Motif ID: NKX3-2
Z-value: 1.040
Transcription factors associated with NKX3-2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| NKX3-2 | ENSG00000109705.7 | NKX3-2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NKX3-2 | hg19_v2_chr4_-_13546632_13546674 | 0.81 | 8.8e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0006714 | sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224) |
| 0.4 | 2.0 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 0.3 | 1.7 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.3 | 1.0 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.3 | 1.3 | GO:0002399 | MHC class II protein complex assembly(GO:0002399) |
| 0.2 | 3.4 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.2 | 4.4 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 0.6 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.1 | 0.4 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938) |
| 0.1 | 0.4 | GO:0031443 | fast-twitch skeletal muscle fiber contraction(GO:0031443) |
| 0.1 | 1.7 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.1 | 2.0 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.1 | 0.3 | GO:0051040 | regulation of calcium-independent cell-cell adhesion(GO:0051040) |
| 0.1 | 0.3 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.1 | 0.4 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.1 | 0.3 | GO:0000270 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.1 | 1.5 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.1 | 0.5 | GO:0019556 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.1 | 0.2 | GO:0002586 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) |
| 0.1 | 0.3 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 0.1 | 0.3 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 0.1 | 0.2 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 0.1 | 0.2 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.5 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.1 | 0.2 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.1 | 0.4 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.0 | 0.2 | GO:0042247 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 0.0 | 0.4 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.0 | 0.0 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
| 0.0 | 0.4 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.0 | 0.1 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 0.0 | 0.4 | GO:0052405 | negative regulation by host of symbiont molecular function(GO:0052405) |
| 0.0 | 0.3 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.0 | 0.5 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.1 | GO:2000974 | auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.0 | 0.1 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.0 | 0.4 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 0.0 | 0.1 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.0 | 0.6 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.0 | 0.1 | GO:0033037 | polysaccharide localization(GO:0033037) |
| 0.0 | 0.1 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.0 | 0.2 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.0 | 0.3 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.2 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.0 | 0.3 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.0 | 0.2 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.0 | 0.2 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.0 | 0.2 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.0 | 0.5 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.0 | 0.2 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.0 | 0.0 | GO:0052314 | phytoalexin metabolic process(GO:0052314) |
| 0.0 | 0.2 | GO:1904338 | regulation of dopaminergic neuron differentiation(GO:1904338) |
| 0.0 | 0.6 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 0.1 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.7 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 0.6 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 0.1 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.0 | 0.0 | GO:2000866 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
| 0.0 | 0.1 | GO:0006547 | histidine metabolic process(GO:0006547) |
| 0.0 | 0.2 | GO:0075044 | autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071) |
| 0.0 | 0.0 | GO:1903998 | regulation of eating behavior(GO:1903998) |
| 0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.1 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.0 | 0.1 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.0 | 0.1 | GO:1903615 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.0 | 0.2 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.0 | 0.1 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.0 | 0.5 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.2 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.0 | 0.1 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.0 | 0.0 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.0 | 0.1 | GO:0006210 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 0.0 | 0.2 | GO:0009415 | response to water(GO:0009415) |
| 0.0 | 0.1 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 0.0 | 0.1 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 0.4 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.5 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 0.2 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.0 | 0.6 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 0.0 | 0.6 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.0 | 0.1 | GO:0018022 | peptidyl-lysine methylation(GO:0018022) |
| 0.0 | 0.0 | GO:0035640 | exploration behavior(GO:0035640) locomotory exploration behavior(GO:0035641) |
| 0.0 | 0.1 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.0 | 0.1 | GO:2000546 | positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.0 | 0.1 | GO:0061419 | positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.0 | 0.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.1 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.2 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.1 | 0.4 | GO:0043257 | laminin-8 complex(GO:0043257) |
| 0.1 | 0.4 | GO:0071665 | gamma-catenin-TCF7L2 complex(GO:0071665) |
| 0.1 | 1.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.3 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 0.8 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 0.6 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.4 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.1 | 0.3 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 0.1 | 0.3 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.6 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.0 | 0.2 | GO:0031592 | centrosomal corona(GO:0031592) |
| 0.0 | 0.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.2 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.0 | 0.6 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 0.1 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
| 0.0 | 0.2 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.0 | 0.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 0.5 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 0.2 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.0 | 0.3 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.3 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 0.1 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.0 | 2.1 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.2 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 2.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 0.1 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.1 | GO:0047718 | androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718) |
| 0.2 | 2.0 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.2 | 1.5 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.2 | 0.6 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.2 | 0.6 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.2 | 4.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.4 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.1 | 0.2 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.1 | 0.3 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.1 | 0.2 | GO:0017098 | sulfonylurea receptor binding(GO:0017098) |
| 0.1 | 0.5 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.1 | 0.2 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.1 | 0.5 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 0.2 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.1 | 0.4 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.1 | 0.4 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.1 | 0.6 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.3 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.1 | 0.4 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.1 | 0.7 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 0.3 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.0 | 0.1 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
| 0.0 | 1.5 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 0.2 | GO:0022897 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.0 | 0.2 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.0 | 0.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 0.3 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 0.8 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.0 | 0.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 0.2 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.0 | 0.2 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
| 0.0 | 0.2 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.0 | 0.1 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.0 | 0.4 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.0 | 0.1 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.0 | 1.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.5 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.1 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.0 | 0.1 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.0 | 0.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.3 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.2 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.0 | 0.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 0.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.1 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.1 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.0 | 0.6 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.1 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.0 | 0.1 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.1 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.0 | 0.1 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 0.2 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.2 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.1 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.1 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 0.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.1 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 0.1 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.0 | 0.9 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.0 | 0.3 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 2.7 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.9 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 1.3 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 2.4 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.7 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.3 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 0.6 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.4 | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 1.0 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.6 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.4 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.4 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.6 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 2.2 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.4 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.2 | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
