Motif ID: NR2C1

Z-value: 0.292


Transcription factors associated with NR2C1:

Gene SymbolEntrez IDGene Name
NR2C1 ENSG00000120798.12 NR2C1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR2C1hg19_v2_chr12_-_95467267_95467350-0.511.6e-01Click!


Activity profile for motif NR2C1.

activity profile for motif NR2C1


Sorted Z-values histogram for motif NR2C1

Sorted Z-values for motif NR2C1



Network of associatons between targets according to the STRING database.



First level regulatory network of NR2C1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_38420623 0.339 ENST00000378482.2
 TSPAN7
tetraspanin 7
chrX_+_38420783 0.338 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
 TSPAN7


tetraspanin 7


chr17_-_1928621 0.268 ENST00000331238.6
 RTN4RL1
reticulon 4 receptor-like 1
chr2_-_38303218 0.207 ENST00000407341.1
ENST00000260630.3
 CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

chr19_+_6464243 0.104 ENST00000600229.1
ENST00000356762.3
 CRB3

crumbs homolog 3 (Drosophila)

chr19_+_4153598 0.101 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
 CREB3L3




cAMP responsive element binding protein 3-like 3




chr2_+_33701286 0.100 ENST00000403687.3
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr9_+_135037334 0.094 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
 NTNG2



netrin G2



chr1_-_156675564 0.087 ENST00000368220.1
 CRABP2
cellular retinoic acid binding protein 2
chr2_+_33701707 0.085 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
 RASGRP3


RAS guanyl releasing protein 3 (calcium and DAG-regulated)


chr2_-_202316169 0.065 ENST00000430254.1
 TRAK2
trafficking protein, kinesin binding 2
chr19_+_6464502 0.064 ENST00000308243.7
 CRB3
crumbs homolog 3 (Drosophila)
chr2_+_201936707 0.061 ENST00000433898.1
ENST00000454214.1
 NDUFB3

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

chr19_+_16771936 0.061 ENST00000187762.2
ENST00000599479.1
 TMEM38A

transmembrane protein 38A

chr7_-_229557 0.058 ENST00000514988.1
 AC145676.2
Uncharacterized protein
chr3_+_184055240 0.057 ENST00000383847.2
 FAM131A
family with sequence similarity 131, member A
chr1_-_12679171 0.057 ENST00000606790.1
 RP11-474O21.5
RP11-474O21.5
chr2_+_201936458 0.056 ENST00000237889.4
 NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr19_+_51293672 0.055 ENST00000270593.1
ENST00000270594.3
 ACPT

acid phosphatase, testicular

chr6_+_31515337 0.055 ENST00000376148.4
ENST00000376145.4
 NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr10_+_24755416 0.055 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
 KIAA1217


KIAA1217


chr2_-_201936302 0.055 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
 FAM126B



family with sequence similarity 126, member B



chr1_+_45140360 0.055 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
 C1orf228




chromosome 1 open reading frame 228




chr2_-_202316260 0.053 ENST00000332624.3
 TRAK2
trafficking protein, kinesin binding 2
chr12_-_22487588 0.051 ENST00000381424.3
 ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr17_-_39743139 0.050 ENST00000167586.6
 KRT14
keratin 14
chr3_+_179065474 0.049 ENST00000471841.1
ENST00000280653.7
 MFN1

mitofusin 1

chr17_+_37821593 0.049 ENST00000578283.1
 TCAP
titin-cap
chr7_+_120969045 0.045 ENST00000222462.2
 WNT16
wingless-type MMTV integration site family, member 16
chr3_+_183903811 0.044 ENST00000429586.2
ENST00000292808.5
 ABCF3

ATP-binding cassette, sub-family F (GCN20), member 3

chr15_+_82555169 0.043 ENST00000565432.1
ENST00000427381.2
 FAM154B

family with sequence similarity 154, member B

chr6_+_30594619 0.041 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
 ATAT1






alpha tubulin acetyltransferase 1






chr2_-_42721110 0.040 ENST00000394973.4
ENST00000306078.1
 KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr3_-_50605077 0.040 ENST00000426034.1
ENST00000441239.1
 C3orf18

chromosome 3 open reading frame 18

chr2_+_202316392 0.039 ENST00000194530.3
ENST00000392249.2
 STRADB

STE20-related kinase adaptor beta

chr3_+_46538981 0.039 ENST00000296142.3
 RTP3
receptor (chemosensory) transporter protein 3
chr20_+_19870167 0.035 ENST00000440354.2
 RIN2
Ras and Rab interactor 2
chrX_-_132095419 0.035 ENST00000370836.2
ENST00000521489.1
 HS6ST2

heparan sulfate 6-O-sulfotransferase 2

chr19_-_48867291 0.034 ENST00000435956.3
 TMEM143
transmembrane protein 143
chr12_-_24715376 0.033 ENST00000446891.2
ENST00000429944.2
 RP11-444D3.1

RP11-444D3.1

chr12_-_24715478 0.032 ENST00000456299.2
ENST00000540811.1
 RP11-444D3.1

RP11-444D3.1

chr15_-_43863695 0.032 ENST00000439195.1
 PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr19_-_51289374 0.032 ENST00000563228.1
 CTD-2568A17.1
CTD-2568A17.1
chr8_-_145028013 0.032 ENST00000354958.2
 PLEC
plectin
chr4_-_111544207 0.031 ENST00000557119.2
 PITX2
paired-like homeodomain 2
chr22_+_41777927 0.031 ENST00000266304.4
 TEF
thyrotrophic embryonic factor
chr5_-_42812143 0.030 ENST00000514985.1
 SEPP1
selenoprotein P, plasma, 1
chr2_-_164592497 0.029 ENST00000333129.3
ENST00000409634.1
 FIGN

fidgetin

chr19_+_676385 0.029 ENST00000166139.4
 FSTL3
follistatin-like 3 (secreted glycoprotein)
chr1_+_145727681 0.028 ENST00000417171.1
ENST00000451928.2
 PDZK1

PDZ domain containing 1

chr11_+_64073699 0.028 ENST00000405666.1
ENST00000468670.1
 ESRRA

estrogen-related receptor alpha

chr5_-_87564620 0.028 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
 TMEM161B




transmembrane protein 161B




chr3_+_107318157 0.027 ENST00000406780.1
 BBX
bobby sox homolog (Drosophila)
chr1_-_155880672 0.027 ENST00000609492.1
ENST00000368322.3
 RIT1

Ras-like without CAAX 1

chr6_+_43737939 0.027 ENST00000372067.3
 VEGFA
vascular endothelial growth factor A
chr19_-_48867171 0.027 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
 TMEM143


transmembrane protein 143


chr2_+_109745655 0.024 ENST00000418513.1
 SH3RF3
SH3 domain containing ring finger 3
chr2_+_219135115 0.024 ENST00000248451.3
ENST00000273077.4
 PNKD

paroxysmal nonkinesigenic dyskinesia

chr4_+_159593418 0.024 ENST00000507475.1
ENST00000307738.5
 ETFDH

electron-transferring-flavoprotein dehydrogenase

chr1_-_155881156 0.023 ENST00000539040.1
ENST00000368323.3
 RIT1

Ras-like without CAAX 1

chr2_-_163100045 0.023 ENST00000188790.4
 FAP
fibroblast activation protein, alpha
chr9_-_77643189 0.022 ENST00000376837.3
 C9orf41
chromosome 9 open reading frame 41
chr2_-_163099885 0.021 ENST00000443424.1
 FAP
fibroblast activation protein, alpha
chr6_+_10585979 0.021 ENST00000265012.4
 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr3_-_50605150 0.021 ENST00000357203.3
 C3orf18
chromosome 3 open reading frame 18
chr11_+_67798090 0.021 ENST00000313468.5
 NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr19_-_18548921 0.020 ENST00000545187.1
ENST00000578352.1
 ISYNA1

inositol-3-phosphate synthase 1

chr1_+_25071848 0.020 ENST00000374379.4
 CLIC4
chloride intracellular channel 4
chr2_-_219134822 0.020 ENST00000444053.1
ENST00000248450.4
 AAMP

angio-associated, migratory cell protein

chr11_+_67798114 0.019 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
 NDUFS8



NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)



chr4_-_99064387 0.018 ENST00000295268.3
 STPG2
sperm-tail PG-rich repeat containing 2
chr11_-_64900791 0.018 ENST00000531018.1
 SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr11_+_67798363 0.018 ENST00000525628.1
 NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr20_-_44485835 0.018 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
 ACOT8


acyl-CoA thioesterase 8


chr12_-_90049878 0.018 ENST00000359142.3
 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_+_46926326 0.017 ENST00000394861.2
 SOCS5
suppressor of cytokine signaling 5
chr12_-_90049828 0.017 ENST00000261173.2
ENST00000348959.3
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr12_+_57854274 0.017 ENST00000528432.1
 GLI1
GLI family zinc finger 1
chr2_-_154335300 0.017 ENST00000325926.3
 RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr5_-_42811986 0.017 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
 SEPP1


selenoprotein P, plasma, 1


chr10_+_127661942 0.016 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
 FANK1


fibronectin type III and ankyrin repeat domains 1


chr6_+_57037089 0.016 ENST00000370693.5
 BAG2
BCL2-associated athanogene 2
chr8_+_110656344 0.016 ENST00000499579.1
 RP11-422N16.3
Uncharacterized protein
chr4_-_76598296 0.015 ENST00000395719.3
 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr4_+_26321284 0.015 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
 RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr20_+_327413 0.015 ENST00000609179.1
 NRSN2
neurensin 2
chr7_+_121513143 0.015 ENST00000393386.2
 PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr19_-_51289436 0.014 ENST00000562076.1
 CTD-2568A17.1
CTD-2568A17.1
chr19_-_18548962 0.014 ENST00000317018.6
ENST00000581800.1
ENST00000583534.1
ENST00000457269.4
ENST00000338128.8
 ISYNA1




inositol-3-phosphate synthase 1




chr14_+_21492331 0.014 ENST00000533984.1
ENST00000532213.2
 AL161668.5

AL161668.5

chr1_-_55089191 0.013 ENST00000302250.2
ENST00000371304.2
 FAM151A

family with sequence similarity 151, member A

chr4_-_76598326 0.013 ENST00000503660.1
 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr11_-_116663127 0.013 ENST00000433069.1
ENST00000542499.1
 APOA5

apolipoprotein A-V

chr17_+_73997419 0.013 ENST00000425876.2
 CDK3
cyclin-dependent kinase 3
chr2_-_219134343 0.013 ENST00000447885.1
ENST00000420660.1
 AAMP

angio-associated, migratory cell protein

chr7_+_100770328 0.012 ENST00000223095.4
ENST00000445463.2
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr2_-_219433014 0.012 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
 USP37




ubiquitin specific peptidase 37




chr12_+_67663056 0.012 ENST00000545606.1
 CAND1
cullin-associated and neddylation-dissociated 1
chr4_-_111544254 0.012 ENST00000306732.3
 PITX2
paired-like homeodomain 2
chr16_+_83932684 0.012 ENST00000262430.4
 MLYCD
malonyl-CoA decarboxylase
chr9_-_34397800 0.012 ENST00000297623.2
 C9orf24
chromosome 9 open reading frame 24
chr2_+_33701684 0.012 ENST00000442390.1
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_+_104005272 0.011 ENST00000369983.3
 GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr1_+_26872324 0.011 ENST00000531382.1
 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_+_219433588 0.011 ENST00000295701.5
 RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr10_-_118502070 0.011 ENST00000369209.3
 HSPA12A
heat shock 70kDa protein 12A
chr12_-_53729525 0.011 ENST00000303846.3
 SP7
Sp7 transcription factor
chr1_-_150944411 0.011 ENST00000368949.4
 CERS2
ceramide synthase 2
chr2_-_25194476 0.011 ENST00000534855.1
 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr11_-_45939374 0.010 ENST00000533151.1
ENST00000241041.3
 PEX16

peroxisomal biogenesis factor 16

chr15_+_45422131 0.010 ENST00000321429.4
 DUOX1
dual oxidase 1
chr11_-_62439727 0.010 ENST00000528862.1
 C11orf48
chromosome 11 open reading frame 48
chr2_+_46926048 0.010 ENST00000306503.5
 SOCS5
suppressor of cytokine signaling 5
chr2_+_109237717 0.010 ENST00000409441.1
 LIMS1
LIM and senescent cell antigen-like domains 1
chr12_+_48499883 0.010 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
 PFKM


phosphofructokinase, muscle


chr1_+_44412577 0.009 ENST00000372343.3
 IPO13
importin 13
chr1_-_101491319 0.009 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
 DPH5


diphthamide biosynthesis 5


chr8_+_96037205 0.009 ENST00000396124.4
 NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_-_48499826 0.008 ENST00000551798.1
 SENP1
SUMO1/sentrin specific peptidase 1
chr3_+_42897512 0.008 ENST00000493193.1
 ACKR2
atypical chemokine receptor 2
chr18_-_54318353 0.008 ENST00000590954.1
ENST00000540155.1
 TXNL1

thioredoxin-like 1

chr12_-_8088773 0.008 ENST00000544291.1
 SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr19_+_48828788 0.007 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
 EMP3


epithelial membrane protein 3


chr19_+_10197463 0.007 ENST00000590378.1
ENST00000397881.3
 C19orf66

chromosome 19 open reading frame 66

chr19_+_48828582 0.006 ENST00000270221.6
ENST00000596315.1
 EMP3

epithelial membrane protein 3

chr9_-_140513231 0.006 ENST00000371417.3
 C9orf37
chromosome 9 open reading frame 37
chr1_+_160097462 0.006 ENST00000447527.1
 ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr15_+_45422178 0.006 ENST00000389037.3
ENST00000558322.1
 DUOX1

dual oxidase 1

chr1_-_45140227 0.006 ENST00000372237.3
 TMEM53
transmembrane protein 53
chr11_-_45939565 0.006 ENST00000525192.1
ENST00000378750.5
 PEX16

peroxisomal biogenesis factor 16

chr10_-_73479546 0.006 ENST00000441508.2
 C10orf105
chromosome 10 open reading frame 105
chr17_-_15902951 0.006 ENST00000472495.1
 ZSWIM7
zinc finger, SWIM-type containing 7
chrX_-_19817869 0.005 ENST00000379698.4
 SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_226374373 0.005 ENST00000366812.5
 ACBD3
acyl-CoA binding domain containing 3
chr1_-_45253377 0.005 ENST00000372207.3
 BEST4
bestrophin 4
chr12_+_6494285 0.005 ENST00000541102.1
 LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr19_-_41256207 0.005 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
 C19orf54



chromosome 19 open reading frame 54



chr8_+_96037255 0.004 ENST00000286687.4
 NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_-_109219937 0.004 ENST00000546697.1
 SSH1
slingshot protein phosphatase 1
chr17_-_15903002 0.004 ENST00000399277.1
 ZSWIM7
zinc finger, SWIM-type containing 7
chr2_-_25194963 0.003 ENST00000264711.2
 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr22_+_30163340 0.003 ENST00000330029.6
ENST00000401406.3
 UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr3_+_113465866 0.003 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
 ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr15_+_90728145 0.003 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
 SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr12_-_22487618 0.003 ENST00000404299.3
ENST00000396037.4
 ST8SIA1

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

chr2_+_151485403 0.003 ENST00000413247.1
ENST00000423428.1
ENST00000427615.1
ENST00000443811.1
 AC104777.4



AC104777.4



chr9_-_139137648 0.003 ENST00000358701.5
 QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr1_+_215255136 0.002 ENST00000478774.1
 KCNK2
potassium channel, subfamily K, member 2
chr10_+_64564469 0.002 ENST00000373783.1
 ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr17_-_15902903 0.002 ENST00000486655.1
 ZSWIM7
zinc finger, SWIM-type containing 7
chr20_-_57607347 0.002 ENST00000395663.1
ENST00000395659.1
ENST00000243997.3
 ATP5E


ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit


chr3_-_126236588 0.001 ENST00000383579.3
 UROC1
urocanate hydratase 1
chr12_-_48500085 0.001 ENST00000549518.1
 SENP1
SUMO1/sentrin specific peptidase 1
chr17_-_80023659 0.000 ENST00000578907.1
ENST00000577907.1
ENST00000578176.1
ENST00000582529.1
 DUS1L



dihydrouridine synthase 1-like (S. cerevisiae)




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.0 GO:1902362 melanocyte apoptotic process(GO:1902362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols