Motif ID: IRF2_STAT2_IRF8_IRF1
Z-value: 5.213
Transcription factors associated with IRF2_STAT2_IRF8_IRF1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| IRF1 | ENSG00000125347.9 | IRF1 |
| IRF2 | ENSG00000168310.6 | IRF2 |
| IRF8 | ENSG00000140968.6 | IRF8 |
| STAT2 | ENSG00000170581.9 | STAT2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| STAT2 | hg19_v2_chr12_-_56753858_56753930 | 0.99 | 7.8e-08 | Click! |
| IRF1 | hg19_v2_chr5_-_131826457_131826514 | 0.98 | 5.6e-06 | Click! |
| IRF2 | hg19_v2_chr4_-_185395191_185395340 | -0.52 | 1.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.7 | 23.2 | GO:0002731 | negative regulation of dendritic cell cytokine production(GO:0002731) |
| 7.6 | 37.9 | GO:1902228 | mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 5.4 | 32.4 | GO:0034165 | positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) |
| 4.7 | 14.2 | GO:0036269 | swimming behavior(GO:0036269) |
| 3.5 | 14.0 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 3.4 | 20.4 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 2.8 | 8.3 | GO:0002586 | regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) |
| 2.6 | 10.2 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 2.4 | 9.6 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 2.3 | 25.6 | GO:0018377 | protein myristoylation(GO:0018377) |
| 2.1 | 27.5 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 2.0 | 20.2 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 2.0 | 18.1 | GO:1902748 | mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 2.0 | 8.0 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 2.0 | 6.0 | GO:0050823 | peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823) |
| 1.8 | 1.8 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 1.7 | 5.1 | GO:2001190 | natural killer cell tolerance induction(GO:0002519) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 1.6 | 18.7 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 1.4 | 5.5 | GO:0034124 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) |
| 1.2 | 4.8 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 1.2 | 4.6 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 1.1 | 4.3 | GO:1905123 | regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123) |
| 1.1 | 3.2 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 1.0 | 7.8 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.0 | 2.9 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 0.9 | 4.4 | GO:0032912 | negative regulation of transforming growth factor beta2 production(GO:0032912) |
| 0.8 | 2.5 | GO:1902823 | negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217) |
| 0.8 | 2.5 | GO:0043012 | regulation of fusion of sperm to egg plasma membrane(GO:0043012) |
| 0.8 | 4.0 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 0.8 | 7.7 | GO:0045348 | positive regulation of MHC class II biosynthetic process(GO:0045348) |
| 0.7 | 2.2 | GO:1990641 | response to iron ion starvation(GO:1990641) |
| 0.7 | 8.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.7 | 5.8 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.7 | 4.2 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.7 | 2.0 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.7 | 1.3 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.7 | 4.0 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 0.7 | 3.3 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.7 | 4.6 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.7 | 8.5 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
| 0.7 | 2.6 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.6 | 3.1 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.6 | 13.3 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.6 | 1.8 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.6 | 7.6 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.6 | 0.6 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 0.5 | 4.2 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.5 | 0.5 | GO:0034759 | regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) |
| 0.5 | 2.5 | GO:0036343 | psychomotor behavior(GO:0036343) |
| 0.5 | 1.5 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.5 | 7.1 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.4 | 3.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.4 | 3.0 | GO:2000111 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.4 | 1.3 | GO:1905246 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.4 | 3.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.4 | 1.7 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.4 | 2.5 | GO:2000834 | androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) |
| 0.4 | 2.5 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.4 | 2.4 | GO:2000329 | negative regulation of T-helper 17 cell lineage commitment(GO:2000329) |
| 0.4 | 2.3 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.4 | 1.1 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 0.4 | 1.1 | GO:0060981 | cell migration involved in coronary angiogenesis(GO:0060981) |
| 0.4 | 12.4 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.4 | 1.4 | GO:1990418 | response to insulin-like growth factor stimulus(GO:1990418) |
| 0.4 | 8.5 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.3 | 2.3 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 0.3 | 2.0 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.3 | 1.0 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
| 0.3 | 2.9 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.3 | 1.3 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.3 | 1.9 | GO:0019427 | acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542) |
| 0.3 | 1.8 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.3 | 3.3 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.3 | 0.6 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.3 | 1.7 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.3 | 9.3 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.3 | 0.8 | GO:0036482 | neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) |
| 0.3 | 1.1 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.3 | 2.7 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 0.3 | 2.9 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.3 | 3.1 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.3 | 0.8 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.3 | 3.8 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.2 | 0.7 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.2 | 6.1 | GO:0045838 | positive regulation of membrane potential(GO:0045838) |
| 0.2 | 1.4 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.2 | 10.3 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.2 | 1.2 | GO:0039506 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 0.2 | 0.2 | GO:0050787 | detoxification of mercury ion(GO:0050787) |
| 0.2 | 5.2 | GO:0097296 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
| 0.2 | 1.4 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.2 | 1.4 | GO:0030421 | defecation(GO:0030421) |
| 0.2 | 1.1 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.2 | 0.9 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.2 | 0.9 | GO:1990535 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535) |
| 0.2 | 2.2 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
| 0.2 | 0.6 | GO:0021538 | epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866) |
| 0.2 | 0.2 | GO:0046668 | retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668) |
| 0.2 | 2.7 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 7.0 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.2 | 0.9 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.2 | 4.1 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
| 0.2 | 3.1 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.2 | 1.9 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.2 | 1.3 | GO:1902044 | Fas signaling pathway(GO:0036337) regulation of Fas signaling pathway(GO:1902044) |
| 0.2 | 3.1 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.2 | 1.5 | GO:0032700 | negative regulation of interleukin-17 production(GO:0032700) |
| 0.2 | 0.6 | GO:0033685 | negative regulation of luteinizing hormone secretion(GO:0033685) |
| 0.2 | 4.3 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
| 0.2 | 0.5 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.2 | 8.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.2 | 0.3 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
| 0.2 | 3.9 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.2 | 0.5 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.2 | 0.5 | GO:1904604 | regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204) |
| 0.2 | 2.6 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 0.2 | 2.9 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 0.9 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 1.2 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.1 | 1.0 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.1 | 0.4 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 1.3 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.1 | 0.3 | GO:0060300 | regulation of cytokine activity(GO:0060300) |
| 0.1 | 1.6 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 0.3 | GO:0060809 | mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) |
| 0.1 | 0.8 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.1 | 3.0 | GO:0071474 | cellular hyperosmotic response(GO:0071474) |
| 0.1 | 0.9 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 1.3 | GO:0009134 | nucleoside diphosphate catabolic process(GO:0009134) |
| 0.1 | 2.5 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 0.6 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.1 | 3.8 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.1 | 0.4 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.1 | 3.4 | GO:0002360 | T cell lineage commitment(GO:0002360) |
| 0.1 | 15.0 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.1 | 0.2 | GO:0045994 | positive regulation of translational initiation by iron(GO:0045994) |
| 0.1 | 0.2 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 0.1 | 0.7 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.1 | 1.6 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
| 0.1 | 2.2 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 0.6 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.1 | 9.3 | GO:0060135 | maternal process involved in female pregnancy(GO:0060135) |
| 0.1 | 0.8 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 0.8 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 2.1 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.1 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.8 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 0.8 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.1 | 0.1 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) |
| 0.1 | 0.7 | GO:0060486 | Clara cell differentiation(GO:0060486) |
| 0.1 | 1.1 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.1 | 0.4 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.1 | 0.6 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.3 | GO:0019883 | antigen processing and presentation of endogenous antigen(GO:0019883) |
| 0.1 | 1.7 | GO:0046520 | sphingoid biosynthetic process(GO:0046520) |
| 0.1 | 0.4 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.1 | 2.4 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.1 | 0.1 | GO:0002856 | negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) |
| 0.1 | 0.6 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.3 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
| 0.1 | 0.2 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.1 | 0.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 0.7 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 0.2 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.1 | 5.9 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.1 | 0.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.6 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 0.2 | GO:0090425 | hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.1 | 3.8 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.1 | 1.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.3 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.1 | 0.4 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.1 | 1.2 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.1 | 0.4 | GO:0042335 | cuticle development(GO:0042335) |
| 0.1 | 0.2 | GO:0046022 | positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.1 | 1.7 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 0.4 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 0.1 | 2.3 | GO:0045124 | regulation of bone resorption(GO:0045124) |
| 0.1 | 0.6 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.1 | 0.5 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.1 | 1.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 5.1 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.1 | 0.6 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.1 | 0.2 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.2 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.1 | 0.3 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.1 | 0.2 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.1 | 0.2 | GO:0033037 | polysaccharide localization(GO:0033037) |
| 0.1 | 0.4 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.2 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.1 | 0.3 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.1 | 0.5 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.1 | 0.3 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.1 | 1.7 | GO:0035994 | response to muscle stretch(GO:0035994) |
| 0.1 | 0.3 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.1 | 0.7 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 0.9 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.8 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.4 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.0 | 0.1 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.0 | 0.1 | GO:0048682 | axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 0.0 | 2.3 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.0 | 0.3 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.0 | 0.1 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.0 | 0.1 | GO:0016553 | base conversion or substitution editing(GO:0016553) |
| 0.0 | 2.1 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.1 | GO:0008052 | sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193) |
| 0.0 | 0.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.3 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.0 | 1.2 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.0 | 0.4 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.0 | 0.3 | GO:0070541 | response to platinum ion(GO:0070541) |
| 0.0 | 0.5 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.0 | 0.1 | GO:0015993 | L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.0 | 0.8 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.2 | GO:0035669 | TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669) |
| 0.0 | 0.2 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.0 | 1.0 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.3 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.0 | 0.2 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 0.0 | 0.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.6 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.0 | 0.2 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.0 | 1.4 | GO:0040036 | regulation of fibroblast growth factor receptor signaling pathway(GO:0040036) |
| 0.0 | 3.1 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.0 | 0.2 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.9 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 2.2 | GO:0002756 | MyD88-independent toll-like receptor signaling pathway(GO:0002756) |
| 0.0 | 0.6 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.3 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.3 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.0 | 0.7 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 0.8 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.0 | 0.2 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.0 | 0.1 | GO:0034130 | toll-like receptor 1 signaling pathway(GO:0034130) |
| 0.0 | 0.4 | GO:0009607 | response to biotic stimulus(GO:0009607) |
| 0.0 | 1.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.6 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.0 | 2.0 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.3 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 0.9 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.0 | 1.9 | GO:0006536 | glutamate metabolic process(GO:0006536) |
| 0.0 | 7.2 | GO:0006818 | hydrogen transport(GO:0006818) |
| 0.0 | 1.2 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 1.0 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.1 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
| 0.0 | 0.4 | GO:0021794 | thalamus development(GO:0021794) |
| 0.0 | 0.1 | GO:0070227 | lymphocyte apoptotic process(GO:0070227) |
| 0.0 | 0.3 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.4 | GO:0008090 | retrograde axonal transport(GO:0008090) positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 0.1 | GO:1903598 | positive regulation of gap junction assembly(GO:1903598) |
| 0.0 | 1.1 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
| 0.0 | 0.4 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.0 | 0.2 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.0 | 0.1 | GO:0009443 | pyridoxal 5'-phosphate salvage(GO:0009443) |
| 0.0 | 0.1 | GO:1990523 | bone regeneration(GO:1990523) |
| 0.0 | 0.4 | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103) |
| 0.0 | 2.8 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.6 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 0.8 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 1.4 | GO:0045840 | positive regulation of mitotic nuclear division(GO:0045840) |
| 0.0 | 0.2 | GO:1901164 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164) |
| 0.0 | 1.0 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.0 | 0.8 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
| 0.0 | 0.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.0 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.0 | 0.1 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.0 | 0.1 | GO:0034486 | vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.0 | 0.1 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.0 | 0.1 | GO:0033385 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.0 | 0.3 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.0 | 7.5 | GO:0050673 | epithelial cell proliferation(GO:0050673) |
| 0.0 | 0.2 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.0 | 0.2 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.2 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.0 | 0.6 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.2 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 0.2 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.9 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 0.1 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.0 | 0.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 2.0 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 1.0 | GO:0003281 | ventricular septum development(GO:0003281) |
| 0.0 | 0.3 | GO:1900116 | extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 0.0 | 0.9 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.1 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 0.4 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.0 | 0.1 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.0 | 0.1 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.1 | GO:0021678 | third ventricle development(GO:0021678) |
| 0.0 | 0.2 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.4 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.0 | 0.5 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.0 | 0.1 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.0 | 0.6 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.2 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.0 | 0.1 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.0 | 1.5 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.7 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 0.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 1.4 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.4 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 0.0 | 0.1 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.0 | 0.2 | GO:0071356 | cellular response to tumor necrosis factor(GO:0071356) |
| 0.0 | 0.1 | GO:0016267 | O-glycan processing, core 1(GO:0016267) |
| 0.0 | 0.4 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.0 | 0.2 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.0 | 0.2 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.0 | 0.1 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.1 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.0 | 0.1 | GO:0001712 | ectodermal cell fate commitment(GO:0001712) |
| 0.0 | 0.2 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 0.1 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.0 | 0.2 | GO:0006828 | manganese ion transport(GO:0006828) |
| 0.0 | 0.1 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 0.6 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.3 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.0 | 1.7 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.1 | GO:0098907 | protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.0 | 0.1 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.0 | 0.0 | GO:0048627 | myoblast development(GO:0048627) |
| 0.0 | 0.1 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.0 | 0.3 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.1 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.0 | 0.1 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.0 | 0.4 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.9 | GO:0009311 | oligosaccharide metabolic process(GO:0009311) |
| 0.0 | 0.1 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 1.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.1 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 0.3 | GO:0006457 | protein folding(GO:0006457) |
| 0.0 | 0.2 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.0 | 0.2 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.4 | 37.9 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 2.7 | 16.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 2.4 | 16.6 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 1.1 | 5.5 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.7 | 1.5 | GO:0031906 | late endosome lumen(GO:0031906) |
| 0.7 | 5.6 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.7 | 4.6 | GO:0042825 | TAP complex(GO:0042825) |
| 0.6 | 2.5 | GO:0044753 | amphisome(GO:0044753) |
| 0.5 | 2.1 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.5 | 14.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.5 | 5.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.5 | 2.7 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.4 | 1.2 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.4 | 1.1 | GO:0020005 | symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) |
| 0.3 | 2.2 | GO:1990357 | terminal web(GO:1990357) |
| 0.3 | 21.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.3 | 2.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.2 | 5.7 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.2 | 2.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.2 | 1.6 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.2 | 27.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 2.6 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.2 | 1.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.2 | 5.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 0.9 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.2 | 1.0 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.2 | 0.5 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.1 | 0.7 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 1.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.1 | 0.6 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 1.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 1.8 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 1.5 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 4.4 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 0.9 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.1 | 17.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 8.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 12.7 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.1 | 0.6 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 0.8 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.1 | 0.8 | GO:0097413 | Lewy body(GO:0097413) |
| 0.1 | 0.2 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.1 | 2.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 1.3 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.3 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.1 | 0.7 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.1 | 9.5 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.9 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.8 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.1 | 1.6 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.1 | 1.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 1.0 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 13.4 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.1 | 0.3 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 10.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 0.8 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.2 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.1 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.0 | 2.3 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 0.2 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.0 | 3.4 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 8.0 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.8 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.1 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.0 | 0.8 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 1.1 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.4 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 0.4 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.0 | 3.9 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.1 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.0 | 2.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 3.8 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 2.1 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 6.0 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 10.6 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.6 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 1.6 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.1 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.0 | 0.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.3 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 1.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 1.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.6 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.3 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 1.0 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 4.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 0.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 1.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 24.0 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 0.1 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.0 | 0.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 1.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 14.3 | GO:0005794 | Golgi apparatus(GO:0005794) |
| 0.0 | 1.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 2.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.6 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.0 | 0.1 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 1.8 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.1 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 1.3 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 2.0 | GO:0031674 | I band(GO:0031674) |
| 0.0 | 0.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.6 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 18.8 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 0.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 1.6 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 2.4 | GO:0098794 | postsynapse(GO:0098794) |
| 0.0 | 0.3 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 0.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.2 | GO:0036379 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.0 | 0.3 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 4.0 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.3 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.1 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.9 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 37.3 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 4.7 | 14.2 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 2.8 | 8.3 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 2.4 | 9.6 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 2.3 | 27.7 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 2.1 | 12.6 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 1.9 | 5.6 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 1.2 | 9.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 1.2 | 7.1 | GO:0022897 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 1.2 | 4.6 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) |
| 1.2 | 4.6 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 1.0 | 8.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 1.0 | 6.1 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 1.0 | 8.1 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 1.0 | 4.8 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.9 | 12.1 | GO:0031386 | protein tag(GO:0031386) |
| 0.9 | 23.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.8 | 8.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.8 | 3.2 | GO:0005019 | platelet-derived growth factor beta-receptor activity(GO:0005019) |
| 0.8 | 9.8 | GO:0089720 | caspase binding(GO:0089720) |
| 0.7 | 2.1 | GO:1904713 | beta-catenin destruction complex binding(GO:1904713) |
| 0.6 | 5.1 | GO:0005534 | galactose binding(GO:0005534) |
| 0.6 | 4.2 | GO:0018636 | phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) |
| 0.6 | 16.1 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.6 | 4.0 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.6 | 1.7 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.5 | 2.7 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.5 | 3.1 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.5 | 32.1 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.5 | 4.6 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.4 | 4.8 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.4 | 6.1 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.4 | 9.8 | GO:0008035 | high-density lipoprotein particle binding(GO:0008035) |
| 0.4 | 3.8 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.4 | 2.5 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.4 | 2.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.4 | 1.1 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.4 | 2.5 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.3 | 9.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.3 | 21.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.3 | 9.1 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.3 | 2.6 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.3 | 2.6 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.3 | 1.1 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.3 | 9.7 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.3 | 1.9 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 0.3 | 0.8 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.3 | 0.5 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.2 | 2.2 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 0.2 | 4.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.2 | 30.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.2 | 1.9 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.2 | 1.6 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.2 | 1.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.2 | 7.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.2 | 3.9 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.2 | 1.0 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.2 | 1.1 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.2 | 5.7 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 0.9 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.2 | 5.9 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.2 | 1.4 | GO:0019864 | IgG binding(GO:0019864) |
| 0.2 | 1.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.2 | 5.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 1.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.2 | 3.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 0.5 | GO:1904599 | advanced glycation end-product binding(GO:1904599) |
| 0.1 | 1.3 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 0.9 | GO:1903135 | cupric ion binding(GO:1903135) |
| 0.1 | 1.1 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.1 | 6.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 3.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 3.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.6 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.1 | 6.7 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 0.5 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.1 | 0.4 | GO:0051499 | D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500) |
| 0.1 | 0.4 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.1 | 0.8 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.1 | 15.5 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.1 | 0.2 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.1 | 0.3 | GO:0042007 | interleukin-18 binding(GO:0042007) |
| 0.1 | 0.7 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 0.2 | GO:0046978 | TAP binding(GO:0046977) TAP1 binding(GO:0046978) |
| 0.1 | 1.6 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 0.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 2.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 0.6 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.1 | 1.4 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 5.2 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 1.1 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 1.0 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.1 | 0.9 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.2 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.1 | 0.2 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.1 | 1.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 0.2 | GO:0030626 | U12 snRNA binding(GO:0030626) |
| 0.1 | 0.8 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 0.2 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.1 | 0.8 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 0.6 | GO:0003700 | transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.1 | 0.7 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.1 | 1.6 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 0.3 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.1 | 0.4 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.2 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.6 | GO:0050664 | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664) |
| 0.1 | 8.3 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 0.6 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 0.3 | GO:0004325 | ferrochelatase activity(GO:0004325) |
| 0.1 | 0.1 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.1 | 1.4 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 3.7 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 0.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 1.3 | GO:0032813 | tumor necrosis factor receptor superfamily binding(GO:0032813) |
| 0.1 | 0.2 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.1 | 0.8 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.1 | 3.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 1.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 0.2 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.1 | 1.4 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 0.2 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.1 | 0.2 | GO:0070644 | 9-cis retinoic acid receptor activity(GO:0004886) vitamin D response element binding(GO:0070644) |
| 0.1 | 0.2 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.1 | 0.9 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 0.3 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.1 | 32.8 | GO:0005525 | GTP binding(GO:0005525) |
| 0.1 | 0.4 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.1 | 0.6 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.3 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.0 | 1.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.8 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.5 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.6 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 0.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 0.1 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.0 | 1.2 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 0.1 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.0 | 0.2 | GO:0004113 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113) |
| 0.0 | 0.2 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.0 | 0.3 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 0.2 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 0.0 | 4.7 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.0 | 0.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.0 | 0.2 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.0 | 0.2 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.0 | 0.9 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.8 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.2 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.0 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.0 | 0.8 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.0 | 1.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.2 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.0 | 0.4 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 3.0 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.4 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.3 | GO:0009008 | DNA-methyltransferase activity(GO:0009008) |
| 0.0 | 2.2 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.1 | GO:0008478 | pyridoxal kinase activity(GO:0008478) |
| 0.0 | 0.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 1.3 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.4 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 1.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 1.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 1.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.0 | 0.2 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 0.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.1 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.0 | 0.3 | GO:0036122 | BMP binding(GO:0036122) |
| 0.0 | 0.9 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 8.6 | GO:0060090 | binding, bridging(GO:0060090) |
| 0.0 | 1.2 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.1 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.0 | 0.1 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.0 | 2.3 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.1 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.0 | 0.5 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.7 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 2.6 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.2 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 0.1 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.2 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.0 | 0.1 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.0 | 0.9 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.6 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.2 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.0 | 3.0 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 0.1 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.0 | 0.1 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.0 | 0.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 0.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 16.1 | GO:0008289 | lipid binding(GO:0008289) |
| 0.0 | 0.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 1.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 5.4 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 0.3 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 0.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.1 | GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.4 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
| 0.0 | 0.1 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.0 | 0.2 | GO:0098505 | single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 5.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.2 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.1 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.0 | 0.2 | GO:0008233 | peptidase activity(GO:0008233) |
| 0.0 | 0.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 3.3 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.3 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.0 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.0 | 0.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 1.0 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 0.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.2 | GO:1901682 | sulfur compound transmembrane transporter activity(GO:1901682) |
| 0.0 | 0.1 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 39.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.2 | 15.7 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.2 | 8.0 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
| 0.2 | 2.5 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.1 | 0.8 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.1 | 4.2 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.1 | 5.9 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 6.3 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 6.4 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 2.6 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 2.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.6 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 3.7 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.1 | 5.5 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 1.7 | PID_IL23_PATHWAY | IL23-mediated signaling events |
| 0.1 | 3.3 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 4.8 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 1.2 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 4.2 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 0.5 | PID_IL27_PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.9 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 8.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.9 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.0 | 1.7 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.0 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.0 | 3.3 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 2.8 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.0 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 1.4 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 2.6 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.4 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.3 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.8 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.0 | 3.1 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.2 | PID_IL5_PATHWAY | IL5-mediated signaling events |
| 0.0 | 1.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.1 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.0 | 1.6 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.4 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.0 | 1.5 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.3 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 2.1 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 2.4 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.7 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.5 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.5 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.4 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.8 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 0.2 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.0 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.6 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.3 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.6 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.0 | 0.2 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 97.9 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.7 | 14.1 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.7 | 11.1 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.7 | 15.0 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.6 | 1.2 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.3 | 19.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.3 | 5.0 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.3 | 10.4 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.2 | 21.0 | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
| 0.2 | 3.4 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.2 | 3.1 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.2 | 2.1 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
| 0.2 | 2.0 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.2 | 6.2 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.2 | 3.4 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.2 | 11.3 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
| 0.2 | 4.0 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.2 | 9.8 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 4.6 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 6.1 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 2.5 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.1 | 4.4 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 4.4 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 3.5 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 2.2 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 9.2 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 8.3 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 6.1 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 4.2 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 1.2 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 7.3 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
| 0.1 | 1.5 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 1.0 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 3.7 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 1.3 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 2.1 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 5.8 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 1.2 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.8 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 1.0 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.0 | 0.7 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.5 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.6 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.5 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.0 | 1.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 3.5 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 1.0 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.1 | REACTOME_CD28_CO_STIMULATION | Genes involved in CD28 co-stimulation |
| 0.0 | 0.9 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.6 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 1.0 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.0 | 1.6 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.7 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.4 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.1 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.2 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.6 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 0.5 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.8 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.5 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.3 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.5 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.2 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 1.0 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.3 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.1 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.0 | 1.3 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.8 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.0 | 0.6 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
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