Motif ID: NKX6-2

Z-value: 0.428


Transcription factors associated with NKX6-2:

Gene SymbolEntrez IDGene Name
NKX6-2 ENSG00000148826.6 NKX6-2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX6-2hg19_v2_chr10_-_134599556_1345996530.088.4e-01Click!


Activity profile for motif NKX6-2.

activity profile for motif NKX6-2


Sorted Z-values histogram for motif NKX6-2

Sorted Z-values for motif NKX6-2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_166711804 0.612 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr20_-_7921090 0.569 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_-_138287168 0.440 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr8_-_82395461 0.383 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr1_-_49242553 0.324 ENST00000371833.3
BEND5
BEN domain containing 5
chr4_+_71384257 0.307 ENST00000339336.4
AMTN
amelotin
chr6_-_113953705 0.295 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr4_+_71384300 0.250 ENST00000504451.1
AMTN
amelotin
chr22_-_33968239 0.249 ENST00000452586.2
ENST00000421768.1
LARGE

like-glycosyltransferase

chr1_+_209878182 0.247 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr7_-_84122033 0.183 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_104831472 0.180 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chrX_+_135230712 0.175 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr11_-_126810521 0.165 ENST00000530572.1
RP11-688I9.4
RP11-688I9.4
chr2_-_73520667 0.164 ENST00000545030.1
ENST00000436467.2
EGR4

early growth response 4

chr12_+_54422142 0.156 ENST00000243108.4
HOXC6
homeobox C6
chr19_+_31640362 0.156 ENST00000598480.1
AC020952.1
Uncharacterized protein
chr16_-_67517716 0.156 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr19_+_56280507 0.153 ENST00000341750.4
RFPL4AL1
ret finger protein-like 4A-like 1
chr6_+_114178512 0.149 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_201617450 0.142 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1


neuron navigator 1


chr3_+_156799587 0.142 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr17_-_56494713 0.140 ENST00000407977.2
RNF43
ring finger protein 43
chr1_+_201617264 0.140 ENST00000367296.4
NAV1
neuron navigator 1
chr14_+_86401039 0.139 ENST00000557195.1
CTD-2341M24.1
CTD-2341M24.1
chr15_+_49715449 0.138 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr1_-_150738261 0.136 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr8_+_92114060 0.135 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr6_+_12007897 0.135 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chrX_+_68835911 0.133 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA





ectodysplasin A





chr12_-_94673956 0.129 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr9_-_16215897 0.128 ENST00000433347.1
C9orf92
chromosome 9 open reading frame 92
chr13_-_33760216 0.128 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_-_58295712 0.126 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_65593784 0.125 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr8_+_104831554 0.121 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_25479811 0.121 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr4_-_136809245 0.121 ENST00000504365.1
LINC00613
long intergenic non-protein coding RNA 613
chr2_-_208030647 0.118 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_+_6625733 0.117 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1

PRKCQ antisense RNA 1

chr12_-_28124903 0.116 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr14_+_52164820 0.115 ENST00000554167.1
FRMD6
FERM domain containing 6
chr6_+_116850174 0.112 ENST00000416171.2
ENST00000368597.2
ENST00000452373.1
ENST00000405399.1
FAM26D



family with sequence similarity 26, member D



chr3_-_79816965 0.111 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_+_11864458 0.109 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1


lipin 1


chr11_+_7618413 0.105 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_208030295 0.105 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_-_80457385 0.104 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr11_-_26744908 0.103 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_+_174933899 0.100 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr6_+_12007963 0.098 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr16_+_31271274 0.095 ENST00000287497.8
ENST00000544665.3
ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

chr1_+_210501589 0.094 ENST00000413764.2
ENST00000541565.1
HHAT

hedgehog acyltransferase

chr18_+_72922710 0.092 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr14_+_63671105 0.091 ENST00000316754.3
RHOJ
ras homolog family member J
chr1_+_109265033 0.091 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr4_+_55095264 0.088 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr1_+_110993795 0.088 ENST00000271331.3
PROK1
prokineticin 1
chr16_+_25228242 0.087 ENST00000219660.5
AQP8
aquaporin 8
chr9_+_82186872 0.084 ENST00000376544.3
ENST00000376520.4
TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

chr3_+_68053359 0.083 ENST00000478136.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr3_-_71294304 0.082 ENST00000498215.1
FOXP1
forkhead box P1
chr14_+_52164675 0.081 ENST00000555936.1
FRMD6
FERM domain containing 6
chr11_-_9088284 0.081 ENST00000531429.1
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr4_+_183370146 0.079 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr9_+_34652164 0.079 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr6_-_131277510 0.078 ENST00000525193.1
ENST00000527659.1
EPB41L2

erythrocyte membrane protein band 4.1-like 2

chr4_-_108204904 0.076 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr17_-_56494882 0.076 ENST00000584437.1
RNF43
ring finger protein 43
chr16_+_84801852 0.075 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr16_+_53483983 0.074 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr2_-_208030886 0.073 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr14_-_98444461 0.072 ENST00000499006.2
C14orf64
chromosome 14 open reading frame 64
chr11_+_6942205 0.072 ENST00000317834.3
OR2D3
olfactory receptor, family 2, subfamily D, member 3
chr1_-_226926864 0.071 ENST00000429204.1
ENST00000366784.1
ITPKB

inositol-trisphosphate 3-kinase B

chr9_+_109685630 0.069 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr7_+_16700806 0.069 ENST00000446596.1
ENST00000438834.1
BZW2

basic leucine zipper and W2 domains 2

chr2_-_74570520 0.068 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5





solute carrier family 4 (sodium bicarbonate cotransporter), member 5





chr18_+_42260059 0.066 ENST00000426838.4
SETBP1
SET binding protein 1
chr21_-_36421626 0.064 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr10_+_32873190 0.064 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr18_-_52989217 0.064 ENST00000570287.2
TCF4
transcription factor 4
chr4_-_108204846 0.064 ENST00000513208.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr9_+_82187487 0.063 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chr18_-_52989525 0.063 ENST00000457482.3
TCF4
transcription factor 4
chr1_-_110155671 0.062 ENST00000351050.3
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr1_+_218683438 0.060 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr18_-_53255379 0.059 ENST00000565908.2
TCF4
transcription factor 4
chr3_+_140981456 0.059 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr10_+_6625605 0.058 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1

PRKCQ antisense RNA 1

chr21_-_36421535 0.058 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1


runt-related transcription factor 1


chr15_+_79166065 0.058 ENST00000559690.1
ENST00000559158.1
MORF4L1

mortality factor 4 like 1

chr17_-_10276319 0.057 ENST00000252172.4
ENST00000418404.3
MYH13

myosin, heavy chain 13, skeletal muscle

chr10_-_73848086 0.056 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_145477060 0.056 ENST00000369308.3
LIX1L
Lix1 homolog (mouse)-like
chr6_-_160209471 0.055 ENST00000539948.1
TCP1
t-complex 1
chr22_-_29137771 0.055 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2









checkpoint kinase 2









chr1_+_244515930 0.053 ENST00000366537.1
ENST00000308105.4
C1orf100

chromosome 1 open reading frame 100

chr5_-_20575959 0.052 ENST00000507958.1
CDH18
cadherin 18, type 2
chr3_-_114790179 0.052 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_12290586 0.051 ENST00000379375.5
EDN1
endothelin 1
chr8_-_103876965 0.051 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr17_-_56494908 0.050 ENST00000577716.1
RNF43
ring finger protein 43
chr10_-_73848531 0.050 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_-_111032971 0.050 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chrX_+_102840408 0.050 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4








transcription elongation factor A (SII)-like 4








chr8_+_79428539 0.050 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr1_+_174670143 0.048 ENST00000367687.1
ENST00000347255.2
RABGAP1L

RAB GTPase activating protein 1-like

chr17_-_7307358 0.048 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr9_-_70465758 0.047 ENST00000489273.1
CBWD5
COBW domain containing 5
chr10_-_94257512 0.045 ENST00000371581.5
IDE
insulin-degrading enzyme
chr18_-_47018869 0.045 ENST00000583036.1
ENST00000580261.1
RPL17

ribosomal protein L17

chr21_-_36421401 0.045 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr5_-_13944652 0.045 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chrX_-_103087136 0.044 ENST00000243298.2
RAB9B
RAB9B, member RAS oncogene family
chr15_+_64680003 0.044 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr7_-_102283238 0.043 ENST00000340457.8
UPK3BL
uroplakin 3B-like
chr3_+_159557637 0.043 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr16_+_31128978 0.043 ENST00000448516.2
ENST00000219797.4
KAT8

K(lysine) acetyltransferase 8

chr9_+_116263778 0.042 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr18_-_47018897 0.042 ENST00000418495.1
RPL17
ribosomal protein L17
chr18_-_47018769 0.042 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17





ribosomal protein L17





chr1_+_229440129 0.042 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr9_+_82187630 0.042 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_-_87804815 0.041 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr11_-_31531121 0.040 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr18_-_53019208 0.039 ENST00000562607.1
TCF4
transcription factor 4
chr15_+_80364901 0.039 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6







zinc finger, AN1-type domain 6







chr2_+_58655520 0.038 ENST00000455219.3
ENST00000449448.2
AC007092.1

long intergenic non-protein coding RNA 1122

chr4_+_113568207 0.038 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr3_+_52245458 0.038 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr2_+_211342432 0.038 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr6_-_116833500 0.038 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr12_+_14561422 0.038 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_-_243326612 0.037 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170


centrosomal protein 170kDa


chr8_+_92114873 0.036 ENST00000343709.3
ENST00000448384.2
LRRC69

leucine rich repeat containing 69

chr1_+_70820451 0.036 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3




HERV-H LTR-associating 3




chr1_-_109399682 0.036 ENST00000369995.3
ENST00000370001.3
AKNAD1

AKNA domain containing 1

chr7_+_107224364 0.035 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr21_-_27462351 0.035 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr14_+_76776957 0.034 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr12_+_28410128 0.034 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr7_+_18536090 0.034 ENST00000441986.1
HDAC9
histone deacetylase 9
chr2_+_118572226 0.034 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_+_179318295 0.034 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr14_-_99737565 0.033 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr11_-_8892900 0.033 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5






suppression of tumorigenicity 5






chr1_-_186430222 0.033 ENST00000391997.2
PDC
phosducin
chr3_+_51575596 0.033 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr12_-_6233828 0.033 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr14_+_24407940 0.033 ENST00000354854.1
DHRS4-AS1
DHRS4-AS1
chr12_+_4385230 0.033 ENST00000536537.1
CCND2
cyclin D2
chr7_-_102184083 0.032 ENST00000379357.5
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr7_-_92146729 0.032 ENST00000541751.1
PEX1
peroxisomal biogenesis factor 1
chr15_+_49715293 0.032 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr12_-_76462713 0.031 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr9_-_4666421 0.030 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr3_+_159943362 0.030 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr6_-_74231444 0.029 ENST00000331523.2
ENST00000356303.2
EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr2_-_228244013 0.028 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr1_+_115397424 0.028 ENST00000369522.3
ENST00000455987.1
SYCP1

synaptonemal complex protein 1

chr2_+_218990428 0.028 ENST00000449014.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr17_+_57232690 0.028 ENST00000262293.4
PRR11
proline rich 11
chr8_+_42873548 0.028 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr9_-_4666337 0.027 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr10_-_100995540 0.027 ENST00000370546.1
ENST00000404542.1
HPSE2

heparanase 2

chr17_+_57233087 0.027 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11


proline rich 11


chr6_+_158733692 0.027 ENST00000367094.2
ENST00000367097.3
TULP4

tubby like protein 4

chr9_-_71869642 0.026 ENST00000600472.1
AL358113.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr1_+_85527987 0.026 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63


WD repeat domain 63


chr5_-_78365437 0.026 ENST00000380311.4
ENST00000540686.1
ENST00000255189.3
DMGDH


dimethylglycine dehydrogenase


chr5_+_68513557 0.025 ENST00000256441.4
MRPS36
mitochondrial ribosomal protein S36
chr14_+_77582905 0.025 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr15_-_42302445 0.024 ENST00000413860.2
PLA2G4E
phospholipase A2, group IVE
chr1_-_89357179 0.023 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B


general transcription factor IIB


chr2_-_136678123 0.022 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr10_-_100995603 0.022 ENST00000370552.3
ENST00000370549.1
HPSE2

heparanase 2

chr7_-_137028534 0.022 ENST00000348225.2
PTN
pleiotrophin
chr2_+_108994466 0.022 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr17_-_57232596 0.022 ENST00000581068.1
ENST00000330137.7
SKA2

spindle and kinetochore associated complex subunit 2

chr5_+_161495038 0.022 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr17_-_57232525 0.022 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2



spindle and kinetochore associated complex subunit 2



chr14_+_101295638 0.021 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr2_+_218989991 0.021 ENST00000453237.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr4_-_87374283 0.021 ENST00000361569.2
MAPK10
mitogen-activated protein kinase 10
chr6_-_64029879 0.021 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr4_-_140201333 0.021 ENST00000398955.1
MGARP
mitochondria-localized glutamic acid-rich protein
chr7_+_123241908 0.021 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15


ankyrin repeat and SOCS box containing 15


chr1_-_174992544 0.021 ENST00000476371.1
MRPS14
mitochondrial ribosomal protein S14
chr10_-_75168071 0.020 ENST00000394847.3
ANXA7
annexin A7
chr22_-_39268308 0.020 ENST00000407418.3
CBX6
chromobox homolog 6
chr3_+_16216137 0.019 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr10_-_115904361 0.019 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118

chr17_-_67057114 0.019 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr6_-_80247105 0.018 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr17_-_67057047 0.017 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9


ATP-binding cassette, sub-family A (ABC1), member 9


chr15_+_93443419 0.017 ENST00000557381.1
ENST00000420239.2
CHD2

chromodomain helicase DNA binding protein 2

chr7_-_137028498 0.017 ENST00000393083.2
PTN
pleiotrophin
chr6_-_80247140 0.017 ENST00000392959.1
ENST00000467898.3
LCA5

Leber congenital amaurosis 5

chr19_+_4402659 0.017 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.7 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.0 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042585 female germ cell nucleus(GO:0001674) germinal vesicle(GO:0042585)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.0 GO:0030305 heparanase activity(GO:0030305)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis