Motif ID: KLF7

Z-value: 0.146


Transcription factors associated with KLF7:

Gene SymbolEntrez IDGene Name
KLF7 ENSG00000118263.10 KLF7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208031943_208031991-0.442.4e-01Click!


Activity profile for motif KLF7.

activity profile for motif KLF7


Sorted Z-values histogram for motif KLF7

Sorted Z-values for motif KLF7



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_178865887 0.073 ENST00000477735.1
 PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr17_-_19281203 0.051 ENST00000487415.2
 B9D1
B9 protein domain 1
chr3_-_178865747 0.046 ENST00000435560.1
 RP11-360P21.2
RP11-360P21.2
chr6_+_31865552 0.027 ENST00000469372.1
ENST00000497706.1
 C2

complement component 2

chr16_+_31539183 0.023 ENST00000302312.4
 AHSP
alpha hemoglobin stabilizing protein
chr17_-_48277552 0.021 ENST00000507689.1
 COL1A1
collagen, type I, alpha 1
chr8_+_17104401 0.019 ENST00000324815.3
ENST00000518038.1
 VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr9_-_35812140 0.019 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
 SPAG8


sperm associated antigen 8


chr15_+_92937144 0.016 ENST00000539113.1
ENST00000555434.1
 ST8SIA2

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

chr17_+_41476327 0.015 ENST00000320033.4
 ARL4D
ADP-ribosylation factor-like 4D
chr8_+_17104539 0.015 ENST00000521829.1
ENST00000521005.1
 VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr15_+_74422585 0.014 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
 ISLR2


immunoglobulin superfamily containing leucine-rich repeat 2


chr8_+_72587535 0.014 ENST00000519840.1
ENST00000521131.1
 RP11-1144P22.1

RP11-1144P22.1

chr8_+_115294296 0.013 ENST00000521523.1
ENST00000523682.1
ENST00000507929.2
ENST00000520543.1
ENST00000519248.1
 RP11-267L5.1




RP11-267L5.1




chr3_+_178866199 0.013 ENST00000263967.3
 PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr6_+_30585486 0.013 ENST00000259873.4
ENST00000506373.2
 MRPS18B

mitochondrial ribosomal protein S18B

chr6_-_30585009 0.013 ENST00000376511.2
 PPP1R10
protein phosphatase 1, regulatory subunit 10
chr16_-_65268795 0.013 ENST00000565901.1
ENST00000567058.1
 RP11-256I9.2

RP11-256I9.2

chr2_-_188430478 0.012 ENST00000421427.1
 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_-_39390440 0.012 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2


sirtuin 2


chr19_-_39390350 0.012 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2


sirtuin 2


chr14_+_38660185 0.011 ENST00000555655.1
 CTD-2142D14.1
CTD-2142D14.1
chr5_+_141348721 0.011 ENST00000507163.1
ENST00000394519.1
 RNF14

ring finger protein 14

chr5_+_141348598 0.009 ENST00000394520.2
ENST00000347642.3
 RNF14

ring finger protein 14

chr3_+_183817967 0.009 ENST00000335304.2
ENST00000431041.1
ENST00000436361.2
ENST00000440596.2
 HTR3E



5-hydroxytryptamine (serotonin) receptor 3E, ionotropic



chr1_-_6453426 0.008 ENST00000545482.1
 ACOT7
acyl-CoA thioesterase 7
chr17_-_46894576 0.008 ENST00000393382.3
 TTLL6
tubulin tyrosine ligase-like family, member 6
chr1_-_6453399 0.008 ENST00000608083.1
 ACOT7
acyl-CoA thioesterase 7
chr17_+_38375574 0.008 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
 WIPF2



WAS/WASL interacting protein family, member 2



chr19_-_39390212 0.008 ENST00000437828.1
 SIRT2
sirtuin 2
chr3_-_105587879 0.008 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr19_+_39390587 0.007 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB



nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta



chr5_+_173315283 0.007 ENST00000265085.5
 CPEB4
cytoplasmic polyadenylation element binding protein 4
chr6_+_43603552 0.007 ENST00000372171.4
 MAD2L1BP
MAD2L1 binding protein
chr20_-_2821271 0.007 ENST00000448755.1
ENST00000360652.2
 PCED1A

PC-esterase domain containing 1A

chr20_-_2821756 0.006 ENST00000356872.3
ENST00000439542.1
 PCED1A

PC-esterase domain containing 1A

chr5_+_176560007 0.006 ENST00000510954.1
ENST00000354179.4
 NSD1

nuclear receptor binding SET domain protein 1

chr19_+_58011258 0.006 ENST00000593916.1
ENST00000598770.1
ENST00000599847.1
ENST00000282292.4
 ZNF773



zinc finger protein 773



chr19_-_40931891 0.006 ENST00000357949.4
 SERTAD1
SERTA domain containing 1
chr17_+_38375528 0.005 ENST00000583268.1
 WIPF2
WAS/WASL interacting protein family, member 2
chr19_-_14629224 0.005 ENST00000254322.2
 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr3_-_105588231 0.004 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr6_-_33239712 0.004 ENST00000436044.2
 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_-_33239612 0.004 ENST00000482399.1
ENST00000445902.2
 VPS52

vacuolar protein sorting 52 homolog (S. cerevisiae)

chr8_-_17104356 0.004 ENST00000361272.4
ENST00000523917.1
 CNOT7

CCR4-NOT transcription complex, subunit 7

chr13_-_111522162 0.003 ENST00000538077.1
 LINC00346
long intergenic non-protein coding RNA 346
chr3_+_105085734 0.003 ENST00000306107.5
 ALCAM
activated leukocyte cell adhesion molecule
chr16_+_20499024 0.003 ENST00000593357.1
 AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr1_-_19229218 0.002 ENST00000432718.1
 ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr17_+_73008755 0.002 ENST00000584208.1
ENST00000301585.5
 ICT1

immature colon carcinoma transcript 1

chr1_-_21503337 0.002 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
 EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr6_+_33239787 0.002 ENST00000439602.2
ENST00000474973.1
 RPS18

ribosomal protein S18

chr1_-_21948906 0.002 ENST00000374761.2
ENST00000599760.1
 RAP1GAP

RAP1 GTPase activating protein

chr7_+_27779714 0.002 ENST00000265393.6
ENST00000409980.1
ENST00000433216.2
ENST00000396319.2
 TAX1BP1



Tax1 (human T-cell leukemia virus type I) binding protein 1



chr9_+_130565568 0.002 ENST00000423577.1
 FPGS
folylpolyglutamate synthase
chr15_+_96873921 0.002 ENST00000394166.3
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr20_+_2821366 0.002 ENST00000453689.1
ENST00000417508.1
 VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr1_-_19229248 0.001 ENST00000375341.3
 ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr20_+_2821340 0.001 ENST00000380445.3
ENST00000380469.3
 VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr9_+_130565487 0.001 ENST00000373225.3
ENST00000431857.1
 FPGS

folylpolyglutamate synthase

chr17_-_42462688 0.001 ENST00000377068.3
 ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr1_-_19229014 0.001 ENST00000538839.1
ENST00000290597.5
 ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr1_+_28157273 0.000 ENST00000311772.5
ENST00000236412.7
ENST00000373931.4
 PPP1R8


protein phosphatase 1, regulatory subunit 8


chr9_+_130565147 0.000 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
 FPGS



folylpolyglutamate synthase



chr17_+_18218587 0.000 ENST00000406438.3
 SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr19_+_39390320 0.000 ENST00000576510.1
 NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.0 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)