Motif ID: NKX1-2_RAX

Z-value: 0.567

Transcription factors associated with NKX1-2_RAX:

Gene SymbolEntrez IDGene Name
NKX1-2 ENSG00000229544.6 NKX1-2
RAX ENSG00000134438.9 RAX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX1-2hg19_v2_chr10_-_126138622_126138753-0.916.4e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of NKX1-2_RAX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_25865159 1.622 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr12_-_10022735 1.119 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr8_+_92261516 0.642 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr7_-_121944491 0.581 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr2_+_210518057 0.547 ENST00000452717.1
MAP2
microtubule-associated protein 2
chr19_-_36822551 0.544 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr2_+_210517895 0.465 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr9_+_125133315 0.422 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr2_-_190446738 0.395 ENST00000427419.1
ENST00000455320.1
SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr1_+_201979645 0.366 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr4_+_77356248 0.355 ENST00000296043.6
SHROOM3
shroom family member 3
chr6_-_94129244 0.352 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr2_+_191221240 0.351 ENST00000409027.1
ENST00000458193.1
INPP1

inositol polyphosphate-1-phosphatase

chrX_+_77166172 0.306 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr4_-_74486217 0.297 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr11_+_5710919 0.292 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr15_+_94899183 0.287 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr4_-_74486109 0.280 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_+_28261492 0.260 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr6_+_26402517 0.253 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr17_-_40337470 0.252 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr10_-_92681033 0.243 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_+_125132803 0.242 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_+_183853052 0.221 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
EIF2B5


eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa


chr2_+_217524323 0.218 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr3_-_105587879 0.215 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr6_+_26402465 0.210 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr4_+_66536248 0.204 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr3_-_105588231 0.199 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr6_+_26440700 0.198 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr10_+_24755416 0.195 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr11_+_71900703 0.177 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr17_-_27418537 0.174 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr11_+_71900572 0.169 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr16_-_55866997 0.155 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr1_+_62439037 0.153 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr4_-_74486347 0.150 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_34204642 0.146 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr3_-_180397256 0.143 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr7_+_100770328 0.139 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr8_-_30670384 0.137 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr19_-_36822595 0.135 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665


long intergenic non-protein coding RNA 665


chr2_+_112939365 0.128 ENST00000272559.4
FBLN7
fibulin 7
chr13_+_78315348 0.127 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr11_-_121986923 0.125 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr10_+_6779326 0.124 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr8_-_29605625 0.120 ENST00000506121.3
LINC00589
long intergenic non-protein coding RNA 589
chr13_+_78315295 0.118 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr4_-_66536196 0.115 ENST00000511294.1
EPHA5
EPH receptor A5
chr10_-_105845536 0.115 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chrX_-_13835147 0.112 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr11_-_124981475 0.111 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218











transmembrane protein 218











chr16_-_28937027 0.106 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr12_-_23737534 0.098 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr19_+_36239576 0.098 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr12_+_16500599 0.097 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1



microsomal glutathione S-transferase 1



chr8_+_9413410 0.094 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS


tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase


chr9_+_125133467 0.090 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr4_+_26324474 0.089 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_16500571 0.088 ENST00000543076.1
ENST00000396210.3
MGST1

microsomal glutathione S-transferase 1

chr1_-_211307404 0.081 ENST00000367007.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr22_-_28490123 0.081 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr4_-_66536057 0.080 ENST00000273854.3
EPHA5
EPH receptor A5
chr6_-_33663474 0.079 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr5_-_159546396 0.079 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A


PWWP domain containing 2A


chr7_-_87342564 0.075 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr9_+_124329336 0.074 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr16_+_29832634 0.072 ENST00000565164.1
ENST00000570234.1
MVP

major vault protein

chr19_+_37742773 0.071 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5


AC012309.5


chr21_-_37914898 0.069 ENST00000399136.1
CLDN14
claudin 14
chr4_-_103749205 0.069 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_93130311 0.069 ENST00000344636.3
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr4_+_80584903 0.066 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr2_+_187371440 0.064 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr14_-_71276211 0.061 ENST00000381250.4
ENST00000555993.2
MAP3K9

mitogen-activated protein kinase kinase kinase 9

chr16_-_48281444 0.060 ENST00000537808.1
ENST00000569991.1
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr4_-_103749179 0.059 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr19_+_37808831 0.058 ENST00000589801.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr6_+_30687978 0.056 ENST00000327892.8
ENST00000435534.1
TUBB

tubulin, beta class I

chr1_-_190446759 0.056 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_113763031 0.056 ENST00000259211.6
IL36A
interleukin 36, alpha
chr4_-_103749105 0.055 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr2_+_166095898 0.051 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A


sodium channel, voltage-gated, type II, alpha subunit


chr3_+_195447738 0.051 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chr2_+_149402989 0.048 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr4_-_103749313 0.048 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_-_102898465 0.047 ENST00000507423.1
ENST00000230792.2
NUDT12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr2_-_239197201 0.044 ENST00000254658.3
PER2
period circadian clock 2
chr9_+_135937365 0.043 ENST00000372080.4
ENST00000351304.7
CEL

carboxyl ester lipase

chr12_+_64798826 0.043 ENST00000540203.1
XPOT
exportin, tRNA
chr8_-_135522425 0.043 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr2_-_239197238 0.043 ENST00000254657.3
PER2
period circadian clock 2
chr18_+_22040593 0.041 ENST00000256906.4
HRH4
histamine receptor H4
chr11_-_59383617 0.040 ENST00000263847.1
OSBP
oxysterol binding protein
chr17_-_41466555 0.040 ENST00000586231.1
LINC00910
long intergenic non-protein coding RNA 910
chr14_-_88200641 0.040 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr4_-_103748880 0.039 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr2_-_198540719 0.038 ENST00000295049.4
RFTN2
raftlin family member 2
chr9_-_95166841 0.037 ENST00000262551.4
OGN
osteoglycin
chr4_+_110736659 0.035 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chr7_-_7575477 0.035 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr11_+_118398178 0.033 ENST00000302783.4
ENST00000539546.1
TTC36

tetratricopeptide repeat domain 36

chrX_+_77154935 0.033 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr4_-_10686475 0.032 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr8_-_112248400 0.031 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4

RP11-946L20.4

chr12_+_7013897 0.031 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr11_-_62521614 0.031 ENST00000527994.1
ENST00000394807.3
ZBTB3

zinc finger and BTB domain containing 3

chr10_+_35894338 0.030 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr16_-_28608424 0.029 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr11_-_63376013 0.028 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr1_-_28969517 0.028 ENST00000263974.4
ENST00000373824.4
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr11_+_33061543 0.026 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr11_+_22689648 0.026 ENST00000278187.3
GAS2
growth arrest-specific 2
chr16_-_48281305 0.025 ENST00000356608.2
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr19_-_46285736 0.024 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chr4_-_89442940 0.024 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr6_+_26501449 0.023 ENST00000244513.6
BTN1A1
butyrophilin, subfamily 1, member A1
chr1_+_100818156 0.023 ENST00000336454.3
CDC14A
cell division cycle 14A
chr20_-_1447547 0.022 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr17_-_4938712 0.022 ENST00000254853.5
ENST00000424747.1
SLC52A1

solute carrier family 52 (riboflavin transporter), member 1

chr2_-_220264703 0.022 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP



aspartyl aminopeptidase



chr12_+_90674665 0.022 ENST00000549313.1
RP11-753N8.1
RP11-753N8.1
chr1_+_100818009 0.021 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A


cell division cycle 14A


chr3_-_191000172 0.020 ENST00000427544.2
UTS2B
urotensin 2B
chr17_-_45266542 0.020 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27




cell division cycle 27




chr16_-_28608364 0.019 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr3_+_28390637 0.019 ENST00000420223.1
ENST00000383768.2
ZCWPW2

zinc finger, CW type with PWWP domain 2

chr14_+_55493920 0.019 ENST00000395472.2
ENST00000555846.1
SOCS4

suppressor of cytokine signaling 4

chrX_+_107288280 0.018 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr20_-_1447467 0.017 ENST00000353088.2
ENST00000350991.4
NSFL1C

NSFL1 (p97) cofactor (p47)

chr12_-_50790267 0.016 ENST00000327337.5
ENST00000543111.1
FAM186A

family with sequence similarity 186, member A

chr21_-_35796241 0.016 ENST00000450895.1
AP000322.53
AP000322.53
chr1_-_224624730 0.016 ENST00000445239.1
WDR26
WD repeat domain 26
chr14_+_103851712 0.015 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3



MAP/microtubule affinity-regulating kinase 3



chr7_+_50348268 0.014 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr2_+_105050794 0.013 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2


long intergenic non-protein coding RNA 1102


chr3_+_186560476 0.012 ENST00000320741.2
ENST00000444204.2
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr14_+_55494323 0.012 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr17_-_33390667 0.012 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr20_+_43990576 0.010 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr3_+_186560462 0.010 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr15_+_51669513 0.010 ENST00000558426.1
GLDN
gliomedin
chr10_+_99205959 0.009 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16



zinc finger, DHHC-type containing 16



chr7_-_37488547 0.008 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr3_+_45986511 0.008 ENST00000458629.1
ENST00000457814.1
CXCR6

chemokine (C-X-C motif) receptor 6

chr2_+_24714729 0.007 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr9_-_95166976 0.006 ENST00000447356.1
OGN
osteoglycin
chr15_-_43882140 0.006 ENST00000429176.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr5_+_150226085 0.006 ENST00000522154.1
IRGM
immunity-related GTPase family, M
chr11_-_3859089 0.005 ENST00000396979.1
RHOG
ras homolog family member G
chr7_-_99717463 0.004 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_+_29181503 0.004 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chr10_+_99205894 0.004 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16



zinc finger, DHHC-type containing 16



chr7_-_99716940 0.004 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_-_74686314 0.004 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2


RP11-81H3.2


chr6_+_52442083 0.003 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr11_-_74800799 0.003 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr12_+_7014064 0.002 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr1_-_17766198 0.002 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr4_-_175041663 0.002 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr10_+_18549645 0.001 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_42523336 0.001 ENST00000428529.1
RP5-1030M6.3
RP5-1030M6.3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.4 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.4 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1900920 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection