ISMARA results: OTP_PHOX2B_LHX1_LMX1A_LHX5

Motif ID: OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Z-value: 0.396

Transcription factors associated with OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4:

Gene Symbol	Entrez ID	Gene Name
HOXC4	ENSG00000198353.6	HOXC4
HOXC4	ENSG00000273266.1	HOXC4
LHX1	ENSG00000132130.7	LHX1
LHX5	ENSG00000089116.3	LHX5
LMX1A	ENSG00000162761.10	LMX1A
OTP	ENSG00000171540.6	OTP
PHOX2B	ENSG00000109132.5	PHOX2B

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
HOXC4	hg19_v2_chr12_+_54447637_54447661	0.57	1.1e-01	Click!
LHX1	hg19_v2_chr17_+_35294075_35294102	-0.40	2.9e-01	Click!
OTP	hg19_v2_chr5_-_76935513_76935513	-0.37	3.2e-01	Click!

Sorted Z-values for motif OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_56270380	1.236	ENST00000434937.2	RFPL4A	ret finger protein-like 4A
chr19_+_56280507	0.536	ENST00000341750.4	RFPL4AL1	ret finger protein-like 4A-like 1
chr11_-_5323226	0.528	ENST00000380224.1	OR51B4	olfactory receptor, family 51, subfamily B, member 4
chr6_+_78400375	0.501	ENST00000602452.2	MEI4	meiosis-specific 4 homolog (S. cerevisiae)
chr20_+_15177480	0.464	ENST00000402914.1	MACROD2	MACRO domain containing 2
chr4_+_183370146	0.453	ENST00000510504.1	TENM3	teneurin transmembrane protein 3
chr1_+_152178320	0.381	ENST00000429352.1	RP11-107M16.2	RP11-107M16.2
chr15_+_48483736	0.352	ENST00000559641.1 ENST00000417307.2	SLC12A1 CTXN2	solute carrier family 12 (sodium/potassium/chloride transporter), member 1 cortexin 2
chrX_+_51486481	0.345	ENST00000340438.4	GSPT2	G1 to S phase transition 2
chr6_-_138833630	0.301	ENST00000533765.1	NHSL1	NHS-like 1
chr7_-_84122033	0.298	ENST00000424555.1	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_157221128	0.292	ENST00000392833.2 ENST00000362010.2	VEPH1	ventricular zone expressed PH domain-containing 1
chr6_+_114178512	0.266	ENST00000368635.4	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr1_-_92952433	0.245	ENST00000294702.5	GFI1	growth factor independent 1 transcription repressor
chr3_-_157221380	0.224	ENST00000468233.1	VEPH1	ventricular zone expressed PH domain-containing 1
chr3_+_111718036	0.218	ENST00000455401.2	TAGLN3	transgelin 3
chr3_+_111717600	0.212	ENST00000273368.4	TAGLN3	transgelin 3
chr3_+_111717511	0.210	ENST00000478951.1 ENST00000393917.2	TAGLN3	transgelin 3
chr12_+_4385230	0.204	ENST00000536537.1	CCND2	cyclin D2
chr3_+_111718173	0.201	ENST00000494932.1	TAGLN3	transgelin 3
chr7_+_134528635	0.186	ENST00000445569.2	CALD1	caldesmon 1
chr3_-_157221357	0.184	ENST00000494677.1	VEPH1	ventricular zone expressed PH domain-containing 1
chr11_+_71934962	0.172	ENST00000543234.1	INPPL1	inositol polyphosphate phosphatase-like 1
chr11_-_327537	0.171	ENST00000602735.1	IFITM3	interferon induced transmembrane protein 3
chr19_-_36001113	0.171	ENST00000434389.1	DMKN	dermokine
chr18_+_47087055	0.166	ENST00000577628.1	LIPG	lipase, endothelial
chr18_+_47087390	0.161	ENST00000583083.1	LIPG	lipase, endothelial
chr5_+_166711804	0.157	ENST00000518659.1 ENST00000545108.1	TENM2	teneurin transmembrane protein 2
chr3_+_138340049	0.148	ENST00000464668.1	FAIM	Fas apoptotic inhibitory molecule
chr16_-_1538765	0.146	ENST00000447419.2 ENST00000440447.2	PTX4	pentraxin 4, long
chr3_-_20053741	0.146	ENST00000389050.4	PP2D1	protein phosphatase 2C-like domain containing 1
chr17_+_56833184	0.134	ENST00000308249.2	PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr15_+_101417919	0.132	ENST00000561338.1	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr6_+_130339710	0.129	ENST00000526087.1 ENST00000533560.1 ENST00000361794.2	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr19_+_54466179	0.126	ENST00000270458.2	CACNG8	calcium channel, voltage-dependent, gamma subunit 8
chr10_+_94451574	0.125	ENST00000492654.2	HHEX	hematopoietically expressed homeobox
chr7_+_150020329	0.120	ENST00000323078.7	LRRC61	leucine rich repeat containing 61
chr2_-_74618907	0.119	ENST00000421392.1 ENST00000437375.1	DCTN1	dynactin 1
chr10_-_50396357	0.118	ENST00000453436.1 ENST00000474718.1	C10orf128	chromosome 10 open reading frame 128
chr10_-_50396407	0.115	ENST00000374153.2 ENST00000374151.3	C10orf128	chromosome 10 open reading frame 128
chr2_-_74618964	0.115	ENST00000417090.1 ENST00000409868.1	DCTN1	dynactin 1
chr10_-_4285923	0.114	ENST00000418372.1 ENST00000608792.1	LINC00702	long intergenic non-protein coding RNA 702
chr17_-_38821373	0.112	ENST00000394052.3	KRT222	keratin 222
chr1_-_231005310	0.110	ENST00000470540.1	C1orf198	chromosome 1 open reading frame 198
chr5_+_66300464	0.109	ENST00000436277.1	MAST4	microtubule associated serine/threonine kinase family member 4
chr12_-_22063787	0.108	ENST00000544039.1	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr7_+_150020363	0.106	ENST00000359623.4 ENST00000493307.1	LRRC61	leucine rich repeat containing 61
chr13_+_46276441	0.105	ENST00000310521.1 ENST00000533564.1	SPERT	spermatid associated
chr6_+_155334780	0.101	ENST00000538270.1 ENST00000535231.1	TIAM2	T-cell lymphoma invasion and metastasis 2
chr21_-_23058648	0.098	ENST00000416182.1	AF241725.6	AF241725.6
chr4_+_183164574	0.096	ENST00000511685.1	TENM3	teneurin transmembrane protein 3
chr2_-_74619152	0.090	ENST00000440727.1 ENST00000409240.1	DCTN1	dynactin 1
chr17_+_1674982	0.087	ENST00000572048.1 ENST00000573763.1	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_-_139047669	0.082	ENST00000370540.1	CXorf66	chromosome X open reading frame 66
chr14_-_80678512	0.082	ENST00000553968.1	DIO2	deiodinase, iodothyronine, type II
chr15_+_64680003	0.082	ENST00000261884.3	TRIP4	thyroid hormone receptor interactor 4
chr17_+_74463650	0.078	ENST00000392492.3	AANAT	aralkylamine N-acetyltransferase
chr13_-_81801115	0.076	ENST00000567258.1	LINC00564	long intergenic non-protein coding RNA 564
chr3_+_157154578	0.075	ENST00000295927.3	PTX3	pentraxin 3, long
chr15_+_54901540	0.074	ENST00000539562.2	UNC13C	unc-13 homolog C (C. elegans)
chr12_+_26348246	0.073	ENST00000422622.2	SSPN	sarcospan
chr12_-_54653313	0.071	ENST00000550411.1 ENST00000439541.2	CBX5	chromobox homolog 5
chr3_+_138340067	0.071	ENST00000479848.1	FAIM	Fas apoptotic inhibitory molecule
chr6_-_133035185	0.068	ENST00000367928.4	VNN1	vanin 1
chr4_+_76481258	0.067	ENST00000311623.4 ENST00000435974.2	C4orf26	chromosome 4 open reading frame 26
chr10_-_99030395	0.066	ENST00000355366.5 ENST00000371027.1	ARHGAP19	Rho GTPase activating protein 19
chr11_+_7618413	0.065	ENST00000528883.1	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr15_-_55489097	0.065	ENST00000260443.4	RSL24D1	ribosomal L24 domain containing 1
chr12_+_26348429	0.064	ENST00000242729.2	SSPN	sarcospan
chrX_+_43515467	0.061	ENST00000338702.3 ENST00000542639.1	MAOA	monoamine oxidase A
chr3_-_157217328	0.060	ENST00000392832.2 ENST00000543418.1	VEPH1	ventricular zone expressed PH domain-containing 1
chr4_+_71108300	0.060	ENST00000304954.3	CSN3	casein kappa
chr17_+_48823896	0.060	ENST00000511974.1	LUC7L3	LUC7-like 3 (S. cerevisiae)
chr3_-_12587055	0.059	ENST00000564146.3	C3orf83	chromosome 3 open reading frame 83
chr17_-_6524159	0.059	ENST00000589033.1	KIAA0753	KIAA0753
chr4_-_186570679	0.058	ENST00000451974.1	SORBS2	sorbin and SH3 domain containing 2
chr3_+_139063372	0.056	ENST00000478464.1	MRPS22	mitochondrial ribosomal protein S22
chr5_-_20575959	0.055	ENST00000507958.1	CDH18	cadherin 18, type 2
chr6_+_4087664	0.053	ENST00000430835.2	C6orf201	chromosome 6 open reading frame 201
chr15_+_75303993	0.052	ENST00000564779.1	SCAMP5	secretory carrier membrane protein 5
chr1_-_114414316	0.052	ENST00000528414.1 ENST00000538253.1 ENST00000460620.1 ENST00000420377.2 ENST00000525799.1 ENST00000359785.5	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr3_-_150421752	0.052	ENST00000498386.1	FAM194A	family with sequence similarity 194, member A
chr17_-_8198636	0.052	ENST00000577745.1 ENST00000579192.1 ENST00000396278.1	SLC25A35	solute carrier family 25, member 35
chr11_-_26744908	0.052	ENST00000533617.1	SLC5A12	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr15_-_75748115	0.051	ENST00000360439.4	SIN3A	SIN3 transcription regulator family member A
chr17_+_57233087	0.050	ENST00000578777.1 ENST00000577457.1 ENST00000582995.1	PRR11	proline rich 11
chr18_-_53177984	0.050	ENST00000543082.1	TCF4	transcription factor 4
chr13_+_103459704	0.049	ENST00000602836.1	BIVM-ERCC5	BIVM-ERCC5 readthrough
chr20_-_56265680	0.049	ENST00000414037.1	PMEPA1	prostate transmembrane protein, androgen induced 1
chr14_-_67878917	0.049	ENST00000216446.4	PLEK2	pleckstrin 2
chr1_+_66820058	0.049	ENST00000480109.2	PDE4B	phosphodiesterase 4B, cAMP-specific
chr18_-_47018869	0.048	ENST00000583036.1 ENST00000580261.1	RPL17	ribosomal protein L17
chr17_-_46688334	0.048	ENST00000239165.7	HOXB7	homeobox B7
chr4_-_185275104	0.047	ENST00000317596.3	RP11-290F5.2	RP11-290F5.2
chr18_-_47018769	0.047	ENST00000583637.1 ENST00000578528.1 ENST00000578532.1 ENST00000580387.1 ENST00000579248.1 ENST00000581373.1	RPL17	ribosomal protein L17
chr3_+_44840679	0.047	ENST00000425755.1	KIF15	kinesin family member 15
chr17_-_72772462	0.047	ENST00000582870.1 ENST00000581136.1 ENST00000357814.3 ENST00000579218.1 ENST00000583476.1 ENST00000580301.1 ENST00000583757.1 ENST00000582524.1	NAT9	N-acetyltransferase 9 (GCN5-related, putative)
chr18_-_47018897	0.046	ENST00000418495.1	RPL17	ribosomal protein L17
chr8_-_104153703	0.043	ENST00000521246.1	C8orf56	chromosome 8 open reading frame 56
chr13_+_77522632	0.043	ENST00000377462.1	IRG1	immunoresponsive 1 homolog (mouse)
chr15_-_75748143	0.043	ENST00000568431.1 ENST00000568309.1 ENST00000568190.1 ENST00000570115.1 ENST00000564778.1	SIN3A	SIN3 transcription regulator family member A
chr3_-_141719195	0.042	ENST00000397991.4	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr10_-_4285835	0.042	ENST00000454470.1	LINC00702	long intergenic non-protein coding RNA 702
chr8_+_104384616	0.040	ENST00000520337.1	CTHRC1	collagen triple helix repeat containing 1
chr2_-_163008903	0.038	ENST00000418842.2 ENST00000375497.3	GCG	glucagon
chr7_-_111032971	0.038	ENST00000450877.1	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_+_114168085	0.036	ENST00000541754.1	NNMT	nicotinamide N-methyltransferase
chr2_+_13677795	0.036	ENST00000434509.1	AC092635.1	AC092635.1
chr3_-_151034734	0.035	ENST00000260843.4	GPR87	G protein-coupled receptor 87
chr1_+_117544366	0.035	ENST00000256652.4 ENST00000369470.1	CD101	CD101 molecule
chrX_-_138724677	0.034	ENST00000370573.4 ENST00000338585.6 ENST00000370576.4	MCF2	MCF.2 cell line derived transforming sequence
chr8_+_39972170	0.034	ENST00000521257.1	RP11-359E19.2	RP11-359E19.2
chr15_+_75970672	0.033	ENST00000435356.1	AC105020.1	Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr10_-_118928543	0.033	ENST00000419373.2	RP11-501J20.2	RP11-501J20.2
chr8_-_49834299	0.033	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr7_+_138145076	0.032	ENST00000343526.4	TRIM24	tripartite motif containing 24
chr3_-_149293990	0.032	ENST00000472417.1	WWTR1	WW domain containing transcription regulator 1
chr1_-_233431458	0.032	ENST00000258229.9 ENST00000430153.1	PCNXL2	pecanex-like 2 (Drosophila)
chr1_+_201617450	0.032	ENST00000295624.6 ENST00000367297.4 ENST00000367300.3	NAV1	neuron navigator 1
chr3_-_141747950	0.032	ENST00000497579.1	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_143599207	0.032	ENST00000355951.2 ENST00000479870.1 ENST00000478172.1	FAM115A	family with sequence similarity 115, member A
chr4_+_113568207	0.032	ENST00000511529.1	LARP7	La ribonucleoprotein domain family, member 7
chr15_-_88247083	0.031	ENST00000560439.1	RP11-648K4.2	RP11-648K4.2
chr2_+_234826016	0.031	ENST00000324695.4 ENST00000433712.2	TRPM8	transient receptor potential cation channel, subfamily M, member 8
chr8_-_49833978	0.031	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr4_+_71019903	0.030	ENST00000344526.5	C4orf40	chromosome 4 open reading frame 40
chr17_+_48823975	0.030	ENST00000513969.1 ENST00000503728.1	LUC7L3	LUC7-like 3 (S. cerevisiae)
chr20_-_50418947	0.030	ENST00000371539.3	SALL4	spalt-like transcription factor 4
chr12_-_118796971	0.030	ENST00000542902.1	TAOK3	TAO kinase 3
chr3_-_99569821	0.030	ENST00000487087.1	FILIP1L	filamin A interacting protein 1-like
chr1_+_201617264	0.030	ENST00000367296.4	NAV1	neuron navigator 1
chr7_-_22862406	0.029	ENST00000372879.4	TOMM7	translocase of outer mitochondrial membrane 7 homolog (yeast)
chr17_-_72772425	0.029	ENST00000578822.1	NAT9	N-acetyltransferase 9 (GCN5-related, putative)
chr12_+_20963632	0.028	ENST00000540853.1 ENST00000261196.2	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr12_-_95510743	0.028	ENST00000551521.1	FGD6	FYVE, RhoGEF and PH domain containing 6
chr1_+_160370344	0.028	ENST00000368061.2	VANGL2	VANGL planar cell polarity protein 2
chr9_-_99540328	0.028	ENST00000223428.4 ENST00000375231.1 ENST00000374641.3	ZNF510	zinc finger protein 510
chr5_+_66300446	0.028	ENST00000261569.7	MAST4	microtubule associated serine/threonine kinase family member 4
chr7_-_5465045	0.028	ENST00000399434.2	TNRC18	trinucleotide repeat containing 18
chr4_-_122854612	0.027	ENST00000264811.5	TRPC3	transient receptor potential cation channel, subfamily C, member 3
chr1_+_146714291	0.027	ENST00000431239.1 ENST00000369259.3 ENST00000369258.4 ENST00000361293.5	CHD1L	chromodomain helicase DNA binding protein 1-like
chr1_+_78769549	0.027	ENST00000370758.1	PTGFR	prostaglandin F receptor (FP)
chr1_-_39339777	0.027	ENST00000397572.2	MYCBP	MYC binding protein
chr20_+_31870927	0.026	ENST00000253354.1	BPIFB1	BPI fold containing family B, member 1
chr17_-_16256718	0.026	ENST00000476243.1 ENST00000299736.4	CENPV	centromere protein V
chr19_+_23945768	0.026	ENST00000486528.1 ENST00000496398.1	RPSAP58	ribosomal protein SA pseudogene 58
chr5_+_36606700	0.026	ENST00000416645.2	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_176889381	0.026	ENST00000393563.4 ENST00000512501.1	DBN1	drebrin 1
chr7_+_141811539	0.025	ENST00000550469.2 ENST00000477922.3	RP11-1220K2.2	Putative inactive maltase-glucoamylase-like protein LOC93432
chr11_-_8857248	0.025	ENST00000534248.1 ENST00000530959.1 ENST00000531578.1 ENST00000533225.1	ST5	suppression of tumorigenicity 5
chr6_+_3259122	0.024	ENST00000438998.2 ENST00000380305.4	PSMG4	proteasome (prosome, macropain) assembly chaperone 4
chr6_+_3259148	0.024	ENST00000419065.2 ENST00000473000.2 ENST00000451246.2 ENST00000454610.2	PSMG4	proteasome (prosome, macropain) assembly chaperone 4
chr1_+_225600404	0.024	ENST00000366845.2	AC092811.1	AC092811.1
chr1_+_109265033	0.024	ENST00000445274.1	FNDC7	fibronectin type III domain containing 7
chr3_-_122233723	0.024	ENST00000493510.1 ENST00000344337.6 ENST00000476916.1 ENST00000465882.1	KPNA1	karyopherin alpha 1 (importin alpha 5)
chr18_+_56806701	0.023	ENST00000587834.1	SEC11C	SEC11 homolog C (S. cerevisiae)
chrX_-_77225135	0.023	ENST00000458128.1	PGAM4	phosphoglycerate mutase family member 4
chrX_-_71458802	0.022	ENST00000373657.1 ENST00000334463.3	ERCC6L	excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr8_-_90996459	0.022	ENST00000517337.1 ENST00000409330.1	NBN	nibrin
chr4_-_170948361	0.022	ENST00000393702.3	MFAP3L	microfibrillar-associated protein 3-like
chr12_-_118796910	0.022	ENST00000541186.1 ENST00000539872.1	TAOK3	TAO kinase 3
chr3_-_33686925	0.022	ENST00000485378.2 ENST00000313350.6 ENST00000487200.1	CLASP2	cytoplasmic linker associated protein 2
chr12_+_104337515	0.022	ENST00000550595.1	HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
chr6_-_109702885	0.022	ENST00000504373.1	CD164	CD164 molecule, sialomucin
chr9_+_71986182	0.021	ENST00000303068.7	FAM189A2	family with sequence similarity 189, member A2
chr9_-_77567743	0.021	ENST00000376854.5	C9orf40	chromosome 9 open reading frame 40
chrX_+_56100757	0.021	ENST00000433279.1	AL353698.1	Uncharacterized protein
chr18_-_52989217	0.021	ENST00000570287.2	TCF4	transcription factor 4
chrX_-_138724994	0.021	ENST00000536274.1	MCF2	MCF.2 cell line derived transforming sequence
chr11_-_107729504	0.021	ENST00000265836.7	SLC35F2	solute carrier family 35, member F2
chr12_-_25348007	0.021	ENST00000354189.5 ENST00000545133.1 ENST00000554347.1 ENST00000395987.3 ENST00000320267.9 ENST00000395990.2 ENST00000537577.1	CASC1	cancer susceptibility candidate 1
chr10_-_75415825	0.021	ENST00000394810.2	SYNPO2L	synaptopodin 2-like
chr15_+_93443419	0.020	ENST00000557381.1 ENST00000420239.2	CHD2	chromodomain helicase DNA binding protein 2
chr1_-_39347255	0.020	ENST00000454994.2 ENST00000357771.3	GJA9	gap junction protein, alpha 9, 59kDa
chr3_-_114477787	0.020	ENST00000464560.1	ZBTB20	zinc finger and BTB domain containing 20
chr7_-_87856280	0.020	ENST00000490437.1 ENST00000431660.1	SRI	sorcin
chr18_-_52989525	0.020	ENST00000457482.3	TCF4	transcription factor 4
chr7_-_87856303	0.019	ENST00000394641.3	SRI	sorcin
chr20_-_50419055	0.019	ENST00000217086.4	SALL4	spalt-like transcription factor 4
chr21_-_27423339	0.019	ENST00000415997.1	APP	amyloid beta (A4) precursor protein
chr6_+_125304502	0.019	ENST00000519799.1 ENST00000368414.2 ENST00000359704.2	RNF217	ring finger protein 217
chr16_+_31271274	0.019	ENST00000287497.8 ENST00000544665.3	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)
chr5_+_179135246	0.018	ENST00000508787.1	CANX	calnexin
chr7_+_73868439	0.018	ENST00000424337.2	GTF2IRD1	GTF2I repeat domain containing 1
chr7_-_22862448	0.018	ENST00000358435.4	TOMM7	translocase of outer mitochondrial membrane 7 homolog (yeast)
chr9_+_34652164	0.018	ENST00000441545.2 ENST00000553620.1	IL11RA	interleukin 11 receptor, alpha
chr3_-_149095652	0.018	ENST00000305366.3	TM4SF1	transmembrane 4 L six family member 1
chr15_-_37393406	0.018	ENST00000338564.5 ENST00000558313.1 ENST00000340545.5	MEIS2	Meis homeobox 2
chr12_+_122688090	0.018	ENST00000324189.4 ENST00000546192.1	B3GNT4	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr6_-_116833500	0.018	ENST00000356128.4	TRAPPC3L	trafficking protein particle complex 3-like
chr12_+_78359999	0.017	ENST00000550503.1	NAV3	neuron navigator 3
chr3_+_23851928	0.017	ENST00000467766.1 ENST00000424381.1	UBE2E1	ubiquitin-conjugating enzyme E2E 1
chr3_-_114477962	0.017	ENST00000471418.1	ZBTB20	zinc finger and BTB domain containing 20
chr5_+_96840389	0.016	ENST00000504012.1	RP11-1E3.1	RP11-1E3.1
chr7_-_102283238	0.016	ENST00000340457.8	UPK3BL	uroplakin 3B-like
chr12_-_112123524	0.016	ENST00000327551.6	BRAP	BRCA1 associated protein
chr1_-_197115818	0.016	ENST00000367409.4 ENST00000294732.7	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr12_-_15114191	0.016	ENST00000541380.1	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr11_+_6220376	0.016	ENST00000311352.2	OR52W1	olfactory receptor, family 52, subfamily W, member 1
chr16_-_66583994	0.016	ENST00000564917.1	TK2	thymidine kinase 2, mitochondrial

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.1	0.3	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.1	0.3	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1	0.2	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	0.3	GO:1903045	neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1	0.5	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.1	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.0	0.3	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.7	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:1903575	cornified envelope assembly(GO:1903575)
0.0	0.1	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0	0.3	GO:0097475	motor neuron migration(GO:0097475)
0.0	0.1	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.1	GO:1902523	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.0	GO:0061300	cerebellum vasculature development(GO:0061300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0018444	translation release factor complex(GO:0018444)
0.1	0.3	GO:0042585	female germ cell nucleus(GO:0001674) germinal vesicle(GO:0042585)
0.0	0.2	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.5	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.0	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.0	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.0	GO:0005873	plus-end kinesin complex(GO:0005873)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.0	0.3	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.0	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.2	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion