Motif ID: IRX6_IRX4

Z-value: 0.177

Transcription factors associated with IRX6_IRX4:

Gene SymbolEntrez IDGene Name
IRX4 ENSG00000113430.5 IRX4
IRX6 ENSG00000159387.7 IRX6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IRX6hg19_v2_chr16_+_55357672_55357672-0.472.1e-01Click!
IRX4hg19_v2_chr5_-_1882858_1883003-0.039.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of IRX6_IRX4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_46716969 0.370 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_143826151 0.117 ENST00000408899.2
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr15_+_54901540 0.077 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr20_+_44330651 0.074 ENST00000305479.2
WFDC13
WAP four-disulfide core domain 13
chr17_+_38673270 0.064 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr3_-_27498235 0.050 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chr16_+_21689835 0.048 ENST00000286149.4
ENST00000388958.3
OTOA

otoancorin

chr21_-_48024986 0.046 ENST00000291700.4
ENST00000367071.4
S100B

S100 calcium binding protein B

chr3_+_111630451 0.046 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr19_-_20048639 0.040 ENST00000595282.1
AC007204.1
Uncharacterized protein
chr5_-_145895753 0.039 ENST00000311104.2
GPR151
G protein-coupled receptor 151
chr11_+_110225855 0.033 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1

RP11-347E10.1

chr16_+_777739 0.032 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr2_+_113670548 0.031 ENST00000263326.3
ENST00000352179.3
ENST00000349806.3
ENST00000353225.3
IL37



interleukin 37



chr1_-_152086556 0.031 ENST00000368804.1
TCHH
trichohyalin
chr9_+_26746951 0.030 ENST00000523363.1
RP11-18A15.1
RP11-18A15.1
chr2_-_231989808 0.029 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr1_-_149859466 0.027 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr5_+_147443534 0.027 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5



serine peptidase inhibitor, Kazal type 5



chr8_-_101724989 0.025 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr16_+_777246 0.024 ENST00000561546.1
ENST00000564545.1
ENST00000389703.3
ENST00000567414.1
ENST00000568141.1
HAGHL




hydroxyacylglutathione hydrolase-like




chr6_+_116691001 0.024 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr1_+_63989004 0.023 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr2_-_238333919 0.023 ENST00000409162.1
AC112721.1
Uncharacterized protein
chr11_-_35547572 0.020 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr1_+_220267429 0.020 ENST00000366922.1
ENST00000302637.5
IARS2

isoleucyl-tRNA synthetase 2, mitochondrial

chr15_-_64665911 0.020 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1


Uncharacterized protein


chrX_-_135962923 0.017 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr16_+_776936 0.017 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
HAGHL



hydroxyacylglutathione hydrolase-like



chr12_-_76462713 0.015 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr4_+_141264597 0.015 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC


short coiled-coil protein


chr14_-_68159152 0.015 ENST00000554035.1
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr14_-_21737551 0.014 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC



















heterogeneous nuclear ribonucleoprotein C (C1/C2)



















chr7_-_55583740 0.014 ENST00000453256.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr14_+_56127960 0.014 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr2_+_58655520 0.013 ENST00000455219.3
ENST00000449448.2
AC007092.1

long intergenic non-protein coding RNA 1122

chr14_+_56127989 0.013 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr16_+_777118 0.013 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr4_-_153303658 0.012 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr10_+_86184676 0.012 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr11_+_61891445 0.011 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr8_+_12803146 0.011 ENST00000447063.2
KIAA1456
KIAA1456
chr1_+_53308398 0.011 ENST00000371528.1
ZYG11A
zyg-11 family member A, cell cycle regulator
chr15_+_66585879 0.011 ENST00000319212.4
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr5_-_177207634 0.011 ENST00000513554.1
ENST00000440605.3
FAM153A

family with sequence similarity 153, member A

chr18_+_616672 0.010 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr17_-_42327236 0.010 ENST00000399246.2
AC003102.1
AC003102.1
chr3_+_68053359 0.010 ENST00000478136.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr4_+_130017268 0.009 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33


chromosome 4 open reading frame 33


chr15_+_66585555 0.009 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3L


DIS3 mitotic control homolog (S. cerevisiae)-like


chr15_-_63448973 0.009 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr17_-_6524159 0.009 ENST00000589033.1
KIAA0753
KIAA0753
chr3_+_186158169 0.008 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1

RP11-78H24.1

chr8_+_67976593 0.008 ENST00000262210.5
ENST00000412460.1
CSPP1

centrosome and spindle pole associated protein 1

chr1_-_3566627 0.008 ENST00000419924.2
ENST00000270708.7
WRAP73

WD repeat containing, antisense to TP73

chr19_-_48059113 0.008 ENST00000391901.3
ENST00000314121.4
ENST00000448976.1
ZNF541


zinc finger protein 541


chr7_+_23210760 0.007 ENST00000366347.4
AC005082.1
Uncharacterized protein
chr10_+_118349920 0.007 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr6_+_149887377 0.007 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr10_-_115904361 0.007 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118

chr12_-_10282742 0.006 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A


C-type lectin domain family 7, member A


chr1_-_3566590 0.006 ENST00000424367.1
ENST00000378322.3
WRAP73

WD repeat containing, antisense to TP73

chr1_+_212475148 0.006 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr5_+_175490540 0.006 ENST00000515817.1
FAM153B
family with sequence similarity 153, member B
chr7_+_6121296 0.005 ENST00000428901.1
AC004895.4
AC004895.4
chr19_+_50691437 0.005 ENST00000598205.1
MYH14
myosin, heavy chain 14, non-muscle
chr1_-_89641680 0.005 ENST00000294671.2
GBP7
guanylate binding protein 7
chr4_-_143481822 0.005 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_104119528 0.004 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE


centromere protein E, 312kDa


chr2_+_58655461 0.004 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr4_-_104119488 0.004 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chr21_-_26890650 0.004 ENST00000419694.1
AP000221.1
AP000221.1
chr17_-_47723943 0.004 ENST00000510476.1
ENST00000503676.1
SPOP

speckle-type POZ protein

chr18_-_46784778 0.003 ENST00000582399.1
DYM
dymeclin
chr12_+_53848549 0.003 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2


poly(rC) binding protein 2


chr2_-_183106641 0.003 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_+_71458012 0.003 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chrX_-_19988382 0.003 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr21_-_34186006 0.002 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr4_+_71457970 0.002 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr1_-_110284384 0.002 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr18_-_28622774 0.002 ENST00000434452.1
DSC3
desmocollin 3
chr12_-_124118151 0.002 ENST00000534960.1
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr12_-_88423164 0.002 ENST00000298699.2
ENST00000550553.1
C12orf50

chromosome 12 open reading frame 50

chr4_+_113558612 0.002 ENST00000505034.1
ENST00000324052.6
LARP7

La ribonucleoprotein domain family, member 7

chr4_-_177190364 0.001 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr6_-_117747015 0.001 ENST00000368508.3
ENST00000368507.3
ROS1

c-ros oncogene 1 , receptor tyrosine kinase


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)