Motif ID: PDX1

Z-value: 0.352


Transcription factors associated with PDX1:

Gene SymbolEntrez IDGene Name
PDX1 ENSG00000139515.5 PDX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PDX1hg19_v2_chr13_+_28494130_284941680.314.2e-01Click!


Activity profile for motif PDX1.

activity profile for motif PDX1


Sorted Z-values histogram for motif PDX1

Sorted Z-values for motif PDX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_30721968 0.339 ENST00000361762.2
PCDH7
protocadherin 7
chr17_+_72427477 0.324 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr8_+_32579271 0.311 ENST00000518084.1
NRG1
neuregulin 1
chr8_+_32579341 0.298 ENST00000519240.1
ENST00000539990.1
NRG1

neuregulin 1

chr8_+_32579321 0.292 ENST00000522402.1
NRG1
neuregulin 1
chr14_-_54423529 0.270 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr4_+_169013666 0.211 ENST00000359299.3
ANXA10
annexin A10
chr12_-_86230315 0.207 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr5_-_141249154 0.197 ENST00000357517.5
ENST00000536585.1
PCDH1

protocadherin 1

chr5_-_115890554 0.190 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr7_+_114055052 0.184 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr1_+_62439037 0.183 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr4_-_36245561 0.178 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_145277569 0.176 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr11_+_130318869 0.152 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr4_-_139163491 0.151 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_-_145188137 0.150 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_28261533 0.144 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr17_-_39150385 0.139 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr14_+_39944025 0.135 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr11_+_118403747 0.134 ENST00000526853.1
TMEM25
transmembrane protein 25
chr18_+_32173276 0.127 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr10_+_24497704 0.126 ENST00000376456.4
ENST00000458595.1
KIAA1217

KIAA1217

chr22_-_28490123 0.125 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr6_-_32157947 0.122 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_-_8285405 0.118 ENST00000335790.3
ENST00000534484.1
LMO1

LIM domain only 1 (rhombotin 1)

chr17_-_39156138 0.118 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chrX_-_106243451 0.114 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr10_+_24738355 0.114 ENST00000307544.6
KIAA1217
KIAA1217
chr4_+_86525299 0.112 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr9_+_125133315 0.110 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr7_-_92777606 0.110 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chrX_-_106243294 0.109 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr1_-_232651312 0.107 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr2_-_190927447 0.106 ENST00000260950.4
MSTN
myostatin
chr4_+_77356248 0.105 ENST00000296043.6
SHROOM3
shroom family member 3
chr5_+_173930676 0.101 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chrX_+_10126488 0.098 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4


chloride channel, voltage-sensitive 4


chr4_-_109541610 0.097 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr17_-_27418537 0.094 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr8_+_92261516 0.091 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr11_-_36619771 0.089 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr20_+_42523336 0.086 ENST00000428529.1
RP5-1030M6.3
RP5-1030M6.3
chr1_-_21625486 0.085 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr7_-_14029283 0.084 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr18_+_3447572 0.081 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr17_-_27467418 0.078 ENST00000528564.1
MYO18A
myosin XVIIIA
chr14_-_77889860 0.077 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr7_-_14028488 0.076 ENST00000405358.4
ETV1
ets variant 1
chr10_+_118083919 0.075 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr10_-_56561022 0.074 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15













protocadherin-related 15













chr14_-_92247032 0.073 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB


catsper channel auxiliary subunit beta


chr12_-_45269251 0.070 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr9_+_125132803 0.067 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_28586006 0.067 ENST00000253063.3
SESN2
sestrin 2
chr12_-_16762971 0.066 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr21_+_29911640 0.066 ENST00000412526.1
ENST00000455939.1
LINC00161

long intergenic non-protein coding RNA 161

chr2_-_166930131 0.065 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr2_+_191208601 0.064 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1


inositol polyphosphate-1-phosphatase


chrX_+_10031499 0.061 ENST00000454666.1
WWC3
WWC family member 3
chr4_-_140544386 0.061 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr2_+_191208656 0.060 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr11_+_35222629 0.060 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr5_-_96478466 0.060 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr3_+_69985734 0.059 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr11_+_115498761 0.059 ENST00000424313.2
AP000997.1
AP000997.1
chr15_+_43886057 0.059 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B


creatine kinase, mitochondrial 1B


chr4_+_119810134 0.059 ENST00000434046.2
SYNPO2
synaptopodin 2
chr5_-_142780280 0.058 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr20_+_43029911 0.058 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A


hepatocyte nuclear factor 4, alpha


chr10_+_11047259 0.058 ENST00000379261.4
ENST00000416382.2
CELF2

CUGBP, Elav-like family member 2

chr2_+_191208791 0.056 ENST00000423767.1
ENST00000451089.1
INPP1

inositol polyphosphate-1-phosphatase

chr13_-_67802549 0.056 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr12_-_16761007 0.056 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr3_+_69985792 0.055 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chrX_-_13835147 0.053 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr8_+_50824233 0.052 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr3_-_143567262 0.051 ENST00000474151.1
ENST00000316549.6
SLC9A9

solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9

chrX_-_106146547 0.051 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr5_-_56778635 0.051 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr21_+_17443434 0.050 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr11_-_8290263 0.049 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr19_-_7697857 0.049 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr15_+_59910132 0.049 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr20_+_42984330 0.049 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr7_+_6655225 0.048 ENST00000457543.3
ZNF853
zinc finger protein 853
chr1_-_10532531 0.048 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr19_+_641178 0.048 ENST00000166133.3
FGF22
fibroblast growth factor 22
chr17_-_39123144 0.045 ENST00000355612.2
KRT39
keratin 39
chr13_+_78315528 0.044 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr12_+_72332618 0.043 ENST00000333850.3
TPH2
tryptophan hydroxylase 2
chr4_+_53525573 0.043 ENST00000503051.1
USP46-AS1
USP46 antisense RNA 1
chr6_+_39760129 0.042 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr7_-_73038822 0.042 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL


MLX interacting protein-like


chrX_+_49020882 0.042 ENST00000454342.1
MAGIX
MAGI family member, X-linked
chr6_+_126221034 0.041 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr3_-_98235962 0.041 ENST00000513873.1
CLDND1
claudin domain containing 1
chr8_-_42358742 0.041 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr2_+_166152283 0.039 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr4_+_66536248 0.039 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr7_-_115670792 0.039 ENST00000265440.7
ENST00000393485.1
TFEC

transcription factor EC

chr9_+_136501478 0.038 ENST00000393056.2
ENST00000263611.2
DBH

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

chr12_-_53171128 0.037 ENST00000332411.2
KRT76
keratin 76
chr18_+_57567180 0.036 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chr1_-_190446759 0.036 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_41884620 0.036 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr7_-_115670804 0.036 ENST00000320239.7
TFEC
transcription factor EC
chr4_+_71587669 0.036 ENST00000381006.3
ENST00000226328.4
RUFY3

RUN and FYVE domain containing 3

chr13_+_78315466 0.036 ENST00000314070.5
ENST00000462234.1
SLAIN1

SLAIN motif family, member 1

chr12_+_32638897 0.035 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr4_-_41884582 0.035 ENST00000499082.2
LINC00682
long intergenic non-protein coding RNA 682
chr2_-_180427304 0.035 ENST00000336917.5
ZNF385B
zinc finger protein 385B
chrX_+_72783026 0.035 ENST00000373504.6
ENST00000373502.5
CHIC1

cysteine-rich hydrophobic domain 1

chr11_-_124981475 0.035 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218











transmembrane protein 218











chr12_-_94673956 0.035 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr10_+_119302508 0.034 ENST00000442245.4
EMX2
empty spiracles homeobox 2
chr4_+_95916947 0.034 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr9_-_5339873 0.034 ENST00000223862.1
ENST00000223858.4
RLN1

relaxin 1

chr20_-_271304 0.033 ENST00000400269.3
ENST00000360321.2
C20orf96

chromosome 20 open reading frame 96

chr20_+_43538756 0.033 ENST00000537323.1
ENST00000217073.2
PABPC1L

poly(A) binding protein, cytoplasmic 1-like

chr8_+_22844995 0.033 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr7_-_73038867 0.032 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL



MLX interacting protein-like



chr15_+_51669444 0.032 ENST00000396399.2
GLDN
gliomedin
chr5_+_98109322 0.031 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr1_+_198608146 0.031 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr20_+_43538692 0.031 ENST00000217074.4
ENST00000255136.3
PABPC1L

poly(A) binding protein, cytoplasmic 1-like

chr8_+_9953214 0.030 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr10_-_21186144 0.030 ENST00000377119.1
NEBL
nebulette
chr3_-_167191814 0.030 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr8_+_9953061 0.030 ENST00000522907.1
ENST00000528246.1
MSRA

methionine sulfoxide reductase A

chr3_-_38071122 0.029 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr11_-_102496063 0.029 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr15_+_69854027 0.029 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr12_-_50643664 0.029 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr19_-_56135928 0.029 ENST00000591479.1
ENST00000325351.4
ZNF784

zinc finger protein 784

chr4_-_103749205 0.028 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_39979576 0.028 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr17_-_40337470 0.027 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr8_-_7243080 0.026 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr2_-_112237835 0.026 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG

MIR4435-1 host gene (non-protein coding)

chr1_-_151965048 0.026 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr11_-_102709441 0.026 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr4_-_66536196 0.025 ENST00000511294.1
EPHA5
EPH receptor A5
chr18_+_32558208 0.025 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_-_103749179 0.025 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_221509638 0.024 ENST00000439004.1
RP11-421L10.1
RP11-421L10.1
chr6_+_45296391 0.024 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr6_+_34204642 0.023 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr4_-_103749105 0.023 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr17_+_74846230 0.023 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr17_+_73539339 0.022 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr9_-_13165457 0.022 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr18_+_59000815 0.022 ENST00000262717.4
CDH20
cadherin 20, type 2
chr11_+_112041253 0.022 ENST00000532612.1
AP002884.3
AP002884.3
chr15_-_33180439 0.021 ENST00000559610.1
FMN1
formin 1
chr1_-_1710229 0.021 ENST00000341991.3
NADK
NAD kinase
chr3_-_131756559 0.021 ENST00000505957.1
CPNE4
copine IV
chr12_-_16430619 0.020 ENST00000344941.3
SLC15A5
solute carrier family 15, member 5
chr4_-_103749313 0.020 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_1709845 0.020 ENST00000341426.5
ENST00000344463.4
NADK

NAD kinase

chr9_-_5304432 0.020 ENST00000416837.1
ENST00000308420.3
RLN2

relaxin 2

chr4_+_119809984 0.020 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2


synaptopodin 2


chr15_+_43885799 0.019 ENST00000449946.1
ENST00000417289.1
CKMT1B

creatine kinase, mitochondrial 1B

chr9_+_131062367 0.019 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr8_+_22844913 0.019 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr12_+_81101277 0.019 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr7_+_129015671 0.019 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr7_+_50348268 0.019 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr9_+_135457530 0.019 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr5_+_172068232 0.018 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B


neuralized E3 ubiquitin protein ligase 1B


chr5_-_54988448 0.018 ENST00000503817.1
ENST00000512595.1
SLC38A9

solute carrier family 38, member 9

chr12_-_16761117 0.017 ENST00000538051.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_119759795 0.017 ENST00000419654.2
SEC24D
SEC24 family member D
chr4_-_53525406 0.017 ENST00000451218.2
ENST00000441222.3
USP46

ubiquitin specific peptidase 46

chr16_-_85617170 0.017 ENST00000602862.1
RP11-118F19.1
RP11-118F19.1
chr20_-_56647116 0.016 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1

RP13-379L11.1

chr4_-_109541539 0.016 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1


RPL34 antisense RNA 1 (head to head)


chr12_-_109221160 0.016 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr5_-_36301984 0.016 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr6_-_100912785 0.016 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr11_+_110001723 0.016 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_-_183622442 0.015 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr10_-_74714533 0.015 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr4_-_66536057 0.015 ENST00000273854.3
EPHA5
EPH receptor A5
chr5_+_137722255 0.014 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr4_+_95128748 0.014 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr20_+_30697298 0.014 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr4_+_105828492 0.013 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr17_-_8301132 0.013 ENST00000399398.2
RNF222
ring finger protein 222
chr4_-_103748880 0.013 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr2_+_109204743 0.013 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr20_-_49307897 0.013 ENST00000535356.1
FAM65C
family with sequence similarity 65, member C
chr15_+_43986069 0.013 ENST00000415044.1
CKMT1A
creatine kinase, mitochondrial 1A
chr20_-_50418972 0.013 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr2_+_138721850 0.012 ENST00000329366.4
ENST00000280097.3
HNMT

histamine N-methyltransferase

chr5_-_134735568 0.012 ENST00000510038.1
ENST00000304332.4
H2AFY

H2A histone family, member Y

chr5_-_54988559 0.012 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr8_+_55528627 0.012 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr3_+_107244229 0.012 ENST00000456419.1
ENST00000402163.2
BBX

bobby sox homolog (Drosophila)

chr11_-_40315640 0.011 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.3 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.3 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling