Motif ID: KLF3

Z-value: 0.482


Transcription factors associated with KLF3:

Gene SymbolEntrez IDGene Name
KLF3 ENSG00000109787.8 KLF3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_38665827-0.284.6e-01Click!


Activity profile for motif KLF3.

activity profile for motif KLF3


Sorted Z-values histogram for motif KLF3

Sorted Z-values for motif KLF3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_43968306 1.038 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr13_-_46785977 0.552 ENST00000442275.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_+_39968926 0.501 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10


FK506 binding protein 10, 65 kDa


chr17_+_38171681 0.438 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3



colony stimulating factor 3 (granulocyte)



chrX_+_151883090 0.435 ENST00000370293.2
ENST00000423993.1
ENST00000447530.1
ENST00000458057.1
ENST00000331220.2
ENST00000422085.1
ENST00000453150.1
ENST00000409560.1
MAGEA2B







melanoma antigen family A, 2B







chrX_-_152486108 0.412 ENST00000356661.5
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chrX_-_151938171 0.369 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
MAGEA3


melanoma antigen family A, 3


chr15_-_74659978 0.340 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1


cytochrome P450, family 11, subfamily A, polypeptide 1


chr14_+_63671577 0.323 ENST00000555125.1
RHOJ
ras homolog family member J
chr17_+_38171614 0.303 ENST00000583218.1
ENST00000394149.3
CSF3

colony stimulating factor 3 (granulocyte)

chr20_+_2795626 0.297 ENST00000603872.1
ENST00000380589.4
C20orf141

chromosome 20 open reading frame 141

chr14_+_96087251 0.274 ENST00000555032.1
RP11-1070N10.5
RP11-1070N10.5
chr14_+_63671105 0.265 ENST00000316754.3
RHOJ
ras homolog family member J
chr5_-_138842286 0.264 ENST00000515823.1
ECSCR
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr20_+_61924532 0.247 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
COL20A1


collagen, type XX, alpha 1


chr12_-_55378452 0.242 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr9_+_138413277 0.223 ENST00000263598.2
ENST00000371781.3
LCN1

lipocalin 1

chr1_-_159869912 0.220 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr22_+_31523734 0.220 ENST00000402238.1
ENST00000404453.1
ENST00000401755.1
INPP5J


inositol polyphosphate-5-phosphatase J


chr16_+_66638003 0.216 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3





CKLF-like MARVEL transmembrane domain containing 3





chr22_+_21321531 0.214 ENST00000405089.1
ENST00000335375.5
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr15_-_61521495 0.208 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr12_-_55378470 0.208 ENST00000524668.1
ENST00000533607.1
TESPA1

thymocyte expressed, positive selection associated 1

chr12_-_62653903 0.199 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr12_+_72667203 0.195 ENST00000547300.1
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr20_+_44637526 0.193 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr20_+_61299155 0.190 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr1_+_16083123 0.186 ENST00000510393.1
ENST00000430076.1
FBLIM1

filamin binding LIM protein 1

chr20_+_61287711 0.184 ENST00000370507.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr9_+_112403059 0.183 ENST00000374531.2
PALM2
paralemmin 2
chr2_-_74776586 0.176 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr8_-_133493200 0.176 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr5_+_135385202 0.175 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr7_-_25219897 0.170 ENST00000283905.3
ENST00000409280.1
ENST00000415598.1
C7orf31


chromosome 7 open reading frame 31


chr19_-_35992780 0.162 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr1_+_16083098 0.161 ENST00000496928.2
ENST00000508310.1
FBLIM1

filamin binding LIM protein 1

chr13_+_100634004 0.158 ENST00000376335.3
ZIC2
Zic family member 2
chr20_+_31499459 0.155 ENST00000439060.1
EFCAB8
EF-hand calcium binding domain 8
chr22_-_20138302 0.152 ENST00000540078.1
ENST00000439765.2
AC006547.14

uncharacterized protein LOC388849

chr9_+_112403088 0.151 ENST00000448454.2
PALM2
paralemmin 2
chr12_+_7169887 0.150 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr15_-_72612470 0.149 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr16_-_1843720 0.148 ENST00000415638.3
ENST00000215539.3
IGFALS

insulin-like growth factor binding protein, acid labile subunit

chrX_-_71526999 0.146 ENST00000453707.2
ENST00000373619.3
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr7_-_99573677 0.143 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr5_+_86415919 0.142 ENST00000515750.1
RP11-72L22.1
RP11-72L22.1
chr17_+_79859985 0.141 ENST00000333383.7
NPB
neuropeptide B
chr12_+_50451331 0.138 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr2_+_74881398 0.137 ENST00000339773.5
ENST00000434486.1
SEMA4F

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F

chr17_-_27188984 0.137 ENST00000582320.2
MIR144
microRNA 451b
chr16_+_56385290 0.137 ENST00000564727.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr13_-_33002279 0.136 ENST00000380130.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr22_+_21321447 0.135 ENST00000434714.1
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr4_+_7940728 0.132 ENST00000429019.3
AC097381.1
AC097381.1
chr11_-_107582775 0.131 ENST00000305991.2
SLN
sarcolipin
chr15_-_76005170 0.130 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr1_+_16083154 0.128 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr16_+_89696692 0.127 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chrX_-_71526813 0.126 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chrX_+_133941218 0.126 ENST00000370784.4
ENST00000370785.3
FAM122C

family with sequence similarity 122C

chr2_-_74782817 0.125 ENST00000413469.1
LOXL3
lysyl oxidase-like 3
chr17_+_7323634 0.123 ENST00000323675.3
SPEM1
spermatid maturation 1
chr2_+_74881432 0.123 ENST00000453930.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr3_+_54156664 0.122 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr15_+_40643227 0.121 ENST00000448599.2
PHGR1
proline/histidine/glycine-rich 1
chr2_+_211342400 0.119 ENST00000417946.1
ENST00000518043.1
ENST00000523702.1
CPS1


carbamoyl-phosphate synthase 1, mitochondrial


chr11_-_65793948 0.119 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr7_-_752577 0.117 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B



protein kinase, cAMP-dependent, regulatory, type I, beta



chr22_-_22874610 0.115 ENST00000302097.3
ZNF280A
zinc finger protein 280A
chr15_+_91427726 0.115 ENST00000452243.1
FES
feline sarcoma oncogene
chr2_+_85132749 0.115 ENST00000233143.4
TMSB10
thymosin beta 10
chr12_+_121088291 0.114 ENST00000351200.2
CABP1
calcium binding protein 1
chr1_-_206671061 0.113 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr15_+_91427642 0.113 ENST00000328850.3
ENST00000414248.2
FES

feline sarcoma oncogene

chr3_+_157261116 0.112 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55




chromosome 3 open reading frame 55




chr17_-_42019836 0.111 ENST00000225992.3
PPY
pancreatic polypeptide
chr1_-_166944652 0.111 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
ILDR2





immunoglobulin-like domain containing receptor 2





chr9_-_140196703 0.110 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr13_+_102104952 0.108 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr18_+_6729698 0.108 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr11_-_64764435 0.108 ENST00000534177.1
ENST00000301887.4
BATF2

basic leucine zipper transcription factor, ATF-like 2

chr2_+_74881355 0.106 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chrX_+_70364667 0.105 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3



neuroligin 3



chr14_-_67955426 0.104 ENST00000554480.1
TMEM229B
transmembrane protein 229B
chr12_-_66317967 0.103 ENST00000601398.1
AC090673.2
Uncharacterized protein
chr15_+_75074915 0.102 ENST00000567123.1
ENST00000569462.1
CSK

c-src tyrosine kinase

chr1_+_2004901 0.102 ENST00000400921.2
PRKCZ
protein kinase C, zeta
chr8_-_122653630 0.101 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr6_-_133035185 0.099 ENST00000367928.4
VNN1
vanin 1
chr16_+_66637777 0.097 ENST00000563672.1
ENST00000424011.2
CMTM3

CKLF-like MARVEL transmembrane domain containing 3

chr11_+_59705928 0.095 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr18_+_6729725 0.093 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chr15_+_63334831 0.092 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1








tropomyosin 1 (alpha)








chr13_+_52158610 0.092 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr12_+_122326662 0.090 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9


proteasome (prosome, macropain) 26S subunit, non-ATPase, 9


chr14_-_58332774 0.089 ENST00000556826.1
SLC35F4
solute carrier family 35, member F4
chr1_-_23521222 0.088 ENST00000374619.1
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr12_-_81331460 0.088 ENST00000549417.1
LIN7A
lin-7 homolog A (C. elegans)
chr10_-_113943447 0.088 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM


glycerol-3-phosphate acyltransferase, mitochondrial


chr3_+_37903432 0.087 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr12_-_56236690 0.087 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr11_+_65647280 0.087 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
CTSW


cathepsin W


chr11_-_6426635 0.087 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1


amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)


chr3_-_127542051 0.086 ENST00000398104.1
MGLL
monoglyceride lipase
chr3_+_51976338 0.086 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
PARP3


poly (ADP-ribose) polymerase family, member 3


chrX_-_153210107 0.085 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
RENBP


renin binding protein


chr15_+_91427691 0.084 ENST00000559355.1
ENST00000394302.1
FES

feline sarcoma oncogene

chr3_+_54156570 0.084 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr19_-_14016877 0.084 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57


chromosome 19 open reading frame 57


chr12_+_52445191 0.082 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chrX_-_153151586 0.082 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM


L1 cell adhesion molecule


chr17_+_6939362 0.081 ENST00000308027.6
SLC16A13
solute carrier family 16, member 13
chr10_+_89124746 0.081 ENST00000465545.1
NUTM2D
NUT family member 2D
chr11_+_60691924 0.080 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A


transmembrane protein 132A


chr13_-_33002151 0.079 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
N4BP2L1




NEDD4 binding protein 2-like 1




chr3_-_25706368 0.079 ENST00000424225.1
TOP2B
topoisomerase (DNA) II beta 180kDa
chr16_+_1290694 0.077 ENST00000338844.3
TPSAB1
tryptase alpha/beta 1
chr3_-_49449350 0.076 ENST00000454011.2
ENST00000445425.1
ENST00000422781.1
RHOA


ras homolog family member A


chr1_-_166028709 0.076 ENST00000595430.1
AL626787.1
AL626787.1
chr13_+_102104980 0.076 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_+_122326630 0.075 ENST00000541212.1
ENST00000340175.5
PSMD9

proteasome (prosome, macropain) 26S subunit, non-ATPase, 9

chr19_-_12945362 0.073 ENST00000590404.1
ENST00000592204.1
RTBDN

retbindin

chrX_-_153141302 0.073 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM




L1 cell adhesion molecule




chr4_+_9174899 0.072 ENST00000432515.1
FAM90A26
family with sequence similarity 90, member A26
chr22_+_39760130 0.071 ENST00000381535.4
SYNGR1
synaptogyrin 1
chr1_+_2005126 0.070 ENST00000495347.1
PRKCZ
protein kinase C, zeta
chr3_-_49449521 0.070 ENST00000431929.1
ENST00000418115.1
RHOA

ras homolog family member A

chr17_+_6926339 0.070 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr17_-_39968855 0.070 ENST00000355468.3
ENST00000590496.1
LEPREL4

leprecan-like 4

chr21_-_35773370 0.069 ENST00000410005.1
AP000322.54
chromosome 21 open reading frame 140
chr6_+_35744367 0.069 ENST00000360454.2
ENST00000403376.3
CLPSL2

colipase-like 2

chr19_-_22806764 0.069 ENST00000598042.1
AC011516.2
AC011516.2
chr12_+_52404270 0.068 ENST00000552049.1
ENST00000546756.1
GRASP

GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

chr11_-_58980342 0.067 ENST00000361050.3
MPEG1
macrophage expressed 1
chr6_+_126661253 0.067 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW


centromere protein W


chr19_+_36157715 0.066 ENST00000379013.2
ENST00000222275.2
UPK1A

uroplakin 1A

chr6_+_158244223 0.066 ENST00000392185.3
SNX9
sorting nexin 9
chr18_-_67629015 0.065 ENST00000579496.1
CD226
CD226 molecule
chr11_-_117699413 0.065 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr3_-_196065374 0.065 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chr15_+_75303993 0.064 ENST00000564779.1
SCAMP5
secretory carrier membrane protein 5
chr20_-_1600642 0.064 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
SIRPB1



RP4-576H24.4
signal-regulatory protein beta 1



Uncharacterized protein
chr15_-_83876758 0.064 ENST00000299633.4
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr8_-_10512569 0.063 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr9_+_128509663 0.063 ENST00000373489.5
ENST00000373483.2
PBX3

pre-B-cell leukemia homeobox 3

chr1_+_151030234 0.062 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_+_36192758 0.061 ENST00000242108.4
EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr5_-_54468974 0.061 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B




cell division cycle 20B




chr15_+_81591757 0.060 ENST00000558332.1
IL16
interleukin 16
chr7_+_31092109 0.060 ENST00000409363.1
ADCYAP1R1
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
chr19_-_5784610 0.060 ENST00000390672.2
ENST00000419421.2
PRR22

proline rich 22

chr6_-_150067632 0.060 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
NUP43


nucleoporin 43kDa


chr15_+_81589254 0.060 ENST00000394652.2
IL16
interleukin 16
chr10_+_88414298 0.060 ENST00000372071.2
OPN4
opsin 4
chr17_-_8198636 0.060 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35


solute carrier family 25, member 35


chr7_+_116165754 0.059 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr5_-_43313574 0.059 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr11_+_118826999 0.059 ENST00000264031.2
UPK2
uroplakin 2
chrX_-_71933888 0.058 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1




phosphorylase kinase, alpha 1 (muscle)




chr15_+_75074385 0.058 ENST00000220003.9
CSK
c-src tyrosine kinase
chr16_+_1290725 0.058 ENST00000461509.2
TPSAB1
tryptase alpha/beta 1
chr19_+_41860047 0.057 ENST00000604123.1
TMEM91
transmembrane protein 91
chr13_-_99630233 0.057 ENST00000376460.1
ENST00000442173.1
DOCK9

dedicator of cytokinesis 9

chr12_-_57634475 0.057 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr7_+_150434430 0.057 ENST00000358647.3
GIMAP5
GTPase, IMAP family member 5
chr3_-_196065248 0.056 ENST00000446879.1
ENST00000273695.3
TM4SF19

transmembrane 4 L six family member 19

chr21_-_46348626 0.056 ENST00000517563.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr15_+_75074410 0.055 ENST00000439220.2
CSK
c-src tyrosine kinase
chr1_-_63153944 0.055 ENST00000340370.5
ENST00000404627.2
ENST00000251157.5
DOCK7


dedicator of cytokinesis 7


chr14_-_21566731 0.055 ENST00000360947.3
ZNF219
zinc finger protein 219
chr7_+_36192855 0.054 ENST00000534978.1
EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr6_-_150067696 0.054 ENST00000340413.2
ENST00000367403.3
NUP43

nucleoporin 43kDa

chr6_-_35109080 0.054 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
TCP11






t-complex 11, testis-specific






chr2_-_74619152 0.053 ENST00000440727.1
ENST00000409240.1
DCTN1

dynactin 1

chr17_+_56270084 0.053 ENST00000225371.5
EPX
eosinophil peroxidase
chr17_+_7452336 0.053 ENST00000293826.4
TNFSF12-TNFSF13
TNFSF12-TNFSF13 readthrough
chr1_-_238054094 0.053 ENST00000366570.4
ZP4
zona pellucida glycoprotein 4
chr21_-_47738112 0.053 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr1_-_42921915 0.053 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr12_-_95010147 0.052 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr8_+_145734433 0.052 ENST00000301327.4
MFSD3
major facilitator superfamily domain containing 3
chr1_+_2005425 0.052 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr19_-_7553889 0.052 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr11_-_2906979 0.051 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr12_-_31478428 0.051 ENST00000543615.1
FAM60A
family with sequence similarity 60, member A
chr20_+_43803517 0.051 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chrX_-_65858865 0.051 ENST00000374719.3
ENST00000450752.1
ENST00000451436.2
EDA2R


ectodysplasin A2 receptor


chrX_-_71526741 0.050 ENST00000454225.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr2_+_211342432 0.050 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_-_204119009 0.050 ENST00000444817.1
ETNK2
ethanolamine kinase 2
chr3_-_130465604 0.050 ENST00000356763.3
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr16_+_618837 0.049 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr16_+_67233412 0.049 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr15_-_74495188 0.049 ENST00000563965.1
ENST00000395105.4
STRA6

stimulated by retinoic acid 6

chr11_+_119038897 0.049 ENST00000454811.1
ENST00000449394.1
NLRX1

NLR family member X1

chr3_-_109035342 0.049 ENST00000478945.1
DPPA2
developmental pluripotency associated 2
chr1_-_204654481 0.049 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr10_+_94451574 0.048 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr8_+_123793633 0.048 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr16_-_2379688 0.048 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.2 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.3 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 0.1 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.0 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.0 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.0 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion