Motif ID: NFE2L1

Z-value: 0.872


Transcription factors associated with NFE2L1:

Gene SymbolEntrez IDGene Name
NFE2L1 ENSG00000082641.11 NFE2L1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46125685_461256990.809.4e-03Click!


Activity profile for motif NFE2L1.

activity profile for motif NFE2L1


Sorted Z-values histogram for motif NFE2L1

Sorted Z-values for motif NFE2L1



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_121944491 1.930 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr8_-_18942240 0.801 ENST00000521475.1
PSD3
pleckstrin and Sec7 domain containing 3
chr21_+_36041688 0.784 ENST00000360731.3
ENST00000349499.2
CLIC6

chloride intracellular channel 6

chr1_+_171060018 0.729 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
FMO3




flavin containing monooxygenase 3




chr6_+_117586713 0.722 ENST00000352536.3
ENST00000326274.5
VGLL2

vestigial like 2 (Drosophila)

chr6_-_33037019 0.683 ENST00000437811.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr6_+_33043703 0.622 ENST00000418931.2
ENST00000535465.1
HLA-DPB1

major histocompatibility complex, class II, DP beta 1

chr4_+_75858318 0.620 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr3_-_171489085 0.598 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr2_-_207078086 0.555 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr8_-_30706608 0.517 ENST00000256246.2
TEX15
testis expressed 15
chr16_+_19467772 0.487 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5


transmembrane channel-like 5


chr5_+_36608422 0.480 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_169013666 0.460 ENST00000359299.3
ANXA10
annexin A10
chr1_+_82165350 0.453 ENST00000359929.3
LPHN2
latrophilin 2
chr2_-_145188137 0.450 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_46048116 0.415 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr2_+_102721023 0.415 ENST00000409589.1
ENST00000409329.1
IL1R1

interleukin 1 receptor, type I

chr5_+_173763250 0.406 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1


RP11-267A15.1


chr1_+_43613566 0.406 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr22_-_36013368 0.402 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr4_-_819901 0.400 ENST00000304062.6
CPLX1
complexin 1
chr15_-_88247083 0.395 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chr4_-_48116540 0.366 ENST00000506073.1
TXK
TXK tyrosine kinase
chr2_+_169926047 0.360 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr7_-_142198049 0.353 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr4_-_819880 0.352 ENST00000505203.1
CPLX1
complexin 1
chr8_-_120651020 0.352 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr19_+_36203830 0.349 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr9_-_39239171 0.342 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr2_-_70781087 0.338 ENST00000394241.3
ENST00000295400.6
TGFA

transforming growth factor, alpha

chrX_+_9754461 0.332 ENST00000380913.3
SHROOM2
shroom family member 2
chr2_-_207078154 0.331 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr1_-_31661000 0.318 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1


Na+/K+ transporting ATPase interacting 1


chr10_-_24770632 0.317 ENST00000596413.1
AL353583.1
AL353583.1
chr15_+_94899183 0.315 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr6_-_52109335 0.315 ENST00000336123.4
IL17F
interleukin 17F
chr19_-_43383789 0.315 ENST00000595356.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr1_-_39395165 0.309 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr9_+_1051481 0.309 ENST00000358146.2
ENST00000259622.6
DMRT2

doublesex and mab-3 related transcription factor 2

chr4_-_52883786 0.308 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr2_-_158345462 0.302 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr6_+_27114861 0.302 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr2_+_182850551 0.300 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr9_-_119162885 0.299 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr1_+_43613612 0.295 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr14_+_62462541 0.291 ENST00000430451.2
SYT16
synaptotagmin XVI
chr1_+_180875711 0.285 ENST00000434447.1
RP11-46A10.2
RP11-46A10.2
chr19_-_49843539 0.274 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4

CTC-301O7.4

chr1_-_232651312 0.270 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr6_+_153019069 0.268 ENST00000532295.1
MYCT1
myc target 1
chr18_+_32455201 0.263 ENST00000590831.2
DTNA
dystrobrevin, alpha
chrX_-_13835461 0.260 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr5_+_173930676 0.256 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr11_-_74408739 0.251 ENST00000529912.1
CHRDL2
chordin-like 2
chr6_-_56507586 0.251 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST




dystonin




chr2_+_169923577 0.251 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr2_+_182850743 0.249 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr3_+_69928256 0.248 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr15_-_54267147 0.247 ENST00000558866.1
ENST00000558920.1
RP11-643A5.2

RP11-643A5.2

chr4_-_159080806 0.240 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr3_-_186262166 0.233 ENST00000307944.5
CRYGS
crystallin, gamma S
chr8_-_27472198 0.233 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU




clusterin




chr4_-_40632605 0.232 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr8_-_33455268 0.231 ENST00000522982.1
DUSP26
dual specificity phosphatase 26 (putative)
chr12_-_53228079 0.230 ENST00000330553.5
KRT79
keratin 79
chr3_+_187957646 0.230 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_183538319 0.228 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr8_-_18744528 0.226 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr10_+_115511434 0.223 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr17_-_29645836 0.222 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr2_+_113763031 0.219 ENST00000259211.6
IL36A
interleukin 36, alpha
chr11_+_71903169 0.216 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr18_+_32398326 0.216 ENST00000269192.7
ENST00000591182.1
ENST00000597674.1
ENST00000556414.3
DTNA



dystrobrevin, alpha



chr6_+_41021027 0.210 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr9_-_97356075 0.206 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr2_-_205099700 0.206 ENST00000419860.1
AC009498.1
AC009498.1
chr6_-_31107127 0.204 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr2_+_233271546 0.204 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr2_+_169923504 0.203 ENST00000357546.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr11_-_10920714 0.198 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr19_-_36545649 0.195 ENST00000292894.1
THAP8
THAP domain containing 8
chr2_-_228579305 0.193 ENST00000456524.1
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr10_-_128975273 0.193 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr17_+_73606766 0.193 ENST00000578462.1
MYO15B
myosin XVB pseudogene
chr14_-_92247032 0.193 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB


catsper channel auxiliary subunit beta


chr18_-_2982869 0.188 ENST00000584915.1
LPIN2
lipin 2
chr9_+_92219919 0.185 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr1_+_170115142 0.183 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr4_-_40632757 0.183 ENST00000511902.1
ENST00000505220.1
RBM47

RNA binding motif protein 47

chr8_-_124665190 0.182 ENST00000325995.7
KLHL38
kelch-like family member 38
chr17_+_42264395 0.182 ENST00000587989.1
ENST00000590235.1
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr1_-_11865982 0.181 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr2_+_169658928 0.181 ENST00000317647.7
ENST00000445023.2
NOSTRIN

nitric oxide synthase trafficking

chr8_+_22853345 0.177 ENST00000522948.1
RHOBTB2
Rho-related BTB domain containing 2
chr8_-_7287870 0.176 ENST00000318124.3
DEFB103B
defensin, beta 103B
chr8_+_7738726 0.174 ENST00000314357.3
DEFB103A
defensin, beta 103A
chr7_-_142247606 0.172 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr8_+_24151553 0.172 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chr4_-_83931862 0.170 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54



lin-54 homolog (C. elegans)



chr1_+_6845384 0.168 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr2_-_106015527 0.168 ENST00000344213.4
ENST00000358129.4
FHL2

four and a half LIM domains 2

chr5_+_36608280 0.168 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_139055055 0.165 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr5_+_173930710 0.165 ENST00000511707.1
RP11-267A15.1
RP11-267A15.1
chr12_+_41086297 0.165 ENST00000551295.2
CNTN1
contactin 1
chr1_-_241799232 0.165 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr6_-_152623231 0.162 ENST00000540663.1
ENST00000537033.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr11_-_119991589 0.160 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr4_-_40632844 0.157 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr2_-_25451065 0.155 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr9_-_124976185 0.155 ENST00000464484.2
LHX6
LIM homeobox 6
chr7_-_142224280 0.152 ENST00000390367.3
TRBV11-1
T cell receptor beta variable 11-1
chr12_-_18890940 0.152 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1





phospholipase C, zeta 1





chr3_+_63638339 0.151 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr1_-_11866034 0.149 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_28586006 0.148 ENST00000253063.3
SESN2
sestrin 2
chr5_+_109218883 0.146 ENST00000523446.1
AC011366.3
Uncharacterized protein
chr14_+_21492331 0.145 ENST00000533984.1
ENST00000532213.2
AL161668.5

AL161668.5

chr11_+_35211511 0.145 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr8_-_29592736 0.145 ENST00000518623.1
LINC00589
long intergenic non-protein coding RNA 589
chr11_+_57308979 0.143 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr12_-_105352080 0.143 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr8_-_13372395 0.143 ENST00000276297.4
ENST00000511869.1
DLC1

deleted in liver cancer 1

chr6_+_116937636 0.141 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr11_+_74811578 0.140 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr3_-_98241358 0.137 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1



claudin domain containing 1



chr4_+_4861385 0.137 ENST00000382723.4
MSX1
msh homeobox 1
chr2_-_106015491 0.136 ENST00000408995.1
ENST00000393353.3
ENST00000322142.8
FHL2


four and a half LIM domains 2


chr11_-_82708435 0.136 ENST00000525117.1
ENST00000532548.1
RAB30

RAB30, member RAS oncogene family

chr3_-_98241598 0.136 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1



claudin domain containing 1



chr7_+_116312411 0.135 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr3_+_107096188 0.134 ENST00000261058.1
CCDC54
coiled-coil domain containing 54
chr17_+_28256874 0.134 ENST00000541045.1
ENST00000536908.2
EFCAB5

EF-hand calcium binding domain 5

chr1_-_156265438 0.133 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chrX_-_48814278 0.132 ENST00000455452.1
OTUD5
OTU domain containing 5
chr16_+_28996114 0.130 ENST00000395461.3
LAT
linker for activation of T cells
chr19_-_36019123 0.128 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr4_+_71494461 0.128 ENST00000396073.3
ENAM
enamelin
chr6_+_33378738 0.128 ENST00000374512.3
ENST00000374516.3
PHF1

PHD finger protein 1

chrX_-_13835147 0.127 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr12_-_65146717 0.127 ENST00000545273.1
GNS
glucosamine (N-acetyl)-6-sulfatase
chr2_+_149974684 0.126 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr4_-_40632881 0.126 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr3_-_143567262 0.125 ENST00000474151.1
ENST00000316549.6
SLC9A9

solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9

chr22_-_28490123 0.124 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr6_+_31939608 0.124 ENST00000375331.2
ENST00000375333.2
STK19

serine/threonine kinase 19

chr12_+_22778291 0.123 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr16_+_31044413 0.123 ENST00000394998.1
STX4
syntaxin 4
chr2_+_48796120 0.122 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr6_+_30539153 0.122 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1




ATP-binding cassette, sub-family F (GCN20), member 1




chr11_-_87908600 0.122 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38


RAB38, member RAS oncogene family


chr3_-_110612323 0.121 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chrX_+_49126294 0.118 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F



protein phosphatase 1, regulatory subunit 3F



chr17_-_65992544 0.118 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr11_-_85397167 0.118 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr11_+_128563652 0.118 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_38375528 0.117 ENST00000583268.1
WIPF2
WAS/WASL interacting protein family, member 2
chr8_+_55528627 0.116 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr5_+_139055021 0.115 ENST00000502716.1
ENST00000503511.1
CXXC5

CXXC finger protein 5

chr7_+_141463897 0.113 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr16_+_28996364 0.113 ENST00000564277.1
LAT
linker for activation of T cells
chr17_+_42264322 0.113 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
TMUB2


transmembrane and ubiquitin-like domain containing 2


chr12_-_105352047 0.112 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
SLC41A2


solute carrier family 41 (magnesium transporter), member 2


chr6_-_154751629 0.111 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr15_-_43559055 0.110 ENST00000220420.5
ENST00000349114.4
TGM5

transglutaminase 5

chr17_-_53800217 0.110 ENST00000424486.2
TMEM100
transmembrane protein 100
chr2_-_224467093 0.109 ENST00000305409.2
SCG2
secretogranin II
chr9_-_104198042 0.109 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr3_+_69812877 0.109 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr11_-_82708519 0.108 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr2_-_197675000 0.108 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr16_-_69760409 0.108 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1




NAD(P)H dehydrogenase, quinone 1




chr17_+_28268623 0.108 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5



EF-hand calcium binding domain 5



chr9_-_117692697 0.108 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr7_-_115608304 0.107 ENST00000457268.1
TFEC
transcription factor EC
chr1_-_53608249 0.107 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr1_+_11866207 0.107 ENST00000312413.6
ENST00000346436.6
CLCN6

chloride channel, voltage-sensitive 6

chr9_+_35042205 0.107 ENST00000312292.5
ENST00000378745.3
C9orf131

chromosome 9 open reading frame 131

chr2_-_197458271 0.106 ENST00000427457.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr6_-_31940065 0.106 ENST00000375349.3
ENST00000337523.5
DXO

decapping exoribonuclease

chr15_+_45406519 0.106 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr16_+_31044812 0.105 ENST00000313843.3
STX4
syntaxin 4
chr17_-_33905521 0.104 ENST00000225873.4
PEX12
peroxisomal biogenesis factor 12
chrX_-_48827976 0.104 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr3_-_46786245 0.102 ENST00000442359.2
PRSS45
protease, serine, 45
chr17_-_29648761 0.102 ENST00000247270.3
ENST00000462804.2
EVI2A

ecotropic viral integration site 2A

chr4_+_90033968 0.101 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr15_-_81202118 0.101 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr14_+_23790655 0.101 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr17_+_30348024 0.101 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
LRRC37B



leucine rich repeat containing 37B



chr7_-_139477500 0.101 ENST00000406875.3
ENST00000428878.2
HIPK2

homeodomain interacting protein kinase 2

chr4_+_166300084 0.100 ENST00000402744.4
CPE
carboxypeptidase E
chr12_-_65146636 0.100 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr12_+_48147699 0.100 ENST00000548498.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr8_+_67039278 0.099 ENST00000276573.7
ENST00000350034.4
TRIM55

tripartite motif containing 55

chr11_+_123986069 0.099 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A





von Willebrand factor A domain containing 5A





chr17_+_42264556 0.099 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2



transmembrane and ubiquitin-like domain containing 2



chr9_-_95166884 0.097 ENST00000375561.5
OGN
osteoglycin
chr3_-_98241713 0.097 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
CLDND1




claudin domain containing 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.5 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.3 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0048850 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0002586 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of adrenergic receptor signaling pathway(GO:0071878) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.0 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.2 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.0 GO:0043132 NAD transport(GO:0043132)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.9 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.0 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE