Motif ID: NFKB1

Z-value: 0.325


Transcription factors associated with NFKB1:

Gene SymbolEntrez IDGene Name
NFKB1 ENSG00000109320.7 NFKB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFKB1hg19_v2_chr4_+_103422499_1034226320.665.4e-02Click!


Activity profile for motif NFKB1.

activity profile for motif NFKB1


Sorted Z-values histogram for motif NFKB1

Sorted Z-values for motif NFKB1



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_138304939 0.378 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr5_+_82767284 0.318 ENST00000265077.3
VCAN
versican
chr12_-_55375622 0.283 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr12_+_52445191 0.267 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr12_-_132905789 0.262 ENST00000328957.8
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr14_-_103589246 0.256 ENST00000558224.1
ENST00000560742.1
LINC00677

long intergenic non-protein coding RNA 677

chr10_+_99609996 0.234 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr6_+_12749657 0.226 ENST00000406205.2
PHACTR1
phosphatase and actin regulator 1
chr14_+_52313833 0.212 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr9_-_117568365 0.212 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chrX_-_112084043 0.211 ENST00000304758.1
AMOT
angiomotin
chr4_-_74864386 0.198 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr14_-_75078725 0.193 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr4_+_74735102 0.184 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr12_+_52431016 0.183 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr8_+_104831472 0.182 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chr1_-_166135952 0.178 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr19_+_51728316 0.173 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr5_-_138842286 0.166 ENST00000515823.1
ECSCR
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr12_+_52430894 0.164 ENST00000546842.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr1_+_86064794 0.163 ENST00000426794.1
RP11-290M5.2
RP11-290M5.2
chr6_+_138188378 0.159 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_-_46145696 0.150 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr6_-_31550192 0.150 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr8_+_104831554 0.149 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr9_+_82188077 0.147 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_+_138188551 0.145 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr10_+_104154229 0.136 ENST00000428099.1
ENST00000369966.3
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr20_+_44746885 0.136 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr3_-_111852128 0.135 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr19_+_48898132 0.134 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr20_+_6748311 0.132 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr1_-_206671061 0.128 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr2_-_74669009 0.124 ENST00000272430.5
RTKN
rhotekin
chr1_+_243419306 0.124 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr16_-_77468945 0.117 ENST00000282849.5
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr1_-_161279749 0.117 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ


myelin protein zero


chr2_+_29001711 0.116 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr14_+_75988768 0.116 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr17_-_39968406 0.115 ENST00000393928.1
LEPREL4
leprecan-like 4
chr2_-_74782817 0.114 ENST00000413469.1
LOXL3
lysyl oxidase-like 3
chrX_-_21776281 0.113 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr17_-_7590745 0.111 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr3_-_111852061 0.109 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM



germinal center-associated, signaling and motility



chr1_-_8000872 0.108 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr3_+_53195136 0.107 ENST00000394729.2
ENST00000330452.3
PRKCD

protein kinase C, delta

chr20_+_44746939 0.106 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr1_+_186649754 0.105 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr17_-_7108436 0.102 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr15_-_66084621 0.101 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr17_-_7123021 0.099 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr18_-_72920372 0.099 ENST00000581620.1
ENST00000582437.1
ZADH2

zinc binding alcohol dehydrogenase domain containing 2

chr14_+_24521202 0.097 ENST00000334420.7
ENST00000342740.5
LRRC16B

leucine rich repeat containing 16B

chr5_+_54603566 0.096 ENST00000230640.5
SKIV2L2
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
chr11_-_64570706 0.094 ENST00000294066.2
ENST00000377350.3
MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

chr11_-_61596753 0.092 ENST00000448607.1
ENST00000421879.1
FADS1

fatty acid desaturase 1

chr6_+_106534192 0.092 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr2_+_97202480 0.092 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr19_+_42381173 0.090 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr2_+_97203082 0.089 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr17_-_77179487 0.088 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr1_+_11539204 0.088 ENST00000294484.6
ENST00000389575.3
PTCHD2

patched domain containing 2

chr17_-_61777090 0.088 ENST00000578061.1
LIMD2
LIM domain containing 2
chr17_+_4854375 0.087 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3




enolase 3 (beta, muscle)




chr6_+_138188351 0.086 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr9_-_136344197 0.084 ENST00000414172.1
ENST00000371897.4
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr17_-_61776522 0.082 ENST00000582055.1
LIMD2
LIM domain containing 2
chr14_+_96342729 0.080 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr14_+_96343100 0.078 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr5_-_43313269 0.078 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_+_163175394 0.078 ENST00000446271.1
ENST00000429691.2
GCA

grancalcin, EF-hand calcium binding protein

chr19_+_10527449 0.076 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr19_+_45504688 0.075 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr11_-_64570624 0.074 ENST00000439069.1
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr6_+_32821924 0.072 ENST00000374859.2
ENST00000453265.2
PSMB9

proteasome (prosome, macropain) subunit, beta type, 9

chr1_+_45274154 0.071 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr17_+_17685422 0.071 ENST00000395774.1
RAI1
retinoic acid induced 1
chr11_-_6426635 0.070 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1


amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)


chr17_-_17740287 0.070 ENST00000355815.4
ENST00000261646.5
SREBF1

sterol regulatory element binding transcription factor 1

chr1_+_37940153 0.069 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr4_+_142557771 0.069 ENST00000514653.1
IL15
interleukin 15
chr17_+_74381343 0.069 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr4_-_74904398 0.069 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr3_+_57261743 0.069 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr4_+_142558078 0.069 ENST00000529613.1
IL15
interleukin 15
chr16_+_67282853 0.068 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chrX_-_38080077 0.067 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX



sushi-repeat containing protein, X-linked



chr11_-_72853267 0.066 ENST00000409418.4
FCHSD2
FCH and double SH3 domains 2
chr12_-_62997214 0.066 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr11_-_133826852 0.065 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr12_-_58131931 0.065 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_-_54468974 0.064 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B




cell division cycle 20B




chr1_-_202129704 0.064 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7








protein tyrosine phosphatase, non-receptor type 7








chr15_+_85923797 0.063 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr7_+_143013198 0.063 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr19_+_55795493 0.062 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr3_+_57261859 0.062 ENST00000495803.1
ENST00000444459.1
APPL1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

chr14_+_75988851 0.062 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr17_+_2264983 0.062 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr12_-_121972556 0.062 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr19_-_49149553 0.062 ENST00000084798.4
CA11
carbonic anhydrase XI
chr1_-_156051789 0.062 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr2_+_74212073 0.061 ENST00000441217.1
AC073046.25
AC073046.25
chr16_+_88636789 0.061 ENST00000301011.5
ENST00000452588.2
ZC3H18

zinc finger CCCH-type containing 18

chr1_-_202130702 0.060 ENST00000309017.3
ENST00000477554.1
ENST00000492451.1
PTPN7


protein tyrosine phosphatase, non-receptor type 7


chr11_-_47400062 0.059 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr10_+_89419370 0.059 ENST00000361175.4
ENST00000456849.1
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr3_-_156878540 0.058 ENST00000461804.1
CCNL1
cyclin L1
chr19_+_41860047 0.056 ENST00000604123.1
TMEM91
transmembrane protein 91
chr17_+_79373540 0.056 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr19_-_13617247 0.056 ENST00000573710.2
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr9_+_82187487 0.056 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chr11_+_19799327 0.055 ENST00000540292.1
NAV2
neuron navigator 2
chr4_-_185395191 0.055 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2


interferon regulatory factor 2


chr6_-_111804905 0.055 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr10_+_89124746 0.055 ENST00000465545.1
NUTM2D
NUT family member 2D
chr19_-_41222775 0.055 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4


aarF domain containing kinase 4


chr4_+_103422499 0.054 ENST00000511926.1
ENST00000507079.1
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr15_-_89438742 0.054 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3


hyaluronan and proteoglycan link protein 3


chr4_-_185395672 0.054 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr6_+_80341000 0.053 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr4_+_103422471 0.053 ENST00000226574.4
ENST00000394820.4
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr2_-_86790593 0.052 ENST00000263856.4
ENST00000409225.2
CHMP3

charged multivesicular body protein 3

chr3_+_159557637 0.052 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr3_-_156878482 0.052 ENST00000295925.4
CCNL1
cyclin L1
chr19_+_17638059 0.052 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C



family with sequence similarity 129, member C



chr19_-_5785630 0.051 ENST00000590343.1
ENST00000586012.1
DUS3L
CTB-54O9.9
dihydrouridine synthase 3-like (S. cerevisiae)
Uncharacterized protein
chr7_-_155601766 0.051 ENST00000430104.1
SHH
sonic hedgehog
chr2_-_86790472 0.050 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr11_-_47399942 0.050 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_+_31540056 0.049 ENST00000418386.2
LTA
lymphotoxin alpha
chr14_-_23762777 0.048 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr12_-_28124903 0.048 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr11_+_118754475 0.048 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr11_-_77185094 0.047 ENST00000278568.4
ENST00000356341.3
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr4_-_140098339 0.047 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_-_6591113 0.047 ENST00000423145.3
ENST00000245903.3
CD70

CD70 molecule

chr11_+_19798964 0.047 ENST00000527559.2
NAV2
neuron navigator 2
chr2_-_100721178 0.046 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr6_-_88299678 0.046 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr11_-_44331679 0.046 ENST00000329255.3
ALX4
ALX homeobox 4
chr1_-_173886491 0.046 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr15_-_66084428 0.046 ENST00000443035.3
ENST00000431932.2
DENND4A

DENN/MADD domain containing 4A

chr16_+_88636875 0.046 ENST00000569435.1
ZC3H18
zinc finger CCCH-type containing 18
chr4_-_5890145 0.046 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr6_-_74230741 0.046 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chrX_+_117861535 0.046 ENST00000371666.3
ENST00000371642.1
IL13RA1

interleukin 13 receptor, alpha 1

chr20_-_62462566 0.046 ENST00000245663.4
ENST00000302995.2
ZBTB46

zinc finger and BTB domain containing 46

chr12_+_6875519 0.045 ENST00000389462.4
ENST00000540874.1
ENST00000309083.6
PTMS


parathymosin


chr5_-_78365437 0.045 ENST00000380311.4
ENST00000540686.1
ENST00000255189.3
DMGDH


dimethylglycine dehydrogenase


chrX_-_9754333 0.045 ENST00000447366.1
GPR143
G protein-coupled receptor 143
chr1_+_221054584 0.045 ENST00000549319.1
HLX
H2.0-like homeobox
chr6_-_74231303 0.045 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_72525353 0.045 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2


autophagy related 16-like 2 (S. cerevisiae)


chr15_+_33010175 0.044 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1


gremlin 1, DAN family BMP antagonist


chr12_-_12849073 0.044 ENST00000332427.2
ENST00000540796.1
GPR19

G protein-coupled receptor 19

chr18_-_72921303 0.044 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr7_-_127032741 0.044 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800


zinc finger protein 800


chr1_-_153935983 0.044 ENST00000537590.1
ENST00000356205.4
SLC39A1

solute carrier family 39 (zinc transporter), member 1

chr11_-_47400078 0.043 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr17_+_40440481 0.043 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr13_-_30424821 0.043 ENST00000380680.4
UBL3
ubiquitin-like 3
chr13_-_107214291 0.042 ENST00000375926.1
ARGLU1
arginine and glutamate rich 1
chr15_+_85923856 0.042 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13



A kinase (PRKA) anchor protein 13



chr1_-_153935791 0.042 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr11_-_72853091 0.042 ENST00000311172.7
ENST00000409314.1
FCHSD2

FCH and double SH3 domains 2

chr11_+_124481361 0.041 ENST00000284288.2
PANX3
pannexin 3
chr7_+_120629653 0.041 ENST00000450913.2
ENST00000340646.5
CPED1

cadherin-like and PC-esterase domain containing 1

chr2_+_68694678 0.041 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr17_+_7123125 0.041 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL


acyl-CoA dehydrogenase, very long chain


chr17_+_7123207 0.041 ENST00000584103.1
ENST00000579886.2
ACADVL

acyl-CoA dehydrogenase, very long chain

chr3_+_157154578 0.040 ENST00000295927.3
PTX3
pentraxin 3, long
chr9_+_82187630 0.040 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_-_100721923 0.040 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr1_-_153935938 0.040 ENST00000368621.1
ENST00000368623.3
SLC39A1

solute carrier family 39 (zinc transporter), member 1

chr10_-_29923893 0.040 ENST00000355867.4
SVIL
supervillin
chr2_+_64681641 0.040 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr19_+_17638041 0.039 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr6_-_74231444 0.039 ENST00000331523.2
ENST00000356303.2
EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr11_+_94706804 0.039 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr4_-_147442982 0.038 ENST00000511374.1
ENST00000264986.3
SLC10A7

solute carrier family 10, member 7

chr14_-_21852119 0.038 ENST00000555943.1
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr3_+_101546827 0.038 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr5_-_150521192 0.038 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr16_+_57126482 0.038 ENST00000537605.1
ENST00000535318.2
CPNE2

copine II

chr17_+_4802713 0.038 ENST00000521575.1
ENST00000381365.3
C17orf107

chromosome 17 open reading frame 107

chr15_+_22892663 0.037 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1


cytoplasmic FMR1 interacting protein 1


chr1_-_65432171 0.037 ENST00000342505.4
JAK1
Janus kinase 1
chr11_-_72852958 0.037 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr16_+_57126428 0.037 ENST00000290776.8
CPNE2
copine II
chr1_-_153935738 0.036 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr19_-_13617037 0.036 ENST00000360228.5
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr1_+_155657737 0.035 ENST00000471642.2
ENST00000471214.1
DAP3

death associated protein 3

chr11_+_94706973 0.035 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr12_+_50690489 0.035 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr19_+_42381337 0.035 ENST00000597454.1
ENST00000444740.2
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr22_+_20748405 0.034 ENST00000400451.2
ENST00000403682.3
ENST00000357502.5
ZNF74


zinc finger protein 74


chr11_-_66313699 0.034 ENST00000526986.1
ENST00000310442.3
ZDHHC24

zinc finger, DHHC-type containing 24

chr1_-_146644122 0.034 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr17_-_4852332 0.034 ENST00000572383.1
PFN1
profilin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.1 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.2 GO:0036018 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.1 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.0 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:1900169 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:0002925 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.0 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.0 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.0 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.0 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:2000466 negative regulation of glycogen (starch) synthase activity(GO:2000466) regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0001878 response to yeast(GO:0001878)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.0 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.0 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.0 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation