Motif ID: KLF1

Z-value: 0.564


Transcription factors associated with KLF1:

Gene SymbolEntrez IDGene Name
KLF1 ENSG00000105610.4 KLF1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF1hg19_v2_chr19_-_12997995_12998021-0.078.7e-01Click!


Activity profile for motif KLF1.

activity profile for motif KLF1


Sorted Z-values histogram for motif KLF1

Sorted Z-values for motif KLF1



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_56225248 0.817 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr1_-_161039647 0.656 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039753 0.641 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039456 0.624 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr6_+_43968306 0.518 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr17_+_39969183 0.487 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr17_+_38171681 0.463 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3



colony stimulating factor 3 (granulocyte)



chr17_+_38171614 0.450 ENST00000583218.1
ENST00000394149.3
CSF3

colony stimulating factor 3 (granulocyte)

chr9_-_130616915 0.443 ENST00000344849.3
ENG
endoglin
chr9_-_130617029 0.435 ENST00000373203.4
ENG
endoglin
chr13_-_96296944 0.385 ENST00000361396.2
ENST00000376829.2
DZIP1

DAZ interacting zinc finger protein 1

chr22_-_39639021 0.368 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr17_+_39968926 0.314 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10


FK506 binding protein 10, 65 kDa


chr12_+_54332535 0.288 ENST00000243056.3
HOXC13
homeobox C13
chr2_-_70944855 0.278 ENST00000415348.1
ADD2
adducin 2 (beta)
chr16_-_31161380 0.277 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36


protease, serine, 36


chr5_+_82767583 0.260 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr1_-_166135952 0.243 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr15_-_42386752 0.240 ENST00000290472.3
PLA2G4D
phospholipase A2, group IVD (cytosolic)
chr14_+_21569245 0.238 ENST00000556585.2
TMEM253
transmembrane protein 253
chrX_+_140677562 0.231 ENST00000370518.3
SPANXA2
SPANX family, member A2
chr15_-_61521495 0.229 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr19_-_36004543 0.228 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN


dermokine


chr14_+_24867992 0.216 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr6_+_7541808 0.212 ENST00000379802.3
DSP
desmoplakin
chr19_-_47128294 0.211 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR




prostaglandin I2 (prostacyclin) receptor (IP)




chrX_+_68835911 0.208 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA





ectodysplasin A





chr1_-_166136187 0.205 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr9_-_72287191 0.205 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr12_+_72667203 0.201 ENST00000547300.1
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr2_-_227050079 0.193 ENST00000423838.1
AC068138.1
AC068138.1
chrX_-_153151586 0.183 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM


L1 cell adhesion molecule


chr1_+_153747746 0.177 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr17_+_38673270 0.172 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr15_-_60690163 0.165 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2



















annexin A2



















chr11_-_75379612 0.165 ENST00000526740.1
MAP6
microtubule-associated protein 6
chr14_+_77425972 0.159 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr17_+_7210898 0.158 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr3_-_50383096 0.157 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr17_+_7210852 0.157 ENST00000576930.1
EIF5A
eukaryotic translation initiation factor 5A
chr2_-_74667612 0.153 ENST00000305557.5
ENST00000233330.6
RTKN

rhotekin

chr2_+_75185619 0.151 ENST00000483063.1
POLE4
polymerase (DNA-directed), epsilon 4, accessory subunit
chr13_+_102104952 0.151 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_-_117210290 0.147 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr17_+_7210921 0.146 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chr12_+_57943781 0.146 ENST00000455537.2
ENST00000286452.5
KIF5A

kinesin family member 5A

chr22_-_20138302 0.144 ENST00000540078.1
ENST00000439765.2
AC006547.14

uncharacterized protein LOC388849

chr17_-_39553844 0.142 ENST00000251645.2
KRT31
keratin 31
chr2_+_85132749 0.142 ENST00000233143.4
TMSB10
thymosin beta 10
chrX_+_70503526 0.138 ENST00000413858.1
ENST00000450092.1
NONO

non-POU domain containing, octamer-binding

chrX_-_71526999 0.136 ENST00000453707.2
ENST00000373619.3
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr6_-_131291572 0.136 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chrX_-_71526813 0.134 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr11_-_6426635 0.130 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1


amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)


chr2_+_85360499 0.130 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr20_+_44035200 0.130 ENST00000372717.1
ENST00000360981.4
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr9_+_82267508 0.128 ENST00000490347.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_186080012 0.126 ENST00000544847.1
ENST00000265022.3
DGKG

diacylglycerol kinase, gamma 90kDa

chr12_-_82152444 0.126 ENST00000549325.1
ENST00000550584.2
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr17_+_43972010 0.124 ENST00000334239.8
ENST00000446361.3
MAPT

microtubule-associated protein tau

chr17_-_27188984 0.123 ENST00000582320.2
MIR144
microRNA 451b
chr1_-_55352834 0.123 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr15_-_76005170 0.122 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr17_-_8534067 0.120 ENST00000360416.3
ENST00000269243.4
MYH10

myosin, heavy chain 10, non-muscle

chr17_+_6918354 0.118 ENST00000552775.1
C17orf49
chromosome 17 open reading frame 49
chr12_-_82152420 0.117 ENST00000552948.1
ENST00000548586.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr17_-_8534031 0.117 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
MYH10


myosin, heavy chain 10, non-muscle


chr17_+_18280976 0.117 ENST00000399134.4
EVPLL
envoplakin-like
chr1_-_6526192 0.116 ENST00000377782.3
ENST00000351959.5
ENST00000356876.3
TNFRSF25


tumor necrosis factor receptor superfamily, member 25


chr1_+_35225339 0.116 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chrX_+_70503433 0.115 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO



non-POU domain containing, octamer-binding



chr17_+_7210294 0.114 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chrX_-_39923656 0.114 ENST00000413905.1
BCOR
BCL6 corepressor
chr15_+_90931450 0.114 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQGAP1


IQ motif containing GTPase activating protein 1


chr12_-_82153087 0.113 ENST00000547623.1
ENST00000549396.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr22_+_46449674 0.111 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr1_-_27709793 0.111 ENST00000374027.3
ENST00000374025.3
CD164L2

CD164 sialomucin-like 2

chr1_-_204183071 0.111 ENST00000308302.3
GOLT1A
golgi transport 1A
chrX_+_69672136 0.109 ENST00000374355.3
DLG3
discs, large homolog 3 (Drosophila)
chr3_-_127542021 0.108 ENST00000434178.2
MGLL
monoglyceride lipase
chr7_+_134430212 0.107 ENST00000436461.2
CALD1
caldesmon 1
chr4_-_186682716 0.104 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr11_-_6440624 0.102 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr3_-_49449350 0.100 ENST00000454011.2
ENST00000445425.1
ENST00000422781.1
RHOA


ras homolog family member A


chrX_+_47077680 0.100 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr2_-_61765732 0.099 ENST00000443240.1
ENST00000436018.1
XPO1

exportin 1 (CRM1 homolog, yeast)

chr20_-_31124186 0.099 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr17_+_1633755 0.098 ENST00000545662.1
WDR81
WD repeat domain 81
chr15_+_75074385 0.096 ENST00000220003.9
CSK
c-src tyrosine kinase
chr3_-_49449521 0.092 ENST00000431929.1
ENST00000418115.1
RHOA

ras homolog family member A

chr6_+_41606176 0.092 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI




MyoD family inhibitor




chr17_-_74023474 0.091 ENST00000301607.3
EVPL
envoplakin
chr7_+_100318423 0.089 ENST00000252723.2
EPO
erythropoietin
chr15_+_75074410 0.088 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_+_74212073 0.088 ENST00000441217.1
AC073046.25
AC073046.25
chr15_-_40545111 0.087 ENST00000319503.3
ENST00000559727.1
C15orf56

chromosome 15 open reading frame 56

chr12_-_96793142 0.087 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17


cyclin-dependent kinase 17


chr17_+_65374075 0.086 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_55505184 0.086 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr7_+_30960915 0.085 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1


aquaporin 1 (Colton blood group)


chr17_-_74023291 0.085 ENST00000586740.1
EVPL
envoplakin
chr15_-_64648273 0.084 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1


casein kinase 1, gamma 1


chr17_+_6918064 0.081 ENST00000546760.1
ENST00000552402.1
C17orf49

chromosome 17 open reading frame 49

chr2_+_73441350 0.081 ENST00000389501.4
SMYD5
SMYD family member 5
chr17_+_6918093 0.081 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chrX_-_152989798 0.080 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31



B-cell receptor-associated protein 31



chr11_-_75380165 0.080 ENST00000304771.3
MAP6
microtubule-associated protein 6
chr1_-_6526167 0.080 ENST00000351748.3
ENST00000348333.3
TNFRSF25

tumor necrosis factor receptor superfamily, member 25

chr1_-_159893507 0.078 ENST00000368096.1
TAGLN2
transgelin 2
chr15_-_72521017 0.078 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr1_-_153958805 0.078 ENST00000368575.3
RAB13
RAB13, member RAS oncogene family
chr3_+_155588375 0.078 ENST00000295920.7
GMPS
guanine monphosphate synthase
chr17_-_7080227 0.077 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr17_-_7590745 0.077 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr13_+_102104980 0.076 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_74648848 0.076 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr11_+_278365 0.075 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr6_+_158244223 0.075 ENST00000392185.3
SNX9
sorting nexin 9
chr2_-_64371546 0.074 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr3_-_113465065 0.074 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr6_+_106546808 0.074 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr16_-_31147020 0.074 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8


protease, serine, 8


chr5_-_16617162 0.074 ENST00000306320.9
FAM134B
family with sequence similarity 134, member B
chr1_+_151129103 0.073 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr16_-_30134266 0.072 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3

chr22_+_37959647 0.071 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr7_-_150721570 0.071 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B



autophagy related 9B



chr11_-_6440283 0.070 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1



amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)



chr3_-_71114066 0.070 ENST00000485326.2
FOXP1
forkhead box P1
chr11_+_65647280 0.070 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
CTSW


cathepsin W


chr6_-_83903600 0.070 ENST00000506587.1
ENST00000507554.1
PGM3

phosphoglucomutase 3

chr17_-_39968855 0.069 ENST00000355468.3
ENST00000590496.1
LEPREL4

leprecan-like 4

chr12_+_26274917 0.069 ENST00000538142.1
SSPN
sarcospan
chr17_-_2117600 0.069 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr12_+_110940005 0.068 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B



RAD9 homolog B (S. pombe)



chr12_-_49393092 0.068 ENST00000421952.2
DDN
dendrin
chrX_+_123097014 0.067 ENST00000394478.1
STAG2
stromal antigen 2
chr19_+_41860047 0.067 ENST00000604123.1
TMEM91
transmembrane protein 91
chr2_-_160919112 0.066 ENST00000283243.7
ENST00000392771.1
PLA2R1

phospholipase A2 receptor 1, 180kDa

chr16_-_4466622 0.066 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
CORO7





coronin 7





chr15_-_101142362 0.066 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS





lines homolog (Drosophila)





chr17_-_74707037 0.066 ENST00000355797.3
ENST00000375036.2
ENST00000449428.2
MXRA7


matrix-remodelling associated 7


chr10_+_120967072 0.065 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr17_-_46507567 0.065 ENST00000584924.1
SKAP1
src kinase associated phosphoprotein 1
chr3_-_48632593 0.065 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr7_+_8474150 0.065 ENST00000602349.1
NXPH1
neurexophilin 1
chr11_+_61248583 0.065 ENST00000432063.2
ENST00000338608.2
PPP1R32

protein phosphatase 1, regulatory subunit 32

chrX_+_47077632 0.065 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr1_-_59165763 0.065 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr1_+_16090914 0.065 ENST00000441801.2
FBLIM1
filamin binding LIM protein 1
chr8_-_123793048 0.064 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr3_+_50273625 0.064 ENST00000536647.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_+_49711391 0.064 ENST00000296456.5
ENST00000449966.1
APEH

acylaminoacyl-peptide hydrolase

chr20_-_52687030 0.063 ENST00000411563.1
BCAS1
breast carcinoma amplified sequence 1
chr5_+_173930676 0.063 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr6_-_83902933 0.063 ENST00000512866.1
ENST00000510258.1
ENST00000503094.1
ENST00000283977.4
ENST00000513973.1
ENST00000508748.1
PGM3





phosphoglucomutase 3





chr6_-_41168920 0.063 ENST00000483722.1
TREML2
triggering receptor expressed on myeloid cells-like 2
chr3_-_113464906 0.063 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr15_+_101142722 0.062 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7


ankyrin repeat and SOCS box containing 7


chr2_+_45878790 0.062 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr15_+_63796779 0.062 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3






ubiquitin specific peptidase 3






chr18_+_55712915 0.062 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr19_-_36019123 0.061 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr10_+_94608218 0.061 ENST00000371543.1
EXOC6
exocyst complex component 6
chr7_+_100081542 0.061 ENST00000300179.2
ENST00000423930.1
NYAP1

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1

chr6_+_150070857 0.060 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr15_-_74043816 0.060 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr20_-_50722183 0.060 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr1_-_145589424 0.059 ENST00000334513.5
NUDT17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr16_-_2379688 0.059 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr10_+_99258625 0.059 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr12_-_120663792 0.058 ENST00000546532.1
ENST00000548912.1
PXN

paxillin

chr12_+_122326662 0.057 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9


proteasome (prosome, macropain) 26S subunit, non-ATPase, 9


chr19_-_39340563 0.057 ENST00000601813.1
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chrX_-_140336629 0.057 ENST00000358993.2
SPANXC
SPANX family, member C
chrX_+_56258844 0.056 ENST00000374928.3
KLF8
Kruppel-like factor 8
chr2_-_26205340 0.056 ENST00000264712.3
KIF3C
kinesin family member 3C
chr2_+_172950227 0.055 ENST00000341900.6
DLX1
distal-less homeobox 1
chr6_+_150070831 0.055 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr14_-_21566731 0.055 ENST00000360947.3
ZNF219
zinc finger protein 219
chr9_-_33264557 0.054 ENST00000473781.1
ENST00000488499.1
BAG1

BCL2-associated athanogene

chr15_-_64995399 0.054 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
OAZ2



ornithine decarboxylase antizyme 2



chr19_+_8117636 0.054 ENST00000253451.4
ENST00000315626.4
CCL25

chemokine (C-C motif) ligand 25

chr2_-_74648702 0.054 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr12_-_58131931 0.054 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_130339710 0.053 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr15_+_68115895 0.053 ENST00000554240.1
SKOR1
SKI family transcriptional corepressor 1
chr22_+_31477296 0.052 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN




smoothelin




chr17_+_66287628 0.052 ENST00000581639.1
ENST00000452479.2
ARSG

arylsulfatase G

chr15_-_101142401 0.052 ENST00000314742.8
LINS
lines homolog (Drosophila)
chr9_+_139746792 0.051 ENST00000317446.2
ENST00000445819.1
MAMDC4

MAM domain containing 4

chr9_-_33264676 0.051 ENST00000472232.3
ENST00000379704.2
BAG1

BCL2-associated athanogene

chr12_-_93835665 0.051 ENST00000552442.1
ENST00000550657.1
UBE2N

ubiquitin-conjugating enzyme E2N

chr1_-_117664317 0.050 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
TRIM45


tripartite motif containing 45


chr1_+_203765437 0.050 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_-_7141490 0.050 ENST00000574236.1
ENST00000572789.1
PHF23

PHD finger protein 23

chr19_+_4474846 0.050 ENST00000589486.1
ENST00000592691.1
HDGFRP2

Hepatoma-derived growth factor-related protein 2

chr5_+_140514782 0.049 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr8_+_123793633 0.049 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr17_+_72744791 0.049 ENST00000583369.1
ENST00000262613.5
SLC9A3R1

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.8 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.3 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.4 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.9 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:0021861 forebrain radial glial cell differentiation(GO:0021861) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.3 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0044010 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.8 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005534 galactose binding(GO:0005534)
0.1 0.8 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.0 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.8 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.3 PID_S1P_S1P1_PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.8 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins