Motif ID: IRF7

Z-value: 0.650


Transcription factors associated with IRF7:

Gene SymbolEntrez IDGene Name
IRF7 ENSG00000185507.15 IRF7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_6157280.791.2e-02Click!


Activity profile for motif IRF7.

activity profile for motif IRF7


Sorted Z-values histogram for motif IRF7

Sorted Z-values for motif IRF7



Network of associatons between targets according to the STRING database.



First level regulatory network of IRF7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_17516449 1.196 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr10_+_91152303 1.096 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr11_+_34643600 1.078 ENST00000530286.1
ENST00000533754.1
EHF

ets homologous factor

chr6_-_46889694 0.929 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116


G protein-coupled receptor 116


chr6_+_116782527 0.926 ENST00000368606.3
ENST00000368605.1
FAM26F

family with sequence similarity 26, member F

chr8_+_39770803 0.899 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr12_-_10007448 0.863 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr11_+_63304273 0.765 ENST00000439013.2
ENST00000255688.3
RARRES3

retinoic acid receptor responder (tazarotene induced) 3

chr2_+_7017796 0.691 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr9_-_119162885 0.686 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr10_+_91061712 0.675 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr3_+_187086120 0.643 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr11_+_34663913 0.602 ENST00000532302.1
EHF
ets homologous factor
chr16_+_10972818 0.551 ENST00000576601.1
CIITA
class II, major histocompatibility complex, transactivator
chr4_-_25865159 0.550 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr1_+_948803 0.544 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr18_+_61554932 0.530 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr20_+_10199468 0.519 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr14_-_54420133 0.514 ENST00000559501.1
ENST00000558984.1
BMP4

bone morphogenetic protein 4

chr12_-_10022735 0.501 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr1_-_111746966 0.496 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr11_+_34664014 0.492 ENST00000527935.1
EHF
ets homologous factor
chr11_-_104916034 0.491 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16


caspase recruitment domain family, member 16


chr1_+_110453514 0.487 ENST00000369802.3
ENST00000420111.2
CSF1

colony stimulating factor 1 (macrophage)

chr12_+_113416191 0.485 ENST00000342315.4
ENST00000392583.2
OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

chr1_+_110453608 0.482 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr16_+_19179549 0.468 ENST00000355377.2
ENST00000568115.1
SYT17

synaptotagmin XVII

chr1_+_110453462 0.464 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr1_+_110453109 0.461 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr1_+_110453203 0.456 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr10_-_92681033 0.446 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr6_+_122931366 0.440 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB


protein kinase (cAMP-dependent, catalytic) inhibitor beta


chr5_+_32710736 0.435 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr10_+_91092241 0.431 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_-_145277640 0.426 ENST00000539609.3
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_228028829 0.409 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr7_-_122526499 0.408 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr11_+_34654011 0.407 ENST00000531794.1
EHF
ets homologous factor
chr22_+_36649170 0.396 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1





apolipoprotein L, 1





chr2_+_33701286 0.393 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_36245561 0.383 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_65215604 0.382 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_-_49318715 0.381 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr3_+_187957646 0.379 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_113416340 0.375 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr2_-_145277569 0.373 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr11_-_104972158 0.361 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr7_-_122526799 0.359 ENST00000334010.7
ENST00000313070.7
CADPS2

Ca++-dependent secretion activator 2

chr3_-_171489085 0.354 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr7_+_142498725 0.353 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr12_+_113416265 0.350 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr6_-_26056695 0.350 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr1_+_82266053 0.346 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr20_+_9146969 0.340 ENST00000416836.1
PLCB4
phospholipase C, beta 4
chr1_+_104104379 0.334 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr2_+_210444142 0.333 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr5_+_140734570 0.330 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr17_-_4643161 0.327 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr2_+_210444748 0.325 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr2_+_226273597 0.316 ENST00000409269.2
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr6_-_137365402 0.313 ENST00000541547.1
IL20RA
interleukin 20 receptor, alpha
chr1_-_169680745 0.310 ENST00000236147.4
SELL
selectin L
chr8_-_82608409 0.308 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr8_+_17434689 0.307 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr6_-_137366096 0.305 ENST00000316649.5
ENST00000367746.3
IL20RA

interleukin 20 receptor, alpha

chr11_-_104905840 0.294 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr22_+_36649056 0.294 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
APOL1



apolipoprotein L, 1



chr19_+_17516624 0.290 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9


CTD-2521M24.9


chr7_-_122526411 0.289 ENST00000449022.2
CADPS2
Ca++-dependent secretion activator 2
chr10_+_88780049 0.286 ENST00000343959.4
FAM25A
family with sequence similarity 25, member A
chr3_+_185046676 0.284 ENST00000428617.1
ENST00000443863.1
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr10_-_61495760 0.279 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr10_+_24498060 0.278 ENST00000376454.3
ENST00000376452.3
KIAA1217

KIAA1217

chr2_+_102721023 0.278 ENST00000409589.1
ENST00000409329.1
IL1R1

interleukin 1 receptor, type I

chr12_-_49319265 0.272 ENST00000552878.1
ENST00000453172.2
FKBP11

FK506 binding protein 11, 19 kDa

chr4_-_139163491 0.271 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr4_+_41614720 0.270 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr10_+_91087651 0.270 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr12_+_113344582 0.268 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr9_-_114521783 0.268 ENST00000394779.3
ENST00000394777.4
C9orf84

chromosome 9 open reading frame 84

chr2_+_210443993 0.267 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr12_-_26278030 0.265 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr4_+_41614909 0.264 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr10_+_24497704 0.254 ENST00000376456.4
ENST00000458595.1
KIAA1217

KIAA1217

chr4_+_147145709 0.252 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr6_+_123038689 0.250 ENST00000354275.2
ENST00000368446.1
PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr18_+_32173276 0.249 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr7_-_92777606 0.244 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chrX_-_13835461 0.244 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr4_-_73434498 0.242 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr19_+_17516494 0.240 ENST00000534306.1
CTD-2521M24.9
CTD-2521M24.9
chr4_-_76957214 0.238 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr2_+_207308539 0.235 ENST00000374416.1
ENST00000374415.3
ADAM23

ADAM metallopeptidase domain 23

chr18_+_19750894 0.235 ENST00000581694.1
GATA6
GATA binding protein 6
chr3_+_188817891 0.234 ENST00000412373.1
TPRG1
tumor protein p63 regulated 1
chr4_-_40517984 0.233 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr1_+_79115503 0.233 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr16_-_67597789 0.233 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr2_+_85811525 0.232 ENST00000306384.4
VAMP5
vesicle-associated membrane protein 5
chr22_-_36556821 0.227 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3


apolipoprotein L, 3


chr2_-_151344172 0.226 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr2_-_7005785 0.222 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2


cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial


chr6_-_137366163 0.218 ENST00000367748.1
IL20RA
interleukin 20 receptor, alpha
chr3_+_187871659 0.216 ENST00000416784.1
ENST00000430340.1
ENST00000414139.1
ENST00000454789.1
LPP



LIM domain containing preferred translocation partner in lipoma



chr2_-_45165994 0.216 ENST00000444871.2
RP11-89K21.1
RP11-89K21.1
chr17_-_29624343 0.214 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr6_-_94129244 0.211 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr8_-_18942240 0.211 ENST00000521475.1
PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_68788594 0.210 ENST00000396442.2
ENST00000380766.2
OCLN

occludin

chrX_+_103031421 0.209 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1


proteolipid protein 1


chr1_+_12227035 0.208 ENST00000376259.3
ENST00000536782.1
TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

chr7_-_47621229 0.207 ENST00000434451.1
TNS3
tensin 3
chr4_-_169239921 0.204 ENST00000514995.1
ENST00000393743.3
DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

chr17_-_33864772 0.203 ENST00000361112.4
SLFN12L
schlafen family member 12-like
chr2_+_210444298 0.202 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr1_+_79086088 0.202 ENST00000370751.5
ENST00000342282.3
IFI44L

interferon-induced protein 44-like

chr17_-_40264692 0.200 ENST00000591220.1
ENST00000251642.3
DHX58

DEXH (Asp-Glu-X-His) box polypeptide 58

chr5_+_140749803 0.199 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr3_+_46449049 0.197 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2


chemokine (C-C motif) receptor-like 2


chr12_+_40618764 0.197 ENST00000343742.2
LRRK2
leucine-rich repeat kinase 2
chr1_+_43613612 0.196 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr4_+_75174180 0.195 ENST00000413830.1
EPGN
epithelial mitogen
chr11_+_111789580 0.193 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr17_-_4642429 0.188 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr15_+_59908633 0.187 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_-_231084659 0.184 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110



SP110 nuclear body protein



chr4_-_76944621 0.183 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr17_-_39156138 0.183 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr1_+_167599532 0.183 ENST00000537350.1
RCSD1
RCSD domain containing 1
chr8_-_110615669 0.183 ENST00000533394.1
SYBU
syntabulin (syntaxin-interacting)
chr11_-_60720002 0.182 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr3_+_46448648 0.178 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr11_-_112034780 0.177 ENST00000524595.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr2_-_163175133 0.176 ENST00000421365.2
ENST00000263642.2
IFIH1

interferon induced with helicase C domain 1

chr1_-_12677714 0.176 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr17_-_40264321 0.175 ENST00000430773.1
ENST00000413196.2
DHX58

DEXH (Asp-Glu-X-His) box polypeptide 58

chr18_+_32398326 0.173 ENST00000269192.7
ENST00000591182.1
ENST00000597674.1
ENST00000556414.3
DTNA



dystrobrevin, alpha



chr22_-_36635225 0.172 ENST00000529194.1
APOL2
apolipoprotein L, 2
chr6_-_56492816 0.170 ENST00000522360.1
DST
dystonin
chrX_+_10126488 0.170 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4


chloride channel, voltage-sensitive 4


chr6_-_19804877 0.169 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr1_-_44497024 0.167 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr7_-_122339162 0.167 ENST00000340112.2
RNF133
ring finger protein 133
chrX_+_9880590 0.164 ENST00000452575.1
SHROOM2
shroom family member 2
chr12_+_32654965 0.163 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_-_44497118 0.162 ENST00000537678.1
ENST00000466926.1
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr2_-_175629164 0.161 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1


cholinergic receptor, nicotinic, alpha 1 (muscle)


chr22_+_18632666 0.161 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr22_-_36635563 0.160 ENST00000451256.2
APOL2
apolipoprotein L, 2
chr11_-_7961141 0.159 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr5_+_140593509 0.159 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr16_-_54972581 0.155 ENST00000559802.1
ENST00000558156.1
CTD-3032H12.1

CTD-3032H12.1

chr11_+_77774897 0.155 ENST00000281030.2
THRSP
thyroid hormone responsive
chr7_-_130597935 0.153 ENST00000447307.1
ENST00000418546.1
MIR29B1

microRNA 29a

chr7_-_14029515 0.152 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chrX_+_22050546 0.151 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr2_-_158345341 0.149 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr12_+_10365082 0.148 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_+_169658928 0.146 ENST00000317647.7
ENST00000445023.2
NOSTRIN

nitric oxide synthase trafficking

chr1_-_183560011 0.146 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr12_+_113344755 0.146 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chrX_+_103031758 0.146 ENST00000303958.2
ENST00000361621.2
PLP1

proteolipid protein 1

chr14_+_76044934 0.143 ENST00000238667.4
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr1_-_9262678 0.143 ENST00000437157.2
RP3-510D11.1
RP3-510D11.1
chr8_+_26150628 0.142 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr22_-_36635684 0.142 ENST00000358502.5
APOL2
apolipoprotein L, 2
chr2_-_170430277 0.141 ENST00000438035.1
ENST00000453929.2
FASTKD1

FAST kinase domains 1

chr6_+_27925019 0.141 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr15_+_45021183 0.140 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr1_+_159796589 0.137 ENST00000368104.4
SLAMF8
SLAM family member 8
chr9_-_39239171 0.137 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr18_+_3451646 0.136 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1


TGFB-induced factor homeobox 1


chr5_-_95158644 0.135 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr14_+_32546145 0.135 ENST00000556611.1
ENST00000539826.2
ARHGAP5

Rho GTPase activating protein 5

chr20_-_25038804 0.135 ENST00000323482.4
ACSS1
acyl-CoA synthetase short-chain family member 1
chr17_+_36584662 0.134 ENST00000431231.2
ENST00000437668.3
ARHGAP23

Rho GTPase activating protein 23

chr8_-_23540402 0.133 ENST00000523261.1
ENST00000380871.4
NKX3-1

NK3 homeobox 1

chrX_+_56259316 0.132 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr6_+_46661575 0.132 ENST00000450697.1
TDRD6
tudor domain containing 6
chr9_+_70971815 0.131 ENST00000396392.1
ENST00000396396.1
PGM5

phosphoglucomutase 5

chr22_-_36635598 0.130 ENST00000454728.1
APOL2
apolipoprotein L, 2
chr2_-_231084820 0.130 ENST00000258382.5
ENST00000338556.3
SP110

SP110 nuclear body protein

chr12_-_7245125 0.130 ENST00000542285.1
ENST00000540610.1
C1R

complement component 1, r subcomponent

chr7_-_130598059 0.129 ENST00000432045.2
MIR29B1
microRNA 29a
chr6_+_26440700 0.128 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr12_-_92536433 0.128 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr2_+_162949939 0.127 ENST00000432251.1
AC008063.3
AC008063.3
chr2_+_231090471 0.126 ENST00000373645.3
SP140
SP140 nuclear body protein
chr3_+_112051994 0.126 ENST00000473539.1
ENST00000315711.8
ENST00000383681.3
CD200


CD200 molecule


chr2_-_175629135 0.126 ENST00000409542.1
ENST00000409219.1
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr17_-_38978847 0.125 ENST00000269576.5
KRT10
keratin 10
chr12_-_7245080 0.125 ENST00000541042.1
ENST00000540242.1
C1R

complement component 1, r subcomponent

chr1_+_112016414 0.125 ENST00000343534.5
ENST00000369718.3
C1orf162

chromosome 1 open reading frame 162

chr3_-_179169181 0.125 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr2_-_170430366 0.125 ENST00000453153.2
ENST00000445210.1
FASTKD1

FAST kinase domains 1

chr4_-_38806404 0.125 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr10_-_21806759 0.124 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr15_+_26360970 0.124 ENST00000556159.1
ENST00000557523.1
LINC00929

long intergenic non-protein coding RNA 929

chr2_-_55237484 0.124 ENST00000394609.2
RTN4
reticulon 4
chr1_-_11741155 0.123 ENST00000445656.1
ENST00000376669.5
ENST00000456915.1
ENST00000376692.4
MAD2L2



MAD2 mitotic arrest deficient-like 2 (yeast)




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.4 1.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.3 0.9 GO:0036269 swimming behavior(GO:0036269)
0.3 1.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.7 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 1.2 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 1.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 1.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.8 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.2 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.1 GO:0008037 cell recognition(GO:0008037)
0.1 0.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.2 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.2 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.2 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.5 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.1 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0 0.2 GO:0051133 regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.6 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.3 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:1990641 negative regulation of T cell cytokine production(GO:0002725) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.9 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.0 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.0 0.0 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.7 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.0 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.0 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.3 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.0 GO:0019401 alditol biosynthetic process(GO:0019401)
0.0 0.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.7 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 0.9 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.2 1.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.9 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.4 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.0 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME_SIGNALING_BY_ILS Genes involved in Signaling by Interleukins
0.0 0.1 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane