Motif ID: NKX6-3

Z-value: 0.143


Transcription factors associated with NKX6-3:

Gene SymbolEntrez IDGene Name
NKX6-3 ENSG00000165066.11 NKX6-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX6-3hg19_v2_chr8_-_41508855_415088550.432.5e-01Click!


Activity profile for motif NKX6-3.

activity profile for motif NKX6-3


Sorted Z-values histogram for motif NKX6-3

Sorted Z-values for motif NKX6-3



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_88247083 0.099 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chr12_-_52761262 0.095 ENST00000257901.3
KRT85
keratin 85
chr9_+_125133315 0.093 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr1_-_204183071 0.067 ENST00000308302.3
GOLT1A
golgi transport 1A
chr9_+_125132803 0.050 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr7_+_129984630 0.050 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chr9_+_125133467 0.045 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr13_-_81801115 0.030 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr8_+_92261516 0.029 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr1_-_232651312 0.025 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_+_80584903 0.019 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr2_-_44550441 0.014 ENST00000420756.1
ENST00000444696.1
PREPL

prolyl endopeptidase-like

chr15_+_48051920 0.013 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_-_142780280 0.013 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_-_191000172 0.013 ENST00000427544.2
UTS2B
urotensin 2B
chr1_-_208417620 0.012 ENST00000367033.3
PLXNA2
plexin A2
chrX_+_150565038 0.011 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr3_-_141747950 0.010 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_+_18549645 0.010 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr18_+_32558208 0.007 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_+_26324474 0.006 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr9_-_215744 0.006 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr14_-_51027838 0.006 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr19_-_6057282 0.006 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr11_+_22689648 0.005 ENST00000278187.3
GAS2
growth arrest-specific 2
chr5_-_139726181 0.005 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr20_+_30697298 0.005 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr3_-_141719195 0.005 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_+_124329336 0.005 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr14_+_88851874 0.004 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7



spermatogenesis associated 7



chr18_+_20494078 0.004 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8



retinoblastoma binding protein 8



chrX_-_110655306 0.004 ENST00000371993.2
DCX
doublecortin
chr18_+_32558380 0.004 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr8_-_90769422 0.003 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1

RP11-37B2.1

chr15_+_90735145 0.003 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr4_+_76481258 0.002 ENST00000311623.4
ENST00000435974.2
C4orf26

chromosome 4 open reading frame 26

chrX_+_47696275 0.002 ENST00000376954.1
ENST00000338637.7
ZNF81

zinc finger protein 81

chr14_+_88852059 0.001 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr7_+_138145076 0.000 ENST00000343526.4
TRIM24
tripartite motif containing 24

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)