Motif ID: MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.756


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_180199426-0.932.6e-04Click!
MEOX2hg19_v2_chr7_-_15726296_157264370.713.3e-02Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.324.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46716969 3.851 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_70653673 1.881 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr4_+_183065793 1.846 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr6_+_127898312 1.532 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr6_-_130182410 1.423 ENST00000368143.1
TMEM244
transmembrane protein 244
chr1_-_242612726 1.378 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr4_-_186570679 1.325 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr11_-_33913708 1.306 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr3_-_151034734 1.287 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr5_-_147286065 1.251 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr8_+_105235572 1.246 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr2_+_128293323 1.241 ENST00000389524.4
ENST00000428314.1
MYO7B

myosin VIIB

chrX_+_16668278 1.193 ENST00000380200.3
S100G
S100 calcium binding protein G
chr1_-_242612779 1.187 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr21_-_42219065 1.151 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr6_-_138866823 1.132 ENST00000342260.5
NHSL1
NHS-like 1
chr8_-_16424871 1.126 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr4_+_71384257 1.105 ENST00000339336.4
AMTN
amelotin
chr3_+_153599269 1.055 ENST00000463297.1
RP11-217E22.5
RP11-217E22.5
chr2_-_68052694 1.040 ENST00000457448.1
AC010987.6
AC010987.6
chr4_+_71384300 1.023 ENST00000504451.1
AMTN
amelotin
chr3_-_157221128 1.021 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr15_+_48483736 1.005 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr6_-_138833630 0.981 ENST00000533765.1
NHSL1
NHS-like 1
chr17_+_39261584 0.972 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr1_-_150738261 0.971 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr2_+_90248739 0.917 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr14_-_75083313 0.907 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2

CTD-2207P18.2

chr13_-_86373536 0.873 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr2_-_227050079 0.868 ENST00000423838.1
AC068138.1
AC068138.1
chr6_+_78400375 0.854 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr20_-_7921090 0.846 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr3_+_111718173 0.843 ENST00000494932.1
TAGLN3
transgelin 3
chr3_+_111717600 0.817 ENST00000273368.4
TAGLN3
transgelin 3
chr7_-_143929936 0.808 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr3_+_111718036 0.803 ENST00000455401.2
TAGLN3
transgelin 3
chr11_-_26593779 0.794 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr3_+_111717511 0.794 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr6_+_43968306 0.787 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr11_-_26593677 0.750 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr11_-_26593649 0.689 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr12_+_20963632 0.681 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr13_+_110958124 0.677 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr3_-_157217328 0.669 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr4_-_186696425 0.669 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr13_+_77522632 0.665 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr12_+_20963647 0.665 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chrX_-_114253536 0.648 ENST00000371936.1
IL13RA2
interleukin 13 receptor, alpha 2
chr7_-_111424462 0.637 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr7_-_111424506 0.630 ENST00000450156.1
ENST00000494651.2
DOCK4

dedicator of cytokinesis 4

chr5_+_174151536 0.598 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr3_-_157221380 0.593 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr19_+_56270380 0.593 ENST00000434937.2
RFPL4A
ret finger protein-like 4A
chr10_+_69865866 0.573 ENST00000354393.2
MYPN
myopalladin
chr7_-_84122033 0.571 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_186696515 0.566 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr12_+_52056548 0.555 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr4_-_186696561 0.554 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr3_-_165555200 0.549 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr15_+_75080883 0.541 ENST00000567571.1
CSK
c-src tyrosine kinase
chr6_-_127780510 0.541 ENST00000487331.2
ENST00000483725.3
KIAA0408

KIAA0408

chr1_-_48937821 0.537 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr2_-_99871570 0.525 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2


lysozyme G-like 2


chr5_+_166711804 0.523 ENST00000518659.1
ENST00000545108.1
TENM2

teneurin transmembrane protein 2

chr11_-_26744908 0.515 ENST00000533617.1
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr19_-_7698599 0.514 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr13_-_95131923 0.514 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr1_-_92952433 0.511 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr3_-_157221357 0.504 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr22_-_32651326 0.502 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr8_-_10512569 0.501 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr20_-_56647116 0.493 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1

RP13-379L11.1

chr1_+_210501589 0.486 ENST00000413764.2
ENST00000541565.1
HHAT

hedgehog acyltransferase

chr8_-_49833978 0.483 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr5_-_137475071 0.481 ENST00000265191.2
NME5
NME/NM23 family member 5
chr1_-_48937838 0.479 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr13_-_88323514 0.477 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr4_-_89205350 0.474 ENST00000509340.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr6_-_139613269 0.469 ENST00000358430.3
TXLNB
taxilin beta
chr3_-_108248169 0.468 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr20_+_15177480 0.466 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr7_+_18329712 0.461 ENST00000433709.2
HDAC9
histone deacetylase 9
chr1_+_107682629 0.458 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1






netrin G1






chr6_+_76330355 0.458 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr11_-_5323226 0.451 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr13_+_31309645 0.451 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr15_+_63188009 0.441 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr2_-_61697862 0.439 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr19_+_56280507 0.434 ENST00000341750.4
RFPL4AL1
ret finger protein-like 4A-like 1
chr21_+_17792672 0.433 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chrX_-_92928557 0.420 ENST00000373079.3
ENST00000475430.2
NAP1L3

nucleosome assembly protein 1-like 3

chr10_+_94451574 0.419 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr12_+_26348246 0.404 ENST00000422622.2
SSPN
sarcospan
chr5_-_10761206 0.401 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr13_-_41593425 0.398 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr9_+_82188077 0.398 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_86650045 0.386 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_+_82767487 0.386 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr12_-_22063787 0.384 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_-_208031943 0.379 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr4_-_186733363 0.378 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr5_+_82767583 0.371 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr4_-_153601136 0.370 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr15_+_54305101 0.363 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C


unc-13 homolog C (C. elegans)


chr1_-_48866517 0.357 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chrX_-_124097620 0.353 ENST00000371130.3
ENST00000422452.2
TENM1

teneurin transmembrane protein 1

chr17_-_39211463 0.348 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr2_-_74618907 0.345 ENST00000421392.1
ENST00000437375.1
DCTN1

dynactin 1

chr6_+_130339710 0.345 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr6_-_116866773 0.344 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr2_-_203735484 0.338 ENST00000420558.1
ENST00000418208.1
ICA1L

islet cell autoantigen 1,69kDa-like

chr10_-_61900762 0.336 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_18690210 0.335 ENST00000379984.3
RS1
retinoschisin 1
chr3_+_156799587 0.333 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr18_+_6774000 0.331 ENST00000532723.1
ARHGAP28
Rho GTPase activating protein 28
chr8_-_49834299 0.331 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr3_+_159557637 0.330 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr10_-_14372870 0.328 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr12_+_78359999 0.321 ENST00000550503.1
NAV3
neuron navigator 3
chr14_-_38064198 0.309 ENST00000250448.2
FOXA1
forkhead box A1
chr17_-_73937116 0.307 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1


Fas (TNFRSF6) binding factor 1


chr2_-_74619152 0.306 ENST00000440727.1
ENST00000409240.1
DCTN1

dynactin 1

chr9_-_75488984 0.305 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1


RP11-151D14.1


chr11_-_5364809 0.302 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr3_+_119501557 0.301 ENST00000337940.4
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr12_+_57157100 0.301 ENST00000322165.1
HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6
chr3_+_111393501 0.300 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_109265033 0.299 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr2_+_3800169 0.299 ENST00000399143.3
DCDC2C
doublecortin domain containing 2C
chr7_-_99277610 0.298 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr13_-_31191642 0.296 ENST00000405805.1
HMGB1
high mobility group box 1
chr12_-_6233828 0.295 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr2_-_74618964 0.292 ENST00000417090.1
ENST00000409868.1
DCTN1

dynactin 1

chr1_+_153747746 0.291 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr17_-_38821373 0.289 ENST00000394052.3
KRT222
keratin 222
chr11_+_124481361 0.289 ENST00000284288.2
PANX3
pannexin 3
chr2_-_56274461 0.286 ENST00000446139.1
AC011306.2
AC011306.2
chr14_+_101359265 0.286 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr5_-_36301984 0.285 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L


RAN binding protein 3-like


chr3_+_158787098 0.283 ENST00000397832.2
ENST00000451172.1
ENST00000482126.1
IQCJ


IQ motif containing J


chr12_+_107712173 0.279 ENST00000280758.5
ENST00000420571.2
BTBD11

BTB (POZ) domain containing 11

chr20_+_44258165 0.279 ENST00000372643.3
WFDC10A
WAP four-disulfide core domain 10A
chr5_+_66300464 0.277 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr7_-_137039191 0.270 ENST00000438969.2
AC078842.3
AC078842.3
chr9_+_44867571 0.270 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr4_+_120056939 0.270 ENST00000307128.5
MYOZ2
myozenin 2
chr6_+_111408698 0.270 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr17_-_73937028 0.268 ENST00000586631.2
FBF1
Fas (TNFRSF6) binding factor 1
chr12_+_54378849 0.268 ENST00000515593.1
HOXC10
homeobox C10
chr14_-_81425828 0.267 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128


centrosomal protein 128kDa


chr2_+_204571375 0.266 ENST00000374478.4
CD28
CD28 molecule
chr12_+_19358228 0.262 ENST00000424268.1
ENST00000543806.1
PLEKHA5

pleckstrin homology domain containing, family A member 5

chr6_+_72922505 0.261 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_117747327 0.260 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6


FXYD6-FXYD2
FXYD domain containing ion transport regulator 6


FXYD6-FXYD2 readthrough
chr18_-_53177984 0.260 ENST00000543082.1
TCF4
transcription factor 4
chr6_+_13272904 0.258 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr14_-_52436247 0.256 ENST00000597846.1
AL358333.1
HCG2013195; Uncharacterized protein
chr4_-_176812842 0.254 ENST00000507540.1
GPM6A
glycoprotein M6A
chr17_+_56833184 0.251 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr15_+_80351910 0.250 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6

chr6_-_161695074 0.248 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4


1-acylglycerol-3-phosphate O-acyltransferase 4


chr4_+_183370146 0.247 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr2_-_27498208 0.247 ENST00000424577.1
ENST00000426569.1
SLC30A3

solute carrier family 30 (zinc transporter), member 3

chr6_+_72926145 0.247 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr12_+_28410128 0.246 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr6_-_161695042 0.246 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4


1-acylglycerol-3-phosphate O-acyltransferase 4


chr7_-_84121858 0.245 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr13_-_88323218 0.245 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG


MIR4500 host gene (non-protein coding)


chr10_+_118187379 0.243 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr8_+_107460147 0.243 ENST00000442977.2
OXR1
oxidation resistance 1
chr12_+_122688090 0.243 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr1_+_111415757 0.242 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chrM_+_10053 0.242 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr12_+_26348429 0.240 ENST00000242729.2
SSPN
sarcospan
chr15_-_65407524 0.238 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr17_-_77924627 0.237 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chr1_+_153746683 0.234 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr3_+_35721106 0.234 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21



cAMP-regulated phosphoprotein, 21kDa



chr3_+_111630451 0.232 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_+_138340049 0.231 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr4_-_138453606 0.231 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr6_+_72922590 0.230 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_158787041 0.229 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr7_-_55620433 0.228 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr14_+_95027772 0.227 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4

SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr20_+_61299155 0.226 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr5_+_156696362 0.224 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chrX_-_142722897 0.224 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr11_+_7618413 0.222 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_-_121659052 0.222 ENST00000512105.1
CTD-2544H17.1
CTD-2544H17.1
chr11_-_72070206 0.222 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_-_95391315 0.221 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr5_-_24645078 0.219 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr7_-_28220354 0.218 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr13_+_103459704 0.218 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr18_+_71815743 0.217 ENST00000169551.6
ENST00000580087.1
TIMM21

translocase of inner mitochondrial membrane 21 homolog (yeast)

chr18_-_53253112 0.217 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr14_+_100485712 0.216 ENST00000544450.2
EVL
Enah/Vasp-like
chr3_+_193809263 0.215 ENST00000457815.1
RP11-135A1.3
RP11-135A1.3
chr17_-_39203519 0.211 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 0.9 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.9 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.2 0.9 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 0.6 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 1.2 GO:1904970 brush border assembly(GO:1904970)
0.2 0.6 GO:0090427 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 0.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 0.7 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 0.8 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 2.3 GO:0097475 motor neuron migration(GO:0097475)
0.2 4.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.1 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.7 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.6 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 4.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.4 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.5 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 2.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.6 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.1 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.2 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.1 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 1.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.0 0.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.0 GO:0019230 proprioception(GO:0019230)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.4 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0061458 reproductive system development(GO:0061458)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:1902523 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.0 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.0 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289) positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 1.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 1.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) negative regulation of cyclic nucleotide catabolic process(GO:0030806) regulation of cAMP catabolic process(GO:0030820) negative regulation of cAMP catabolic process(GO:0030821) regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1900169 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.0 GO:0006173 dADP biosynthetic process(GO:0006173)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.0 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 2.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.0 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.0 GO:1903288 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.0 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0002544 chronic inflammatory response(GO:0002544)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 4.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0044305 calyx of Held(GO:0044305)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.0 2.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0060171 stereocilium membrane(GO:0060171)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 3.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 1.2 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.4 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.5 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 1.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.8 GO:0010181 FMN binding(GO:0010181)
0.0 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 1.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 1.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0019960 C-X3-C chemokine receptor activity(GO:0016495) C-X3-C chemokine binding(GO:0019960)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 6.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 1.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 4.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 2.0 GO:0003774 motor activity(GO:0003774)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.5 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.9 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 2.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters