Motif ID: ONECUT1

Z-value: 0.502


Transcription factors associated with ONECUT1:

Gene SymbolEntrez IDGene Name
ONECUT1 ENSG00000169856.7 ONECUT1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ONECUT1hg19_v2_chr15_-_53082178_530822090.265.1e-01Click!


Activity profile for motif ONECUT1.

activity profile for motif ONECUT1


Sorted Z-values histogram for motif ONECUT1

Sorted Z-values for motif ONECUT1



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_207262578 1.046 ENST00000243611.5
ENST00000367076.3
C4BPB

complement component 4 binding protein, beta

chr1_+_207262540 0.885 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr7_-_121944491 0.834 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr1_+_207262627 0.819 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr7_-_81635106 0.644 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr10_+_70980051 0.584 ENST00000354624.5
ENST00000395086.2
HKDC1

hexokinase domain containing 1

chr9_-_14180778 0.368 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr16_-_65106110 0.345 ENST00000562882.1
ENST00000567934.1
CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

chr6_+_116782527 0.334 ENST00000368606.3
ENST00000368605.1
FAM26F

family with sequence similarity 26, member F

chr10_+_28966271 0.327 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr9_-_114521783 0.282 ENST00000394779.3
ENST00000394777.4
C9orf84

chromosome 9 open reading frame 84

chr4_+_110834033 0.281 ENST00000509793.1
ENST00000265171.5
EGF

epidermal growth factor

chr11_+_102188272 0.280 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr10_-_53459319 0.268 ENST00000331173.4
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr5_-_90679145 0.264 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr2_-_172967621 0.237 ENST00000234198.4
ENST00000466293.2
DLX2

distal-less homeobox 2

chr17_-_26697304 0.229 ENST00000536498.1
VTN
vitronectin
chr3_-_24207039 0.228 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr8_-_27468842 0.223 ENST00000523500.1
CLU
clusterin
chr1_+_207262881 0.219 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr7_+_141463897 0.218 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr4_-_168155169 0.210 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_-_154167124 0.209 ENST00000515609.1
TPM3
tropomyosin 3
chr12_-_95941987 0.205 ENST00000537435.2
USP44
ubiquitin specific peptidase 44
chr8_-_27468717 0.203 ENST00000520796.1
ENST00000520491.1
CLU

clusterin

chrX_-_151143140 0.197 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
GABRE


gamma-aminobutyric acid (GABA) A receptor, epsilon


chr7_-_115670792 0.193 ENST00000265440.7
ENST00000393485.1
TFEC

transcription factor EC

chr3_-_112693759 0.180 ENST00000440122.2
ENST00000490004.1
CD200R1

CD200 receptor 1

chr6_+_27925019 0.179 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chrX_+_10124977 0.173 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr12_-_72104152 0.169 ENST00000549710.1
RP11-498M15.1
RP11-498M15.1
chr11_-_1780261 0.167 ENST00000427721.1
RP11-295K3.1
RP11-295K3.1
chr4_+_71091786 0.165 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr3_+_69812877 0.161 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr12_+_56623827 0.157 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
SLC39A5




solute carrier family 39 (zinc transporter), member 5




chr11_+_62623621 0.156 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr16_-_19896220 0.156 ENST00000562469.1
ENST00000300571.2
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr3_+_181429704 0.155 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr11_+_62623544 0.154 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2


solute carrier family 3 (amino acid transporter heavy chain), member 2


chr2_-_192016276 0.154 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr5_-_115910630 0.145 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_-_214016314 0.144 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr1_-_8075693 0.142 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr2_+_241375069 0.142 ENST00000264039.2
GPC1
glypican 1
chr12_-_53297432 0.140 ENST00000546900.1
KRT8
keratin 8
chr1_+_10292308 0.140 ENST00000377081.1
KIF1B
kinesin family member 1B
chr20_-_22566089 0.140 ENST00000377115.4
FOXA2
forkhead box A2
chr10_-_28032421 0.137 ENST00000460919.2
MKX
mohawk homeobox
chr12_+_70760056 0.136 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr19_+_37997812 0.133 ENST00000542455.1
ENST00000587143.1
ZNF793

zinc finger protein 793

chr3_+_142315294 0.130 ENST00000464320.1
PLS1
plastin 1
chr4_+_78078304 0.128 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr11_+_57365150 0.127 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr3_-_112693865 0.125 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1


CD200 receptor 1


chr10_-_5227096 0.124 ENST00000488756.1
ENST00000334314.3
AKR1CL1

aldo-keto reductase family 1, member C-like 1

chr9_-_77703115 0.121 ENST00000361092.4
ENST00000376808.4
NMRK1

nicotinamide riboside kinase 1

chr3_+_142315225 0.118 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chrX_+_49126294 0.118 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F



protein phosphatase 1, regulatory subunit 3F



chr1_-_186649543 0.116 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_145028013 0.115 ENST00000354958.2
PLEC
plectin
chr21_-_43735628 0.114 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr12_-_13529594 0.112 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr7_-_115670804 0.112 ENST00000320239.7
TFEC
transcription factor EC
chr12_-_10978957 0.110 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr4_+_79475019 0.109 ENST00000508214.1
ANXA3
annexin A3
chr14_+_74083548 0.109 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr9_-_77703056 0.106 ENST00000376811.1
NMRK1
nicotinamide riboside kinase 1
chr11_+_107650219 0.104 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr7_-_142149390 0.104 ENST00000390372.3
TRBV5-5
T cell receptor beta variable 5-5
chr2_+_157330081 0.103 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr3_+_177545563 0.102 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr3_+_32280159 0.102 ENST00000458535.2
ENST00000307526.3
CMTM8

CKLF-like MARVEL transmembrane domain containing 8

chr8_+_120885949 0.095 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr1_-_202679535 0.093 ENST00000367268.4
SYT2
synaptotagmin II
chr4_+_147145709 0.092 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr4_+_76649753 0.091 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr11_-_19223523 0.091 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr4_-_175443484 0.091 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD




hydroxyprostaglandin dehydrogenase 15-(NAD)




chrX_+_27608490 0.091 ENST00000451261.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr9_+_67977438 0.090 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr13_-_107187462 0.089 ENST00000245323.4
EFNB2
ephrin-B2
chr12_+_56624436 0.089 ENST00000266980.4
ENST00000437277.1
SLC39A5

solute carrier family 39 (zinc transporter), member 5

chr14_+_38033252 0.088 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr5_+_115358088 0.087 ENST00000600981.3
CTD-2287O16.3
CTD-2287O16.3
chr12_+_74931551 0.086 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr6_+_126221034 0.085 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr21_+_17961006 0.084 ENST00000602323.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_58864848 0.084 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr15_+_48051920 0.082 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr16_-_18573396 0.082 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NOMO2


NODAL modulator 2


chr21_+_42792442 0.081 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_+_212738676 0.081 ENST00000366981.4
ENST00000366987.2
ATF3

activating transcription factor 3

chr12_+_21679220 0.081 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr17_-_26733604 0.079 ENST00000584426.1
ENST00000584995.1
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr17_-_72619869 0.079 ENST00000392619.1
ENST00000426295.2
CD300E

CD300e molecule

chr20_-_22559211 0.076 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr5_+_140165876 0.075 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr19_+_33865218 0.075 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr4_+_76649797 0.074 ENST00000538159.1
ENST00000514213.2
USO1

USO1 vesicle transport factor

chr2_-_161349909 0.073 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_+_26496362 0.072 ENST00000374266.5
ENST00000270812.5
ZNF593

zinc finger protein 593

chr9_+_84603687 0.068 ENST00000344803.2
SPATA31D1
SPATA31 subfamily D, member 1
chr12_-_11062161 0.067 ENST00000390677.2
TAS2R13
taste receptor, type 2, member 13
chr12_-_13529642 0.065 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr2_-_161350305 0.063 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_+_98699880 0.062 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr19_+_45596398 0.061 ENST00000544069.2
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr1_+_113933371 0.061 ENST00000369617.4
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr17_-_79876010 0.061 ENST00000328666.6
SIRT7
sirtuin 7
chr9_-_116840728 0.061 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr5_+_98109322 0.060 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr12_-_90024360 0.060 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr19_+_45596218 0.059 ENST00000421905.1
ENST00000221462.4
PPP1R37

protein phosphatase 1, regulatory subunit 37

chr7_-_132261253 0.059 ENST00000321063.4
PLXNA4
plexin A4
chr19_+_2785458 0.058 ENST00000307741.6
ENST00000585338.1
THOP1

thimet oligopeptidase 1

chr2_-_55646412 0.058 ENST00000413716.2
CCDC88A
coiled-coil domain containing 88A
chr5_-_130868688 0.057 ENST00000504575.1
ENST00000513227.1
RAPGEF6

Rap guanine nucleotide exchange factor (GEF) 6

chr1_+_78245303 0.057 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr19_-_19729725 0.056 ENST00000251203.9
PBX4
pre-B-cell leukemia homeobox 4
chr16_+_16326352 0.055 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NOMO3


NODAL modulator 3


chr8_-_33370607 0.055 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr4_-_111563279 0.055 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr2_-_214017151 0.055 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr10_-_94003003 0.055 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr4_-_48683188 0.054 ENST00000505759.1
FRYL
FRY-like
chr4_+_169418195 0.053 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr11_-_118305921 0.053 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr1_+_152178320 0.052 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr7_-_152373216 0.052 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr12_+_69742121 0.050 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ


lysozyme


chrX_+_135388147 0.049 ENST00000394141.1
GPR112
G protein-coupled receptor 112
chr11_-_105948040 0.049 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr1_+_17575584 0.048 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr5_+_119799927 0.046 ENST00000407149.2
ENST00000379551.2
PRR16

proline rich 16

chrX_-_16887963 0.046 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr17_-_64225508 0.045 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_113933581 0.045 ENST00000307546.9
ENST00000369615.1
ENST00000369611.4
MAGI3


membrane associated guanylate kinase, WW and PDZ domain containing 3


chr2_+_149804382 0.044 ENST00000397413.1
KIF5C
kinesin family member 5C
chr22_-_37505588 0.043 ENST00000406856.1
TMPRSS6
transmembrane protease, serine 6
chr2_+_78143006 0.043 ENST00000443419.1
AC073628.1
AC073628.1
chr6_-_154568815 0.043 ENST00000519344.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr6_-_133055815 0.041 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3






vanin 3






chr4_-_17513604 0.041 ENST00000505710.1
QDPR
quinoid dihydropteridine reductase
chr12_+_8995832 0.040 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr3_-_191000172 0.039 ENST00000427544.2
UTS2B
urotensin 2B
chr15_-_74421477 0.039 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr10_+_105881906 0.039 ENST00000369727.3
ENST00000336358.5
SFR1

SWI5-dependent recombination repair 1

chr7_+_97736197 0.038 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chrX_-_33229429 0.038 ENST00000420596.1
ENST00000448370.1
DMD

dystrophin

chr14_-_27066960 0.038 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr14_+_62585332 0.038 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr11_+_47279155 0.037 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3


nuclear receptor subfamily 1, group H, member 3


chr1_-_94586651 0.037 ENST00000535735.1
ENST00000370225.3
ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr1_-_116383738 0.037 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr22_-_36220420 0.037 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_-_151330218 0.036 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr18_-_24765248 0.036 ENST00000580774.1
ENST00000284224.8
CHST9

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9

chr16_+_31044413 0.035 ENST00000394998.1
STX4
syntaxin 4
chr4_-_111563076 0.034 ENST00000354925.2
ENST00000511990.1
PITX2

paired-like homeodomain 2

chr14_+_101299520 0.034 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr10_+_105881779 0.034 ENST00000369729.3
SFR1
SWI5-dependent recombination repair 1
chr15_-_47426320 0.033 ENST00000557832.1
FKSG62
FKSG62
chr2_-_214148921 0.033 ENST00000360083.3
AC079610.2
AC079610.2
chr1_-_1590418 0.033 ENST00000341028.7
CDK11B
cyclin-dependent kinase 11B
chr22_-_37505449 0.033 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr4_+_169418255 0.032 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr4_+_123073464 0.031 ENST00000264501.4
KIAA1109
KIAA1109
chr22_-_26961328 0.031 ENST00000398110.2
TPST2
tyrosylprotein sulfotransferase 2
chr4_+_159727272 0.031 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr8_-_23712312 0.031 ENST00000290271.2
STC1
stanniocalcin 1
chr11_-_122931881 0.030 ENST00000526110.1
ENST00000227378.3
HSPA8

heat shock 70kDa protein 8

chrX_+_54466829 0.030 ENST00000375151.4
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr4_+_159131596 0.029 ENST00000512481.1
TMEM144
transmembrane protein 144
chr6_-_27799305 0.029 ENST00000357549.2
HIST1H4K
histone cluster 1, H4k
chr2_-_220117867 0.028 ENST00000456818.1
ENST00000447205.1
TUBA4A

tubulin, alpha 4a

chr1_-_26633067 0.027 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11








UBX domain protein 11








chr16_-_29499154 0.027 ENST00000354563.5
RP11-231C14.4
Uncharacterized protein
chr11_+_118938485 0.026 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr11_+_85359002 0.026 ENST00000528105.1
ENST00000304511.2
TMEM126A

transmembrane protein 126A

chr17_+_73539339 0.026 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr3_+_107364769 0.025 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX


bobby sox homolog (Drosophila)


chr1_+_110546700 0.025 ENST00000359172.3
ENST00000393614.4
AHCYL1

adenosylhomocysteinase-like 1

chr3_-_170744498 0.024 ENST00000382808.4
ENST00000314251.3
SLC2A2

solute carrier family 2 (facilitated glucose transporter), member 2

chr5_+_167956121 0.023 ENST00000338333.4
FBLL1
fibrillarin-like 1
chr7_-_78400598 0.023 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_133174147 0.023 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chr1_-_1655713 0.023 ENST00000401096.2
ENST00000404249.3
ENST00000357760.2
ENST00000358779.5
ENST00000378633.1
ENST00000378635.3
CDK11A





cyclin-dependent kinase 11A





chr3_+_107364683 0.022 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr21_-_43816152 0.022 ENST00000433957.2
ENST00000398397.3
TMPRSS3

transmembrane protease, serine 3

chr4_+_159131630 0.022 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144



transmembrane protein 144



chr15_-_38519066 0.021 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1

RP11-346D14.1

chr12_+_43086018 0.021 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr4_-_103747011 0.021 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr21_-_43816052 0.021 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr11_-_122930121 0.021 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr4_-_103746924 0.021 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3


ubiquitin-conjugating enzyme E2D 3


chr1_+_159557607 0.021 ENST00000255040.2
APCS
amyloid P component, serum
chr19_-_48016023 0.020 ENST00000598615.1
ENST00000597118.1
NAPA

N-ethylmaleimide-sensitive factor attachment protein, alpha

chr1_-_165414414 0.020 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr12_-_96336369 0.020 ENST00000546947.1
ENST00000546386.1
CCDC38

coiled-coil domain containing 38


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.2 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of fibroblast growth factor production(GO:0090271) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.6 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.1 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 3.0 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.6 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination