Motif ID: NFATC4

Z-value: 0.474


Transcription factors associated with NFATC4:

Gene SymbolEntrez IDGene Name
NFATC4 ENSG00000100968.9 NFATC4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFATC4hg19_v2_chr14_+_24837226_24837547-0.693.9e-02Click!


Activity profile for motif NFATC4.

activity profile for motif NFATC4


Sorted Z-values histogram for motif NFATC4

Sorted Z-values for motif NFATC4



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_121944491 1.120 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr9_+_706842 0.663 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr6_-_47010061 0.503 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr12_-_10007448 0.488 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chrX_-_43741594 0.472 ENST00000536181.1
ENST00000378069.4
MAOB

monoamine oxidase B

chr3_+_98250743 0.461 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr2_-_207078086 0.455 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr12_-_71551652 0.437 ENST00000546561.1
TSPAN8
tetraspanin 8
chr1_+_11714425 0.422 ENST00000251546.4
FBXO44
F-box protein 44
chr18_+_52385068 0.414 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr5_-_88179017 0.367 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
MEF2C



myocyte enhancer factor 2C



chr5_-_88178964 0.344 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
MEF2C



myocyte enhancer factor 2C



chr10_+_70980051 0.327 ENST00000354624.5
ENST00000395086.2
HKDC1

hexokinase domain containing 1

chr20_+_12989822 0.322 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr8_-_19459993 0.320 ENST00000454498.2
ENST00000520003.1
CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr2_-_145188137 0.319 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr20_+_12989596 0.318 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr11_+_62475130 0.306 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr1_+_82266053 0.298 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr1_-_57045228 0.290 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_31885963 0.288 ENST00000373709.3
SERINC2
serine incorporator 2
chr8_+_17434689 0.278 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr6_-_26056695 0.274 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr8_-_110703819 0.272 ENST00000532779.1
ENST00000534578.1
SYBU

syntabulin (syntaxin-interacting)

chr17_-_39942322 0.263 ENST00000449889.1
ENST00000465293.1
JUP

junction plakoglobin

chr1_+_164528866 0.251 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr14_+_88471468 0.249 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr1_-_151826173 0.248 ENST00000368817.5
THEM5
thioesterase superfamily member 5
chr8_-_110660975 0.245 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr14_+_32546274 0.243 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr4_-_52883786 0.242 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr1_+_164529004 0.241 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1



pre-B-cell leukemia homeobox 1



chr6_-_152639479 0.240 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_+_948803 0.240 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr14_+_32546145 0.240 ENST00000556611.1
ENST00000539826.2
ARHGAP5

Rho GTPase activating protein 5

chr11_+_65190245 0.235 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1


nuclear paraspeckle assembly transcript 1 (non-protein coding)


chr8_+_92261516 0.234 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr18_+_3451584 0.230 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr2_+_191208196 0.227 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1



inositol polyphosphate-1-phosphatase



chr6_-_47009996 0.225 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr21_-_28215332 0.223 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_-_95945246 0.222 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr8_+_98900132 0.221 ENST00000520016.1
MATN2
matrilin 2
chr11_-_110460409 0.220 ENST00000529591.1
ARHGAP20
Rho GTPase activating protein 20
chr12_-_47219733 0.214 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4


solute carrier family 38, member 4


chr1_+_164528437 0.208 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr2_+_191208601 0.202 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1


inositol polyphosphate-1-phosphatase


chr3_+_171844762 0.202 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr17_-_29624343 0.202 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr8_-_72274095 0.198 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_8075693 0.197 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr1_+_164600184 0.194 ENST00000482110.1
PBX1
pre-B-cell leukemia homeobox 1
chr3_+_69812877 0.191 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr12_+_41086297 0.190 ENST00000551295.2
CNTN1
contactin 1
chr3_+_184055240 0.188 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr12_+_51318513 0.188 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr4_-_84256024 0.187 ENST00000311412.5
HPSE
heparanase
chr2_+_191208656 0.186 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr8_-_120685608 0.185 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_-_13835147 0.180 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr11_-_61735029 0.179 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1
chr7_-_92777606 0.178 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr12_-_47226152 0.177 ENST00000546940.1
SLC38A4
solute carrier family 38, member 4
chr17_-_39123144 0.173 ENST00000355612.2
KRT39
keratin 39
chr8_-_27468717 0.172 ENST00000520796.1
ENST00000520491.1
CLU

clusterin

chr2_+_191208791 0.170 ENST00000423767.1
ENST00000451089.1
INPP1

inositol polyphosphate-1-phosphatase

chr4_-_84255935 0.168 ENST00000513463.1
HPSE
heparanase
chr10_+_52833883 0.167 ENST00000373980.4
PRKG1
protein kinase, cGMP-dependent, type I
chr2_-_152830479 0.166 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr3_-_46068969 0.163 ENST00000542109.1
ENST00000395946.2
XCR1

chemokine (C motif) receptor 1

chr5_+_140593509 0.163 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr9_+_92219919 0.163 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr5_-_43412418 0.160 ENST00000537013.1
ENST00000361115.4
CCL28

chemokine (C-C motif) ligand 28

chr6_-_56716686 0.156 ENST00000520645.1
DST
dystonin
chr11_-_87908600 0.156 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38


RAB38, member RAS oncogene family


chr11_+_101918153 0.155 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr1_+_36789335 0.153 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chrX_+_10124977 0.152 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr12_-_100378006 0.152 ENST00000547776.2
ENST00000329257.7
ENST00000547010.1
ANKS1B


ankyrin repeat and sterile alpha motif domain containing 1B


chr17_+_6900201 0.151 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr1_-_153514241 0.149 ENST00000368718.1
ENST00000359215.1
S100A5

S100 calcium binding protein A5

chr15_-_52587945 0.149 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr12_-_11139511 0.148 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr18_+_3450161 0.148 ENST00000551402.1
ENST00000577543.1
TGIF1

TGFB-induced factor homeobox 1

chr2_+_98703643 0.145 ENST00000477737.1
VWA3B
von Willebrand factor A domain containing 3B
chr1_+_79115503 0.143 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr1_+_78470530 0.143 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_93747425 0.142 ENST00000315099.2
STX19
syntaxin 19
chr8_-_18541603 0.142 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr7_-_92747269 0.141 ENST00000446617.1
ENST00000379958.2
SAMD9

sterile alpha motif domain containing 9

chr11_+_66824276 0.140 ENST00000308831.2
RHOD
ras homolog family member D
chr12_-_11287243 0.138 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr17_-_5026397 0.137 ENST00000250076.3
ZNF232
zinc finger protein 232
chr1_-_155881156 0.134 ENST00000539040.1
ENST00000368323.3
RIT1

Ras-like without CAAX 1

chr7_+_116596704 0.134 ENST00000597499.1
ST7-OT4
ST7 overlapping transcript 4
chr5_-_124081008 0.134 ENST00000306315.5
ZNF608
zinc finger protein 608
chr4_+_74301880 0.133 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr3_-_145940126 0.133 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr11_+_66824303 0.133 ENST00000533360.1
RHOD
ras homolog family member D
chr20_-_61274656 0.132 ENST00000370520.3
RP11-93B14.6
HCG2018282; Uncharacterized protein
chr1_-_221915418 0.131 ENST00000323825.3
ENST00000366899.3
DUSP10

dual specificity phosphatase 10

chr12_-_7244469 0.131 ENST00000538050.1
ENST00000536053.2
C1R

complement component 1, r subcomponent

chr9_-_93925369 0.128 ENST00000457976.1
RP11-305L7.3
RP11-305L7.3
chr4_-_11431389 0.128 ENST00000002596.5
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chrX_-_48827976 0.127 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr14_-_77889860 0.126 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr6_-_53530474 0.121 ENST00000370905.3
KLHL31
kelch-like family member 31
chr8_-_95274536 0.120 ENST00000297596.2
ENST00000396194.2
GEM

GTP binding protein overexpressed in skeletal muscle

chr3_+_77088989 0.120 ENST00000461745.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chrX_+_49028265 0.119 ENST00000376322.3
ENST00000376327.5
PLP2

proteolipid protein 2 (colonic epithelium-enriched)

chr11_+_128563652 0.117 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_-_179343226 0.116 ENST00000434643.2
FKBP7
FK506 binding protein 7
chr7_-_142169013 0.115 ENST00000454561.2
TRBV5-4
T cell receptor beta variable 5-4
chr6_+_152130240 0.115 ENST00000427531.2
ESR1
estrogen receptor 1
chr4_-_114900831 0.113 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr2_-_211168332 0.113 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr2_+_201994042 0.111 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_164528616 0.109 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr14_+_85996471 0.108 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr20_-_30310693 0.106 ENST00000307677.4
ENST00000420653.1
BCL2L1

BCL2-like 1

chr2_-_179343268 0.105 ENST00000424785.2
FKBP7
FK506 binding protein 7
chr5_+_145317356 0.105 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr16_-_85969774 0.104 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr1_-_155880672 0.103 ENST00000609492.1
ENST00000368322.3
RIT1

Ras-like without CAAX 1

chr4_+_41540160 0.102 ENST00000503057.1
ENST00000511496.1
LIMCH1

LIM and calponin homology domains 1

chr8_-_15095832 0.102 ENST00000382080.1
SGCZ
sarcoglycan, zeta
chr2_-_55277692 0.101 ENST00000394611.2
RTN4
reticulon 4
chr2_-_55277654 0.101 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr7_-_64023410 0.099 ENST00000447137.2
ZNF680
zinc finger protein 680
chr10_-_116444371 0.099 ENST00000533213.2
ENST00000369252.4
ABLIM1

actin binding LIM protein 1

chr14_+_85996507 0.098 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr17_+_38024417 0.098 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
ZPBP2



zona pellucida binding protein 2



chrX_+_100224676 0.098 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr2_+_204192942 0.096 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr2_+_149974684 0.095 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chrX_+_22056165 0.095 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr12_+_32654965 0.094 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chrX_+_86772787 0.094 ENST00000373114.4
KLHL4
kelch-like family member 4
chr3_+_178866199 0.093 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr13_+_114462193 0.093 ENST00000375353.3
TMEM255B
transmembrane protein 255B
chr4_+_26322185 0.092 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr3_-_98241760 0.091 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1










claudin domain containing 1










chr15_+_43885252 0.090 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B



creatine kinase, mitochondrial 1B



chr1_+_182584314 0.090 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr12_-_39734783 0.089 ENST00000552961.1
KIF21A
kinesin family member 21A
chr3_-_98241598 0.089 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1



claudin domain containing 1



chr12_+_93130311 0.089 ENST00000344636.3
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr2_+_190541153 0.088 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR



ankyrin and armadillo repeat containing



chr12_+_13349711 0.087 ENST00000538364.1
ENST00000396301.3
EMP1

epithelial membrane protein 1

chr1_-_11118896 0.086 ENST00000465788.1
SRM
spermidine synthase
chr11_+_85566422 0.086 ENST00000342404.3
CCDC83
coiled-coil domain containing 83
chrX_-_73051037 0.085 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr6_-_24489842 0.085 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr3_-_27763803 0.084 ENST00000449599.1
EOMES
eomesodermin
chr5_+_159343688 0.084 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr1_-_31666767 0.084 ENST00000530145.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr4_+_80584903 0.084 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr12_+_13349650 0.083 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr7_-_78400598 0.083 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_+_10292308 0.083 ENST00000377081.1
KIF1B
kinesin family member 1B
chr17_+_36584662 0.083 ENST00000431231.2
ENST00000437668.3
ARHGAP23

Rho GTPase activating protein 23

chr11_+_123986069 0.082 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A





von Willebrand factor A domain containing 5A





chr1_+_111889212 0.082 ENST00000369737.4
PIFO
primary cilia formation
chr4_+_39046615 0.082 ENST00000261425.3
ENST00000508137.2
KLHL5

kelch-like family member 5

chr4_+_26322409 0.081 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chrX_+_86772707 0.080 ENST00000373119.4
KLHL4
kelch-like family member 4
chr6_-_39902185 0.080 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
MOCS1


molybdenum cofactor synthesis 1


chr10_-_33623310 0.079 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1



neuropilin 1



chr3_+_98451093 0.079 ENST00000483910.1
ENST00000460774.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr6_-_39902160 0.078 ENST00000340692.5
MOCS1
molybdenum cofactor synthesis 1
chr10_-_33623564 0.078 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr12_-_123560608 0.077 ENST00000541244.1
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr2_+_128458514 0.077 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr12_+_48225126 0.077 ENST00000550909.1
ENST00000550720.1
ENST00000548564.1
RP5-1057I20.2


RP5-1057I20.2


chr11_-_124806297 0.076 ENST00000298251.4
HEPACAM
hepatic and glial cell adhesion molecule
chr18_+_3247413 0.076 ENST00000579226.1
ENST00000217652.3
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr3_+_98451532 0.075 ENST00000486334.2
ENST00000394162.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr7_-_150777920 0.075 ENST00000353841.2
ENST00000297532.6
FASTK

Fas-activated serine/threonine kinase

chr5_+_102090974 0.074 ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_-_149535190 0.074 ENST00000517488.1
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_-_133055896 0.072 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3





vanin 3





chr7_-_150777949 0.072 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr2_-_238322800 0.072 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr5_-_108063949 0.071 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr4_-_48683188 0.070 ENST00000505759.1
FRYL
FRY-like
chr3_-_108476231 0.069 ENST00000295755.6
RETNLB
resistin like beta
chr17_+_48610074 0.069 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3



epsin 3



chr12_+_41086215 0.068 ENST00000547702.1
ENST00000551424.1
CNTN1

contactin 1

chr2_-_122247879 0.068 ENST00000545861.1
CLASP1
cytoplasmic linker associated protein 1
chr4_+_166794383 0.067 ENST00000061240.2
ENST00000507499.1
TLL1

tolloid-like 1

chr12_-_90049878 0.067 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr8_-_28747424 0.067 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
INTS9




integrator complex subunit 9




chr13_-_99910673 0.067 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chr2_+_166326157 0.067 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3


cysteine-serine-rich nuclear protein 3


chr2_+_204193149 0.067 ENST00000422511.2
ABI2
abl-interactor 2
chr5_+_131409476 0.066 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr2_-_128643496 0.066 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr8_-_28747717 0.066 ENST00000416984.2
INTS9
integrator complex subunit 9
chr2_-_55276320 0.065 ENST00000357376.3
RTN4
reticulon 4
chr19_-_39390212 0.065 ENST00000437828.1
SIRT2
sirtuin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.7 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.2 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.3 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) sensory neuron axon guidance(GO:0097374) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 1.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.0 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.0 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.0 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.0 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.3 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.0 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555) progesterone secretion(GO:0042701)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:2001113 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.0 0.0 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.4 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1 0.4 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.3 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN