Motif ID: MLX_USF2_USF1_PAX2

Z-value: 0.617


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
USF1hg19_v2_chr1_-_161015752_161015778-0.751.9e-02Click!
MLXhg19_v2_chr17_+_40719073_407190920.713.3e-02Click!
USF2hg19_v2_chr19_+_35759824_357598910.703.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MLX_USF2_USF1_PAX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_58145889 1.849 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr8_+_120220561 1.409 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr8_+_75896731 1.206 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr1_-_11865982 1.077 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr8_+_75896849 1.000 ENST00000520277.1
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr1_+_150254936 0.935 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr1_-_11866034 0.895 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_+_105937068 0.798 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chrX_-_102319092 0.734 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr14_-_54420133 0.702 ENST00000559501.1
ENST00000558984.1
BMP4

bone morphogenetic protein 4

chr4_+_37455536 0.694 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19

chr6_-_33385823 0.647 ENST00000494751.1
ENST00000374496.3
CUTA

cutA divalent cation tolerance homolog (E. coli)

chrX_+_105936982 0.637 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr3_-_170626418 0.636 ENST00000474096.1
ENST00000295822.2
EIF5A2

eukaryotic translation initiation factor 5A2

chr9_-_90589586 0.627 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr9_-_90589402 0.623 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chrX_-_102565932 0.599 ENST00000372674.1
ENST00000372677.3
BEX2

brain expressed X-linked 2

chr6_-_33385655 0.592 ENST00000440279.3
ENST00000607266.1
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr6_-_33385854 0.581 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr3_-_170626376 0.578 ENST00000487522.1
ENST00000474417.1
EIF5A2

eukaryotic translation initiation factor 5A2

chrX_-_102565858 0.568 ENST00000449185.1
ENST00000536889.1
BEX2

brain expressed X-linked 2

chr6_-_33385902 0.543 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_+_121322832 0.533 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr6_-_33385870 0.530 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chrX_-_100662881 0.516 ENST00000218516.3
GLA
galactosidase, alpha
chr2_+_85981008 0.512 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr16_-_68269971 0.470 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr1_+_11866207 0.469 ENST00000312413.6
ENST00000346436.6
CLCN6

chloride channel, voltage-sensitive 6

chr5_-_1112141 0.435 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr1_+_15853308 0.425 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DNAJC16


DnaJ (Hsp40) homolog, subfamily C, member 16


chr6_+_125524785 0.424 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr9_-_114557207 0.419 ENST00000374287.3
ENST00000374283.5
C9orf84

chromosome 9 open reading frame 84

chr2_+_113403434 0.416 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr10_+_52751010 0.406 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr2_-_172967621 0.396 ENST00000234198.4
ENST00000466293.2
DLX2

distal-less homeobox 2

chr1_+_11866270 0.382 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6


chloride channel, voltage-sensitive 6


chr6_-_18122843 0.373 ENST00000340650.3
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
chr6_-_44225231 0.368 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2



solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2



chrX_+_10126488 0.362 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4


chloride channel, voltage-sensitive 4


chr1_-_111746966 0.356 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr3_+_184032313 0.339 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1








eukaryotic translation initiation factor 4 gamma, 1








chr3_+_184032419 0.333 ENST00000352767.3
ENST00000427141.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr3_+_184032283 0.331 ENST00000346169.2
ENST00000414031.1
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr1_+_43613612 0.327 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr7_-_121944491 0.324 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr14_-_94443105 0.320 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr22_+_35776828 0.319 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr5_+_94890778 0.319 ENST00000380009.4
ARSK
arylsulfatase family, member K
chr4_+_76439095 0.317 ENST00000506261.1
THAP6
THAP domain containing 6
chr1_+_43613566 0.312 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr5_-_132299290 0.308 ENST00000378595.3
AFF4
AF4/FMR2 family, member 4
chr22_-_36903101 0.301 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr12_-_65153175 0.298 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
GNS


glucosamine (N-acetyl)-6-sulfatase


chr1_+_3816936 0.297 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
RP13-15E13.1


long intergenic non-protein coding RNA 1134


chr19_-_5340730 0.294 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr9_+_96928516 0.292 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr19_-_36545128 0.291 ENST00000538849.1
THAP8
THAP domain containing 8
chr1_+_10092890 0.290 ENST00000253251.8
ENST00000377157.3
UBE4B

ubiquitination factor E4B

chr1_+_10093188 0.290 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr3_-_169899504 0.286 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
PHC3









polyhomeotic homolog 3 (Drosophila)









chr2_-_136875712 0.282 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr22_-_36903069 0.277 ENST00000216187.6
ENST00000423980.1
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr12_-_63328817 0.277 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_-_64761078 0.270 ENST00000341099.4
ENST00000556275.1
ENST00000542956.1
ENST00000353772.3
ENST00000357782.2
ENST00000267525.6
ESR2





estrogen receptor 2 (ER beta)





chr5_+_150404904 0.266 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr6_+_31865552 0.266 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr4_+_76439649 0.264 ENST00000507557.1
THAP6
THAP domain containing 6
chr1_-_31712401 0.264 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr16_-_28503080 0.260 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3




ceroid-lipofuscinosis, neuronal 3




chr5_-_121413974 0.260 ENST00000231004.4
LOX
lysyl oxidase
chr9_-_123476719 0.258 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr16_-_28503357 0.257 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3







ceroid-lipofuscinosis, neuronal 3







chr9_-_123476612 0.255 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr1_-_204329013 0.254 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr5_-_176730733 0.254 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr5_+_150827143 0.247 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1


solute carrier family 36 (proton/amino acid symporter), member 1


chr2_+_27309605 0.243 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
KHK


ketohexokinase (fructokinase)


chr16_+_28986134 0.242 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr5_-_132299313 0.238 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr5_-_176730676 0.236 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24


RAB24, member RAS oncogene family


chr5_-_110074603 0.236 ENST00000515278.2
TMEM232
transmembrane protein 232
chr9_-_19127474 0.235 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
PLIN2



perilipin 2



chr5_+_149340282 0.234 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr1_-_53608249 0.232 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr12_-_53625958 0.230 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG



retinoic acid receptor, gamma



chr1_+_154193643 0.229 ENST00000456325.1
UBAP2L
ubiquitin associated protein 2-like
chr10_+_24738355 0.227 ENST00000307544.6
KIAA1217
KIAA1217
chr8_+_67039131 0.226 ENST00000315962.4
ENST00000353317.5
TRIM55

tripartite motif containing 55

chr8_+_71581565 0.226 ENST00000408926.3
ENST00000520030.1
XKR9

XK, Kell blood group complex subunit-related family, member 9

chr11_+_34645791 0.225 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
EHF


ets homologous factor


chr2_-_211036051 0.225 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chr2_+_33701286 0.225 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_-_28503327 0.224 ENST00000535392.1
ENST00000395653.4
CLN3

ceroid-lipofuscinosis, neuronal 3

chr2_+_33701707 0.219 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3


RAS guanyl releasing protein 3 (calcium and DAG-regulated)


chr2_+_220042933 0.217 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr1_+_183605222 0.216 ENST00000536277.1
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr11_-_17035943 0.216 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7



pleckstrin homology domain containing, family A member 7



chrX_+_77166172 0.214 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr22_-_36902522 0.211 ENST00000397223.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr2_+_176972000 0.210 ENST00000249504.5
HOXD11
homeobox D11
chr3_+_184530173 0.208 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_+_183605200 0.206 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr12_+_123849462 0.205 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr5_-_131132614 0.204 ENST00000307968.7
ENST00000307954.8
FNIP1

folliculin interacting protein 1

chr2_+_177053307 0.204 ENST00000331462.4
HOXD1
homeobox D1
chrX_-_13835461 0.203 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chrX_+_10124977 0.203 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr2_+_46926326 0.203 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr5_+_133706865 0.201 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr10_+_23728198 0.200 ENST00000376495.3
OTUD1
OTU domain containing 1
chr2_-_148778323 0.199 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr12_-_49318715 0.198 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr4_+_75310851 0.196 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr17_+_62223320 0.196 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr2_+_240323439 0.194 ENST00000428471.1
ENST00000413029.1
AC062017.1

Uncharacterized protein

chr10_-_104001231 0.193 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr8_+_103876528 0.192 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2

HCG15011, isoform CRA_a; Protein LOC100996457

chr4_-_83933999 0.191 ENST00000510557.1
LIN54
lin-54 homolog (C. elegans)
chr4_+_75311019 0.190 ENST00000502307.1
AREG
amphiregulin
chr14_-_81687575 0.189 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr14_-_81687197 0.189 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr5_-_131132658 0.188 ENST00000511848.1
ENST00000510461.1
ENST00000514667.1
FNIP1

CTC-432M15.3
folliculin interacting protein 1

Folliculin-interacting protein 1
chrX_-_13835147 0.188 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr17_-_35969409 0.187 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG







synergin, gamma







chr8_-_95274536 0.186 ENST00000297596.2
ENST00000396194.2
GEM

GTP binding protein overexpressed in skeletal muscle

chr4_-_40632605 0.185 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr4_-_99850243 0.184 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E



eukaryotic translation initiation factor 4E



chr1_-_155211065 0.183 ENST00000427500.3
GBA
glucosidase, beta, acid
chrX_-_43832711 0.183 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr9_-_131709858 0.182 ENST00000372586.3
DOLK
dolichol kinase
chr4_-_48116540 0.181 ENST00000506073.1
TXK
TXK tyrosine kinase
chr17_+_72428218 0.180 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr5_+_172483347 0.179 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF



CREB3 regulatory factor



chr1_-_35497283 0.179 ENST00000373333.1
ZMYM6
zinc finger, MYM-type 6
chr12_-_90102594 0.179 ENST00000428670.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr6_-_19804973 0.177 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2


RP4-625H18.2


chr5_+_149340339 0.177 ENST00000433184.1
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr8_-_71157595 0.174 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr4_-_83934078 0.174 ENST00000505397.1
LIN54
lin-54 homolog (C. elegans)
chr1_-_111743285 0.173 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr16_+_28986085 0.173 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1



spinster homolog 1 (Drosophila)



chr14_-_94443065 0.171 ENST00000555287.1
ASB2
ankyrin repeat and SOCS box containing 2
chr1_-_155211017 0.171 ENST00000536770.1
ENST00000368373.3
GBA

glucosidase, beta, acid

chr1_+_32712815 0.171 ENST00000373582.3
FAM167B
family with sequence similarity 167, member B
chr4_-_23891693 0.169 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr12_-_90103077 0.169 ENST00000551310.1
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_-_227664474 0.168 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr4_+_76439665 0.168 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6







THAP domain containing 6







chr5_-_133706695 0.164 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3





cyclin-dependent kinase-like 3





chr1_-_35497233 0.164 ENST00000415531.1
ZMYM6
zinc finger, MYM-type 6
chr4_-_819901 0.163 ENST00000304062.6
CPLX1
complexin 1
chr9_+_92219919 0.162 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr16_+_28985542 0.161 ENST00000567771.1
ENST00000568388.1
SPNS1

spinster homolog 1 (Drosophila)

chr5_+_173315283 0.159 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr19_+_40854559 0.159 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3








phospholipase D family, member 3








chrX_+_102883887 0.157 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chr1_+_154193325 0.156 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L





ubiquitin associated protein 2-like





chr8_-_95961578 0.156 ENST00000448464.2
ENST00000342697.4
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr2_-_198364581 0.155 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr11_+_67776012 0.155 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr19_+_40854363 0.155 ENST00000599685.1
ENST00000392032.2
PLD3

phospholipase D family, member 3

chr2_-_120980939 0.153 ENST00000426077.2
TMEM185B
transmembrane protein 185B
chr1_-_154193091 0.152 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43


chromosome 1 open reading frame 43


chr19_-_49016418 0.149 ENST00000270238.3
LMTK3
lemur tyrosine kinase 3
chr1_-_156265438 0.147 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr8_+_67039278 0.147 ENST00000276573.7
ENST00000350034.4
TRIM55

tripartite motif containing 55

chr15_+_32322709 0.147 ENST00000455693.2
CHRNA7
cholinergic receptor, nicotinic, alpha 7 (neuronal)
chr7_-_1595871 0.146 ENST00000319010.5
TMEM184A
transmembrane protein 184A
chr18_+_32398326 0.145 ENST00000269192.7
ENST00000591182.1
ENST00000597674.1
ENST00000556414.3
DTNA



dystrobrevin, alpha



chrX_+_100663243 0.144 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_-_220108309 0.144 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr16_+_31044812 0.144 ENST00000313843.3
STX4
syntaxin 4
chr16_+_10972818 0.144 ENST00000576601.1
CIITA
class II, major histocompatibility complex, transactivator
chr7_-_82073109 0.144 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_-_186649543 0.144 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_148778258 0.143 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr17_-_27503770 0.143 ENST00000533112.1
MYO18A
myosin XVIIIA
chr2_-_197036289 0.142 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr8_-_13134045 0.142 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr2_+_46926048 0.142 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chrX_+_105066524 0.141 ENST00000243300.9
ENST00000428173.2
NRK

Nik related kinase

chr2_-_238499337 0.140 ENST00000411462.1
ENST00000409822.1
RAB17

RAB17, member RAS oncogene family

chr1_-_183538319 0.140 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr12_-_66275350 0.140 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chr5_+_110074685 0.140 ENST00000355943.3
ENST00000447245.2
SLC25A46

solute carrier family 25, member 46

chr10_-_99447024 0.139 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr4_-_819880 0.138 ENST00000505203.1
CPLX1
complexin 1
chr1_-_154193009 0.138 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43


chromosome 1 open reading frame 43


chr2_-_136873735 0.138 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr2_+_233562015 0.137 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr21_-_43187231 0.137 ENST00000332512.3
ENST00000352483.2
RIPK4

receptor-interacting serine-threonine kinase 4

chr20_+_44519948 0.137 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr12_+_50355647 0.136 ENST00000293599.6
AQP5
aquaporin 5
chr10_+_12391685 0.135 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr20_+_44520009 0.135 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr5_+_149865377 0.135 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_+_184529948 0.134 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8


vacuolar protein sorting 8 homolog (S. cerevisiae)


chr6_-_19804877 0.133 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr8_-_18942240 0.132 ENST00000521475.1
PSD3
pleckstrin and Sec7 domain containing 3
chr3_+_184529929 0.131 ENST00000287546.4
ENST00000437079.3
VPS8

vacuolar protein sorting 8 homolog (S. cerevisiae)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 0.2 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.2 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 0.5 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 1.4 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.7 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.4 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 1.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 1.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 1.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0034395 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.2 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.4 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 2.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 1.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0098942 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746) cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:0021539 subthalamus development(GO:0021539)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.5 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0061582 colon epithelial cell migration(GO:0061580) intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.6 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 0.0 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.0 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.4 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) regulation of cellular response to X-ray(GO:2000683) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0016340 cellular magnesium ion homeostasis(GO:0010961) calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.0 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.1 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) negative regulation of axon extension involved in axon guidance(GO:0048843) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.7 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.0 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0032280 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 2.0 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 1.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 3.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.0 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 1.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.0 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.2 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins