Motif ID: MAFB

Z-value: 0.646


Transcription factors associated with MAFB:

Gene SymbolEntrez IDGene Name
MAFB ENSG00000204103.2 MAFB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFBhg19_v2_chr20_-_39317868_393178840.019.7e-01Click!


Activity profile for motif MAFB.

activity profile for motif MAFB


Sorted Z-values histogram for motif MAFB

Sorted Z-values for motif MAFB



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_120254510 0.965 ENST00000369409.4
PHGDH
phosphoglycerate dehydrogenase
chrX_-_74145273 0.779 ENST00000055682.6
KIAA2022
KIAA2022
chr2_+_30454390 0.641 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr4_+_15005391 0.636 ENST00000507071.1
ENST00000345451.3
ENST00000259997.5
ENST00000382395.3
ENST00000382401.3
CPEB2




cytoplasmic polyadenylation element binding protein 2




chr16_+_89642120 0.584 ENST00000268720.5
ENST00000319518.8
CPNE7

copine VII

chr4_-_168155577 0.583 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr4_-_168155700 0.581 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr17_-_19651668 0.550 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr4_-_168155169 0.547 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr7_+_155250824 0.546 ENST00000297375.4
EN2
engrailed homeobox 2
chr4_-_168155730 0.536 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr3_+_42977846 0.531 ENST00000383748.4
KRBOX1
KRAB box domain containing 1
chrX_+_105937068 0.519 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr11_+_134225909 0.495 ENST00000533324.1
GLB1L2
galactosidase, beta 1-like 2
chr18_+_52385068 0.492 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr16_-_4987065 0.488 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chr4_+_75858318 0.480 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr4_-_168155300 0.457 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr2_-_166650700 0.449 ENST00000422973.1
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr3_-_169487617 0.447 ENST00000330368.2
ACTRT3
actin-related protein T3
chr4_+_42399856 0.447 ENST00000319234.4
SHISA3
shisa family member 3
chrX_+_105936982 0.447 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr14_+_52780998 0.446 ENST00000557436.1
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr4_-_168155417 0.440 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr17_-_19651654 0.436 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr15_+_92397051 0.436 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr19_+_50979753 0.430 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
EMC10



ER membrane protein complex subunit 10



chr7_-_156433195 0.425 ENST00000333319.6
C7orf13
chromosome 7 open reading frame 13
chr7_+_95401851 0.416 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr7_-_124405681 0.413 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr5_+_140602904 0.408 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr14_+_52781079 0.393 ENST00000245457.5
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr3_-_185542761 0.389 ENST00000457616.2
ENST00000346192.3
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chrX_+_153656978 0.388 ENST00000369762.2
ENST00000422890.1
ATP6AP1

ATPase, H+ transporting, lysosomal accessory protein 1

chr1_+_60280458 0.379 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr4_+_75858290 0.376 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr17_+_72428218 0.375 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_-_27718052 0.375 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr14_-_54418598 0.374 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr2_-_166651152 0.362 ENST00000431484.1
ENST00000412248.1
GALNT3

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)

chr14_-_54317532 0.360 ENST00000418927.1
AL162759.1
AL162759.1
chr10_+_12391481 0.356 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr18_+_61554932 0.352 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr10_+_91087651 0.350 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_+_12391685 0.350 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr2_-_135476552 0.339 ENST00000281924.6
TMEM163
transmembrane protein 163
chr7_+_94536898 0.336 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr1_-_228135599 0.336 ENST00000272164.5
WNT9A
wingless-type MMTV integration site family, member 9A
chr17_-_72968837 0.335 ENST00000581676.1
HID1
HID1 domain containing
chr1_+_31883048 0.333 ENST00000536859.1
SERINC2
serine incorporator 2
chr8_-_110656995 0.330 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr17_+_72428266 0.329 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_-_19651598 0.326 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr3_-_185542817 0.322 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr12_-_52779433 0.322 ENST00000257951.3
KRT84
keratin 84
chr2_+_33701286 0.321 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_-_93204033 0.320 ENST00000359558.2
ENST00000360249.4
ENST00000426151.1
CALCR


calcitonin receptor


chr1_-_177134024 0.318 ENST00000367654.3
ASTN1
astrotactin 1
chr1_-_177133998 0.318 ENST00000367657.3
ASTN1
astrotactin 1
chr22_-_36013368 0.317 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr2_-_157189180 0.306 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr2_-_55277512 0.305 ENST00000402434.2
RTN4
reticulon 4
chr1_-_151826173 0.304 ENST00000368817.5
THEM5
thioesterase superfamily member 5
chr2_-_219925189 0.303 ENST00000295731.6
IHH
indian hedgehog
chr14_+_32546485 0.301 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5


Rho GTPase activating protein 5


chr1_-_44497024 0.299 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr3_-_169482840 0.299 ENST00000602385.1
TERC
telomerase RNA component
chrX_-_47479246 0.298 ENST00000295987.7
ENST00000340666.4
SYN1

synapsin I

chrX_-_43832711 0.294 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr11_-_94964354 0.293 ENST00000536441.1
SESN3
sestrin 3
chr5_+_129240151 0.292 ENST00000305031.4
CHSY3
chondroitin sulfate synthase 3
chr2_-_55277436 0.290 ENST00000354474.6
RTN4
reticulon 4
chr11_-_45928830 0.290 ENST00000449465.1
C11orf94
chromosome 11 open reading frame 94
chrX_+_153672468 0.287 ENST00000393600.3
FAM50A
family with sequence similarity 50, member A
chrX_-_48693955 0.284 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_+_32546145 0.282 ENST00000556611.1
ENST00000539826.2
ARHGAP5

Rho GTPase activating protein 5

chr2_+_191745560 0.281 ENST00000338435.4
GLS
glutaminase
chr6_+_32407619 0.277 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr7_-_130418888 0.276 ENST00000310992.4
KLF14
Kruppel-like factor 14
chr16_-_65155833 0.275 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11


cadherin 11, type 2, OB-cadherin (osteoblast)


chr8_-_110660975 0.274 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr17_-_72968809 0.274 ENST00000530857.1
ENST00000425042.2
HID1

HID1 domain containing

chr5_-_1112141 0.271 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr9_+_113431029 0.269 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK


muscle, skeletal, receptor tyrosine kinase


chr7_-_82073031 0.264 ENST00000356253.5
ENST00000423588.1
CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1

chr16_+_226658 0.264 ENST00000320868.5
ENST00000397797.1
HBA1

hemoglobin, alpha 1

chrX_+_153657009 0.264 ENST00000449556.1
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr7_+_7222233 0.263 ENST00000436587.2
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr7_-_82073109 0.262 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_+_15004165 0.261 ENST00000538197.1
ENST00000541112.1
ENST00000442003.2
CPEB2


cytoplasmic polyadenylation element binding protein 2


chr14_+_32546274 0.260 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr12_+_53491220 0.259 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr9_+_113431059 0.258 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr8_+_32405785 0.257 ENST00000287842.3
NRG1
neuregulin 1
chr2_+_191745535 0.257 ENST00000320717.3
GLS
glutaminase
chr8_+_106330920 0.252 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr22_-_38484922 0.249 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr8_+_32405728 0.249 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1




neuregulin 1




chr20_-_10654639 0.249 ENST00000254958.5
JAG1
jagged 1
chr8_+_31497271 0.249 ENST00000520407.1
NRG1
neuregulin 1
chr7_+_7222157 0.246 ENST00000419721.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr2_+_113403434 0.246 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr19_-_49015050 0.245 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr12_-_86230315 0.244 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chrX_-_153775426 0.243 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr7_+_139528952 0.243 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1



thromboxane A synthase 1 (platelet)



chr4_-_24914576 0.241 ENST00000502801.1
ENST00000428116.2
CCDC149

coiled-coil domain containing 149

chr14_+_75761099 0.241 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5

RP11-293M10.5

chr7_-_122526411 0.240 ENST00000449022.2
CADPS2
Ca++-dependent secretion activator 2
chr7_+_95401877 0.240 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1





dynein, cytoplasmic 1, intermediate chain 1





chr2_+_7005959 0.239 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr11_-_94964210 0.238 ENST00000416495.2
ENST00000393234.1
SESN3

sestrin 3

chr13_+_95364963 0.234 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr5_-_88180342 0.233 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr11_-_32452357 0.233 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr2_+_204192942 0.233 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr11_-_1776176 0.230 ENST00000429746.1
CTSD
cathepsin D
chr6_+_117586713 0.227 ENST00000352536.3
ENST00000326274.5
VGLL2

vestigial like 2 (Drosophila)

chr19_-_50979981 0.227 ENST00000595790.1
ENST00000600100.1
FAM71E1

family with sequence similarity 71, member E1

chr2_-_235405168 0.226 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr17_-_16472483 0.225 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287


zinc finger protein 287


chr2_+_207308539 0.225 ENST00000374416.1
ENST00000374415.3
ADAM23

ADAM metallopeptidase domain 23

chr2_-_166651191 0.224 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr9_-_86153218 0.224 ENST00000304195.3
ENST00000376438.1
FRMD3

FERM domain containing 3

chr8_-_41655107 0.223 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
ANK1





ankyrin 1, erythrocytic





chr6_+_160693591 0.223 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr19_-_5340730 0.221 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr8_-_26371608 0.221 ENST00000522362.2
PNMA2
paraneoplastic Ma antigen 2
chr4_+_78978724 0.220 ENST00000325942.6
ENST00000264895.6
ENST00000264899.6
FRAS1


Fraser syndrome 1


chr6_+_125474939 0.220 ENST00000527711.1
TPD52L1
tumor protein D52-like 1
chr1_+_224803995 0.219 ENST00000272133.3
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr7_+_139529040 0.219 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1


thromboxane A synthase 1 (platelet)


chr10_-_116164450 0.218 ENST00000369271.3
AFAP1L2
actin filament associated protein 1-like 2
chr7_-_73184588 0.218 ENST00000395145.2
CLDN3
claudin 3
chr4_+_126237554 0.218 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr2_-_55277654 0.217 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr6_-_94129244 0.217 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr18_-_35145593 0.216 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
CELF4


CUGBP, Elav-like family member 4


chr2_-_55277692 0.215 ENST00000394611.2
RTN4
reticulon 4
chr2_+_158114051 0.215 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr10_-_21463116 0.214 ENST00000417816.2
NEBL
nebulette
chr10_+_91061712 0.214 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr4_+_75310851 0.213 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr10_+_122216316 0.213 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
PPAPDC1A


phosphatidic acid phosphatase type 2 domain containing 1A


chr19_-_46526304 0.213 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr1_+_82266053 0.212 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr11_+_72929319 0.211 ENST00000393597.2
ENST00000311131.2
P2RY2

purinergic receptor P2Y, G-protein coupled, 2

chrX_-_13835461 0.211 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr9_-_113800981 0.210 ENST00000538760.1
LPAR1
lysophosphatidic acid receptor 1
chr5_-_67730240 0.209 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr5_+_99871004 0.209 ENST00000312637.4
FAM174A
family with sequence similarity 174, member A
chr1_-_24194771 0.209 ENST00000374479.3
FUCA1
fucosidase, alpha-L- 1, tissue
chr3_-_183543301 0.208 ENST00000318631.3
ENST00000431348.1
MAP6D1

MAP6 domain containing 1

chr4_-_110736505 0.208 ENST00000609440.1
RP11-602N24.3
RP11-602N24.3
chr9_+_127539425 0.208 ENST00000331715.9
OLFML2A
olfactomedin-like 2A
chr1_-_109203685 0.208 ENST00000402983.1
ENST00000420055.1
HENMT1

HEN1 methyltransferase homolog 1 (Arabidopsis)

chr10_-_116164239 0.207 ENST00000419268.1
ENST00000304129.4
ENST00000545353.1
AFAP1L2


actin filament associated protein 1-like 2


chr22_+_36649170 0.206 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1





apolipoprotein L, 1





chr4_+_75311019 0.206 ENST00000502307.1
AREG
amphiregulin
chrX_-_153775760 0.204 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD


glucose-6-phosphate dehydrogenase


chr17_-_28257080 0.204 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2




slingshot protein phosphatase 2




chr6_+_125540951 0.204 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr20_+_13202418 0.203 ENST00000262487.4
ISM1
isthmin 1, angiogenesis inhibitor
chr16_-_65156235 0.201 ENST00000564317.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_-_228028829 0.201 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr19_-_18314799 0.198 ENST00000481914.2
RAB3A
RAB3A, member RAS oncogene family
chr5_+_133450365 0.198 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7




transcription factor 7 (T-cell specific, HMG-box)




chr8_-_60031762 0.197 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr11_-_110583451 0.195 ENST00000260283.4
ENST00000528829.1
ARHGAP20

Rho GTPase activating protein 20

chr1_+_169075554 0.195 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_-_45935663 0.195 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C







zinc finger and BTB domain containing 7C







chr1_+_6845384 0.194 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr2_-_183903133 0.193 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr19_+_18496957 0.193 ENST00000252809.3
GDF15
growth differentiation factor 15
chr1_+_64239657 0.193 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr5_-_55529115 0.193 ENST00000513241.2
ENST00000341048.4
ANKRD55

ankyrin repeat domain 55

chr10_-_21786179 0.193 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr17_+_38599693 0.191 ENST00000542955.1
ENST00000269593.4
IGFBP4

insulin-like growth factor binding protein 4

chr5_-_141257954 0.191 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr7_+_94536514 0.190 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr20_-_23030296 0.190 ENST00000377103.2
THBD
thrombomodulin
chr12_+_71833550 0.189 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr11_+_72929402 0.188 ENST00000393596.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr16_-_65155979 0.187 ENST00000562325.1
ENST00000268603.4
CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

chr14_+_75894391 0.187 ENST00000419727.2
JDP2
Jun dimerization protein 2
chr11_-_1785139 0.186 ENST00000236671.2
CTSD
cathepsin D
chr6_+_45390222 0.185 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr4_-_149365827 0.183 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr9_+_135037334 0.183 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2



netrin G2



chr7_-_103629963 0.182 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr1_-_16556038 0.180 ENST00000375605.2
C1orf134
chromosome 1 open reading frame 134
chr18_-_59561417 0.178 ENST00000591306.1
RNF152
ring finger protein 152
chr7_-_99764853 0.178 ENST00000411994.1
ENST00000426974.2
GAL3ST4

galactose-3-O-sulfotransferase 4

chr17_-_16395328 0.178 ENST00000470794.1
FAM211A
family with sequence similarity 211, member A
chr12_-_49318715 0.177 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr16_+_222846 0.177 ENST00000251595.6
ENST00000397806.1
HBA2

hemoglobin, alpha 2

chr19_+_35739897 0.176 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR


lipolysis stimulated lipoprotein receptor


chr11_-_70672645 0.176 ENST00000423696.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr9_-_114361919 0.175 ENST00000422125.1
PTGR1
prostaglandin reductase 1
chr5_+_178450753 0.175 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
ZNF879


zinc finger protein 879



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0006566 threonine metabolic process(GO:0006566)
0.2 0.9 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 3.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.1 1.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.6 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.3 GO:1990709 maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.1 0.3 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.6 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 1.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.1 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.1 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.1 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.1 0.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.1 0.3 GO:2001076 thorax and anterior abdomen determination(GO:0007356) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.7 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.2 GO:1990641 response to iron ion starvation(GO:1990641)
0.1 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.1 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1 0.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of peroxidase activity(GO:2000468)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.0 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.7 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.0 0.3 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.2 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0003404 optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.0 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.0 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.0 0.0 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0009062 fatty acid catabolic process(GO:0009062) monocarboxylic acid catabolic process(GO:0072329)
0.0 0.1 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.0 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.3 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.0 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.0 0.2 GO:0051608 histamine transport(GO:0051608)
0.0 0.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.0 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.0 GO:0060922 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.0 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.9 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.0 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.0 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.0 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.2 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.7 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 3.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 1.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.5 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.2 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
0.1 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:1990175 EH domain binding(GO:1990175)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.0 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 1.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.0 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 3.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.0 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.9 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.0 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins