Motif ID: MBD2

Z-value: 0.671


Transcription factors associated with MBD2:

Gene SymbolEntrez IDGene Name
MBD2 ENSG00000134046.7 MBD2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51751132_517511580.835.4e-03Click!


Activity profile for motif MBD2.

activity profile for motif MBD2


Sorted Z-values histogram for motif MBD2

Sorted Z-values for motif MBD2



Network of associatons between targets according to the STRING database.



First level regulatory network of MBD2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_130617029 0.858 ENST00000373203.4
ENG
endoglin
chr9_-_130616915 0.842 ENST00000344849.3
ENG
endoglin
chr13_+_27131798 0.636 ENST00000361042.4
WASF3
WAS protein family, member 3
chr13_+_27131887 0.636 ENST00000335327.5
WASF3
WAS protein family, member 3
chr6_+_107811162 0.579 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr4_-_6202247 0.562 ENST00000409021.3
ENST00000409371.3
JAKMIP1

janus kinase and microtubule interacting protein 1

chr5_+_176237478 0.557 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr4_-_6202291 0.537 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chrX_+_12156582 0.534 ENST00000380682.1
FRMPD4
FERM and PDZ domain containing 4
chr11_-_75236867 0.492 ENST00000376282.3
ENST00000336898.3
GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

chr4_+_2061119 0.464 ENST00000423729.2
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr9_+_129376722 0.429 ENST00000526117.1
ENST00000373474.4
ENST00000355497.5
ENST00000425646.2
ENST00000561065.1
LMX1B




LIM homeobox transcription factor 1, beta




chr17_+_65374075 0.383 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_+_11650709 0.362 ENST00000586059.1
CNN1
calponin 1, basic, smooth muscle
chr2_+_74212073 0.355 ENST00000441217.1
AC073046.25
AC073046.25
chr13_+_98795664 0.354 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr14_+_21538429 0.352 ENST00000298694.4
ENST00000555038.1
ARHGEF40

Rho guanine nucleotide exchange factor (GEF) 40

chr12_-_58159361 0.336 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr17_+_43971643 0.332 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT





microtubule-associated protein tau





chr17_+_43972010 0.332 ENST00000334239.8
ENST00000446361.3
MAPT

microtubule-associated protein tau

chr14_+_21538517 0.329 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr6_+_90142884 0.328 ENST00000369408.5
ENST00000339746.4
ENST00000447838.2
ANKRD6


ankyrin repeat domain 6


chr8_+_37654693 0.322 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr18_+_72265084 0.320 ENST00000582337.1
ZNF407
zinc finger protein 407
chr18_-_53255766 0.318 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr17_+_65373531 0.314 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr12_+_19282643 0.314 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5





pleckstrin homology domain containing, family A member 5





chr3_+_49591881 0.312 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr10_+_129845670 0.312 ENST00000467366.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr18_+_77155942 0.297 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_-_71802760 0.297 ENST00000295612.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr18_-_72265035 0.288 ENST00000585279.1
ENST00000580048.1
LINC00909

long intergenic non-protein coding RNA 909

chr19_-_11308190 0.287 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr13_+_98795505 0.281 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr13_+_98795434 0.281 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr10_+_115803650 0.270 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr12_+_122064673 0.268 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr11_-_115375107 0.267 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr6_+_1389989 0.259 ENST00000259806.1
FOXF2
forkhead box F2
chr4_-_6474173 0.257 ENST00000382599.4
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr6_-_45983549 0.256 ENST00000544153.1
CLIC5
chloride intracellular channel 5
chr2_-_61697862 0.256 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr14_-_21566731 0.254 ENST00000360947.3
ZNF219
zinc finger protein 219
chr10_+_129845823 0.249 ENST00000306042.5
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_-_32229523 0.248 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
BAI2



brain-specific angiogenesis inhibitor 2



chr1_-_6545502 0.247 ENST00000535355.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_39195037 0.246 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr9_-_80263220 0.244 ENST00000341700.6
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chr5_+_14143728 0.238 ENST00000344204.4
ENST00000537187.1
TRIO

trio Rho guanine nucleotide exchange factor

chr18_-_72264805 0.237 ENST00000577806.1
LINC00909
long intergenic non-protein coding RNA 909
chr16_+_28303804 0.231 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr2_-_208031542 0.227 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_-_48471454 0.223 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr18_+_77155856 0.222 ENST00000253506.5
ENST00000591814.1
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr16_-_30905584 0.216 ENST00000380317.4
BCL7C
B-cell CLL/lymphoma 7C
chr17_-_31404 0.216 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr12_+_121078355 0.215 ENST00000316803.3
CABP1
calcium binding protein 1
chr14_+_21566980 0.214 ENST00000418511.2
ENST00000554329.2
TMEM253

transmembrane protein 253

chr19_+_39904168 0.213 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2


pleckstrin homology domain containing, family G (with RhoGef domain) member 2


chr18_-_72921303 0.210 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr6_-_99797522 0.208 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr17_+_74864476 0.206 ENST00000301618.4
ENST00000569840.2
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr3_-_133969437 0.204 ENST00000460933.1
ENST00000296084.4
RYK

receptor-like tyrosine kinase

chr22_-_20004330 0.203 ENST00000263207.3
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr1_-_32229934 0.201 ENST00000398542.1
BAI2
brain-specific angiogenesis inhibitor 2
chr20_-_56284816 0.199 ENST00000395819.3
ENST00000341744.3
PMEPA1

prostate transmembrane protein, androgen induced 1

chr15_+_90544532 0.197 ENST00000268154.4
ZNF710
zinc finger protein 710
chr21_+_45875354 0.195 ENST00000291592.4
LRRC3
leucine rich repeat containing 3
chr1_-_6546001 0.192 ENST00000400913.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr12_-_120554534 0.191 ENST00000538903.1
ENST00000534951.1
RAB35

RAB35, member RAS oncogene family

chr19_+_49622646 0.191 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr3_-_149688896 0.184 ENST00000239940.7
PFN2
profilin 2
chr11_-_72353494 0.181 ENST00000544570.1
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr3_+_33155444 0.181 ENST00000320954.6
CRTAP
cartilage associated protein
chr3_-_149688502 0.181 ENST00000481767.1
ENST00000475518.1
PFN2

profilin 2

chr17_-_41623075 0.181 ENST00000545089.1
ETV4
ets variant 4
chr22_-_20792089 0.180 ENST00000405555.3
ENST00000266214.5
SCARF2

scavenger receptor class F, member 2

chr11_-_72353451 0.180 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr3_+_33155525 0.179 ENST00000449224.1
CRTAP
cartilage associated protein
chr17_-_41623259 0.179 ENST00000538265.1
ENST00000591713.1
ETV4

ets variant 4

chr1_-_54872059 0.178 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr17_-_61920280 0.178 ENST00000448276.2
ENST00000577990.1
SMARCD2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

chr17_-_61919812 0.175 ENST00000225742.9
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr7_+_40174565 0.172 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10





succinylCoA:glutarate-CoA transferase





chr12_+_50478977 0.172 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr12_+_50479109 0.171 ENST00000550477.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr12_-_57400227 0.171 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr20_+_55204351 0.170 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr1_+_11539204 0.169 ENST00000294484.6
ENST00000389575.3
PTCHD2

patched domain containing 2

chr12_-_93835665 0.168 ENST00000552442.1
ENST00000550657.1
UBE2N

ubiquitin-conjugating enzyme E2N

chr9_-_136933134 0.165 ENST00000303407.7
BRD3
bromodomain containing 3
chr12_+_122516626 0.165 ENST00000319080.7
MLXIP
MLX interacting protein
chr12_-_120554622 0.164 ENST00000229340.5
RAB35
RAB35, member RAS oncogene family
chr5_+_76506706 0.160 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B




phosphodiesterase 8B




chr22_+_19702069 0.159 ENST00000412544.1
SEPT5
septin 5
chr17_+_17942594 0.159 ENST00000268719.4
GID4
GID complex subunit 4
chr12_-_122017542 0.158 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr9_-_136933615 0.158 ENST00000371834.2
BRD3
bromodomain containing 3
chr17_+_17685422 0.157 ENST00000395774.1
RAI1
retinoic acid induced 1
chr4_-_140098339 0.157 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr12_+_50479101 0.156 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr13_-_46626820 0.153 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr17_-_41623009 0.149 ENST00000393664.2
ETV4
ets variant 4
chr9_-_136933092 0.149 ENST00000357885.2
BRD3
bromodomain containing 3
chr13_-_21476900 0.147 ENST00000400602.2
ENST00000255305.6
XPO4

exportin 4

chr15_+_101142722 0.146 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7


ankyrin repeat and SOCS box containing 7


chr3_+_112930306 0.145 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr3_+_133292759 0.142 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr7_-_558876 0.141 ENST00000354513.5
ENST00000402802.3
PDGFA

platelet-derived growth factor alpha polypeptide

chr13_-_46626847 0.141 ENST00000242848.4
ENST00000282007.3
ZC3H13

zinc finger CCCH-type containing 13

chr2_-_46769694 0.141 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr1_-_155243235 0.141 ENST00000355560.4
ENST00000368361.4
CLK2

CDC-like kinase 2

chr22_-_19419205 0.140 ENST00000340170.4
ENST00000263208.5
HIRA

histone cell cycle regulator

chr20_-_31172598 0.139 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr12_+_6875519 0.138 ENST00000389462.4
ENST00000540874.1
ENST00000309083.6
PTMS


parathymosin


chr19_-_11373128 0.138 ENST00000294618.7
DOCK6
dedicator of cytokinesis 6
chr1_-_150552006 0.137 ENST00000307940.3
ENST00000369026.2
MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

chr3_+_133292574 0.137 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr15_-_82338460 0.136 ENST00000558133.1
ENST00000329713.4
MEX3B

mex-3 RNA binding family member B

chr3_-_113415441 0.135 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr22_+_38035459 0.135 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr12_+_68042495 0.134 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr3_-_48470838 0.134 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr19_-_46148820 0.131 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr15_+_72766651 0.130 ENST00000379887.4
ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
chr3_+_159481988 0.130 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr19_-_17356697 0.129 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr2_-_70529126 0.127 ENST00000438759.1
ENST00000430566.1
FAM136A

family with sequence similarity 136, member A

chr1_-_156698181 0.125 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr9_+_36136700 0.125 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLIPR2


GLI pathogenesis-related 2


chr3_+_133292851 0.125 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr2_-_25564750 0.124 ENST00000321117.5
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr15_+_80351977 0.123 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6



zinc finger, AN1-type domain 6



chr19_+_42388437 0.123 ENST00000378152.4
ENST00000337665.4
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr15_+_91073193 0.123 ENST00000560098.1
ENST00000268184.6
CRTC3

CREB regulated transcription coactivator 3

chr17_+_17942684 0.122 ENST00000376345.3
GID4
GID complex subunit 4
chr11_-_75141206 0.122 ENST00000376292.4
KLHL35
kelch-like family member 35
chr15_+_78832747 0.122 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4






proteasome (prosome, macropain) subunit, alpha type, 4






chr3_-_52001448 0.122 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chr22_+_38035623 0.121 ENST00000336738.5
ENST00000442465.2
SH3BP1

SH3-domain binding protein 1

chr16_+_3019246 0.121 ENST00000318782.8
ENST00000293978.8
PAQR4

progestin and adipoQ receptor family member IV

chr16_+_3019552 0.121 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr12_+_19282713 0.120 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
PLEKHA5


pleckstrin homology domain containing, family A member 5


chr2_+_220306238 0.120 ENST00000435853.1
SPEG
SPEG complex locus
chr12_-_48213568 0.120 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7




histone deacetylase 7




chr16_+_3019309 0.120 ENST00000576565.1
PAQR4
progestin and adipoQ receptor family member IV
chr15_-_56035177 0.120 ENST00000389286.4
ENST00000561292.1
PRTG

protogenin

chr11_+_46354455 0.118 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr19_+_10527449 0.118 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr11_-_79151695 0.118 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr14_-_99737822 0.117 ENST00000345514.2
ENST00000443726.2
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr12_+_3068957 0.115 ENST00000543035.1
TEAD4
TEA domain family member 4
chr11_-_67271723 0.115 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
PITPNM1


phosphatidylinositol transfer protein, membrane-associated 1


chr16_+_2022036 0.115 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr3_-_133969673 0.115 ENST00000427044.2
RYK
receptor-like tyrosine kinase
chr22_+_19701985 0.114 ENST00000455784.2
ENST00000406395.1
SEPT5

septin 5

chr2_-_208030886 0.112 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr9_+_35829208 0.111 ENST00000439587.2
ENST00000377991.4
TMEM8B

transmembrane protein 8B

chr7_-_8301768 0.111 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr12_-_124419531 0.110 ENST00000514254.2
DNAH10OS
dynein, axonemal, heavy chain 10 opposite strand
chr7_-_8301682 0.110 ENST00000396675.3
ENST00000430867.1
ICA1

islet cell autoantigen 1, 69kDa

chr3_+_50273625 0.109 ENST00000536647.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr15_-_90294523 0.109 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr15_+_40650408 0.107 ENST00000267889.3
DISP2
dispatched homolog 2 (Drosophila)
chr10_+_104180580 0.106 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr8_+_145137489 0.105 ENST00000355091.4
ENST00000525087.1
ENST00000361036.6
ENST00000524418.1
GPAA1



glycosylphosphatidylinositol anchor attachment 1



chr15_+_78833071 0.104 ENST00000559365.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr12_+_105724613 0.103 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr12_+_111051902 0.103 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1



tectonic family member 1



chr3_-_27525826 0.103 ENST00000454389.1
ENST00000440156.1
ENST00000437179.1
ENST00000446700.1
ENST00000455077.1
ENST00000435667.2
ENST00000388777.4
ENST00000425128.2
SLC4A7







solute carrier family 4, sodium bicarbonate cotransporter, member 7







chr9_-_135996537 0.102 ENST00000372050.3
ENST00000372047.3
RALGDS

ral guanine nucleotide dissociation stimulator

chr22_-_42739533 0.102 ENST00000515426.1
TCF20
transcription factor 20 (AR1)
chr7_-_127032114 0.100 ENST00000436992.1
ZNF800
zinc finger protein 800
chr21_-_27542972 0.100 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP






amyloid beta (A4) precursor protein






chr17_-_5372229 0.100 ENST00000433302.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr3_-_27525865 0.099 ENST00000445684.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_+_21467642 0.099 ENST00000222584.3
ENST00000432066.2
SP4

Sp4 transcription factor

chr3_+_120461484 0.097 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1



general transcription factor IIE, polypeptide 1, alpha 56kDa



chr12_-_57824739 0.097 ENST00000347140.3
ENST00000402412.1
R3HDM2

R3H domain containing 2

chr10_+_128593978 0.096 ENST00000280333.6
DOCK1
dedicator of cytokinesis 1
chr19_-_41222775 0.096 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4


aarF domain containing kinase 4


chr7_-_21985656 0.095 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr1_+_84543734 0.095 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_112930946 0.095 ENST00000462425.1
BOC
BOC cell adhesion associated, oncogene regulated
chr1_+_43148625 0.093 ENST00000436427.1
YBX1
Y box binding protein 1
chr1_+_215740709 0.092 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3
chr9_+_140772226 0.091 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
CACNA1B





calcium channel, voltage-dependent, N type, alpha 1B subunit





chr3_-_53080047 0.091 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr15_+_78833105 0.089 ENST00000558341.1
ENST00000559437.1
PSMA4

proteasome (prosome, macropain) subunit, alpha type, 4

chr17_-_7142725 0.089 ENST00000571362.1
ENST00000576955.1
ENST00000320316.3
PHF23


PHD finger protein 23


chr6_+_1610681 0.089 ENST00000380874.2
FOXC1
forkhead box C1
chr17_-_7141490 0.089 ENST00000574236.1
ENST00000572789.1
PHF23

PHD finger protein 23

chr19_+_55795493 0.088 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr20_-_62710832 0.088 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr7_-_19157248 0.086 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr1_-_160040038 0.086 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chrX_+_152953505 0.086 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chr11_-_47198380 0.086 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2








ADP-ribosylation factor GTPase activating protein 2








chr1_-_156698591 0.085 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr16_-_30905263 0.084 ENST00000572628.1
BCL7C
B-cell CLL/lymphoma 7C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.4 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.7 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.5 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 1.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.0 0.1 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.5 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.0 GO:0051153 regulation of myotube differentiation(GO:0010830) regulation of striated muscle cell differentiation(GO:0051153)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 0.1 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:1903317 regulation of protein processing(GO:0070613) regulation of protein maturation(GO:1903317)
0.0 0.0 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.7 GO:0045298 tubulin complex(GO:0045298)
0.1 0.2 GO:1990742 microvesicle(GO:1990742)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.4 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005534 galactose binding(GO:0005534)
0.2 0.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.6 PID_S1P_S1P3_PATHWAY S1P3 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation