Uncharacterized protein
chr14_+_73563735 0.854 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr16_+_67195592 0.838 ENST00000519378.1
FBXL8
F-box and leucine-rich repeat protein 8
chr6_-_32160622 0.836 ENST00000487761.1
ENST00000375040.3
GPSM3

G-protein signaling modulator 3

chr3_-_57260377 0.836 ENST00000495160.2
HESX1
HESX homeobox 1
chr17_-_17480779 0.836 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr16_+_56385290 0.832 ENST00000564727.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr19_+_45174994 0.831 ENST00000403660.3
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr7_+_112262421 0.827 ENST00000453459.1
AC002463.3
AC002463.3
chr19_+_1000418 0.826 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr19_-_49565254 0.825 ENST00000593537.1
NTF4
neurotrophin 4
chr6_-_138893661 0.825 ENST00000427025.2
NHSL1
NHS-like 1
chr19_+_24009879 0.819 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr12_+_54891495 0.814 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr6_+_12007897 0.811 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr11_+_131240373 0.810 ENST00000374791.3
ENST00000436745.1
NTM

neurotrimin

chr3_-_48647470 0.809 ENST00000203407.5
UQCRC1
ubiquinol-cytochrome c reductase core protein I
chr3_+_52007693 0.803 ENST00000494478.1
ABHD14A
abhydrolase domain containing 14A
chr2_-_70520832 0.799 ENST00000454893.1
ENST00000272348.2
SNRPG

small nuclear ribonucleoprotein polypeptide G

chr3_-_113233992 0.797 ENST00000295872.4
ENST00000480527.1
SPICE1

spindle and centriole associated protein 1

chr17_-_8113886 0.786 ENST00000577833.1
ENST00000534871.1
ENST00000583915.1
ENST00000316199.6
ENST00000581511.1
ENST00000585124.1
AURKB





aurora kinase B





chr22_+_25003568 0.785 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr11_-_118213331 0.785 ENST00000392884.2
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr15_-_65398647 0.783 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr1_+_161185032 0.779 ENST00000367992.3
ENST00000289902.1
FCER1G

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide

chr16_+_15596123 0.779 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr16_+_89984287 0.774 ENST00000555147.1
MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr6_+_76599809 0.771 ENST00000430435.1
MYO6
myosin VI
chr6_-_132022635 0.768 ENST00000315453.2
OR2A4
olfactory receptor, family 2, subfamily A, member 4
chr19_+_46003056 0.766 ENST00000401593.1
ENST00000396736.2
PPM1N

protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)

chrX_+_102965835 0.765 ENST00000319560.6
TMEM31
transmembrane protein 31
chr17_+_34058639 0.760 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr7_+_144015218 0.755 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr1_-_9563433 0.750 ENST00000441033.1
RP13-392I16.1
RP13-392I16.1
chr12_+_57157100 0.748 ENST00000322165.1
HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6
chr3_-_149051444 0.747 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr3_-_121448791 0.746 ENST00000489400.1
GOLGB1
golgin B1
chr9_-_72435576 0.746 ENST00000453410.1
ENST00000526458.1
ENST00000439418.1
C9orf135-AS1


C9orf135 antisense RNA 1 (head to head)


chr3_+_52321827 0.743 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK




glycerate kinase




chr17_+_1665345 0.740 ENST00000576406.1
ENST00000571149.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr1_+_201755452 0.738 ENST00000438083.1
NAV1
neuron navigator 1
chr7_-_143956815 0.732 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr19_+_45174724 0.731 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr9_-_86955657 0.731 ENST00000537648.1
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr14_-_90097910 0.728 ENST00000550332.2
RP11-944C7.1
Protein LOC100506792
chr19_+_44085189 0.724 ENST00000562365.2
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr1_+_2407754 0.723 ENST00000419816.2
ENST00000378486.3
ENST00000378488.3
ENST00000288766.5
PLCH2



phospholipase C, eta 2



chr7_-_143929936 0.722 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr12_+_123259063 0.716 ENST00000392441.4
ENST00000539171.1
CCDC62

coiled-coil domain containing 62

chr11_-_65149422 0.714 ENST00000526432.1
ENST00000527174.1
SLC25A45

solute carrier family 25, member 45

chrX_-_71497077 0.714 ENST00000373626.3
RPS4X
ribosomal protein S4, X-linked
chr17_-_17485731 0.712 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr19_-_48614063 0.709 ENST00000599921.1
ENST00000599111.1
PLA2G4C

phospholipase A2, group IVC (cytosolic, calcium-independent)

chr17_+_39994032 0.709 ENST00000293303.4
ENST00000438813.1
KLHL10

kelch-like family member 10

chr3_-_111314230 0.706 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr19_+_44084696 0.704 ENST00000562255.1
ENST00000569031.2
PINLYP

phospholipase A2 inhibitor and LY6/PLAUR domain containing

chr17_-_71258019 0.699 ENST00000344935.4
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr14_-_23762777 0.696 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr11_+_131240593 0.694 ENST00000539799.1
NTM
neurotrimin
chr22_-_30925150 0.693 ENST00000437871.1
SEC14L6
SEC14-like 6 (S. cerevisiae)
chr19_+_41856816 0.692 ENST00000539627.1
TMEM91
transmembrane protein 91
chrX_-_71497148 0.692 ENST00000316084.6
RPS4X
ribosomal protein S4, X-linked
chr19_-_48614033 0.688 ENST00000354276.3
PLA2G4C
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr9_-_86955598 0.688 ENST00000376238.4
SLC28A3
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr19_+_7580103 0.685 ENST00000596712.1
ZNF358
zinc finger protein 358
chr15_-_52404921 0.680 ENST00000561198.1
ENST00000260442.3
BCL2L10

BCL2-like 10 (apoptosis facilitator)

chr13_+_77526602 0.673 ENST00000449753.1
IRG1
immunoresponsive 1 homolog (mouse)
chr4_-_74864386 0.672 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr11_-_118213455 0.672 ENST00000300692.4
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr15_-_65903512 0.669 ENST00000567923.1
VWA9
von Willebrand factor A domain containing 9
chr12_-_105478339 0.664 ENST00000424857.2
ENST00000258494.9
ALDH1L2

aldehyde dehydrogenase 1 family, member L2

chr11_+_308143 0.663 ENST00000399817.4
IFITM2
interferon induced transmembrane protein 2
chr2_-_74692473 0.659 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
MOGS





mannosyl-oligosaccharide glucosidase





chr19_-_46142680 0.657 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr15_-_42076229 0.656 ENST00000597767.1
AC073657.1
Uncharacterized protein
chr19_-_55677999 0.656 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr12_+_57810198 0.655 ENST00000598001.1
AC126614.1
HCG1818482; Uncharacterized protein
chr9_-_35658007 0.652 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr10_-_30638090 0.651 ENST00000421701.1
ENST00000263063.4
MTPAP

mitochondrial poly(A) polymerase

chr11_+_308217 0.650 ENST00000602569.1
IFITM2
interferon induced transmembrane protein 2
chr19_-_46142637 0.647 ENST00000590043.1
ENST00000589876.1
EML2

echinoderm microtubule associated protein like 2

chr22_-_32766972 0.647 ENST00000382084.4
ENST00000382086.2
RFPL3S

RFPL3 antisense

chr16_-_90096309 0.644 ENST00000408886.2
C16orf3
chromosome 16 open reading frame 3
chr12_-_57644952 0.642 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3



SH3 and cysteine rich domain 3



chr1_-_59165763 0.640 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr2_-_74645669 0.638 ENST00000518401.1
C2orf81
chromosome 2 open reading frame 81

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.7 2.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6 5.7 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.6 2.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 2.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.4 4.5 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.4 2.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.3 1.7 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.3 1.6 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.3 1.9 GO:1904970 brush border assembly(GO:1904970)
0.3 1.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.3 2.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 1.7 GO:0006710 androgen catabolic process(GO:0006710)
0.3 1.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.3 1.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 0.8 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.3 0.8 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 0.7 GO:0006059 hexitol metabolic process(GO:0006059)
0.2 0.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 1.2 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.2 1.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.2 0.8 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 1.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 4.2 GO:0097264 self proteolysis(GO:0097264)
0.2 2.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 4.4 GO:0045141 meiotic telomere clustering(GO:0045141)
0.2 0.8 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.2 2.6 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.2 0.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 2.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 2.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 0.7 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.2 1.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.7 GO:0090410 malonate catabolic process(GO:0090410)
0.2 1.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.2 0.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 0.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 0.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.2 1.5 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.2 0.5 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.2 0.5 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.9 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 1.0 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 3.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.6 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.1 4.7 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.3 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.1 3.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.5 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.1 0.9 GO:0019236 response to pheromone(GO:0019236)
0.1 0.7 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 0.7 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 1.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.5 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 2.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.9 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.5 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 1.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 1.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.6 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.8 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 2.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.4 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.1 1.3 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.3 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.3 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 1.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.3 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 1.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 5.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 1.5 GO:0015866 ADP transport(GO:0015866)
0.1 0.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.4 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.4 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 0.9 GO:0007144 female meiosis I(GO:0007144)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.3 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.3 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.7 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.5 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1 0.3 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 2.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 2.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.2 GO:0001878 response to yeast(GO:0001878)
0.1 0.2 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.2 GO:0006949 syncytium formation(GO:0006949)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.3 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 1.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 0.4 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.4 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.0 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.2 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 2.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 1.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.5 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:1900114 positive regulation of histone H3-K9 dimethylation(GO:1900111) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.1 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 4.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.1 GO:0032796 uropod organization(GO:0032796)
0.1 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.5 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 1.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular response to luteinizing hormone stimulus(GO:0071373)
0.1 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.9 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.3 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 1.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 1.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 1.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.6 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0018194 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 1.8 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) glycoprotein transport(GO:0034436)
0.0 0.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.3 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.8 GO:0051272 positive regulation of locomotion(GO:0040017) positive regulation of cellular component movement(GO:0051272) positive regulation of cell motility(GO:2000147)
0.0 0.1 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.6 GO:1904874 positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0042640 anagen(GO:0042640)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 2.4 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0051413 response to cortisone(GO:0051413)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.3 GO:1990834 response to odorant(GO:1990834)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 2.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0 0.3 GO:0010820 regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0046874 quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.4 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 1.0 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.4 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 3.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 4.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:1902661 regulation of histone H3-K9 dimethylation(GO:1900109) negative regulation of histone H3-K9 dimethylation(GO:1900110) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0 0.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.7 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.3 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 3.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 2.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 1.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.7 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.7 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.1 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.2 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.8 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0071352 cellular response to interleukin-2(GO:0071352)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.2 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 1.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0098743 cell aggregation(GO:0098743)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0009304 tRNA transcription(GO:0009304)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.2 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.0 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.6 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.2 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.0 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.1 GO:0009584 detection of visible light(GO:0009584)
0.0 0.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0051584 regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.3 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0043226 organelle(GO:0043226)
0.3 1.8 GO:0036021 endolysosome lumen(GO:0036021)
0.3 1.8 GO:0045298 tubulin complex(GO:0045298)
0.2 0.9 GO:0055087 Ski complex(GO:0055087)
0.2 0.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.2 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.3 GO:0031209 SCAR complex(GO:0031209)
0.1 2.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 3.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 2.6 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.9 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 0.3 GO:0098798 mitochondrial protein complex(GO:0098798)
0.1 1.7 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.6 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.5 GO:0071817 MMXD complex(GO:0071817)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 2.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.2 GO:0009346 citrate lyase complex(GO:0009346)
0.1 5.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.6 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 2.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.1 GO:0005869 dynactin complex(GO:0005869)
0.1 0.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.8 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.3 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0070847 core mediator complex(GO:0070847)
0.0 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.8 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 3.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.0 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.9 GO:0019867 outer membrane(GO:0019867)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 2.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.3 GO:0016020 membrane(GO:0016020)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 6.1 GO:0043209 myelin sheath(GO:0043209)
0.0 8.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0005767 secondary lysosome(GO:0005767)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0097486 late endosome lumen(GO:0031906) multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 7.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 2.4 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0001741 XY body(GO:0001741)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.6 1.7 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.5 1.5 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.5 3.0 GO:0004882 androgen receptor activity(GO:0004882)
0.5 1.8 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.4 1.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.4 1.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 1.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.3 4.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 2.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.3 0.8 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 0.7 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.2 1.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 7.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 3.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.0 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.2 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 0.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 2.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.8 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 0.7 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.2 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 0.7 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.2 1.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.7 GO:0019863 IgE binding(GO:0019863)
0.2 1.0 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.9 GO:0003883 CTP synthase activity(GO:0003883)
0.2 0.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 4.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.0 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 0.7 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.2 1.1 GO:0016936 galactoside binding(GO:0016936)
0.2 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 1.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.6 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.7 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 2.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.9 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0070905 serine binding(GO:0070905)
0.1 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 0.6 GO:1902444 riboflavin binding(GO:1902444)
0.1 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.3 GO:0030984 kininogen binding(GO:0030984)
0.1 0.3 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 1.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.3 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 0.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.8 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.4 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.9 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.3 GO:0032052 bile acid binding(GO:0032052)
0.1 0.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 1.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.2 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.3 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.5 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.2 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 2.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 1.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.1 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.9 GO:0016594 glycine binding(GO:0016594)
0.1 0.6 GO:0015250 water channel activity(GO:0015250)
0.1 0.3 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.9 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 2.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.4 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 4.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.6 GO:0000182 rDNA binding(GO:0000182)
0.0 0.6 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.6 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 2.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 2.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0000832 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.7 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 4.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0004540 ribonuclease activity(GO:0004540)
0.0 4.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.6 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.2 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 1.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.3 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 0.6 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 2.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 3.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.3 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.1 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.3 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.1 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID_IL27_PATHWAY IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 4.6 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.2 4.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 1.8 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 3.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 2.1 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 4.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.2 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.5 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.9 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.1 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.1 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.5 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.9 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.9 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 3.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.5 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 1.0 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 2.3 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 3.6 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.8 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.1 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 1.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 1.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 2.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 2.2 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 3.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 2.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 1.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 1.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.3 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.5 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.3 REACTOME_PURINE_METABOLISM Genes involved in Purine metabolism
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC