Motif ID: NR2E3

Z-value: 0.559


Transcription factors associated with NR2E3:

Gene SymbolEntrez IDGene Name
NR2E3 ENSG00000031544.10 NR2E3



Activity profile for motif NR2E3.

activity profile for motif NR2E3


Sorted Z-values histogram for motif NR2E3

Sorted Z-values for motif NR2E3



Network of associatons between targets according to the STRING database.



First level regulatory network of NR2E3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_66317967 0.371 ENST00000601398.1
AC090673.2
Uncharacterized protein
chr4_-_25865159 0.371 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr16_-_65106110 0.350 ENST00000562882.1
ENST00000567934.1
CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

chr11_+_121447469 0.349 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr14_-_60337684 0.334 ENST00000267484.5
RTN1
reticulon 1
chr7_-_121944491 0.327 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chrX_-_102565858 0.326 ENST00000449185.1
ENST00000536889.1
BEX2

brain expressed X-linked 2

chr12_-_45269251 0.325 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr2_+_149894968 0.311 ENST00000409642.3
LYPD6B
LY6/PLAUR domain containing 6B
chr12_-_45269430 0.307 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr22_-_36013368 0.291 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr7_+_114055052 0.290 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr12_-_45269769 0.287 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chrX_+_37639302 0.283 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr2_-_145275828 0.280 ENST00000392861.2
ENST00000409211.1
ZEB2

zinc finger E-box binding homeobox 2

chr11_-_32452357 0.267 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr19_-_36822551 0.266 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chrX_+_37639264 0.252 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr7_+_94023873 0.244 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr10_-_24770632 0.240 ENST00000596413.1
AL353583.1
AL353583.1
chr14_+_62462541 0.226 ENST00000430451.2
SYT16
synaptotagmin XVI
chr2_-_145277640 0.221 ENST00000539609.3
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_145277569 0.221 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr3_-_195310802 0.216 ENST00000421243.1
ENST00000453131.1
APOD

apolipoprotein D

chr11_+_34664014 0.210 ENST00000527935.1
EHF
ets homologous factor
chr8_+_40010989 0.203 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr14_+_71165292 0.197 ENST00000553682.1
RP6-65G23.1
RP6-65G23.1
chr11_+_111789580 0.192 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr3_+_181429704 0.192 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chr5_-_160365601 0.191 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1

RP11-109J4.1

chr4_-_76957214 0.189 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr9_-_90589402 0.189 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chr1_+_43613566 0.185 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr3_+_69915363 0.176 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr9_-_90589586 0.169 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr16_-_75529273 0.168 ENST00000390664.2
CHST6
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
chr8_+_30496078 0.162 ENST00000517349.1
SMIM18
small integral membrane protein 18
chr2_-_145278475 0.158 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr17_-_39150385 0.158 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr5_-_53115506 0.157 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1

CTD-2081C10.1

chr12_-_111142729 0.153 ENST00000546713.1
HVCN1
hydrogen voltage-gated channel 1
chr11_-_104905840 0.149 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr2_-_207082624 0.147 ENST00000458440.1
ENST00000437420.1
GPR1

G protein-coupled receptor 1

chr4_-_110723134 0.146 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr12_-_5849134 0.143 ENST00000545860.1
ANO2
anoctamin 2
chr3_+_186501979 0.142 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr1_-_204183071 0.141 ENST00000308302.3
GOLT1A
golgi transport 1A
chr12_+_32654965 0.138 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr5_-_87980753 0.138 ENST00000511014.2
LINC00461
long intergenic non-protein coding RNA 461
chr14_-_92247032 0.135 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB


catsper channel auxiliary subunit beta


chr4_-_23891693 0.135 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr4_-_44653636 0.135 ENST00000415895.4
ENST00000332990.5
YIPF7

Yip1 domain family, member 7

chr10_-_61122220 0.134 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C






family with sequence similarity 13, member C






chr3_+_172361483 0.132 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr4_-_23891658 0.132 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr12_-_18243075 0.132 ENST00000536890.1
RERGL
RERG/RAS-like
chr12_-_18890940 0.131 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1





phospholipase C, zeta 1





chr4_-_40477766 0.129 ENST00000507180.1
RBM47
RNA binding motif protein 47
chr1_+_164528866 0.129 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr4_-_110723194 0.128 ENST00000394635.3
CFI
complement factor I
chr4_-_110723335 0.124 ENST00000394634.2
CFI
complement factor I
chr2_-_207082748 0.123 ENST00000407325.2
ENST00000411719.1
GPR1

G protein-coupled receptor 1

chr4_-_20985632 0.123 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr12_+_41221794 0.121 ENST00000547849.1
CNTN1
contactin 1
chr5_+_140571902 0.120 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr4_+_147145709 0.117 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr16_+_222846 0.116 ENST00000251595.6
ENST00000397806.1
HBA2

hemoglobin, alpha 2

chr3_+_69915385 0.115 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr2_+_204732487 0.111 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr4_-_19458597 0.110 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr1_+_149858461 0.110 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr14_+_62037287 0.107 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr3_-_186262166 0.107 ENST00000307944.5
CRYGS
crystallin, gamma S
chr5_+_138210919 0.106 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
CTNNA1











catenin (cadherin-associated protein), alpha 1, 102kDa











chr16_+_2016821 0.106 ENST00000569210.2
ENST00000569714.1
RNF151

ring finger protein 151

chr11_-_88796803 0.104 ENST00000418177.2
ENST00000455756.2
GRM5

glutamate receptor, metabotropic 5

chrX_+_103810874 0.103 ENST00000372582.1
IL1RAPL2
interleukin 1 receptor accessory protein-like 2
chr9_+_12775011 0.102 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr3_+_186501336 0.101 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2


eukaryotic translation initiation factor 4A2


chrX_-_19504642 0.099 ENST00000469203.2
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr10_+_95372289 0.099 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr20_+_20033158 0.098 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
C20orf26






chromosome 20 open reading frame 26






chr16_+_67918708 0.098 ENST00000339176.3
ENST00000576758.1
NRN1L

neuritin 1-like

chr3_-_185826855 0.098 ENST00000306376.5
ETV5
ets variant 5
chr7_-_155604967 0.095 ENST00000297261.2
SHH
sonic hedgehog
chr1_-_8483723 0.094 ENST00000476556.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr10_+_115511434 0.094 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr10_+_52833883 0.093 ENST00000373980.4
PRKG1
protein kinase, cGMP-dependent, type I
chr3_-_185826718 0.092 ENST00000413301.1
ENST00000421809.1
ETV5

ets variant 5

chr9_-_104198042 0.092 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr5_+_133861339 0.092 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr20_-_62493217 0.092 ENST00000601296.1
C20ORF135
C20ORF135
chr12_-_81331460 0.091 ENST00000549417.1
LIN7A
lin-7 homolog A (C. elegans)
chr14_-_34420259 0.091 ENST00000250457.3
ENST00000547327.2
EGLN3

egl-9 family hypoxia-inducible factor 3

chr15_+_59908633 0.090 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_40724246 0.089 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr1_+_164529004 0.088 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1



pre-B-cell leukemia homeobox 1



chr7_-_78400598 0.087 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_188889737 0.087 ENST00000345063.3
TPRG1
tumor protein p63 regulated 1
chr12_+_32655110 0.087 ENST00000546442.1
ENST00000583694.1
FGD4

FYVE, RhoGEF and PH domain containing 4

chr7_-_79082867 0.086 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr5_-_90679145 0.085 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr3_-_120400960 0.085 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr7_+_29519486 0.085 ENST00000409041.4
CHN2
chimerin 2
chr7_-_79082786 0.081 ENST00000522391.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_184033551 0.081 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_-_36822595 0.080 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665


long intergenic non-protein coding RNA 665


chr11_-_104480019 0.080 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1


RP11-886D15.1


chr5_-_141338377 0.078 ENST00000510041.1
PCDH12
protocadherin 12
chr8_+_106330920 0.078 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr2_+_33359687 0.077 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr12_-_10541575 0.076 ENST00000540818.1
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr2_+_33359473 0.076 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_15479021 0.075 ENST00000428417.1
TMEM51
transmembrane protein 51
chr1_+_15479054 0.075 ENST00000376014.3
ENST00000451326.2
TMEM51

transmembrane protein 51

chr2_+_33359646 0.075 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr9_+_91605778 0.074 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
C9orf47


chromosome 9 open reading frame 47


chr1_-_144995074 0.074 ENST00000534536.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr17_-_62208169 0.073 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr10_-_103603523 0.072 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr11_+_65122216 0.071 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr4_-_76555657 0.070 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr13_-_38443860 0.070 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr20_-_30310336 0.070 ENST00000434194.1
ENST00000376062.2
BCL2L1

BCL2-like 1

chr5_+_140734570 0.070 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr1_+_22138758 0.068 ENST00000344642.2
ENST00000543870.1
LDLRAD2

low density lipoprotein receptor class A domain containing 2

chr11_+_92085707 0.068 ENST00000525166.1
FAT3
FAT atypical cadherin 3
chr4_+_174089904 0.068 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr6_-_28220002 0.067 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr11_+_122709200 0.067 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr1_-_8585945 0.066 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr2_+_145780662 0.066 ENST00000423031.1
TEX41
testis expressed 41 (non-protein coding)
chr12_+_56477093 0.066 ENST00000549672.1
ENST00000415288.2
ERBB3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

chr20_+_42574317 0.065 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr15_-_52587945 0.065 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr12_+_21525818 0.064 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP


islet amyloid polypeptide


chrX_-_15402498 0.064 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr1_-_8586084 0.064 ENST00000464972.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr19_+_37808831 0.063 ENST00000589801.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr1_+_24742264 0.063 ENST00000374399.4
ENST00000003912.3
ENST00000358028.4
ENST00000339255.2
NIPAL3



NIPA-like domain containing 3



chr5_-_138211051 0.062 ENST00000518785.1
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr2_-_224467002 0.062 ENST00000421386.1
ENST00000433889.1
SCG2

secretogranin II

chr11_-_74800799 0.061 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr7_-_115608304 0.061 ENST00000457268.1
TFEC
transcription factor EC
chr5_+_75904918 0.061 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQGAP2


IQ motif containing GTPase activating protein 2


chr1_+_166958497 0.060 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr1_+_166958504 0.060 ENST00000447624.1
MAEL
maelstrom spermatogenic transposon silencer
chr4_+_174089951 0.059 ENST00000512285.1
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr5_+_68788594 0.059 ENST00000396442.2
ENST00000380766.2
OCLN

occludin

chr18_+_32173276 0.059 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr2_+_121493717 0.059 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr2_-_158732340 0.058 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1



activin A receptor, type I



chrX_-_13835147 0.057 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr5_-_75919217 0.057 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr1_-_162346657 0.056 ENST00000367935.5
C1orf111
chromosome 1 open reading frame 111
chr5_-_124084493 0.055 ENST00000509799.1
ZNF608
zinc finger protein 608
chr7_-_7782204 0.055 ENST00000418534.2
AC007161.5
AC007161.5
chr6_+_45296048 0.055 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2



runt-related transcription factor 2



chr12_-_15815626 0.055 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr5_+_110559312 0.055 ENST00000508074.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr1_+_24118452 0.055 ENST00000421070.1
LYPLA2
lysophospholipase II
chr18_+_3448455 0.054 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr6_-_711395 0.054 ENST00000606285.1
RP11-532F6.3
RP11-532F6.3
chr8_+_38677850 0.054 ENST00000518809.1
ENST00000520611.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr3_-_169381183 0.054 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr10_-_14596140 0.054 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr1_-_85100703 0.053 ENST00000370624.1
C1orf180
chromosome 1 open reading frame 180
chr19_-_36019123 0.053 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr3_+_75955817 0.053 ENST00000487694.3
ENST00000602589.1
ROBO2

roundabout, axon guidance receptor, homolog 2 (Drosophila)

chr11_-_82745238 0.053 ENST00000531021.1
RAB30
RAB30, member RAS oncogene family
chr5_-_102455801 0.052 ENST00000508629.1
ENST00000399004.2
GIN1

gypsy retrotransposon integrase 1

chr2_-_224467093 0.052 ENST00000305409.2
SCG2
secretogranin II
chr6_-_42418999 0.052 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr19_+_3721719 0.051 ENST00000589378.1
ENST00000382008.3
TJP3

tight junction protein 3

chr19_-_14629224 0.051 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr8_-_15095832 0.051 ENST00000382080.1
SGCZ
sarcoglycan, zeta
chr7_+_142457315 0.050 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr13_-_103053946 0.050 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr8_-_62559366 0.050 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr4_+_76439095 0.049 ENST00000506261.1
THAP6
THAP domain containing 6
chr1_+_12042015 0.049 ENST00000412236.1
MFN2
mitofusin 2
chr1_-_98515395 0.049 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chrY_-_20935572 0.049 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2


heat shock transcription factor, Y linked 2


chr8_+_86999516 0.048 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr5_+_140710061 0.048 ENST00000517417.1
ENST00000378105.3
PCDHGA1

protocadherin gamma subfamily A, 1

chr22_+_41956767 0.045 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr13_+_102104980 0.045 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr15_-_33447055 0.045 ENST00000559047.1
ENST00000561249.1
FMN1

formin 1

chr1_+_63063152 0.045 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr12_+_18891045 0.044 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr22_+_18632666 0.044 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr4_+_100737954 0.044 ENST00000296414.7
ENST00000512369.1
DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides

chr6_-_152639479 0.043 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_59783941 0.042 ENST00000506884.1
ENST00000504876.2
PART1

prostate androgen-regulated transcript 1 (non-protein coding)

chr10_-_21186144 0.042 ENST00000377119.1
NEBL
nebulette
chr8_+_125954281 0.042 ENST00000510897.2
ENST00000533286.1
LINC00964

long intergenic non-protein coding RNA 964

chr11_-_61687739 0.042 ENST00000531922.1
ENST00000301773.5
RAB3IL1

RAB3A interacting protein (rabin3)-like 1

chr5_+_96079240 0.041 ENST00000515663.1
CAST
calpastatin
chr4_+_71588372 0.041 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr17_-_62207485 0.041 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.5 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.9 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0072299 visceral serous pericardium development(GO:0061032) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) peptidyl-serine autophosphorylation(GO:0036289) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055) insulin metabolic process(GO:1901142)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0097179 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis