Motif ID: NR1I3

Z-value: 0.309


Transcription factors associated with NR1I3:

Gene SymbolEntrez IDGene Name
NR1I3 ENSG00000143257.7 NR1I3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161207986_161208000-0.771.5e-02Click!


Activity profile for motif NR1I3.

activity profile for motif NR1I3


Sorted Z-values histogram for motif NR1I3

Sorted Z-values for motif NR1I3



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1I3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_82165350 0.391 ENST00000359929.3
 LPHN2
latrophilin 2
chr20_-_45142154 0.374 ENST00000347606.4
ENST00000457685.2
 ZNF334

zinc finger protein 334

chr6_+_32407619 0.289 ENST00000395388.2
ENST00000374982.5
 HLA-DRA

major histocompatibility complex, class II, DR alpha

chr8_-_109799793 0.287 ENST00000297459.3
 TMEM74
transmembrane protein 74
chr1_-_23886285 0.287 ENST00000374561.5
 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr12_+_53817633 0.274 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
 AMHR2


anti-Mullerian hormone receptor, type II


chr2_-_69180083 0.192 ENST00000328895.4
 GKN2
gastrokine 2
chr4_-_82136114 0.114 ENST00000395578.1
ENST00000418486.2
 PRKG2

protein kinase, cGMP-dependent, type II

chr18_+_61557781 0.112 ENST00000443281.1
 SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr2_-_228028829 0.106 ENST00000396625.3
ENST00000329662.7
 COL4A4

collagen, type IV, alpha 4

chr19_-_44306590 0.101 ENST00000377950.3
 LYPD5
LY6/PLAUR domain containing 5
chr2_-_69180012 0.098 ENST00000481498.1
 GKN2
gastrokine 2
chr5_+_139055055 0.085 ENST00000511457.1
 CXXC5
CXXC finger protein 5
chr3_-_108476231 0.084 ENST00000295755.6
 RETNLB
resistin like beta
chr19_+_12203100 0.072 ENST00000596883.1
 ZNF788
zinc finger family member 788
chr1_-_21625486 0.067 ENST00000481130.2
 ECE1
endothelin converting enzyme 1
chr7_-_56160625 0.065 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
 PHKG1



phosphorylase kinase, gamma 1 (muscle)



chr14_-_50506589 0.065 ENST00000553914.2
 RP11-58E21.3
RP11-58E21.3
chr20_-_44007014 0.058 ENST00000372726.3
ENST00000537995.1
 TP53TG5

TP53 target 5

chr14_-_22005018 0.057 ENST00000546363.1
 SALL2
spalt-like transcription factor 2
chr9_-_91793675 0.057 ENST00000375835.4
ENST00000375830.1
 SHC3

SHC (Src homology 2 domain containing) transforming protein 3

chr15_+_43885252 0.052 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
 CKMT1B



creatine kinase, mitochondrial 1B



chr14_-_22005197 0.051 ENST00000541965.1
 SALL2
spalt-like transcription factor 2
chr11_-_82611448 0.048 ENST00000393399.2
ENST00000313010.3
 PRCP

prolylcarboxypeptidase (angiotensinase C)

chr5_+_139055021 0.048 ENST00000502716.1
ENST00000503511.1
 CXXC5

CXXC finger protein 5

chr9_+_124048864 0.047 ENST00000545652.1
 GSN
gelsolin
chr19_-_58919815 0.042 ENST00000597980.1
 CTD-2619J13.14
CTD-2619J13.14
chr19_+_12203069 0.042 ENST00000339302.4
ENST00000430298.2
 ZNF788
ZNF788
Zinc finger protein 788
zinc finger family member 788
chr11_-_61124266 0.042 ENST00000539890.1
 CYB561A3
cytochrome b561 family, member A3
chrX_-_15619076 0.038 ENST00000252519.3
 ACE2
angiotensin I converting enzyme 2
chrX_-_153583257 0.037 ENST00000438732.1
 FLNA
filamin A, alpha
chr19_+_676385 0.037 ENST00000166139.4
 FSTL3
follistatin-like 3 (secreted glycoprotein)
chr7_-_56160666 0.037 ENST00000297373.2
 PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr9_+_35605274 0.036 ENST00000336395.5
 TESK1
testis-specific kinase 1
chr7_+_100770328 0.035 ENST00000223095.4
ENST00000445463.2
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_-_20755140 0.034 ENST00000418743.1
ENST00000426428.1
 RP4-749H3.1

long intergenic non-protein coding RNA 1141

chr2_+_177015950 0.033 ENST00000306324.3
 HOXD4
homeobox D4
chr18_-_19283649 0.033 ENST00000584464.1
ENST00000578270.1
 ABHD3

abhydrolase domain containing 3

chr2_-_209118974 0.032 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
 IDH1


isocitrate dehydrogenase 1 (NADP+), soluble


chr1_+_15250596 0.031 ENST00000361144.5
 KAZN
kazrin, periplakin interacting protein
chr11_-_61124776 0.031 ENST00000542361.1
 CYB561A3
cytochrome b561 family, member A3
chr11_-_61124711 0.031 ENST00000536915.1
 CYB561A3
cytochrome b561 family, member A3
chr9_+_75766763 0.031 ENST00000456643.1
ENST00000415424.1
 ANXA1

annexin A1

chr14_-_22005062 0.029 ENST00000317492.5
 SALL2
spalt-like transcription factor 2
chr17_-_26694979 0.029 ENST00000438614.1
 VTN
vitronectin
chr4_+_70894130 0.027 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3


histatin 3


chr6_+_33422343 0.027 ENST00000395064.2
 ZBTB9
zinc finger and BTB domain containing 9
chr17_-_26695013 0.027 ENST00000555059.2
 CTB-96E2.2
Homeobox protein SEBOX
chr11_-_104480019 0.025 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
 RP11-886D15.1


RP11-886D15.1


chr1_+_44401479 0.024 ENST00000438616.3
 ARTN
artemin
chr10_+_80027085 0.024 ENST00000415959.1
 LINC00595
long intergenic non-protein coding RNA 595
chr18_-_19284724 0.024 ENST00000580981.1
ENST00000289119.2
 ABHD3

abhydrolase domain containing 3

chr11_+_62556596 0.023 ENST00000526546.1
 TMEM179B
transmembrane protein 179B
chr11_-_83393303 0.022 ENST00000398304.1
ENST00000420775.2
 DLG2

discs, large homolog 2 (Drosophila)

chr2_-_128642434 0.020 ENST00000393001.1
 AMMECR1L
AMMECR1-like
chrX_-_50386648 0.020 ENST00000460112.3
 SHROOM4
shroom family member 4
chr1_-_20126365 0.020 ENST00000294543.6
ENST00000375122.2
 TMCO4

transmembrane and coiled-coil domains 4

chr1_+_113217043 0.019 ENST00000413052.2
 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr15_+_43985084 0.019 ENST00000434505.1
ENST00000411750.1
 CKMT1A

creatine kinase, mitochondrial 1A

chr1_-_151119087 0.018 ENST00000341697.3
ENST00000368914.3
 SEMA6C

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr13_+_24883703 0.017 ENST00000332018.4
 C1QTNF9
C1q and tumor necrosis factor related protein 9
chr12_-_108991778 0.016 ENST00000549447.1
 TMEM119
transmembrane protein 119
chr6_+_108487245 0.014 ENST00000368986.4
 NR2E1
nuclear receptor subfamily 2, group E, member 1
chr1_-_33336414 0.014 ENST00000373471.3
ENST00000609187.1
 FNDC5

fibronectin type III domain containing 5

chr2_-_241075706 0.013 ENST00000607357.1
ENST00000307266.3
 MYEOV2

myeloma overexpressed 2

chr19_-_48894104 0.013 ENST00000597017.1
 KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_1690014 0.012 ENST00000400922.2
ENST00000342348.5
 NADK

NAD kinase

chr19_+_58919992 0.012 ENST00000306910.4
ENST00000598901.1
ENST00000593920.1
ENST00000596281.1
 ZNF584



zinc finger protein 584



chr5_-_135528822 0.011 ENST00000607574.1
 AC009014.3
AC009014.3
chr1_+_59250815 0.010 ENST00000544621.1
ENST00000419531.2
 RP4-794H19.2

long intergenic non-protein coding RNA 1135

chr11_+_933555 0.010 ENST00000534485.1
 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr15_-_42343388 0.009 ENST00000399518.3
 PLA2G4E
phospholipase A2, group IVE
chr19_+_58920102 0.009 ENST00000599238.1
ENST00000322834.7
 ZNF584

zinc finger protein 584

chr9_-_75567962 0.009 ENST00000297785.3
ENST00000376939.1
 ALDH1A1

aldehyde dehydrogenase 1 family, member A1

chr6_-_31509714 0.008 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
 DDX39B









DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B









chr11_+_63137251 0.008 ENST00000310969.4
ENST00000279178.3
 SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chr17_-_33390667 0.007 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
 RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr1_+_32930647 0.006 ENST00000609129.1
 ZBTB8B
zinc finger and BTB domain containing 8B
chr10_+_47658234 0.006 ENST00000447511.2
ENST00000537271.1
 ANTXRL

anthrax toxin receptor-like

chr19_-_46285646 0.006 ENST00000458663.2
 DMPK
dystrophia myotonica-protein kinase
chr13_-_20806440 0.006 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
 GJB6


gap junction protein, beta 6, 30kDa


chr1_+_43803475 0.006 ENST00000372470.3
ENST00000413998.2
 MPL

myeloproliferative leukemia virus oncogene

chr6_-_31509506 0.006 ENST00000449757.1
 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr8_-_53626974 0.006 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
 RB1CC1



RB1-inducible coiled-coil 1



chr1_+_160097462 0.006 ENST00000447527.1
 ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr12_+_53693812 0.005 ENST00000549488.1
 C12orf10
chromosome 12 open reading frame 10
chr9_-_114937676 0.004 ENST00000374270.3
 SUSD1
sushi domain containing 1
chr12_-_108991812 0.004 ENST00000392806.3
ENST00000547567.1
 TMEM119

transmembrane protein 119

chr12_-_53729525 0.003 ENST00000303846.3
 SP7
Sp7 transcription factor
chr1_-_27682962 0.003 ENST00000486046.1
 MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr16_+_67906919 0.002 ENST00000358933.5
 EDC4
enhancer of mRNA decapping 4
chr5_-_176936817 0.002 ENST00000502885.1
ENST00000506493.1
 DOK3

docking protein 3

chr11_-_57089671 0.002 ENST00000532437.1
 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr7_+_101460882 0.002 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
 CUX1




cut-like homeobox 1




chr6_-_43496605 0.001 ENST00000455285.2
 XPO5
exportin 5
chr19_-_49140692 0.001 ENST00000222122.5
 DBP
D site of albumin promoter (albumin D-box) binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.0 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events