Motif ID: ISL2

Z-value: 0.438


Transcription factors associated with ISL2:

Gene SymbolEntrez IDGene Name
ISL2 ENSG00000159556.5 ISL2



Activity profile for motif ISL2.

activity profile for motif ISL2


Sorted Z-values histogram for motif ISL2

Sorted Z-values for motif ISL2



Network of associatons between targets according to the STRING database.



First level regulatory network of ISL2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169013666 0.706 ENST00000359299.3
ANXA10
annexin A10
chr2_-_207078154 0.526 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr7_-_16844611 0.512 ENST00000401412.1
ENST00000419304.2
AGR2

anterior gradient 2

chr2_-_207078086 0.490 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr2_-_190446738 0.458 ENST00000427419.1
ENST00000455320.1
SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

chr7_-_81635106 0.419 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr5_+_32788945 0.418 ENST00000326958.1
AC026703.1
AC026703.1
chr10_-_5046042 0.372 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr21_+_15588499 0.347 ENST00000400577.3
RBM11
RNA binding motif protein 11
chr12_-_95945246 0.279 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr4_+_86525299 0.261 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr8_-_125577940 0.255 ENST00000519168.1
ENST00000395508.2
MTSS1

metastasis suppressor 1

chr2_-_145277569 0.252 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr10_-_128359074 0.211 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr8_+_92261516 0.210 ENST00000276609.3
ENST00000309536.2
SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr8_-_30706608 0.208 ENST00000256246.2
TEX15
testis expressed 15
chr6_-_152639479 0.190 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_232651312 0.182 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr3_+_43020773 0.179 ENST00000488863.1
FAM198A
family with sequence similarity 198, member A
chr17_-_39156138 0.176 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr4_-_48116540 0.173 ENST00000506073.1
TXK
TXK tyrosine kinase
chr9_+_12693336 0.159 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr3_+_172468505 0.159 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2




epithelial cell transforming sequence 2 oncogene




chr6_-_47445214 0.158 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr2_-_197675000 0.158 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr4_+_128702969 0.146 ENST00000508776.1
ENST00000439123.2
HSPA4L

heat shock 70kDa protein 4-like

chr3_+_172468472 0.146 ENST00000232458.5
ENST00000392692.3
ECT2

epithelial cell transforming sequence 2 oncogene

chr2_-_231860596 0.145 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2






SPATA3 antisense RNA 1 (head to head)






chr13_+_24144796 0.142 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chrX_+_96138907 0.141 ENST00000373040.3
RPA4
replication protein A4, 30kDa
chr4_+_147145709 0.141 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr7_-_115670792 0.140 ENST00000265440.7
ENST00000393485.1
TFEC

transcription factor EC

chr8_+_38662960 0.139 ENST00000524193.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr13_+_24144509 0.131 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr11_+_86085778 0.128 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81



coiled-coil domain containing 81



chr3_+_134514093 0.121 ENST00000398015.3
EPHB1
EPH receptor B1
chr4_+_156775910 0.117 ENST00000506072.1
ENST00000507590.1
TDO2

tryptophan 2,3-dioxygenase

chr11_+_327171 0.114 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12


RP11-326C3.12


chrX_-_48931648 0.110 ENST00000376386.3
ENST00000376390.4
PRAF2

PRA1 domain family, member 2

chrX_+_55478538 0.109 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr10_+_63422695 0.107 ENST00000330194.2
ENST00000389639.3
C10orf107

chromosome 10 open reading frame 107

chr7_-_115670804 0.102 ENST00000320239.7
TFEC
transcription factor EC
chr3_-_183145873 0.099 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF2L2


MCF.2 cell line derived transforming sequence-like 2


chr7_-_107883678 0.095 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr12_+_131438496 0.093 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr9_+_35042205 0.091 ENST00000312292.5
ENST00000378745.3
C9orf131

chromosome 9 open reading frame 131

chr11_-_58378759 0.089 ENST00000601906.1
AP001350.1
Uncharacterized protein
chr12_+_131438443 0.088 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr13_+_78315348 0.087 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr16_-_28937027 0.086 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr2_-_166060382 0.085 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr14_+_38677123 0.082 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr19_+_14693888 0.079 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A


C-type lectin domain family 17, member A


chr13_-_74993252 0.078 ENST00000325811.1
AL355390.1
Uncharacterized protein
chr2_-_10587897 0.078 ENST00000405333.1
ENST00000443218.1
ODC1

ornithine decarboxylase 1

chr15_+_90735145 0.074 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_-_55930443 0.073 ENST00000388975.3
SEPT14
septin 14
chr13_+_78315295 0.070 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr19_+_49199209 0.069 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2


fucosyltransferase 2 (secretor status included)


chr1_-_228613026 0.069 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr1_+_63063152 0.068 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr5_+_102200948 0.067 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM


peptidylglycine alpha-amidating monooxygenase


chr4_+_95128748 0.065 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_-_159237472 0.065 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr20_+_30102231 0.064 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13




histocompatibility (minor) 13




chr6_+_26440700 0.061 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr5_-_130500922 0.061 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1



histidine triad nucleotide binding protein 1



chr5_+_40841276 0.061 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr6_+_26087509 0.057 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr4_-_122085469 0.053 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr14_-_51027838 0.053 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr6_+_161123270 0.053 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr15_-_98417780 0.053 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr14_-_73997901 0.052 ENST00000557603.1
ENST00000556455.1
HEATR4

HEAT repeat containing 4

chr12_+_64798826 0.051 ENST00000540203.1
XPOT
exportin, tRNA
chr6_+_42989344 0.050 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr12_-_10282836 0.049 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A


C-type lectin domain family 7, member A


chrX_-_15332665 0.049 ENST00000537676.1
ENST00000344384.4
ASB11

ankyrin repeat and SOCS box containing 11

chr4_+_15471489 0.048 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A








coiled-coil and C2 domain containing 2A








chr5_+_40841410 0.047 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr4_-_120243545 0.046 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr4_-_19458597 0.044 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr16_-_3350614 0.043 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr7_-_151330218 0.043 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr1_-_178840157 0.042 ENST00000367629.1
ENST00000234816.2
ANGPTL1

angiopoietin-like 1

chr9_-_95166841 0.041 ENST00000262551.4
OGN
osteoglycin
chr5_-_68339648 0.041 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr12_+_59194154 0.040 ENST00000548969.1
RP11-362K2.2
Protein LOC100506869
chr4_+_169418195 0.039 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr2_+_231921574 0.038 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1



proteasome (prosome, macropain) 26S subunit, non-ATPase, 1



chr17_-_4938712 0.037 ENST00000254853.5
ENST00000424747.1
SLC52A1

solute carrier family 52 (riboflavin transporter), member 1

chr6_+_29555683 0.037 ENST00000383640.2
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr3_-_178103144 0.036 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1



RP11-33A14.1



chr14_-_60043524 0.035 ENST00000537690.2
ENST00000281581.4
CCDC175

coiled-coil domain containing 175

chr18_+_61575200 0.035 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr11_-_92931098 0.035 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr5_+_110427983 0.034 ENST00000513710.2
ENST00000505303.1
WDR36

WD repeat domain 36

chr4_+_26324474 0.034 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_152178320 0.033 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr15_-_42500351 0.033 ENST00000348544.4
ENST00000318006.5
VPS39

vacuolar protein sorting 39 homolog (S. cerevisiae)

chr17_-_64225508 0.031 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_139726181 0.031 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr14_-_90798273 0.030 ENST00000357904.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr15_+_51669513 0.027 ENST00000558426.1
GLDN
gliomedin
chr6_-_32095968 0.026 ENST00000375203.3
ENST00000375201.4
ATF6B

activating transcription factor 6 beta

chr4_+_26344754 0.026 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_21377383 0.026 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_-_100872911 0.026 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6


armadillo repeat containing, X-linked 6


chr12_+_75784850 0.025 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2





GLI pathogenesis-related 1 like 2





chr4_+_95128996 0.025 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr11_+_12132117 0.025 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr3_-_191000172 0.025 ENST00000427544.2
UTS2B
urotensin 2B
chr16_+_28565230 0.024 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr14_-_90798418 0.024 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr14_-_23058063 0.023 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1


defender against cell death 1


chr18_-_3845321 0.022 ENST00000539435.1
ENST00000400147.2
DLGAP1

discs, large (Drosophila) homolog-associated protein 1

chr4_+_169418255 0.022 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr1_+_151253991 0.021 ENST00000443959.1
ZNF687
zinc finger protein 687
chr20_-_33735070 0.020 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2


ER degradation enhancer, mannosidase alpha-like 2


chr19_-_51920952 0.020 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10





sialic acid binding Ig-like lectin 10





chr1_-_93257951 0.020 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5


ecotropic viral integration site 5


chr11_-_63376013 0.020 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr2_-_158295915 0.018 ENST00000418920.1
CYTIP
cytohesin 1 interacting protein
chr14_+_45605157 0.018 ENST00000542564.2
FANCM
Fanconi anemia, complementation group M
chr5_-_54988448 0.017 ENST00000503817.1
ENST00000512595.1
SLC38A9

solute carrier family 38, member 9

chr19_-_46234119 0.017 ENST00000317683.3
FBXO46
F-box protein 46
chr1_+_234765057 0.016 ENST00000429269.1
LINC00184
long intergenic non-protein coding RNA 184
chr5_+_96840389 0.016 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr2_+_105050794 0.016 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2


long intergenic non-protein coding RNA 1102


chr19_+_29456034 0.016 ENST00000589921.1
LINC00906
long intergenic non-protein coding RNA 906
chr11_-_62609281 0.016 ENST00000525239.1
ENST00000538098.2
WDR74

WD repeat domain 74

chr10_-_115904361 0.016 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118

chr5_-_54988559 0.015 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr17_-_4710288 0.014 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr12_-_51422017 0.013 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr11_+_28129795 0.013 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr12_+_64798095 0.012 ENST00000332707.5
XPOT
exportin, tRNA
chr10_-_95242044 0.012 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF


myoferlin


chr14_-_74025625 0.012 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEATR4



HEAT repeat containing 4



chr14_+_61449076 0.011 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr1_-_168464875 0.011 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr5_-_173217916 0.010 ENST00000523617.1
CTB-43E15.4
CTB-43E15.4
chr10_-_95241951 0.010 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF


myoferlin


chrX_+_102840408 0.009 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4








transcription elongation factor A (SII)-like 4








chr7_+_13141097 0.009 ENST00000411542.1
AC011288.2
AC011288.2
chr2_-_87248975 0.009 ENST00000409310.2
ENST00000355705.3
PLGLB1

plasminogen-like B1

chr17_-_33390667 0.009 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr11_-_74800799 0.008 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr12_-_110937351 0.006 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr16_+_53133070 0.006 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_+_13141010 0.006 ENST00000443947.1
AC011288.2
AC011288.2
chr1_+_171227069 0.005 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr10_-_27529486 0.004 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr11_-_107729887 0.003 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr3_+_169629354 0.003 ENST00000428432.2
ENST00000335556.3
SAMD7

sterile alpha motif domain containing 7

chr5_-_41794313 0.003 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr6_-_24358264 0.003 ENST00000378454.3
DCDC2
doublecortin domain containing 2
chr1_-_17766198 0.002 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr4_+_25162253 0.002 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr17_-_3496171 0.002 ENST00000399756.4
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr2_-_136633940 0.001 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr1_+_15668240 0.001 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_-_190446759 0.000 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr3_-_141747950 0.000 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr15_+_58702742 0.000 ENST00000356113.6
ENST00000414170.3
LIPC

lipase, hepatic


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 0.5 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631) inactivation of MAPKK activity(GO:0051389)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.3 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.4 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)