Motif ID: KLF6

Z-value: 0.364


Transcription factors associated with KLF6:

Gene SymbolEntrez IDGene Name
KLF6 ENSG00000067082.10 KLF6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827417_38274730.809.0e-03Click!


Activity profile for motif KLF6.

activity profile for motif KLF6


Sorted Z-values histogram for motif KLF6

Sorted Z-values for motif KLF6



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_96184533 0.544 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr12_-_96184913 0.537 ENST00000538383.1
NTN4
netrin 4
chr2_+_42275153 0.350 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr1_-_111746966 0.350 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr1_+_169075554 0.313 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr6_-_94129244 0.306 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr2_-_135476552 0.305 ENST00000281924.6
TMEM163
transmembrane protein 163
chr19_+_16435625 0.302 ENST00000248071.5
ENST00000592003.1
KLF2

Kruppel-like factor 2

chr1_-_6321035 0.285 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr6_+_19837592 0.279 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr7_-_100493482 0.239 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE



acetylcholinesterase (Yt blood group)



chr2_+_7005959 0.231 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr5_+_109025067 0.229 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr17_-_39942940 0.216 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP



junction plakoglobin



chr8_-_110656995 0.209 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr6_-_31697563 0.201 ENST00000375789.2
ENST00000416410.1
DDAH2

dimethylarginine dimethylaminohydrolase 2

chr1_-_22263790 0.199 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr21_-_28217721 0.193 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr14_-_23451845 0.192 ENST00000262713.2
AJUBA
ajuba LIM protein
chr11_-_65816591 0.192 ENST00000312006.4
GAL3ST3
galactose-3-O-sulfotransferase 3
chr2_-_170219037 0.188 ENST00000443831.1
LRP2
low density lipoprotein receptor-related protein 2
chr19_+_54412517 0.185 ENST00000391767.1
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr17_-_1928621 0.181 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr4_-_36246060 0.178 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_40631859 0.174 ENST00000295971.7
ENST00000319592.4
RBM47

RNA binding motif protein 47

chr18_+_3449695 0.174 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr18_+_3449821 0.171 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1


TGFB-induced factor homeobox 1


chr9_-_130742792 0.165 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr1_-_44497118 0.164 ENST00000537678.1
ENST00000466926.1
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr3_+_184032313 0.163 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1








eukaryotic translation initiation factor 4 gamma, 1








chr3_-_167813672 0.162 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr14_-_23451467 0.162 ENST00000361265.4
ENST00000555074.1
AJUBA
RP11-298I3.5
ajuba LIM protein
RP11-298I3.5
chr3_-_167813132 0.159 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr3_+_184032283 0.158 ENST00000346169.2
ENST00000414031.1
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr1_-_44497024 0.157 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr6_-_31697977 0.154 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_+_4153598 0.151 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3




cAMP responsive element binding protein 3-like 3




chr22_-_38484922 0.147 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr11_+_57365150 0.145 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr3_-_170626418 0.140 ENST00000474096.1
ENST00000295822.2
EIF5A2

eukaryotic translation initiation factor 5A2

chr11_+_48002279 0.140 ENST00000534219.1
ENST00000527952.1
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr12_+_56473628 0.136 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr2_-_219925189 0.135 ENST00000295731.6
IHH
indian hedgehog
chr3_-_171178157 0.134 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr5_+_133861339 0.134 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr3_-_184079382 0.133 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
CLCN2




chloride channel, voltage-sensitive 2




chr6_+_83073952 0.131 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr3_-_170626376 0.130 ENST00000487522.1
ENST00000474417.1
EIF5A2

eukaryotic translation initiation factor 5A2

chr2_+_10442993 0.130 ENST00000423674.1
ENST00000307845.3
HPCAL1

hippocalcin-like 1

chr7_-_107643567 0.129 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1


laminin, beta 1


chr3_+_50192457 0.127 ENST00000414301.1
ENST00000450338.1
SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

chr1_+_6845578 0.127 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr8_-_8243968 0.127 ENST00000520004.1
SGK223
Tyrosine-protein kinase SgK223
chr10_+_23983671 0.127 ENST00000376462.1
KIAA1217
KIAA1217
chr11_-_94964354 0.126 ENST00000536441.1
SESN3
sestrin 3
chr6_-_33285505 0.124 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr1_-_11863171 0.123 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_11863571 0.121 ENST00000376583.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr2_+_241375069 0.121 ENST00000264039.2
GPC1
glypican 1
chr17_-_16395328 0.120 ENST00000470794.1
FAM211A
family with sequence similarity 211, member A
chr3_+_50712672 0.116 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr17_+_45771420 0.114 ENST00000578982.1
TBKBP1
TBK1 binding protein 1
chr7_-_107643674 0.114 ENST00000222399.6
LAMB1
laminin, beta 1
chr5_-_94620239 0.112 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr3_+_50192833 0.111 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192499 0.109 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_184079492 0.108 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
POLR2H


polymerase (RNA) II (DNA directed) polypeptide H


chr17_-_73874654 0.108 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr3_-_24536453 0.107 ENST00000453729.2
ENST00000413780.1
THRB

thyroid hormone receptor, beta

chr6_+_44095263 0.103 ENST00000532634.1
TMEM63B
transmembrane protein 63B
chr1_+_6845497 0.102 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr18_+_67068228 0.101 ENST00000382713.5
DOK6
docking protein 6
chr4_-_39529049 0.101 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH


UDP-glucose 6-dehydrogenase


chr2_-_170219079 0.100 ENST00000263816.3
LRP2
low density lipoprotein receptor-related protein 2
chr4_+_88928777 0.100 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr6_+_44095347 0.097 ENST00000323267.6
TMEM63B
transmembrane protein 63B
chr1_+_6845384 0.096 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr5_+_133861790 0.096 ENST00000395003.1
PHF15
jade family PHD finger 2
chr12_+_70760056 0.095 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr4_+_26862313 0.093 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
STIM2


stromal interaction molecule 2


chr9_+_35605274 0.093 ENST00000336395.5
TESK1
testis-specific kinase 1
chr1_-_36023251 0.092 ENST00000426982.2
KIAA0319L
KIAA0319-like
chr6_+_31588478 0.091 ENST00000376007.4
ENST00000376033.2
PRRC2A

proline-rich coiled-coil 2A

chr11_-_94964210 0.090 ENST00000416495.2
ENST00000393234.1
SESN3

sestrin 3

chr8_-_145013711 0.090 ENST00000345136.3
PLEC
plectin
chr10_+_11060004 0.089 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CELF2


CUGBP, Elav-like family member 2


chr6_+_43739697 0.089 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr6_+_31926857 0.088 ENST00000375394.2
ENST00000544581.1
SKIV2L

superkiller viralicidic activity 2-like (S. cerevisiae)

chr6_+_36164487 0.088 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chr3_+_50192537 0.088 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_+_26862400 0.087 ENST00000467011.1
ENST00000412829.2
STIM2

stromal interaction molecule 2

chr1_+_6673745 0.086 ENST00000377648.4
PHF13
PHD finger protein 13
chr17_+_30264014 0.085 ENST00000322652.5
ENST00000580398.1
SUZ12

SUZ12 polycomb repressive complex 2 subunit

chr1_-_11751665 0.085 ENST00000376667.3
ENST00000235310.3
MAD2L2

MAD2 mitotic arrest deficient-like 2 (yeast)

chr17_+_79008940 0.085 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAIAP2







BAI1-associated protein 2







chr5_+_67511524 0.085 ENST00000521381.1
ENST00000521657.1
PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

chr5_+_180650271 0.084 ENST00000351937.5
ENST00000315073.5
TRIM41

tripartite motif containing 41

chr12_+_10365082 0.084 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr10_+_11059826 0.083 ENST00000450189.1
CELF2
CUGBP, Elav-like family member 2
chr16_+_69599861 0.083 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_+_203879568 0.082 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr17_-_16395455 0.082 ENST00000409083.3
FAM211A
family with sequence similarity 211, member A
chr4_+_4861385 0.080 ENST00000382723.4
MSX1
msh homeobox 1
chr3_+_184032419 0.080 ENST00000352767.3
ENST00000427141.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr14_+_23341513 0.078 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr3_-_24536222 0.078 ENST00000415021.1
ENST00000447875.1
THRB

thyroid hormone receptor, beta

chr3_-_24536253 0.078 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr14_-_62162541 0.078 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr1_-_221915418 0.076 ENST00000323825.3
ENST00000366899.3
DUSP10

dual specificity phosphatase 10

chr20_+_48807351 0.076 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr8_-_38034234 0.076 ENST00000311351.4
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_82462425 0.075 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr6_+_33168189 0.074 ENST00000444757.1
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr11_+_129939779 0.074 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2




amyloid beta (A4) precursor-like protein 2




chr12_+_10365404 0.074 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1





GABA(A) receptor-associated protein like 1





chr3_-_88108212 0.073 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr2_+_48667983 0.073 ENST00000449090.2
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr6_+_41514078 0.073 ENST00000373063.3
ENST00000373060.1
FOXP4

forkhead box P4

chr8_+_26240414 0.072 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr17_-_42277203 0.072 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr14_-_60097297 0.071 ENST00000395090.1
RTN1
reticulon 1
chr6_+_41514305 0.071 ENST00000409208.1
ENST00000373057.3
FOXP4

forkhead box P4

chr2_+_48667898 0.071 ENST00000281394.4
ENST00000294952.8
PPP1R21

protein phosphatase 1, regulatory subunit 21

chr17_+_38498594 0.070 ENST00000394081.3
RARA
retinoic acid receptor, alpha
chr1_-_36022979 0.070 ENST00000469892.1
ENST00000325722.3
KIAA0319L

KIAA0319-like

chr4_+_26862431 0.070 ENST00000465503.1
STIM2
stromal interaction molecule 2
chr4_-_40632140 0.069 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr17_-_28257080 0.069 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2




slingshot protein phosphatase 2




chr8_-_38034192 0.068 ENST00000520755.1
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_60097524 0.068 ENST00000342503.4
RTN1
reticulon 1
chr19_-_40931891 0.068 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr16_+_69600058 0.068 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_129939811 0.067 ENST00000345598.5
ENST00000338167.5
APLP2

amyloid beta (A4) precursor-like protein 2

chr1_+_36023035 0.067 ENST00000373253.3
NCDN
neurochondrin
chr7_-_72936608 0.066 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr17_+_27071002 0.066 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4



TNF receptor-associated factor 4



chr5_-_159739483 0.066 ENST00000519673.1
ENST00000541762.1
CCNJL

cyclin J-like

chr16_+_69600209 0.066 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_76921459 0.066 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr14_-_82000140 0.066 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr2_+_150187020 0.065 ENST00000334166.4
LYPD6
LY6/PLAUR domain containing 6
chr6_+_127439749 0.065 ENST00000356698.4
RSPO3
R-spondin 3
chr4_+_184426147 0.064 ENST00000302327.3
ING2
inhibitor of growth family, member 2
chr14_+_23340822 0.064 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr2_+_111878483 0.064 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11




BCL2-like 11 (apoptosis facilitator)




chrX_+_56590002 0.064 ENST00000338222.5
UBQLN2
ubiquilin 2
chr2_+_219433588 0.064 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr6_+_37787704 0.064 ENST00000474522.1
ZFAND3
zinc finger, AN1-type domain 3
chr17_+_46131912 0.063 ENST00000584634.1
ENST00000580050.1
NFE2L1

nuclear factor, erythroid 2-like 1

chr12_+_57482665 0.063 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr17_+_37026284 0.062 ENST00000433206.2
ENST00000435347.3
LASP1

LIM and SH3 protein 1

chr9_-_120177342 0.061 ENST00000361209.2
ASTN2
astrotactin 2
chr17_+_46132037 0.061 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1


nuclear factor, erythroid 2-like 1


chr17_-_36956155 0.061 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr17_+_42264556 0.061 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2



transmembrane and ubiquitin-like domain containing 2



chr17_+_38465441 0.061 ENST00000577646.1
ENST00000254066.5
RARA

retinoic acid receptor, alpha

chr8_-_145018905 0.061 ENST00000398774.2
PLEC
plectin
chr5_-_159739532 0.060 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL


cyclin J-like


chr8_-_101322132 0.060 ENST00000523481.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr2_-_211036051 0.059 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chr16_+_75033210 0.059 ENST00000566250.1
ENST00000567962.1
ZNRF1

zinc and ring finger 1, E3 ubiquitin protein ligase

chr17_-_27277615 0.059 ENST00000583747.1
ENST00000584236.1
PHF12

PHD finger protein 12

chr6_+_36165133 0.059 ENST00000446974.1
ENST00000454960.1
BRPF3

bromodomain and PHD finger containing, 3

chr4_-_76598296 0.058 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr4_-_76598326 0.058 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr14_+_23790655 0.057 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr7_-_72936531 0.057 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr2_-_27341966 0.057 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
CGREF1


cell growth regulator with EF-hand domain 1


chr6_-_31864977 0.056 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr12_+_112451120 0.056 ENST00000261735.3
ENST00000455836.1
ERP29

endoplasmic reticulum protein 29

chr16_+_69599899 0.056 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_-_153857819 0.056 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr5_-_81046904 0.056 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr18_+_60190226 0.056 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr19_+_48673949 0.055 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr6_-_44095183 0.055 ENST00000372014.3
MRPL14
mitochondrial ribosomal protein L14
chr1_+_87797351 0.055 ENST00000370542.1
LMO4
LIM domain only 4
chr17_+_46131843 0.054 ENST00000577411.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr5_-_159546396 0.054 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A


PWWP domain containing 2A


chr2_-_159313214 0.053 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148


coiled-coil domain containing 148


chr17_+_47572647 0.053 ENST00000172229.3
NGFR
nerve growth factor receptor
chr14_+_23790690 0.053 ENST00000556821.1
PABPN1
poly(A) binding protein, nuclear 1
chr5_-_142782862 0.053 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_+_53164956 0.053 ENST00000563410.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_129592471 0.053 ENST00000473814.2
ENST00000490974.1
UBE2H

ubiquitin-conjugating enzyme E2H

chr13_-_45151259 0.052 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr17_+_34136459 0.052 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15





TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa





chr10_+_105253661 0.052 ENST00000369780.4
NEURL
neuralized E3 ubiquitin protein ligase 1
chr1_-_113615699 0.052 ENST00000421157.1
RP11-31F15.2
RP11-31F15.2
chr16_+_75032901 0.051 ENST00000335325.4
ENST00000320619.6
ZNRF1

zinc and ring finger 1, E3 ubiquitin protein ligase

chr5_-_78281623 0.051 ENST00000521117.1
ARSB
arylsulfatase B
chr17_+_42264395 0.051 ENST00000587989.1
ENST00000590235.1
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr8_+_74206829 0.050 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr4_-_77819002 0.050 ENST00000334306.2
SOWAHB
sosondowah ankyrin repeat domain family member B
chr1_+_154297988 0.050 ENST00000368487.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr9_-_95896550 0.049 ENST00000375446.4
NINJ1
ninjurin 1
chr5_-_81046841 0.049 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2


single-stranded DNA binding protein 2


chr12_-_51477333 0.049 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2



cysteine-serine-rich nuclear protein 2



chr6_-_32157947 0.049 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr17_-_60885645 0.049 ENST00000544856.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.3 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.4 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.0 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.3 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.4 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.0 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.0 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043257 laminin-8 complex(GO:0043257)
0.1 0.2 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.2 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling