Motif ID: PAX6

Z-value: 0.712


Transcription factors associated with PAX6:

Gene SymbolEntrez IDGene Name
PAX6 ENSG00000007372.16 PAX6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX6hg19_v2_chr11_-_31839488_31839515-0.343.6e-01Click!


Activity profile for motif PAX6.

activity profile for motif PAX6


Sorted Z-values histogram for motif PAX6

Sorted Z-values for motif PAX6



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_10007448 0.911 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr14_+_88471468 0.774 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr16_-_80926457 0.734 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1

RP11-314O13.1

chr18_-_45663666 0.636 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr12_-_45270077 0.551 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chrX_+_148769880 0.528 ENST00000412632.2
MAGEA11
melanoma antigen family A, 11
chr6_-_33041378 0.478 ENST00000428995.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr12_-_45269430 0.431 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr12_-_45270151 0.415 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr6_-_137366163 0.414 ENST00000367748.1
IL20RA
interleukin 20 receptor, alpha
chr12_-_45269251 0.392 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chrX_+_37545012 0.377 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr8_-_19615382 0.376 ENST00000544602.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr19_-_14911023 0.374 ENST00000248073.2
OR7C1
olfactory receptor, family 7, subfamily C, member 1
chr2_-_162931052 0.319 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr12_-_45269769 0.310 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr1_-_204183071 0.300 ENST00000308302.3
GOLT1A
golgi transport 1A
chr2_+_132160448 0.300 ENST00000437751.1
AC073869.19
long intergenic non-protein coding RNA 1120
chr17_+_25958174 0.299 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9



lectin, galactoside-binding, soluble, 9



chr12_-_121476959 0.291 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr19_+_35820064 0.291 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22











CD22 molecule











chr6_+_125474939 0.282 ENST00000527711.1
TPD52L1
tumor protein D52-like 1
chr6_+_125474992 0.279 ENST00000528193.1
TPD52L1
tumor protein D52-like 1
chr6_+_125475335 0.277 ENST00000532429.1
ENST00000534199.1
TPD52L1

tumor protein D52-like 1

chr6_-_137366096 0.268 ENST00000316649.5
ENST00000367746.3
IL20RA

interleukin 20 receptor, alpha

chr11_-_58343319 0.265 ENST00000395074.2
LPXN
leupaxin
chr3_-_171489085 0.261 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr8_+_21882244 0.258 ENST00000289820.6
ENST00000381530.5
NPM2

nucleophosmin/nucleoplasmin 2

chr5_+_140602904 0.255 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr8_-_19615435 0.250 ENST00000523262.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr4_-_798689 0.250 ENST00000504062.1
CPLX1
complexin 1
chr3_-_124839648 0.248 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr1_+_104104379 0.243 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr12_+_113416340 0.237 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr7_-_80551671 0.236 ENST00000419255.2
ENST00000544525.1
SEMA3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

chr18_-_21242774 0.236 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr6_+_125474795 0.234 ENST00000304877.13
ENST00000534000.1
ENST00000368402.5
ENST00000368388.2
TPD52L1



tumor protein D52-like 1



chrX_+_10126488 0.229 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4


chloride channel, voltage-sensitive 4


chr11_+_111789580 0.229 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr8_-_19614810 0.224 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr18_-_21242833 0.220 ENST00000586087.1
ENST00000592179.1
ANKRD29

ankyrin repeat domain 29

chr12_+_93115281 0.220 ENST00000549856.1
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr3_+_108015382 0.211 ENST00000463019.3
ENST00000491820.1
ENST00000467562.1
ENST00000482430.1
ENST00000462629.1
HHLA2




HERV-H LTR-associating 2




chr1_-_232598163 0.210 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_+_77356248 0.189 ENST00000296043.6
SHROOM3
shroom family member 3
chr2_+_191334212 0.188 ENST00000444317.1
ENST00000535751.1
MFSD6

major facilitator superfamily domain containing 6

chr8_-_18711866 0.188 ENST00000519851.1
PSD3
pleckstrin and Sec7 domain containing 3
chr6_-_26033796 0.177 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr5_-_141338377 0.174 ENST00000510041.1
PCDH12
protocadherin 12
chr8_-_27469383 0.173 ENST00000519742.1
CLU
clusterin
chr12_-_78934441 0.172 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1

RP11-171L9.1

chr6_-_26043885 0.172 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr11_-_87908600 0.169 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38


RAB38, member RAS oncogene family


chr1_-_8585945 0.168 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr11_+_118175132 0.166 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr5_-_55529115 0.164 ENST00000513241.2
ENST00000341048.4
ANKRD55

ankyrin repeat domain 55

chr10_+_91092241 0.161 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr7_-_97501706 0.153 ENST00000455086.1
ENST00000453600.1
ASNS

asparagine synthetase (glutamine-hydrolyzing)

chr10_-_13523073 0.153 ENST00000440282.1
BEND7
BEN domain containing 7
chr6_-_10412600 0.151 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr18_-_21242729 0.150 ENST00000585908.2
ANKRD29
ankyrin repeat domain 29
chr12_+_113354341 0.150 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr21_-_35884573 0.150 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr8_-_19615538 0.148 ENST00000517494.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_-_8586084 0.145 ENST00000464972.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr17_-_58499698 0.142 ENST00000590297.1
USP32
ubiquitin specific peptidase 32
chr4_+_40751914 0.136 ENST00000381782.2
ENST00000316607.5
NSUN7

NOP2/Sun domain family, member 7

chrX_-_13835147 0.131 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr18_+_32173276 0.129 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr17_+_36283971 0.127 ENST00000327454.6
ENST00000378174.5
TBC1D3F

TBC1 domain family, member 3F

chr9_-_116861337 0.126 ENST00000374118.3
KIF12
kinesin family member 12
chr5_-_114938090 0.126 ENST00000427199.2
TICAM2
toll-like receptor adaptor molecule 2
chr10_-_82049424 0.126 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr14_+_61995722 0.125 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr8_+_30496078 0.124 ENST00000517349.1
SMIM18
small integral membrane protein 18
chr9_-_14180778 0.123 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr2_+_145780662 0.122 ENST00000423031.1
TEX41
testis expressed 41 (non-protein coding)
chr11_+_128563652 0.120 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_-_97501733 0.120 ENST00000444334.1
ENST00000422745.1
ENST00000394308.3
ENST00000451771.1
ENST00000175506.4
ASNS




asparagine synthetase (glutamine-hydrolyzing)




chr1_+_79115503 0.118 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr19_-_36019123 0.118 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr7_-_14029283 0.115 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr5_+_322733 0.115 ENST00000515206.1
AHRR
aryl-hydrocarbon receptor repressor
chr12_-_69080590 0.114 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2

RP11-637A17.2

chr5_-_142077569 0.109 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1


fibroblast growth factor 1 (acidic)


chr3_-_195310802 0.109 ENST00000421243.1
ENST00000453131.1
APOD

apolipoprotein D

chr2_-_86116020 0.108 ENST00000525834.2
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr9_-_95166884 0.105 ENST00000375561.5
OGN
osteoglycin
chr3_-_15563229 0.104 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
COLQ




collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase




chr4_-_187517928 0.102 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr6_+_25652432 0.101 ENST00000377961.2
SCGN
secretagogin, EF-hand calcium binding protein
chr1_+_26758790 0.099 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
DHDDS





dehydrodolichyl diphosphate synthase





chr17_+_43224684 0.098 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr2_+_232135245 0.098 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr7_-_76255444 0.097 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_-_36906474 0.097 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr1_+_26759295 0.097 ENST00000430232.1
DHDDS
dehydrodolichyl diphosphate synthase
chr11_-_61849656 0.093 ENST00000524942.1
RP11-810P12.5
RP11-810P12.5
chr17_-_60883993 0.092 ENST00000583803.1
ENST00000456609.2
MARCH10

membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase

chr17_-_39023462 0.092 ENST00000251643.4
KRT12
keratin 12
chr2_+_220363579 0.090 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA






GDP-mannose pyrophosphorylase A






chr19_+_49891533 0.088 ENST00000598730.1
ENST00000594905.1
ENST00000595828.1
ENST00000594043.1
CCDC155



coiled-coil domain containing 155



chr1_-_21620877 0.088 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr4_-_129491686 0.087 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr21_-_16031122 0.086 ENST00000400562.1
AF165138.7
Protein LOC388813
chr1_-_185597619 0.080 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1

GS1-204I12.1

chr8_-_62602327 0.080 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr19_-_22806764 0.080 ENST00000598042.1
AC011516.2
AC011516.2
chr4_-_10686475 0.079 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr6_+_26156551 0.078 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr1_+_26758849 0.078 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
DHDDS






dehydrodolichyl diphosphate synthase






chr6_-_138060103 0.078 ENST00000411615.1
ENST00000419220.1
RP11-356I2.1

RP11-356I2.1

chr6_+_41748500 0.077 ENST00000458694.1
ENST00000359201.5
PRICKLE4

prickle homolog 4 (Drosophila)

chr5_+_93954039 0.077 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr12_+_56915713 0.077 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr2_-_220110111 0.077 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L



galactosidase, beta 1-like



chr5_-_159766528 0.076 ENST00000505287.2
CCNJL
cyclin J-like
chr7_-_152373216 0.075 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr5_+_17404147 0.074 ENST00000507730.1
RP11-321E2.3
RP11-321E2.3
chr20_+_48807351 0.073 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr4_+_123747979 0.070 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr1_-_184006829 0.069 ENST00000361927.4
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr5_+_118668846 0.068 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr4_+_123747834 0.067 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr14_-_50065882 0.066 ENST00000539688.1
AL139099.1
Full-length cDNA clone CS0DK012YO09 of HeLa cells of Homo sapiens (human); Uncharacterized protein
chr5_+_85913721 0.066 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C


cytochrome c oxidase subunit VIIc


chr4_+_87928140 0.066 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr8_+_41347915 0.066 ENST00000518270.1
ENST00000520817.1
GOLGA7

golgin A7

chr19_-_54327542 0.065 ENST00000391775.3
ENST00000324134.6
ENST00000535162.1
ENST00000351894.4
ENST00000354278.3
ENST00000391773.1
ENST00000345770.5
ENST00000391772.1
NLRP12







NLR family, pyrin domain containing 12







chr9_-_95166976 0.065 ENST00000447356.1
OGN
osteoglycin
chr5_+_94982558 0.063 ENST00000311364.4
ENST00000458310.1
RFESD

Rieske (Fe-S) domain containing

chr1_+_108992904 0.062 ENST00000370040.3
ENST00000495380.2
ENST00000531446.1
NBPF6


neuroblastoma breakpoint family, member 6


chr5_-_159546396 0.061 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A


PWWP domain containing 2A


chr2_+_149402989 0.061 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_-_196910477 0.060 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr7_+_138943265 0.060 ENST00000483726.1
UBN2
ubinuclein 2
chr2_+_238877424 0.059 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr12_-_24097236 0.059 ENST00000538083.1
SOX5
SRY (sex determining region Y)-box 5
chr12_+_56915776 0.059 ENST00000550726.1
ENST00000542360.1
RBMS2

RNA binding motif, single stranded interacting protein 2

chr2_+_109204743 0.057 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_37701386 0.057 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
ZNF585B


zinc finger protein 585B


chr8_+_18067602 0.057 ENST00000307719.4
ENST00000545197.1
ENST00000539092.1
ENST00000541942.1
ENST00000518029.1
NAT1




N-acetyltransferase 1 (arylamine N-acetyltransferase)




chr19_+_3708376 0.056 ENST00000539908.2
TJP3
tight junction protein 3
chr7_+_102292796 0.056 ENST00000436228.2
SPDYE2B
speedy/RINGO cell cycle regulator family member E2B
chr3_-_58652523 0.055 ENST00000489857.1
ENST00000358781.2
FAM3D

family with sequence similarity 3, member D

chr1_-_55089191 0.055 ENST00000302250.2
ENST00000371304.2
FAM151A

family with sequence similarity 151, member A

chr5_+_322685 0.055 ENST00000510400.1
AHRR
aryl-hydrocarbon receptor repressor
chr8_-_17103951 0.054 ENST00000520178.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr10_+_97471508 0.054 ENST00000453258.2
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr2_-_86116093 0.052 ENST00000377332.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_-_202298268 0.052 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr7_+_45067265 0.052 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr1_-_211666259 0.052 ENST00000367002.4
RD3
retinal degeneration 3
chr19_+_42037433 0.051 ENST00000599316.1
ENST00000599770.1
AC006129.1

AC006129.1

chr1_+_203651937 0.051 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr6_-_42162654 0.050 ENST00000230361.3
GUCA1B
guanylate cyclase activator 1B (retina)
chr4_+_40194609 0.050 ENST00000508513.1
RHOH
ras homolog family member H
chr2_-_154335300 0.050 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr5_+_96212185 0.050 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chrX_-_53461288 0.050 ENST00000375298.4
ENST00000375304.5
HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

chr2_+_101223490 0.049 ENST00000414647.1
ENST00000424342.1
AC068538.4

AC068538.4

chr17_-_36956155 0.048 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chrX_-_138914394 0.047 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C



ATPase, class VI, type 11C



chr3_-_196910721 0.047 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr8_-_33370607 0.047 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr4_+_114066764 0.046 ENST00000511380.1
ANK2
ankyrin 2, neuronal
chr17_-_3819751 0.046 ENST00000225538.3
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr13_-_45768841 0.046 ENST00000379108.1
KCTD4
potassium channel tetramerization domain containing 4
chr2_+_109204909 0.045 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_-_30684898 0.045 ENST00000422266.1
ENST00000416571.1
MDC1

mediator of DNA-damage checkpoint 1

chr12_+_10460417 0.045 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1


killer cell lectin-like receptor subfamily D, member 1


chrX_-_53461305 0.045 ENST00000168216.6
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr20_-_1472029 0.044 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr11_-_102401469 0.043 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr4_+_70861647 0.043 ENST00000246895.4
ENST00000381060.2
STATH

statherin

chr1_-_156269428 0.043 ENST00000339922.3
VHLL
von Hippel-Lindau tumor suppressor-like
chr8_+_16884740 0.042 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr11_+_74811578 0.042 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr8_-_79470728 0.040 ENST00000522807.1
ENST00000519242.1
ENST00000522302.1
RP11-594N15.2


RP11-594N15.2


chr6_+_1080164 0.040 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr5_+_119799927 0.040 ENST00000407149.2
ENST00000379551.2
PRR16

proline rich 16

chr14_+_32547434 0.039 ENST00000556191.1
ENST00000554090.1
ARHGAP5

Rho GTPase activating protein 5

chr22_-_17702729 0.038 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
CECR1


cat eye syndrome chromosome region, candidate 1


chr4_-_88141615 0.038 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
KLHL8


kelch-like family member 8


chr4_-_16077741 0.037 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1


prominin 1


chr3_-_15540055 0.037 ENST00000605797.1
ENST00000435459.2
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr1_-_110933663 0.037 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4


solute carrier family 16, member 4


chr17_+_16945820 0.037 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr17_+_57297807 0.036 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1


glycerophosphodiester phosphodiesterase domain containing 1


chr12_-_133485733 0.035 ENST00000540537.1
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr16_+_4897912 0.035 ENST00000545171.1
UBN1
ubinuclein 1
chr9_+_127023704 0.035 ENST00000373596.1
ENST00000425237.1
NEK6

NIMA-related kinase 6

chr3_-_18486354 0.035 ENST00000493952.2
ENST00000440737.1
SATB1

SATB homeobox 1

chr19_+_36266433 0.034 ENST00000314737.5
ARHGAP33
Rho GTPase activating protein 33
chr2_+_228190066 0.034 ENST00000436237.1
ENST00000443428.2
ENST00000418961.1
MFF


mitochondrial fission factor


chr6_+_30844192 0.034 ENST00000502955.1
ENST00000505066.1
DDR1

discoidin domain receptor tyrosine kinase 1

chr5_+_321810 0.034 ENST00000514523.1
AHRR
aryl-hydrocarbon receptor repressor
chr4_-_88141755 0.034 ENST00000273963.5
KLHL8
kelch-like family member 8
chr2_+_196521903 0.034 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr1_+_158901329 0.034 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1




pyrin and HIN domain family, member 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.1 1.0 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 2.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:2001190 natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.3 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.8 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.0 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.7 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588) regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.1 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.3 GO:0005534 galactose binding(GO:0005534)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.0 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 1.1 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis