Motif ID: NR5A2

Z-value: 1.017


Transcription factors associated with NR5A2:

Gene SymbolEntrez IDGene Name
NR5A2 ENSG00000116833.9 NR5A2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v2_chr1_+_200011711_200011752-0.521.5e-01Click!


Activity profile for motif NR5A2.

activity profile for motif NR5A2


Sorted Z-values histogram for motif NR5A2

Sorted Z-values for motif NR5A2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_54281491 3.107 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr5_-_54281407 3.032 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr3_-_121379739 2.143 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr2_-_31361543 1.764 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr2_+_220491973 1.677 ENST00000358055.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr9_-_117568365 1.579 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr18_-_56296182 1.518 ENST00000361673.3
ALPK2
alpha-kinase 2
chr6_+_43968306 1.513 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr19_-_51220176 1.443 ENST00000359082.3
ENST00000293441.1
SHANK1

SH3 and multiple ankyrin repeat domains 1

chr19_-_51192661 1.340 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr17_+_74536115 1.322 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr2_-_31361362 1.301 ENST00000430167.1
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_39826639 1.279 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr2_+_220492116 1.088 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr11_-_65640198 1.058 ENST00000528176.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr11_-_65640325 1.050 ENST00000307998.6
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr11_-_65640071 1.025 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr1_-_200992827 1.023 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr20_+_1875942 0.969 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr15_+_59730348 0.966 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chr1_+_16083154 0.908 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr22_+_31518938 0.903 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr3_-_156840776 0.889 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr19_-_55669093 0.859 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr12_+_49740700 0.843 ENST00000549441.2
ENST00000395069.3
DNAJC22

DnaJ (Hsp40) homolog, subfamily C, member 22

chr4_-_74864386 0.843 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_+_203096831 0.830 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr15_-_74659978 0.819 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1


cytochrome P450, family 11, subfamily A, polypeptide 1


chr14_+_52327109 0.801 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr19_+_589893 0.795 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_-_124767693 0.779 ENST00000533054.1
ROBO4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr15_+_89584447 0.767 ENST00000565938.1
RP11-326A19.4
RP11-326A19.4
chr21_+_47063590 0.750 ENST00000400314.1
PCBP3
poly(rC) binding protein 3
chr12_+_54384370 0.738 ENST00000504315.1
HOXC6
homeobox C6
chr1_+_16083123 0.733 ENST00000510393.1
ENST00000430076.1
FBLIM1

filamin binding LIM protein 1

chr17_+_74536164 0.724 ENST00000586148.1
PRCD
progressive rod-cone degeneration
chr22_+_21321531 0.699 ENST00000405089.1
ENST00000335375.5
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr12_+_52056548 0.645 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr16_+_58535372 0.630 ENST00000566656.1
ENST00000566618.1
NDRG4

NDRG family member 4

chr1_+_16083098 0.615 ENST00000496928.2
ENST00000508310.1
FBLIM1

filamin binding LIM protein 1

chr20_-_44333658 0.610 ENST00000330523.5
ENST00000335769.2
WFDC10B

WAP four-disulfide core domain 10B

chr2_+_220492287 0.590 ENST00000273063.6
ENST00000373762.3
SLC4A3

solute carrier family 4 (anion exchanger), member 3

chr10_+_118187379 0.587 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr2_+_220492373 0.570 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr12_-_111358372 0.560 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr17_-_46682321 0.556 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr20_-_36889127 0.541 ENST00000279024.4
KIAA1755
KIAA1755
chr10_+_88414338 0.535 ENST00000241891.5
ENST00000443292.1
OPN4

opsin 4

chr13_+_100634004 0.524 ENST00000376335.3
ZIC2
Zic family member 2
chr15_+_83776137 0.514 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr16_+_31366536 0.506 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr22_+_21321447 0.500 ENST00000434714.1
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr3_-_55523966 0.500 ENST00000474267.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr1_+_202995611 0.495 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr16_-_12897642 0.493 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1


calcineurin-like phosphoesterase domain containing 1


chr2_-_74374995 0.484 ENST00000295326.4
BOLA3
bolA family member 3
chr11_+_10472223 0.477 ENST00000396554.3
ENST00000524866.1
AMPD3

adenosine monophosphate deaminase 3

chr7_+_128355439 0.476 ENST00000315184.5
FAM71F1
family with sequence similarity 71, member F1
chr19_+_50191921 0.476 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chrX_-_124097620 0.472 ENST00000371130.3
ENST00000422452.2
TENM1

teneurin transmembrane protein 1

chr1_-_146696901 0.470 ENST00000369272.3
ENST00000441068.2
FMO5

flavin containing monooxygenase 5

chr14_-_25479811 0.469 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr7_+_100318423 0.468 ENST00000252723.2
EPO
erythropoietin
chr22_-_39637135 0.467 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr3_+_54156664 0.466 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr2_-_73511407 0.464 ENST00000520530.2
FBXO41
F-box protein 41
chr22_+_45072925 0.463 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr16_-_58328923 0.461 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54


protease, serine, 54


chr1_-_48866517 0.454 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr11_-_65793948 0.445 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr10_+_88414298 0.440 ENST00000372071.2
OPN4
opsin 4
chr17_+_74372662 0.437 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr11_+_7618413 0.435 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_21911054 0.420 ENST00000519850.1
ENST00000381470.3
DMTN

dematin actin binding protein

chr22_+_23412479 0.419 ENST00000248996.4
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr22_-_39636914 0.405 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr16_+_8814563 0.405 ENST00000425191.2
ENST00000569156.1
ABAT

4-aminobutyrate aminotransferase

chr6_+_134758827 0.399 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr15_+_63335899 0.398 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr3_+_102153859 0.398 ENST00000306176.1
ENST00000466937.1
ZPLD1

zona pellucida-like domain containing 1

chr22_-_44708731 0.394 ENST00000381176.4
KIAA1644
KIAA1644
chr5_+_149569520 0.385 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr16_-_58328870 0.376 ENST00000543437.1
PRSS54
protease, serine, 54
chr22_-_29711704 0.371 ENST00000216101.6
RASL10A
RAS-like, family 10, member A
chr11_-_33913708 0.367 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr22_+_42372764 0.367 ENST00000396426.3
ENST00000406029.1
SEPT3

septin 3

chr6_-_131299929 0.366 ENST00000531356.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_+_156830678 0.358 ENST00000524377.1
ENST00000358660.3
NTRK1

neurotrophic tyrosine kinase, receptor, type 1

chr13_+_113622757 0.357 ENST00000375604.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_-_30960876 0.356 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1


galactose-3-O-sulfotransferase 1


chr22_+_19710468 0.353 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr22_+_38382163 0.352 ENST00000333418.4
ENST00000427034.1
POLR2F

polymerase (RNA) II (DNA directed) polypeptide F

chr13_+_47127293 0.351 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr13_+_47127322 0.350 ENST00000389798.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr6_-_131321863 0.350 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr13_-_99174252 0.347 ENST00000376547.3
STK24
serine/threonine kinase 24
chr13_+_100258907 0.345 ENST00000376355.3
ENST00000376360.1
ENST00000444838.2
ENST00000376354.1
ENST00000339105.4
CLYBL




citrate lyase beta like




chr11_+_7597639 0.345 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_+_16926441 0.342 ENST00000418129.2
ENST00000396755.2
PLCL2

phospholipase C-like 2

chr3_+_54156570 0.338 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr15_-_83621435 0.336 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2



homer homolog 2 (Drosophila)



chr5_+_74632993 0.336 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr7_-_150329421 0.335 ENST00000493969.1
ENST00000328902.5
GIMAP6

GTPase, IMAP family member 6

chr22_-_29711645 0.335 ENST00000401450.3
RASL10A
RAS-like, family 10, member A
chr1_+_120049826 0.333 ENST00000369413.3
ENST00000235547.6
ENST00000528909.1
HSD3B1


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1


chr2_-_237416071 0.333 ENST00000309507.5
ENST00000431676.2
IQCA1

IQ motif containing with AAA domain 1

chr5_+_74633036 0.333 ENST00000343975.5
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr13_+_47127395 0.332 ENST00000389797.3
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr7_+_56032652 0.330 ENST00000437587.1
GBAS
glioblastoma amplified sequence
chr17_+_34058639 0.327 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr21_+_42539701 0.322 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2


beta-site APP-cleaving enzyme 2


chr11_+_1411503 0.321 ENST00000526678.1
BRSK2
BR serine/threonine kinase 2
chr21_+_44073860 0.321 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A











phosphodiesterase 9A











chr7_+_56032270 0.320 ENST00000322090.3
ENST00000446778.1
GBAS

glioblastoma amplified sequence

chr9_+_126131131 0.320 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr1_-_202129704 0.318 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7








protein tyrosine phosphatase, non-receptor type 7








chr21_+_39644395 0.316 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_133493200 0.313 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr10_-_88729200 0.311 ENST00000474994.2
MMRN2
multimerin 2
chr2_+_204571375 0.311 ENST00000374478.4
CD28
CD28 molecule
chr22_+_37959647 0.311 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr1_+_55464600 0.310 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr13_+_113622810 0.310 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr18_-_56985873 0.308 ENST00000299721.3
CPLX4
complexin 4
chr17_-_17485731 0.307 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr11_+_7598239 0.306 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_-_3767506 0.306 ENST00000538171.1
TRAP1
TNF receptor-associated protein 1
chr9_+_133978190 0.305 ENST00000372312.3
AIF1L
allograft inflammatory factor 1-like
chr21_+_39644305 0.305 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr15_-_81616446 0.302 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr1_-_146697185 0.302 ENST00000533174.1
ENST00000254090.4
FMO5

flavin containing monooxygenase 5

chr13_-_30160925 0.300 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr13_-_46679185 0.298 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr2_+_11817713 0.297 ENST00000449576.2
LPIN1
lipin 1
chr21_+_39644172 0.296 ENST00000398932.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_+_120189422 0.295 ENST00000306406.4
TMEM37
transmembrane protein 37
chr19_-_39108643 0.294 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr1_+_159770292 0.293 ENST00000536257.1
ENST00000321935.6
FCRL6

Fc receptor-like 6

chr4_+_74735102 0.293 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_+_120049809 0.293 ENST00000531340.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr2_+_88991162 0.292 ENST00000283646.4
RPIA
ribose 5-phosphate isomerase A
chr15_+_93426514 0.290 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr16_-_3767551 0.290 ENST00000246957.5
TRAP1
TNF receptor-associated protein 1
chr7_-_38389573 0.290 ENST00000390344.2
TRGV5
T cell receptor gamma variable 5
chr12_+_121416489 0.289 ENST00000541395.1
ENST00000544413.1
HNF1A

HNF1 homeobox A

chr1_+_156830607 0.286 ENST00000368196.3
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr17_+_48585902 0.286 ENST00000452039.1
MYCBPAP
MYCBP associated protein
chr10_+_104180580 0.286 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr3_+_155588375 0.285 ENST00000295920.7
GMPS
guanine monphosphate synthase
chr8_-_145550337 0.283 ENST00000531896.1
DGAT1
diacylglycerol O-acyltransferase 1
chr15_+_68117872 0.282 ENST00000380035.2
ENST00000389002.1
SKOR1

SKI family transcriptional corepressor 1

chr4_-_142053952 0.280 ENST00000515673.2
RNF150
ring finger protein 150
chr12_+_120875910 0.276 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr9_+_134165195 0.274 ENST00000372261.1
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr17_-_46608272 0.273 ENST00000577092.1
ENST00000239174.6
HOXB1

homeobox B1

chr11_+_86667117 0.270 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr12_-_12491608 0.269 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr17_-_7080801 0.266 ENST00000572879.1
ASGR1
asialoglycoprotein receptor 1
chr5_+_34757309 0.266 ENST00000397449.1
RAI14
retinoic acid induced 14
chr12_-_49393092 0.265 ENST00000421952.2
DDN
dendrin
chr19_-_50311896 0.262 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr12_-_120765565 0.260 ENST00000423423.3
ENST00000308366.4
PLA2G1B

phospholipase A2, group IB (pancreas)

chr11_-_61348292 0.258 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
SYT7





synaptotagmin VII





chr3_+_113609472 0.257 ENST00000472026.1
ENST00000462838.1
GRAMD1C

GRAM domain containing 1C

chr15_+_78857870 0.257 ENST00000559554.1
CHRNA5
cholinergic receptor, nicotinic, alpha 5 (neuronal)
chr11_+_73498973 0.254 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr19_-_17356697 0.253 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr19_-_49552006 0.253 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr1_+_45478568 0.252 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr4_-_186734275 0.251 ENST00000456060.1
SORBS2
sorbin and SH3 domain containing 2
chr18_+_50278430 0.251 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC


deleted in colorectal carcinoma


chr15_-_62007370 0.251 ENST00000559590.1
RP11-507B12.1
RP11-507B12.1
chr19_+_1407517 0.250 ENST00000336761.6
ENST00000233078.4
DAZAP1

DAZ associated protein 1

chr10_+_81107271 0.242 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chrX_-_104465358 0.242 ENST00000372578.3
ENST00000372575.1
ENST00000413579.1
TEX13A


testis expressed 13A


chr15_-_74753443 0.240 ENST00000567435.1
ENST00000564488.1
ENST00000565130.1
ENST00000563081.1
ENST00000565335.1
ENST00000395081.2
ENST00000361351.4
UBL7






ubiquitin-like 7 (bone marrow stromal cell-derived)






chr1_+_44444865 0.239 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr10_-_123734683 0.239 ENST00000369017.5
ENST00000369023.3
NSMCE4A

non-SMC element 4 homolog A (S. cerevisiae)

chr15_+_76135622 0.238 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2


ubiquitin-conjugating enzyme E2Q family member 2


chr15_+_68117844 0.237 ENST00000554054.1
SKOR1
SKI family transcriptional corepressor 1
chr5_-_74348371 0.235 ENST00000503568.1
RP11-229C3.2
RP11-229C3.2
chr3_+_10068095 0.235 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2



Fanconi anemia, complementation group D2



chr5_-_43313574 0.235 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr4_-_119274121 0.233 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr12_+_121416340 0.232 ENST00000257555.6
ENST00000400024.2
HNF1A

HNF1 homeobox A

chr22_+_38035459 0.232 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr6_+_32006042 0.232 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr3_+_38035610 0.231 ENST00000465644.1
VILL
villin-like
chr11_+_73498898 0.230 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48





mitochondrial ribosomal protein L48





chr17_-_42019836 0.230 ENST00000225992.3
PPY
pancreatic polypeptide
chr5_+_91378410 0.228 ENST00000507217.1
RP11-348J24.2
RP11-348J24.2
chrX_+_56100757 0.228 ENST00000433279.1
AL353698.1
Uncharacterized protein
chr15_-_74043816 0.228 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr8_-_59412717 0.227 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr1_+_84609944 0.227 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_41707778 0.226 ENST00000337495.5
ENST00000372597.1
ENST00000372596.1
SCMH1


sex comb on midleg homolog 1 (Drosophila)


chr13_-_111214015 0.224 ENST00000267328.3
RAB20
RAB20, member RAS oncogene family
chr3_-_122102065 0.224 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58


coiled-coil domain containing 58


chr19_-_3062465 0.223 ENST00000327141.4
AES
amino-terminal enhancer of split
chr15_-_91475747 0.223 ENST00000330334.3
ENST00000559898.1
ENST00000394272.3
HDDC3


HD domain containing 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0050894 determination of affect(GO:0050894)
0.8 6.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 0.8 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.2 0.9 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 0.6 GO:0009386 translational attenuation(GO:0009386)
0.2 0.5 GO:0035623 renal glucose absorption(GO:0035623)
0.2 1.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 2.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.6 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.5 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 2.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.3 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.4 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.2 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.8 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.3 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.3 GO:0014028 notochord formation(GO:0014028)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.4 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.2 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.1 0.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.1 0.2 GO:0033058 directional locomotion(GO:0033058)
0.1 0.2 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 1.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.4 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.1 0.2 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.3 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 3.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0015822 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.0 0.1 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0060708 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) spongiotrophoblast differentiation(GO:0060708)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.0 GO:0035565 regulation of pronephros size(GO:0035565)
0.0 2.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.3 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.2 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.3 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.0 GO:0010796 regulation of multivesicular body size(GO:0010796) intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.3 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.4 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.3 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.0 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0098855 HCN channel complex(GO:0098855)
0.2 0.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.1 2.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0036128 CatSper complex(GO:0036128)
0.1 0.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0002133 polycystin complex(GO:0002133)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 2.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.9 2.8 GO:0031877 somatostatin receptor binding(GO:0031877)
0.3 0.8 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.2 1.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.8 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 4.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.6 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.5 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.3 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.9 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.4 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.2 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 3.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 2.0 GO:0031005 filamin binding(GO:0031005)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0047696 G-protein coupled receptor kinase activity(GO:0004703) beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 3.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.3 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.1 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.6 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 4.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 0.9 REACTOME_OPSINS Genes involved in Opsins
0.1 0.6 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 3.0 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.9 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 4.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism